• elafin
  • The disappeared sequence carries the key amino acid residues Val-227 and Thr-239, which contribute to the substrate specificity of elastase I (highlighted in Figure 3), as well as five of the eight amino acids involved in the primary contact of the elafin(inhibitor)/elastase complex formation. (wikipedia.org)
  • Gene
  • The gene encoding neutrophil elastase, ELA2, consists of five exons. (wikipedia.org)
  • Elastase 1 is slightly inhibited above 150 mM NaCl Mutations of the CELA1 gene were suspected to be associated with diffuse nonepidermolytic palmoplantar keratoderma (diffuse NEPPK). (wikipedia.org)