AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceNamed GroupsHealth Care
HLA AntigensAntigensSerotypingAntigens, BacterialAntigens, NeoplasmHLA-B AntigensHLA-DR AntigensHLA-A AntigensAntigens, SurfaceLeukocytesAntigens, ViralHistocompatibility TestingLeukocyte RollingHistocompatibility Antigens Class IHLA-DQ AntigensHLA-DRB1 ChainsHLA-DQ beta-ChainsHLA-C AntigensHLA-G AntigensAntigens, CDMolecular Sequence DataAllelesEpitopesAntibodies, MonoclonalHistocompatibility Antigens Class IIHLA-A2 AntigenLeukocyte CountHLA-D AntigensAntigens, ProtozoanAntigens, Polyomavirus TransformingT-LymphocytesAntigens, FungalAmino Acid SequenceO AntigensHistocompatibility AntigensChemotaxis, LeukocyteHLA-B52 AntigenHLA-DR Serological SubtypesCross ReactionsGenes, MHC Class IHLA-B44 AntigenT-Lymphocytes, CytotoxicEnzyme-Linked Immunosorbent AssayAntigens, HelminthReceptors, Antigen, T-CellH-2 AntigensHaplotypesHLA-DP beta-ChainsHistocompatibilityGenes, MHC Class IIIsoantibodiesStreptococcus pneumoniaeHLA-DR3 AntigenCell LineGenotypeCarcinoembryonic AntigenImmunoglobulin GLymphocyte ActivationFlow CytometryMajor Histocompatibility ComplexHLA-DR2 AntigenBase SequenceAntigens, Viral, TumorHLA-B27 AntigenAntibodies, BacterialAntibody SpecificityHLA-A24 AntigenGene FrequencyMice, Inbred BALB CPolymerase Chain ReactionHLA-B8 AntigenHLA-DP AntigensHLA-B18 AntigenPneumococcal InfectionsPeptidesNeutrophilsAntigens, CD8Genetic Predisposition to DiseaseReceptors, KIRProliferating Cell Nuclear AntigenMice, Inbred C57BLCells, CulturedHLA-B35 AntigenHLA-DR4 AntigenHLA-A1 AntigenPolysaccharides, BacterialAntigens, CD15Antigens, CD45CD8-Positive T-LymphocytesHLA-B51 AntigenAntigens, CD3Receptors, Antigen, B-CellB-LymphocytesEpitopes, T-LymphocyteGraft RejectionProstate-Specific AntigenTransplantation, HomologousCell AdhesionInterferon-gammaBacterial Capsules
AdenovirusHistocompatibilityAntibodiesMoleculesHumanProteinsShigellaPeptideProteinRotavirusAntigenicGenotypesInfluenzaBindsGenesInfectionColiImmune systemFecal leukocytesPolymorphonuclear leukocytesInteractionsPeripheral Blood LeukocytesDendriticVaccinesDetectionEpitopeMechanismsPredominantlyViralDonorsExaminationMediatorsLymphocytesCellsInduceSarcoidosisIsolationExudatesRespiratoryMethodsIllnessReactionIndividualJournalRiskPopulation
Adenovirus5
  • We describe 3 culture-proven cases of adenovirus serotype 14 infection in New Brunswick, Canada, during the summer of 2011. (cdc.gov)
  • Originally discovered in 1955, human adenovirus serotype 14 (HAdV-14) had rarely been reported in medical literature for over 30 years. (cdc.gov)
  • Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction. (research.com)
  • Adenovirus antigens can be detected by enzyme immunoassay. (medscape.com)
  • Objective -To detect bovine adenovirus serotype 7 (BAV-7) infections in calves by use of viral isolation and serologic testing. (avma.org)
Histocompatibility2
Antibodies9
  • These particular antigens stimulate multiplication of T-helper cells (also called CD4-positive T cells), which in turn stimulate antibody-producing B-cells to produce antibodies to that specific antigen. (wikipedia.org)
  • Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody-antigen immune complexes and immunoproteins or Fc receptor expressing immune effector cells. (frontiersin.org)
  • Antibodies Specific to Antigens of Bartonella henselae and Use of These Antigens in Immunoassays. (genesisbiotechgroup.com)
  • Tests included viral isolation in cell culture from peripheral blood leukocytes (PBL) and detection of serum BAV-7 antibodies by use of microtitration viral neutralization. (avma.org)
  • GAS M proteins share epitopes (antigenic-determinant sites that are recognized by antibodies) with proteins found in synovium, heart muscle, and heart valve, suggesting that molecular mimicry by GAS antigens from rheumatogenic strains contributes to the arthritis, carditis, and valvular damage. (merckmanuals.com)
  • The process begins when an antigen induces the formation of IgE antibodies, which bind firmly with their Fc portion to the basophils and mast cells. (periobasics.com)
  • Re-exposure to antigen causes cross-linkage of the antibodies on the surface of mast cells. (periobasics.com)
  • The sensitization phase is the first exposure of antigen which triggers the production of antibodies. (periobasics.com)
  • Antibodies to somatic antigens and exotoxins also contribute to recovery. (tdmuv.com)
Molecules4
  • T-cells require presentation via MHC molecules to recognize foreign antigens-a requirement known as MHC restriction. (wikipedia.org)
  • Det innebär att de flesta av There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a Den huvudsakligen genetiska riskfaktoren för AS är HLA B27 som finns hos B. vid långvarig inflammatorisk ryggsmärta i senare skede Penttinen, MA. (web.app)
  • I have used structural biology to explain pre-T-cell receptor (TCR) self-association in T-cell development, and how the TCR specifically recognises polymorphic Human Leukocyte Antigen (HLA) molecules in the context of viral immunity and aberrant T-cell reactivity. (cardiff.ac.uk)
  • MHC class II molecules are specialized peptide receptors that play a critical role in initiating and regulating immune responses by binding peptide fragments that are 10-30 amino acids long [ 1 ] and present them on the surface of antigen-presenting cells for recognition by CD4 + T cells. (biomedcentral.com)
Human16
  • The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for regulation of the immune system. (wikipedia.org)
  • Sarcoidosis development during ulcerative colitis remission in a patient with a susceptible human leukocyte antigen serotype. (cdc.gov)
  • We hypothesized that many tumor associated antigens (Ag) are readily susceptible to immune attack, but only in the context of identifying the tumor antigen epitopes that can reliably initiate an immune response, regardless of individual patient human leukocyte antigen (HLA) haplotype restrictions. (ndltd.org)
  • In his study, Epitope, Cytotoxic T cell and Human leukocyte antigen is inextricably linked to Immune system, which falls within the broad field of Virology. (research.com)
  • HLA B27 (human leukocyte antigen) is a protein found on the surface of white blood cells of certain individuals. (web.app)
  • The protein is called human leukocyte antigen B27 (HLA-B27). (web.app)
  • Human leukocyte antigens (HLAs) are proteins that help the body's immune system tell the difference between its own cells and foreign, harmful substances. (web.app)
  • HLA-B27 stands for human leukocyte antigen B27. (web.app)
  • 2023. Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02 . (cardiff.ac.uk)
  • Effect of Escherichia coli β- hemolysin on human peripheral leukocyte viability in vitro. (microbiologyresearch.org)
  • Novel risk human leukocyte antigen (HLA) allotypes for different subgroups of spondyloarthritis (SpA) were identified in an Italian population, according to findings from a study published in Journal of Clinical Medicine . (rheumatologyadvisor.com)
  • Typing for human leukocyte antigen-B27 is appropriate for patients with recurrent anterior uveitis. (aafp.org)
  • Overall primary concerns are: extrapolating human clinical studies, seeding durable effective T cell resident memory (Trm), population human leucocyte antigen (HLA) coverage, and the potential for T cell-mediated immune escape. (mdpi.com)
  • Patient characteristics, such as human leukocyte antigen (HLA) type, immunosuppression (e.g. (kidsnewtocanada.ca)
  • This phase Ib trial evaluated the safety and immunogenicity of human serotype-5 Ad-vectored tuberculosis (TB) vaccine (AdHu5Ag85A) delivered to humans via inhaled aerosol or i.m. injection.MethodsThirty-one healthy, previously BCG-vaccinated adults were enrolled. (bvsalud.org)
  • The protection against SARS-CoV-2 induced by BCG vaccination may be mediated by cross-reactive T cell lymphocytes, which recognize peptides displayed by class I Human Leukocyte Antigens (HLA-I) on the surface of infected cells. (bvsalud.org)
Proteins5
  • The proteins encoded by certain genes are also known as antigens, as a result of their historic discovery as factors in organ transplants. (wikipedia.org)
  • Aside from the genes encoding the six major antigen-presenting proteins, many other genes, many involved in immune function, located on the HLA complex. (wikipedia.org)
  • Proteins from the pathogen are digested into small pieces (peptides) and loaded on to HLA antigens (to be specific, MHC class II). (wikipedia.org)
  • This test looks for HLA-B27, which are proteins called antigens. (web.app)
  • These disorders are characterized by abnormally strong Th2 responses against environmental antigens such as pollen, foods, insect proteins, some drugs, and so on. (periobasics.com)
Shigella1
  • Increasing the affinity of an O-antigen polysaccharide binding site in Shigella flexneri bacteriophage Sf6 tailspike protein. (mpg.de)
Peptide1
  • His Capsid study combines topics from a wide range of disciplines, such as Plasma protein binding, Immune system, Antigen, Peptide sequence and Peptide. (research.com)
Protein5
  • This mechanistically rational antigen selection sequence, effective even for unvaccinated donors, regardless of HLA-haplotype, enables rapid identification of tumor protein regions relevant for cancer immunology, including adoptive immunotherapy, vaccines, and even identification of tumor neo-antigens unique to each patient. (ndltd.org)
  • HLA-B27 antigen HLA-B27 is a blood test to look for a protein that is found on the surface of white blood cells. (web.app)
  • Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions. (mpg.de)
  • Conformational insights into recognition mechanism of O-antigen polysaccharides by tailspike protein. (mpg.de)
  • Higher attack rates occur with certain streptococcal M protein serotypes and a stronger host immune response (likely resulting from as-yet-uncharacterized genetic tendencies). (merckmanuals.com)
Rotavirus1
  • Rotavirus antigen can be identified by enzyme immunoassay and latex agglutination assay of the stool. (medscape.com)
Antigenic1
  • One such mechanism is antigenic variation, in which the antigens of B. burgdorferi exposed to the immune system can change over time, either through epigenetic modification, DNA recombination, or mutually exclusive expression (8). (insidescientific.com)
Genotypes2
  • This review addresses vector distribution, dengue outbreaks, circulating serotypes and genotypes, and prevention approaches being utilized in Brazil. (hindawi.com)
  • Allied Hospital, Fais- four genotypes, but only one serotype. (who.int)
Influenza1
  • When compared with ADV-negative and influenza-positive patients, those with ADV infections showed significantly elevated serum CRP concentrations and left-shifted leukocyte counts. (webmedcentral.com)
Binds2
  • An antigen binds to IgE on the surface of mast cells causing the release of chemical mediators. (periobasics.com)
  • CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. (thermofisher.com)
Genes1
  • The regulation of metabolic genes and major virulence genes indicate that the dominant antigens might differ during the infection process and that vaccines based on these antigens might allow establishment of a precise and targeted immune response during the early phase of infection. (biomedcentral.com)
Infection5
  • E. coli serotype O5 factor for the development of urinary tract was the most prevalent (29.3%) followed by infection (UTI) [ 1-3 ]. (who.int)
  • Here, we infected specific pathogen-free Mus musculus with App serotype 7 by intranasal inoculation to construct an acute hemorrhagic pneumonia infection model and isolated the infected lungs for analysis of the interactions by dual RNA-seq. (biomedcentral.com)
  • Enteric fever is an acute, life-threatening, febrile infection caused by Salmonella enterica serotypes Typhi, Paratyphi A and Paratyphi B. Each year, there are an estimated 22 million cases and 200,000 related deaths worldwide due to Salmonella typhi . (kidsnewtocanada.ca)
  • C. neoformans was categorized into serotypes A and D whereas C. gattii was classified into the serotypes B and C. Inhalation of spores is a primary route of infection that mainly affects immunocompromised persons, such as HIV-infected patients, organ transplant recipients, and patients receiving corticosteroid or immunosuppressive agents. (biomedcentral.com)
  • Some hours later, the antigen is injected which causes wheal and flare reaction (Not done presently because of transmission of infection). (periobasics.com)
Coli1
  • However, presence of fecal leukocytes eliminates consideration of enterotoxigenic E coli, Vibrio species, and viruses. (medscape.com)
Immune system3
  • Predicting which (fragments of) antigens will be presented to the immune system by a certain HLA type is difficult, but the technology involved is improving. (wikipedia.org)
  • The presence of antigens on the surface of cells allows the immune system to distinguish its own cells from foreign cells. (web.app)
  • Recently my team has provided a structural basis of how vitamin B metabolites can be presented and recognised by the immune system, revealing a new class of antigen. (cardiff.ac.uk)
Fecal leukocytes1
Polymorphonuclear leukocytes2
Interactions1
  • They are then displayed by the antigen-presenting cells to CD4+ helper T cells, which then produce a variety of effects and cell-to-cell interactions to eliminate the pathogen. (wikipedia.org)
Peripheral Blood Leukocytes1
Dendritic1
  • Gene modified dendritic cells (DC) are able to modulate DC functions and induce therapeutic immunity or tolerance in an antigen-specific manner. (biomedcentral.com)
Vaccines1
  • As a consequence, pneumococcus has developed efficient antibiotic resistance, and the use of vaccines covering a limited number of serotypes such as Pneumovax ® and Prevnar ® results in the expansion of non-covered serotypes. (biomedcentral.com)
Detection1
  • Results were also negative for urinary antigen detection for pneumococcus and Legionella spp. (cdc.gov)
Epitope1
  • Utilizing known HLA-serotype frequencies and setting a threshold of ninety percent of population coverage, regardless of race or ethnicity, twenty-nine different HLA-DRB1 haplotypes were chosen for antigen prediction utilizing the open source epitope prediction algorithm netMHCIIpan. (ndltd.org)
Mechanisms2
  • 2023. CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms . (cardiff.ac.uk)
  • The Fc receptor-dependent function of antibody-dependent cellular phagocytosis (ADCP) provides mechanisms for clearance of virus and virus-infected cells, as well as for stimulation of downstream adaptive immune responses by facilitating antigen presentation, or by stimulating the secretion of inflammatory mediators. (frontiersin.org)
Predominantly2
  • Enteroinvasive infections of the large bowel cause leukocytes, predominantly neutrophils, to be shed into stool. (medscape.com)
  • Some functions, such as neutralization, mainly depend on interaction of the Fv domain ( Figure 1A ) with antigen and are therefore predominantly Fc domain independent. (frontiersin.org)
Viral1
Donors1
  • Between 2008 and 2013, a total of 113 consecutive patients with symptomatic peripheral E/A and 318 HLA-I and HLA-II serotyped healthy donors as control participants were included. (rheumatologyadvisor.com)
Examination2
  • 41 years, with a mean age of 27.0 (standard examination, nitrite reductase, leukocyte deviation 4.9) years. (who.int)
  • Histological examination of gingivitis or periodontitis lesions reveals that the polymorphonuclear leukocyte (PMN) appears to play a key role in the maintenance of the periodontal health (3). (bvsalud.org)
Mediators1
  • Fc receptor-dependent antibody functions are also involved in activation of downstream adaptive immune responses by facilitating antigen presentation or by stimulating the secretion of inflammatory mediators ( 12 , 13 ). (frontiersin.org)
Lymphocytes3
Cells5
  • Self-antigens are suppressed by regulatory T cells. (wikipedia.org)
  • When a foreign pathogen enters the body, specific cells called antigen-presenting cells (APCs) engulf the pathogen through a process called phagocytosis. (wikipedia.org)
  • The activation phase is when re-exposure of antigen causes the release of contents of basophils and mast cells. (periobasics.com)
  • Increased production of interleukins, failure of regulation of T-cell level, increased IgE synthesis, enhanced uptake of antigen and hyperactivity of target cells. (periobasics.com)
  • Re-entry of antigen into the body causes the cross-linkage of antigen on the surface of mast cells which causes the release of substances. (periobasics.com)
Induce1
  • Only serotypes 40 and 41 are able to induce diarrhea. (medscape.com)
Sarcoidosis1
Isolation1
  • Procedures -PI status was determined by use of an antigen-capture ELISA (ACE) and confirmed by use of a second ACE, reverse transcriptase-PCR assay of sera, immunohistochemical analysis, and virus isolation from sera. (avma.org)
Exudates1
Respiratory1
  • Gram staining of the respiratory specimen was notable for its abundance of leukocytes and absence of bacteria. (cdc.gov)
Methods1
  • Methods and Compositions for Detecting Serotypes of Chlamydia trachomatis Capable of Causing Lymphogranuloma Venereum. (genesisbiotechgroup.com)
Illness1
  • While there has been no definitive association of the distinct DENV types with clinical course of disease, there are reports suggesting that DENV-2 and DENV-3 cause severe disease more frequently than the other serotypes and that DENV-4 causes a milder illness [ 23 , 24 ]. (hindawi.com)
Reaction1
Individual1
  • Within haematopoietic stem cell hair transplant, on the basis of completely individual leukocyte antigen (HLA)-matched contributor beneficiary frames, negative effects similar to graft vs . leukaemia and also graft compared to host tend to be seen and hard to manage. (casr-signal.com)
Journal1
Risk1
  • The presence of HLA B27 (8% of the population) is associated with a higher risk of developing certain autoimmune diseases such as ankylosing spondylitis HLA-B27, humani (ljudski) leukocitni antigen, , (engl. (web.app)
Population1
  • About 50% of the population generates an IgE response to airborne antigens, which are encountered on the mucosal surfaces (Lining of the nose, Lung and Conjunctiva). (periobasics.com)