Myelodysplastic SyndromesMyeloproliferative DisordersJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialAnemia, RefractoryLeukemia, Myelomonocytic, ChronicReceptors, ThrombopoietinBone Marrow NeoplasmsAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteThrombocytosisSyndromeLeukemia, MyeloidLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeBone MarrowLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticMutationLeukemiaChromosomes, Human, Pair 5Proto-Oncogene Proteins c-cblHematologic NeoplasmsSplenomegalyHematopoietic Stem CellsLeukemia, Myelogenous, Chronic, BCR-ABL PositiveBlast CrisisAzacitidineKaryotypingChromosome AberrationsPhiladelphia ChromosomePrognosisBone Marrow DiseasesPreleukemiaHematologyMonosomyDNA Mutational AnalysisMyeloid Progenitor CellsBone Marrow CellsJanus KinasesTreatment OutcomeChromosomes, Human, Pair 7ThalidomideCell Transformation, NeoplasticSTAT5 Transcription FactorMegakaryocytesAcute DiseaseMegakaryocyte Progenitor CellsMegakaryocyte-Erythroid Progenitor CellsDisease ProgressionTranslocation, GeneticNeoplasms, Second PrimaryCytogenetic AnalysisFusion Proteins, bcr-ablPancytopeniaAnemia, AplasticMutation, MissenseClonal EvolutionChromosome DeletionMyelopoiesisAntineoplastic AgentsProto-Oncogene ProteinsGranulocyte Precursor CellsHematopoiesisAmino Acid SubstitutionProtein Kinase InhibitorsPoint MutationCytogeneticsCore Binding Factor Alpha 2 SubunitOncogene Proteins, FusionHematopoietic Stem Cell TransplantationDown SyndromeGene Knock-In TechniquesTrisomyChromosomes, Human, Pair 8Antigens, CD34NeoplasmsCell ProliferationAntimetabolites, AntineoplasticDNA-Binding ProteinsErythropoietinSurvival AnalysisPhenotypeIron OverloadLeukemia, Myelomonocytic, AcutePrecursor Cell Lymphoblastic Leukemia-LymphomaCytarabineIn Situ Hybridization, FluorescenceGranulocytesExonsBone Marrow ExaminationTransplantation, HomologousGene Expression Regulation, LeukemicChromosomes, Human, Pair 20Polymerase Chain ReactionBone Marrow TransplantationBlood Cell CountErythrocyte Transfusion