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  • lymphoma
  • Exposure to benzene, an important industrial chemical and component of gasoline, is a widely recognized cause of leukemia, but its association with non-Hodgkin lymphoma (NHL) is less clear. (aacrjournals.org)
  • Further, because benzene is similar to alkylating drugs and radiation in producing leukemia, it is plausible that it might also produce lymphoma as they do and by similar mechanisms. (aacrjournals.org)
  • Although benzene is a widely recognized cause of leukemia, the association of benzene with non-Hodgkin lymphoma (NHL) is less clear. (aacrjournals.org)
  • Studies in Turkish shoe workers by Aksoy and others in the 1970s and 1980s were instrumental in establishing the relationship between benzene and leukemia, but these studies also identified 11 cases of lymphoma associated with occupational benzene exposure ( 2 ). (aacrjournals.org)
  • Myeloid
  • The PI3K/Akt pathway plays an important role in promoting B-cell survival and protecting against BCR-induced cell death by inducing the expression of antiapoptotic proteins, such as myeloid cell leukemia-1 (Mcl-1) and X-linked inhibitor of apoptosis protein (XIAP), and inactivating cellular targets involved in the induction of apoptosis, such as BAD (Bcl 2 antagonist of cell death) and caspase-9. (bloodjournal.org)
  • Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells. (wikipedia.org)
  • evidence
  • Epidemiological evidence shows a clear link between lung cancer and high concentrations of radon, with 21,000 radon-induced U.S. lung cancer deaths per year-second only to cigarette smoking-according to the United States Environmental Protection Agency. (wikipedia.org)
  • There is also evidence of a declining risk of cancer caused by radiation with increasing age, but the magnitude of this reduction above the age of 30 is uncertain. (wikipedia.org)
  • mortality
  • carried out a study (7) to compare incidence and mortality of leukemia in nine different districts. (stopumts.nl)
  • More alarming still, a more pronounced association was observed with mortality from leukemia than incidence. (stopumts.nl)
  • Studies of the survival and causes of death of the control groups of mice and dogs, which were not exposed to radiation, were the basis of the development by S. Jay Olshansky and Bruce A. Carnes of their biodemographic theory of intrinsic mortality. (wikipedia.org)
  • tumor
  • Meruelo, D., A role for elevated H-2 antigen expression in resistance to RadLV-induced leukemogenesis: Enhancement of effective tumor surveillance by killer lymphocytes, J. Exp. (springer.com)
  • Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. (wikipedia.org)
  • To spare normal tissues (such as skin or organs which radiation must pass through to treat the tumor), shaped radiation beams are aimed from several angles of exposure to intersect at the tumor, providing a much larger absorbed dose there than in the surrounding, healthy tissue. (wikipedia.org)
  • lung
  • For example, if a person who uses tobacco heavily develops lung cancer, then it was probably caused by the tobacco use, but since everyone has a small chance of developing lung cancer as a result of air pollution or radiation, there is a small chance that the cancer developed because of air pollution or radiation. (wikipedia.org)
  • thyroid
  • The authority denies that they were caused by the radiation released from the TEPCo NPP on the basis that thyroid cancer would emerge only 4-5 years after such an incident. (enenews.com)
  • Radiation therapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, acoustic neuromas, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, and prevention of keloid scar growth, vascular restenosis, and heterotopic ossification. (wikipedia.org)
  • Biological Effects
  • The ionization patterns in molecules, cells, tissues and the resulting biological effects are distinct from typical terrestrial radiation (x-rays and gamma rays, which are low-LET radiation). (wikipedia.org)
  • However, ground workers remain well below dose limits, and are largely exposed to low-LET radiation where the uncertainties of biological effects are much smaller than for space radiation. (wikipedia.org)
  • atomic
  • The paper also includes a summary of the current status of research on biomarkers of radiation exposure in the atomic bomb survivors. (biomedsearch.com)
  • Her main reason of death was from the radiation poisoning from the atomic bomb Little Boy. (wikipedia.org)
  • The classification of radioactive waste established by the International Atomic Energy Agency (IAEA) distinguishes six levels according to equivalent dose, specific activity, heat released and half-life of the radionuclides: Exempt waste (EW): Waste that meets the criteria for exclusion from regulatory control for radiation protection purposes. (wikipedia.org)
  • background radiation
  • If the linear model is correct, then natural background radiation is the most hazardous source of radiation to general public health, followed by medical imaging as a close second. (wikipedia.org)
  • It is often the single largest contributor to an individual's background radiation dose, and is the most variable from location to location. (wikipedia.org)
  • cell
  • Can Cell Tower Radiation Cause Cancer? (stopumts.nl)
  • Cell phones operate by sending and receiving radio frequency microwave radiation from their antennas to a nearby cell tower. (stopumts.nl)
  • Many leading independent researchers are of the view that the classification of cell phone/cell tower radiation should be upgraded to 'probable' human carcinogen. (stopumts.nl)
  • We show the oncogenic potential of those miRNAs in anchorage independence assay and confirm pri- miR-106-363 overexpression in 46% of human T-cell leukemias tested. (aacrjournals.org)
  • Furthermore, we identified myosin regulatory light chain-interacting protein, retinoblastoma-binding protein 1-like , and possibly homeodomain-interacting protein kinase 3 as target genes of this miRNA cluster, which establishes a link between these genes and T-cell leukemia for the first time. (aacrjournals.org)
  • The BCR is a key signaling molecule that triggers pathways that can induce B-cell proliferation, survival, differentiation, anergy, and apoptosis (for a review, see Niiro and Clark 12 ). (bloodjournal.org)
  • People may than go on to receive additional chemotherapy, radiation therapy, or a stem cell transplant. (wikipedia.org)
  • Renal cell cancer and melanoma are generally considered to be radioresistant but radiation therapy is still a palliative option for many patients with metastatic melanoma. (wikipedia.org)
  • Onconova suggests that Ex-Rad protects cells exposed to radiation against DNA damage, and that the drug's mechanism of action does not involve scavenging free radicals or arresting the cell cycle. (wikipedia.org)
  • In cell and animal models, Ex-RAD protects hematopoietic and gastrointestinal tissues from radiation injury when given either before or after exposure. (wikipedia.org)
  • Central nervous system (CNS) symptoms such cranial neuropathies due to meningeal infiltration are identified in less than 10% of adults and less than 5% of children, particularly mature B-cell ALL (Burkitt leukemia) at presentation. (wikipedia.org)
  • tissues
  • Later grants from NASA and additional funding from the Department of Energy enabled researchers at Northwestern University to make the data public through mouse and dog portals that permit radiation researchers to search for and request specific tissues from the studies' archives. (wikipedia.org)
  • populations
  • The RERF produces epidemiological and statistical information that helps to form our current knowledge of radiation related risk of cancer and other long-term health effects in human populations. (wikipedia.org)
  • gamma
  • While gamma rays are a form of highly-penetrating energy , the amount of gamma radiation emitted by DU is very low. (health.mil)
  • The Janus Experiments investigated the effects of exposure to neutron radiation and gamma radiation on mice and dogs. (wikipedia.org)
  • The ratio of a dose of high-LET radiation to a dose of x-rays or gamma rays that produce the same biological effect are called relative biological effectiveness (RBE) factors. (wikipedia.org)
  • increases
  • For typical survivors in the LSS, who received 0.005 Gy or greater (a mean dose of about 0.2 Gy), the lifetime leukemia risk increases to about 10 cases per 1,000 (or the relative risk is nearly 1.5). (rerf.jp)