• The outlook for someone with CML depends on the phase of the disease and the amount of blasts in the bone marrow, as well as other factors like the age of the patient, blood counts, and if the spleen is enlarged. (cancer.org)
  • In the accelerated phase, the number of CML cells is growing faster and causing symptoms such as fatigue, fever , weight loss and an enlarged spleen. (symptoma.com)
  • Patients in blast phase often have a fever , an enlarged spleen, weight loss, and generally feel unwell. (symptoma.com)
  • APPROVAL WAS BASED on findings in an open-label phase III trial (BFORE) in which 536 patients were randomized to receive oral bosutinib at 400 mg once daily (n = 268) or oral imatinib at 400 mg once daily (n = 268). (ascopost.com)
  • Along with the phase of CML, there are other factors that may help predict the outlook for survival. (cancer.org)
  • Patients whose CML is in an accelerated phase may have symptoms such as fever, poor appetite, and weight loss. (cancer.org)