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  • gene expression
  • Cryopreserved specimens are analyzed for NUP98 fusion to NSD1, JARID1A, and TOP1, myeloid/lymphoid or mixed-lineage leukemia (MLL)-rearrangements, and other gene expression profiling by reverse transcriptase polymerase chain reaction (RT-PCR) and karyotyping or fluorescence in situ hybridization (FISH). (clinicaltrials.gov)
  • myelogenous
  • In myeloid or myelogenous leukemias, the cancerous change takes place in a type of marrow cell that normally goes on to form red blood cells, some other types of white cells, and platelets. (wikipedia.org)
  • chronic
  • In addition, leukemias are classified as either acute, referring to a rapidly progressing disease that involves immature leukocytes, or chronic, referring to a slower proliferation involving mature white cells. (thefreedictionary.com)
  • and hairy cell leukemia (HCL), a chronic leukemia named for the cells' tiny hairlike projections. (thefreedictionary.com)
  • The first division is between its acute and chronic forms: Acute leukemia is characterized by a rapid increase in the number of immature blood cells. (wikipedia.org)
  • Chronic leukemia is characterized by the excessive buildup of relatively mature, but still abnormal, white blood cells. (wikipedia.org)
  • Whereas acute leukemia must be treated immediately, chronic forms are sometimes monitored for some time before treatment to ensure maximum effectiveness of therapy. (wikipedia.org)
  • Chronic leukemia mostly occurs in older people, but can occur in any age group. (wikipedia.org)
  • Chronic lymphocytic leukemia (CLL) most often affects adults over the age of 55. (wikipedia.org)
  • Diseases
  • They have an increased risk of a number of other health problems, including congenital heart defect, epilepsy, leukemia, thyroid diseases, and mental disorders. (wikipedia.org)