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  • Lineage
  • In primary mice, BCR-ABL1 expression induced an inflammatory-like state in the bone marrow and spleen, and mast cells were the only myeloid lineage specifically expanded by BCR-ABL1. (lu.se)
  • An important gene associated with Sm-Ahnmd is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways/superpathways are Hematopoietic cell lineage and Central carbon metabolism in cancer . (malacards.org)
  • stimuli
  • 9 - 15 ]) which depend on the tissue responses to mast cell mediators released both spontaneously and in response to trigger stimuli. (biomedcentral.com)
  • Factors that trigger mast cell degradation (non-steroidal anti-inflammatory drugs, physical stimuli, emotional stress, insect venom and certain foods) should be avoided. (malacards.org)
  • tumor cells
  • RATIONALE: Drugs used in chemotherapy, such as 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. (clinicaltrials.gov)