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  • cells
  • Two AMI that are benzoic acid derivatives (1f and 1h) were tested with an in vitro and ex vivo model to evaluate their reactivity with thiols and their activity in L5178-Y cells. (eurekaselect.com)
  • The increase in apoptosis on L5178-Y cells probably occurred, at least in part, by a decrease in glutathione levels and an increase in free radicals concentration. (eurekaselect.com)
  • Erik Andrade-Jorge, Marycarmen Godínez-Victoria, Luvia Enid Sánchez-Torres, Luis Humberto Fabila-Castillo and José G. Trujillo-Ferrara, "Aryl Maleimides as Apoptosis Inducers on L5178-Y Murine Leukemia Cells (in silico, in vitro and ex vivo Study)", Anti-Cancer Agents in Medicinal Chemistry (2016) 16: 1615. (eurekaselect.com)