AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
Leukemia Virus, MurineMoloney murine leukemia virusLeukemia Virus, BovineLeukemia Virus, FelineLeukemiaLeukemia, ExperimentalFriend murine leukemia virusLeukemia, Myeloid, AcuteAKR murine leukemia virusLeukemia, LymphoidHuman T-lymphotropic virus 1Leukemia, Lymphocytic, Chronic, B-CellVirus ReplicationAbelson murine leukemia virusReceptors, VirusLeukemia Virus, Gibbon ApeCell LineRauscher VirusGene Products, taxRetroviridaeRNA VirusesEnzootic Bovine LeukosisRetroviridae InfectionsMolecular Sequence DataGenes, ViralPrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Radiation-InducedDNA, ViralVaccinia virusVirus CultivationDefective VirusesLeukemia, T-CellRNA, ViralViral ProteinsProvirusesBase SequenceVirus AssemblyTumor Virus InfectionsAmino Acid SequenceRNA-Directed DNA PolymeraseCell Transformation, ViralAntigens, ViralGene Products, gagMice, Inbred AKRLeukemia-Lymphoma, Adult T-CellGammaretrovirusRetroviridae Proteins, OncogenicSimian virus 40Virus DiseasesVirus SheddingDeltaretrovirusVirus IntegrationLeukemia, Monocytic, AcuteLeukemia, Hairy CellHuman T-lymphotropic virus 2VirionOncogenic VirusesRepetitive Sequences, Nucleic AcidGene Expression Regulation, ViralLymphomaRadiation Leukemia VirusHylobatesPlant VirusesCells, CulturedDNA VirusesGene Products, envSindbis VirusHTLV-I InfectionsGenetic VectorsSarcoma Viruses, MurineAvian leukosis virusLeukemia, FelineGene Products, rexLeukemia L1210PreleukemiaPolymerase Chain ReactionLeukemia, B-CellT-LymphocytesMeasles virusInfluenza A Virus, H1N1 SubtypeMink Cell Focus-Inducing VirusesTransfectionCatsTerminal Repeat SequencesCattle DiseasesTranscription, GeneticGenes, pXRabies virusViral Envelope ProteinsDeltaretrovirus InfectionsInfluenza A Virus, H5N1 SubtypeMice, Inbred StrainsRecombination, GeneticBone MarrowSpecies SpecificityVirus ActivationGenes, envRetroviridae ProteinsTumor Cells, Cultured
Enzootic bovine leukosisLeukosisLymphomaLymphomasDefined chromosomeViral infectionsRetrovirusCharacterizationInfectionAntibodiesHTLVVaccinesAdultVaccineGenomesMalignanciesLymphocytesBelongsInhibitTumorApoptosisMalignancyCells promotesChildhoodParticlesParalysisMolecularBreast cancerStudiesAgentDiseasePatientReferenceRiskRussiaComplexCatsPatientsHighlyYearHostReach
Enzootic bovine leukosis2
Leukosis2
  • Bovine leukosis (B-cell leukemia/lymphoma), first described in 1871 in Lithuania, was believed to be an infectious disease because it spread through herds of cattle. (cdc.gov)
  • In 1969, a virus isolated from cultured lymphocytes of cattle in an afflicted herd was identified as the agent of bovine leukosis ( 1 ). (cdc.gov)
Lymphoma10
  • Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. (cdc.gov)
  • Bovine leukemia virus (BLV) infects cattle, integrates into host DNA as a provirus, and induces malignant B-cell lymphoma. (biomedcentral.com)
  • Less than 5% of cattle develop B-cell leukemia/lymphoma after a prolonged latency period [ 1 ]. (biomedcentral.com)
  • No specific sequence differences have been found between HTLV-1 recovered from patients with HAM, those with adult T-cell leukemia/lymphoma also caused by HTLV-1 (ATLL), and HTLV-1 carriers. (medscape.com)
  • Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype. (bordet.be)
  • Adult T-cell leukaemia-lymphoma: Pathogeny and clinical recommendations. (bordet.be)
  • 1975). Although the Epstein-Barr virus (EBV), a DNA virus of the herpes group, is implicated in some aspect of Burkitt's lymphoma, a B-cell disease (De- The 1980), the etiology of all the T -cell neoplasias is, as of yet, obscure. (science-connections.com)
  • When bovine leukemia virus (BLV), a causative agent of B-cellleukemia and lymphoma of cows, is injected into sheep, lymphoid leukemia and lymphoma, including a cutaneous form, occur which to our knowledge have not been subclassified (Olson 1979). (science-connections.com)
  • Overexpression of FLI1 in erythroblasts causes inhibition of differentiation and ultimately the development of pre-T cell lymphoblastic leukemia/lymphoma [ 11 ]. (biomedcentral.com)
  • We therefore investigated whether oleandrin or a N. oleander extract could inhibit virus transmission from a GFP-expressing HTLV-1+ lymphoma T-cell-line to huPBMCs in co-culture assays. (longdom.org)
Lymphomas2
  • Hence, in our initial attempts to develop cell lines from patients with T -cell neoplasias, we chose clinical subpopulations which represent a more mature form of disease, namely, the cutaneous T -cell lymphomas and leukemias and E-rosette positive T -cell ALL (Gupta and Good 1980). (science-connections.com)
  • In current clinical development, targeting CD19 + B cell malignancies, which include acute and chronic B-cell leukaemia and B-cell non-Hodgkin lymphomas (NHLs), with anti-CD19 CAR-T cells is one of the most advanced adoptive T-cell therapies and has been approved by the FDA. (nature.com)
Defined chromosome1
  • Simian virus 40-related antigens in three human meningiomas with defined chromosome loss. (vaccineinjury.info)
Viral infections1
  • show that this approach can detect characteristic changes that affect blood cells as a result of malaria, spherocytosis, bacterial and viral infections, and leukemia. (elifesciences.org)
Retrovirus4
  • HTLV-1 is a type C retrovirus, related to other human and primate lymphotropic viruses and the bovine leukemia virus. (medscape.com)
  • A novel retrovirus, human T -celllymphomaleukemia virus (HTLV), has been isolated from the fresh and cultured cells of two of these patients. (science-connections.com)
  • Subsequent characterization of this virus has shown that it is not significantly related to any known animal retrovirus, is not an endogenous (genetically transmitted) virus of man, and so far has been associated only with fresh or cultured T -cells from patients with T -cell neoplasia. (science-connections.com)
  • We therefore tested whether oleandrin or an extract from N. oleander could also inhibit the infectivity of the human T-cell leukemia virus type-1 (HTLV-1) -a related enveloped retrovirus and emerging tropical infectious agent. (longdom.org)
Characterization1
  • Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs. (bordet.be)
Infection6
  • Virus particles are difficult to detect and not used for transmission of infection. (wikipedia.org)
  • This vaccine thus induces a persistent anti-BLV immune response through maintaining a low level of infectivity, while preventing the risk of infection by the wild-type virus. (wikipedia.org)
  • The factors, such as hepatitis C virus infection, obesity, type Ⅱ diabetes and alcohol drinking, all contribute to the initiation of HCC [2]. (researchsquare.com)
  • We selected two viral systems: i) Bovine leukemia virus (BLV) which causes a highly contagious infection that occurs in a latent form that is striking in a number of key species of farm animals and represents a high risk [Rola-Łuszczak et al. (biomicsj.ru)
  • The infection with these viruses is a highly contagious for honeybees. (biomicsj.ru)
  • Importantly, these findings suggest oleandrin may have broad antiviral activity against enveloped viruses by reducing the incorporation of the envelope glycoprotein into mature particles, a stage of the infection cycle not targeted by modern HAART. (longdom.org)
Antibodies1
  • Association between the occurrence of antibodies to simian vacuolating virus 40 and bladder cancer in male smokers. (vaccineinjury.info)
HTLV5
  • It is closely related to the human T‑lymphotropic virus type 1 (HTLV-I). BLV may integrate into the genomic DNA of B‑lymphocytes as a DNA intermediate (the provirus), or exist as unintegrated circular or linear forms. (wikipedia.org)
  • The bovine leukemia virus (BLV) belongs to the family Retroviridae (genus Deltaretrovirus ) and is closely related to human T-cell leukemia viruses (HTLV-1 and II) [ 1 ]. (biomedcentral.com)
  • Since virions such as BLV, HTLV-1, and HTLV-2 are particularly unstable, viruses are primarily transmitted by the transfer of a cell carrying an integrated provirus. (biomedcentral.com)
  • Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. (bordet.be)
  • HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation. (bordet.be)
Vaccines1
Adult2
  • There are various clinical presentations of T -lymphocytic neoplasia in man, including approximately 25% of both childhood and adult acute lymphatic leukemia (Brouet et al. (science-connections.com)
  • For genetic variants of honeybee viruses a total of 270 adult bees from 90 bee colonies were collected from tick-borne defeat apiaries in the Ryazan region of Russia. (biomicsj.ru)
Vaccine4
  • In the city of Philippines the doctors noted an alarming spike in cases of both disease and deaths thereof after the vaccine was administered en masse. (currenthealthscenario.com)
  • Soon it was reported that one of the vaccine viruses in circulation had become virulent and was causing paralysis. (currenthealthscenario.com)
  • These recommendations represent the first statement by the Advisory Committee on Immunization Practices (ACIP) on the use of live, attenuated varicella virus vaccine -- VARIVAX -- manufactured by Merck and Company, Inc. and licensed in March 1995 for use in healthy persons greater than or equal to 12 months of age. (cdc.gov)
  • These recommendations represent the first statement by the Advisory Com- mittee on Immunization Practices (ACIP) on the use of live, attenuated varicella ® virus vaccine--VARIVAX --manufactured by Merck and Company, Inc. and li- censed in March 1995 for use in healthy persons 12 months of age. (cdc.gov)
Genomes1
Malignancies1
Lymphocytes1
  • In the case of the infectious cycle, viruses reach target lymphocytes by cell-to-cell transfer and establish by entry of viral single-stranded RNA, reverse transcription of the viral RNA, integration as a provirus into the host genome, expression of viral proteins, and budding of new virions. (biomedcentral.com)
Belongs1
  • The Orthopox family to which Small Pox belongs has many other viruses which can cause similar symptoms. (currenthealthscenario.com)
Inhibit4
  • In previous research, the authors demonstrated that the methanol extract of Artemisia vulgaris (AVM) has the ability to inhibit chronic myeloid leukemia (CML) cell proliferation. (spandidos-publications.com)
  • At present, there are no antiretroviral drugs that inhibit incorporation of the envelope glycoprotein into newlysynthesized virus particles. (longdom.org)
  • The botanical glycoside, oleandrin, derived from extracts of Nerium oleander , has previously been shown to reduce the levels of the gp120 envelope glycoprotein on human immunodeficiency virus type-1 (HIV-1) particles and inhibit HIV-1 infectivity in vitro . (longdom.org)
  • The botanical glycoside, oleandrin, and an extract of Nerium oleander have been shown to prevent the incorporation of the gp120 envelope glycoprotein of HIV-1 into mature virus particles and inhibit viral infectivity in vitro [ 1 ]. (longdom.org)
Tumor2
  • Simian virus 40-related DNA sequences in a human brain tumor. (vaccineinjury.info)
  • Since several animal RNA tumor viruses (Klein 1980) and cells of the putative human retroviruses isolated to date (Bronson et al. (science-connections.com)
Apoptosis1
Malignancy2
  • Therefore, besides the regulation of immune cells, NFAT2 also exerts modulatory effect of proliferation, invasion, metastasis and malignancy in breast cancer, lung cancer, melanoma and leukemia [13-15]. (researchsquare.com)
  • Chronic myeloid leukemia (CML) is a malignancy of the blood and bone marrow that affects children and adults. (spandidos-publications.com)
Cells promotes1
  • CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility. (libguides.com)
Childhood1
Particles1
  • However, the collected virus particles from treated cells exhibited reduced infectivity on primary human peripheral blood mononuclear cells (huPBMCs). (longdom.org)
Paralysis1
Molecular1
  • Currently actively developing information technologies (IT) are used to solve some important problems in the field of genetics of viruses and their molecular diagnostics. (biomicsj.ru)
Breast cancer1
  • It is observed that both biological effects and epidemiological effects appear to be the same or very similar from ELF exposure and from RF/MW exposures, including calcium ion efflux, melatonin reduction, DNA strand breakage, chromosome aberrations, leukaemia, brain cancer, breast cancer, miscarriage and neurological effects. (whale.to)
Studies1
  • Concerns that this virus might infect humans through exposure to food products from subclinically infected animals prompted 10 studies that used what were then (1975-1979) state-of-the-art immunologic methods to test serum samples from a collective total of 1,761 humans, including cancer patients, farm workers, and veterinarians ( 5 ). (cdc.gov)
Agent1
  • Geissler, E. "SV40 in human intracranial tumors: passenger virus or oncogenic 'hit-and-run' agent? (vaccineinjury.info)
Disease2
  • DHX15 was down-regulated when AML patients achieved disease remission or when leukemia cell lines were induced to differentiate. (oncotarget.com)
  • Varicella (i.e., chickenpox) is a highly contagious disease caused by varicella zoster virus (VZV). (cdc.gov)
Patient2
  • Derived from a patient with myelomonocytic leukaemia and subsequently exposed to Epstein Barr Virus (EBV). (hsanmartino.it)
  • Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia. (atlasclinicalfungi.org)
Reference1
  • Variations from the bovine reference sequence were infrequent and limited to base substitutions. (cdc.gov)
Risk1
  • Our finding of BLV in human tissues indicates a risk for the acquisition and proliferation of this virus in humans. (cdc.gov)
Russia1
  • Moreover, stockpiles of the Small Pox virus continue to remain with the USA and Russia and laboratory experiments have led to deaths. (currenthealthscenario.com)
Complex1
  • The cells show a complex karyotype with some characteristics of myelogenous leukaemia. (hsanmartino.it)
Cats1
  • Data on cats' positivity for Leishmania infantum , feline leukaemia virus (FeLV) and for feline immunodeficiency virus (FIV), available from the previous study, were included and examined. (biomedcentral.com)
Patients1
  • Isolation of virus related to SV40 from patients with progressive multifocal leukoencephalopathy. (vaccineinjury.info)
Highly1
  • DHX15 was highly expressed in hematopoietic stem cells and leukemia cells but was lowly expressed in mature blood cells. (oncotarget.com)
Year1
  • COLO 775 was established in 1990 from the peripheral blood cells of a 57 year old female with chronic myelogenous leukaemia. (hsanmartino.it)
Host1
  • The virus enters the host through the upper-respiratory tract. (cdc.gov)
Reach1
  • Secondary attack rates for this virus may reach 90% for susceptible household contacts. (cdc.gov)