DNA DamageDNA RepairComet AssayAtaxia Telangiectasia Mutated ProteinsUltraviolet RaysCell Cycle ProteinsDeoxyguanosineTumor Suppressor Protein p53Checkpoint Kinase 2DNA-Binding ProteinsDNA Breaks, Double-StrandedProtein-Serine-Threonine KinasesOxidative StressCell CycleGamma RaysTumor Suppressor ProteinsDNAApoptosisMethyl MethanesulfonateMutagensHistonesNuclear ProteinsGenomic InstabilityMutationDNA ReplicationG2 PhaseDNA AdductsCell Line, TumorPhosphorylationDNA Repair EnzymesDose-Response Relationship, RadiationCell LineCell SurvivalTime FactorsReactive Oxygen SpeciesHydrogen PeroxideDNA BreaksDNA GlycosylasesSignal TransductionDNA Breaks, Single-StrandedRadiation ToleranceProtein KinasesPoly(ADP-ribose) PolymerasesGenes, cdcCell Cycle CheckpointsCells, CulturedRad51 RecombinaseHeLa CellsSaccharomyces cerevisiae ProteinsS PhaseFibroblastsBRCA1 ProteinMitosisCell NucleusSaccharomyces cerevisiaeCell AgingMicronucleus TestsAntioxidantsAlkylating AgentsHydroxyureaMolecular Sequence DataX-RaysIntracellular Signaling Peptides and ProteinsChromatinDNA-Activated Protein KinaseModels, BiologicalDisease Models, AnimalG2 Phase Cell Cycle CheckpointsGuanineImmunohistochemistryMagnetic Resonance ImagingPyrimidine DimersOxidation-ReductionReplication Protein AMice, KnockoutProtein BindingDNA-Formamidopyrimidine GlycosylasePrecancerous ConditionsCell DeathRecombinational DNA RepairDNA HelicasesMice, Inbred C57BLSOS Response (Genetics)Dose-Response Relationship, DrugRecombination, GeneticRNA, Small InterferingPoly Adenosine Diphosphate RiboseBrain Damage, ChronicCarcinogensBlotting, WesternBase SequenceProliferating Cell Nuclear AntigenMitomycinProto-Oncogene Proteins c-mdm2SkinLymphocytesMicronuclei, Chromosome-DefectiveUbiquitinationCyclin-Dependent Kinase Inhibitor p21HCT116 Cells