• Atrial fibrillation, * atrial flutter , * sinus node dysfunction/atrial asystole, arrhythmias, atrial septal aneurysms, and the Chiari network are associated with left atrial thrombi. (medscape.com)
  • Left ventricular dysfunction is another risk factor for thromboembolism, as a result of blood stagnation and local myocardial injury. (nih.gov)
  • Moreover, it is not completely clarified if the presence of deep intertrabecular recesses causing stagnant blood flow can constitute per se a thrombogenic substrate even in absence of ventricular dysfunction. (nih.gov)
  • Background This study aimed to explore whether echocardiographic measurements during the early postoperative period can predict persistent left ventricular systolic dysfunction (LVSD) after aortic valve surgery in patients with chronic aortic regurgitation (AR). (ewha.ac.kr)
  • The association between increased arterial stiffness and left ventricular diastolic dysfunction (LVDD) may be influenced by left ventricular performance. (medsci.org)
  • brachial-ankle pulse wave velocity, P wave dispersion, left ventricular diastolic dysfunction. (medsci.org)
  • The cardiac mortality and morbidity were increased in heart failure patients with left ventricular diastolic dysfunction (LVDD) [ 1 , 2 ]. (medsci.org)
  • Oxidative stress and mitochondrial dysfunction are important mechanisms of ventricular remodeling, predisposed to the development of diabetic cardiomyopathy (DCM) in type 2 diabetes mellitus. (mdpi.com)
  • Foetal right atrial aneurysm and aortic coarctation with left ventricular dysfunction. (utah.edu)
  • However, a subset of patients do not improve, in which we suggest that concealed left ventricular dysfunction may play a causative role. (lu.se)
  • Wall motion was evaluated in the anterior, septal, apical, inferior and lateral portions of the left ventricle and compared to echo findings. (karger.com)
  • Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. (jax.org)
  • Catheter closure of atrial septal defect in the elderly (≥ 65 years). (lu.se)
  • Background Secundum atrial septal defect (ASD2) is one of the most common cardiac malformations diagnosed in adult life. (lu.se)
  • A ventricular septal defect (VSD) is an opening in the interventricular septum, causing a shunt between ventricles. (msdmanuals.com)
  • Tetralogy of Fallot Tetralogy of Fallot consists of 4 features: a large ventricular septal defect, right ventricular outflow tract obstruction and pulmonic valve stenosis, right ventricular hypertrophy, and over-riding. (msdmanuals.com)
  • Malalignment type ventricular septal defects are characterized by displacement of the conal or outlet septum. (msdmanuals.com)
  • Eccentric left ventricular hypertrophy and left atrial enlargement. (acvr.org)
  • The association of obstructive sleep apnea and left ventricular hypertrophy in obese and overweight children with history of elevated blood pressure. (utah.edu)
  • HCM is an inherited heart disorder which results in abnormal thickening of the heart walls (hypertrophy) that can lead to heart failure (HF), atrial fibrillation, and sudden death due to ventricular arrhythmias . (cdc.gov)
  • A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as "ace of spades" sign), and deep T-wave inversions in EKG. (bvsalud.org)
  • A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY. (bvsalud.org)
  • The role of left atrial (LA) function on exercise remains poorly understood in heart failure with preserved ejection fraction (HfpEF) despite its key role in optimizing left ventricular (LV) diastolic function. (uea.ac.uk)
  • What Is a Normal Left Ventricular Ejection Fraction? (medscape.com)
  • The ejection fraction of the left ventricle is the percentage of a evacuation of that chamber for cardiac cycle. (checkbiotech.org)
  • Assessment of left ventricular diastolic function is useful in risk stratification for patients with cardiovascular disease and can provide a diagnostic clue for heart failure with preserved ejection fraction. (medsci.org)
  • a decreased left ventricular ejection fraction was still apparent 6 weeks later. (medpagetoday.com)
  • Multiple logistic analysis demonstrated that postoperative left atrial volume index (LAVI) was the only independent predictor for persistent LVSD at 1 year after surgery in patients with postoperative LVSD (OR 1.180, 95% CI, 1.003-1.390, P = 0.046). (ewha.ac.kr)
  • Not only is the risk of death in patients with AF twice that of patients without AF, but AF can result in myocardial ischemia or even infarction, heart failure exacerbation, and tachycardia-induced cardiomyopathy if the ventricular rate is not well-controlled. (ahrq.gov)
  • The 2011 Focused Update on the Management of Patients with Atrial Fibrillation-by the American College of Cardiology Foundation (ACCF), the AHA, and the Heart Rhythm Society (HRS)-addressed the issue of strict versus lenient rate control in patients with AF. (ahrq.gov)
  • Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial. (bmj.com)
  • Q In patients with non-valvular atrial fibrillation requiring long term oral anticoagulant therapy, is fixed dose oral ximelagatran non-inferior to adjusted dose warfarin for preventing stroke and systemic embolism? (bmj.com)
  • Atrial fibrillation is the most common sustained cardiac arrhythmia, affecting approximately 2.2 million Americans1 and responsible for up to 30% of all ischemic strokes.2 It has a higher prevalence among elderly, hypertensive, and diabetic patients and among men, all of whom also have a higher prevalence of coronary artery disease (CAD). (hcplive.com)
  • Clinical trials have shown that HMG-CoA reductase inhibitors (statins) are effective for the primary and secondary prevention of CAD.3,4 We hypothesized that statin therapy might have a beneficial effect on the prevention of atrial fibrillation in patients with CAD because of shared risk factors. (hcplive.com)
  • We studied patients with stable chronic CAD, without a history of atrial fibrillation, enrolled in an ongoing observational study. (hcplive.com)
  • A total of 606 patients with at least 1 year's worth of follow-up data, complete medication information, and information on history of atrial fibrillation were eligible for this study. (hcplive.com)
  • Thirty-three patients with previous atrial fi-brillation were excluded, and 124 patients (20%) who had used nonstatin cholesterol-lowering drugs were excluded from the main analysis. (hcplive.com)
  • Sixteen patients with a non-invasively programmable pacemaker (Medtronic 2409) were examined with the unit in ventricular inhibited (VVI) and atrial synchronous ventricular inhibited (VDT/I) mode, respectively. (bmj.com)
  • To evaluate the diagnostic capabilities of a new, ultraportable 2D echo device to detect regional left ventricular wall motion abnormalities, 55 patients underwent an echocardiographic exam at the bedside prior to cardiac catheterization. (karger.com)
  • Left ventricular cineangiograms were obtained in biplane (60°LAO and 30° RAO) in 52 patients and in single plane (30° RAO) in 3 patients. (karger.com)
  • This study is designed to compare left ventricular diastolic function among patients divided by brachial-ankle pulse wave velocity (baPWV) and corrected P wave dispersion (PWDC) and assess whether the combination of baPWV and PWDC can predict LVDD more accurately. (medsci.org)
  • Screening patients by means of baPWV and PWDC might help identify the high risk group of elevated left ventricular filling pressure and LVDD. (medsci.org)
  • Impact of anticoagulation in patients with dementia and atrial fibrillation. (revespcardiol.org)
  • Factors associated with an increased risk of thromboembolic events in patients with atrial fibrillation (AF) include increasing age, rheumatic heart disease, poor left ventricular function, previous myocardial infarction, hypertension and a past history of a thromboembolic event. (aafp.org)
  • Localization of left atrial ganglionated plexi in patients with atrial fibrillation: techniques and technology. (springer.com)
  • In acute mitral regurgitation, patients are in sinus rhythm rather than atrial fibrillation and have little or no enlargement of the left atrium, no calcification of the mitral valve, no associated mitral stenosis , and in many cases little left ventricular dilation. (health.am)
  • RCM may manifest as a solitary abnormality, although restrictive filling patterns of the left ventricle can also be seen in patients with dilated or hypertrophic cardiomyopathy. (medscape.com)
  • NYHA deteriorated in 9 patients, despite reduced right ventricular size. (lu.se)
  • Importantly, stroke risk in HCM is independent of traditional risk stratification tools used for patients with atrial fibrillation. (cdc.gov)
  • Therefore, early detection is of paramount importance as initiation of anticoagulant therapy to reduce stroke risk is advised for all patients with HCM and atrial fibrillation, a recommendation that differs from individuals without HCM who have atrial fibrillation. (cdc.gov)
  • Chez les patients hypertendus, le taux de mortalité était plus élevé uniquement chez les patients admis pour un infarctus du myocarde avec sus-décalage du segment ST. Après ajustement des résultats en fonction des variables de référence, l'hypertension s'est révélé être un facteur prédictif indépendant de l'insuffisance cardiaque (OR = 1,31) et de l'accident vasculaire cérébral (OR = 2,47). (who.int)
  • Patients who experienced arrhythmia during HD had higher left ventricular mass and left ventricular mass index, lower post-dialysis K+ level, higher QTc and QTdc both before and after HD. (who.int)
  • The study sample was drawn from patients nant ventricular tachyarrhythmia [ 2 ]. (who.int)
  • Left atrial enlargement (LAE) or left atrial dilation refers to enlargement of the left atrium (LA) of the heart, and is a form of cardiomegaly. (wikipedia.org)
  • Morphologic findings include atrial enlargement without increased ventricular wall thickness or ventricular cavity dilation, the absence of eosinophilic infiltration, and the absence of pericardial disease. (medscape.com)
  • Echocardiography revealed moderate chronic degenerative valve disease with moderate left atrial and ventricular dilation. (avma.org)
  • The syndrome is caused by changes in the structure and function of certain cardiac ion channels and reduced expression of Connexin 43 (Cx43) in the Right Ventricle (RV), predominantly in the Right Ventricular Outflow Tract (VSVD), causing electromechanical abnormalities. (bvsalud.org)
  • Systolic time intervals did not differ between VVI and VDT/I pacing apart from an increase in left ventricular ejection time index with VDT/I pacing. (bmj.com)
  • Hemodynamically, left ventricular volume overload may ultimately lead to left ventricular failure and reduced cardiac output, but for many years the left ventricular end- diastolic pressure and the cardiac output may be normal at rest, even with considerable increase in left ventricular volume. (health.am)
  • Experimental model for paroxysmal atrial fibrillation arising at the pulmonary vein-atrial junctions. (springer.com)
  • Bettoni M, Zimmermann M. Autonomic tone variations before the onset of paroxysmal atrial fibrillation. (springer.com)
  • Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. (springer.com)
  • BrS is associated with an increased risk of syncope, palpitations, chest pain, convulsions, difficulty in breathing (nocturnal agonal breathing) and/or Sudden Cardiac Death (SCD) secondary to PVT/VF, unexplained cardiac arrest or documented PVT/VF or Paroxysmal atrial fibrillation (AF) in the absence of apparent macroscopic or structural heart disease, electrolyte disturbance, use of certain medications or coronary heart disease and fever. (bvsalud.org)
  • If the patient presents to with a history of atrial fib, whether persistent or intermittent, you are certain that they are at an increased risk for cardiac disease, presently, or in future. (checkbiotech.org)
  • We compared the effects of statin use with no cholesterol therapy at all, as well as nonstatin cholesterol-lowering therapy, on the development of atrial fibrillation. (hcplive.com)
  • This is probably related to decreased compliance of the ventricle and ultimately results in the development of atrial dilatation. (medscape.com)
  • Heart failure (HF) increases the risk of stroke and thrombo-embolism (TE) in non-valvular atrial fibrillation (NVAF), and is incorporated in stroke risk stratification scores. (nih.gov)
  • Relatonship between left ventricular diastolic pressure and myocardial segment length and observations on the contribution of atrial systole. (elsevierpure.com)
  • Typical hemodynamic characteristics include normal systolic function and equalization of increased ventricular end-diastolic pressures. (medscape.com)
  • Patient presentation/symptoms and ultrasound characteristics of left ventricular, left atrial, right ventricular, and right atrial thrombus are included. (gcus.com)
  • Noncompaction cardiomyopathy (NCCM) is a rare condition characterized by prominent trabeculae, deep intertrabecular recesses, and a left ventricular myocardium with a two-layered structure, characterized by a spongy endocardial layer and a thinner and compacted epicardial one. (nih.gov)
  • CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression. (jax.org)
  • Although other factors may contribute, left atrium size has been found to be a predictor of mortality due to both cardiovascular issues as well as all-cause mortality. (wikipedia.org)
  • Research suggests that left atrium size as measured by an echo-cardiograph may be linked to cardiovascular disease. (wikipedia.org)
  • Atrial fibrosis is one of the most fundamental mechanisms involved in the physiopathology of cardiovascular disease, which includes atrial fibrillation (AF) [ 1 , 2 ] and heart failure (HF) [ 3 ] . (medsci.org)
  • The outcome was the occurrence of atrial fibrillation during follow-up, verified through a review of records and confirmed by 12-lead electrocardiogram (ECG) or ambulatory ECG monitoring. (hcplive.com)
  • Left atrial enlargement can be mild, moderate or severe depending on the extent of the underlying condition. (wikipedia.org)
  • Over time, the repetitive stretching of the left atrium may result in a persistent left atrial enlargement. (wikipedia.org)
  • Characterizing the size of the left atrium according to its volume is preferred over a single linear dimension since enlargement can be different for different directions. (wikipedia.org)
  • For example, because of the smaller distance in the thoracic cavity between the sternum and spine, compared to the other directions, less room exists for enlargement of the left atrium along the anteroposterior axis. (wikipedia.org)
  • x-ray shows left atrial and ventricular enlargement. (health.am)
  • Mitral regurgitation leads to left atrial enlargement and may cause subsequent atrial fibrillation. (health.am)
  • the degree of left ventricular enlargement usually reflects the severity of regurgitation. (health.am)
  • Clinical Findings -Preanesthetic ECG revealed normal ventricular capture. (avma.org)
  • This means that you have a clue that there something bothering their left ventricle. (checkbiotech.org)
  • The net effect is an increased volume load on the left ventricle, and the presentation depends on the rapidity with which the lesion develops. (health.am)
  • Atrial myxoma , * cardiac sarcoma , endocardial fibroelastoma, and metastatic disease are associated with cardiac tumors and cardioembolic emboli. (medscape.com)
  • Cardiac tumors, chiefly left atrial myxoma, are a rare cause of mitral regurgitation. (health.am)
  • During left ventricular systole, the mitral leaflets do not close normally, and blood is ejected into the left atrium as well as through the aortic valve. (health.am)
  • In addition to sudden death, symptoms of HF occur with a lifetime incidence of ~70% in HCM , and approximately 5% of individuals will develop medically refractory HF that leads to premature death or the need for advanced HF therapies such as heart transplantation or a surgically implanted mechanical heart pump (left ventricular assist device, or LVAD). (cdc.gov)
  • P wave dispersion is not only a significant determinant of left ventricular performance, but is also correlated with LVDD. (medsci.org)
  • Sources of cardioembolic embolism include valvular diseases, left ventricular and atrial thrombi, cardiac tumors, and paradoxical emboli, as well as other sources. (medscape.com)
  • Prevention of atrial fibrillation: report from a National Heart, Lung, and Blood Institute workshop. (nature.com)
  • In any case, LAE can be diagnosed and measured using an echocardiogram (ECHO) by measuring the left atrial volume (LAVI). (wikipedia.org)
  • However, studies that have found LAE to be a predictor for mortality recognize the need for more standardized left atrium measurements than those found in an echo-cardiogram. (wikipedia.org)
  • The negative intrathoracic pressure may cause the left atrium to expand and stretch its walls during each OSA event. (wikipedia.org)
  • By approximating the shape of the left atrium as an ellipsoid, its volume can be calculated from measurements of its dimensions along three perpendicular directions. (wikipedia.org)
  • When it is chronic, the left atrium enlarges progressively, but the pressure in pulmonary veins and capillaries rises only transiently during exertion. (health.am)
  • This condition affects the function of the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. (medlineplus.gov)
  • We calculated the relative risks of developing atrial fibrillation and their accompanying 95% confidence intervals (CIs), which were estimated from a Cox proportional hazards regression model. (hcplive.com)
  • Yang D, Yuan J, Liu G, Ling Z, Zeng H, Chen Y, Zhang Y, She Q, Zhou X. Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 /Nuclear Factor-Kappa B Axis. (medsci.org)
  • To investigate whether the administration of renin-angiotensin system (RAS) inhibitors and statins could alleviate atrial fibrosis via platelet-derived growth factor (PDGF)/Rac1 /nuclear factor-kappa B (NF-κB) axis. (medsci.org)
  • Irbesartan or/and simvastatin can improve atrial fibrosis by regulating PDGF/Rac1/NF-κB axis. (medsci.org)
  • The specific mechanism responsible for atrial fibrosis remains unclear. (medsci.org)
  • Many recent studies in both animal models and humans have revealed that renin-angiotensin system (RAS) activation is one of the most vital mechanisms involved in atrial fibrosis [ 1 , 4 ] . (medsci.org)
  • In addition, other studies demonstrated that AngII activated platelet-derived growth factor-A (PDGF-A), a novel contributor to cardiac remodelling, to result in atrial fibrosis in pressure-overloaded mouse model [ 13 ] . (medsci.org)
  • Burstein et al [ 7 ] found that PDGF had a tendency to promote atrial fibrosis in dogs. (medsci.org)