• Amyotrophic lateral sclerosis (ALS), also known as Charcot's disease and Lou Gehrig's disease, is a disease of unknown cause characterized by slowly progressive degeneration of upper motor neurons (UMNs) and lower motor neurons (LMNs). (medscape.com)
  • Emergency physicians should be familiar with amyotrophic lateral sclerosis (ALS) and should consider the diagnosis in patients with motor symptoms and signs of hyperreflexia. (medscape.com)
  • Physical and occupational therapy and speech pathology consultations assist the patient with amyotrophic lateral sclerosis (ALS) in maintaining strength, daily living activities, and communication skills (as demonstrated in the image below). (medscape.com)
  • Patient with amyotrophic lateral sclerosis (ALS) using eye-gaze computer device to conduct business and communicate. (medscape.com)
  • Objective A recent neuroanatomical staging scheme of amyotrophic lateral sclerosis (ALS) indicates that a cortical lesion may spread, as a network disorder, both at the cortical level and via corticofugal tracts, including corticospinal projections providing direct monosynaptic input to α-motoneurons. (bmj.com)
  • Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the central nervous system that results in a progressive loss of motor function and ultimately death. (biorxiv.org)
  • Large expansions of a non-coding GGGGCC-repeat in the first intron of the C9orf72 gene are a common cause of both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). (nature.com)
  • Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder in which the loss of motor neurons in brain and spinal cord causes progressive weakness and paralysis, ultimately leading to death from respiratory failure 1 . (nature.com)
  • Amyotrophic lateral sclerosis and other motor neuron diseases are characterized by steady, relentless, progressive degeneration of corticospinal tracts, anterior horn cells, bulbar motor nuclei, or a combination. (msdmanuals.com)
  • Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease (MND). (msdmanuals.com)
  • Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which there is preferential loss of both the upper and lower motor neurons. (bmj.com)
  • They result from degeneration of the lateral corticospinal tracts in the spinal cord. (medscape.com)
  • Interruption of the lateral corticospinal tracts, the lateral spinal thalamic tract, and at times the posterior columns produces a picture of a spastic, weak leg with brisk reflexes and a strong leg with loss of pain and temperature sensation. (medscape.com)
  • Upper MNDs (eg, primary lateral sclerosis) affect neurons of the motor cortex, which extend to the brain stem (corticobulbar tracts) or spinal cord (corticospinal tracts). (msdmanuals.com)
  • A neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. (orpha.net)
  • Details of the patient's history aid in differentiating a common cold from conditions that require targeted therapy, such as group A streptococcal pharyngitis , bacterial sinusitis, and lower respiratory tract infections. (medscape.com)
  • Acute lower respiratory tract infections (ALRIs) are common and frequent group of diseases caused by a wide range of pathogens (viruses, bacteria, fungi or parasites) in which the possible anatomic site(s) extend from the trachea to the alveoli. (scirp.org)
  • Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
  • 2 Among the intrinsic hand muscles, wasting predominantly affects the 'lateral (thenar) hand' involving both median innervated muscles (abductor pollicis brevis (APB) and opponens pollicis) and ulnar innervated muscles (first dorsal interosseous (FDI), adductor pollicis and flexor pollicis brevis), with relative sparing of the hypothenar muscles (the abductor digiti minimi (ADM)) ( figure 1 ). (bmj.com)
  • Upper respiratory tract infection (URI) represents the most common acute illness evaluated in the outpatient setting. (medscape.com)
  • The nasal cavity is the most cephalic part of the respiratory tract. (nih.gov)
  • Infection is via the conjunctiva or upper respiratory tract with an incubation period of 6-10 days. (thepoultrysite.com)
  • It is indicated for the treatment of infections caused by susceptible organisms involving the respiratory tract. (medscape.com)
  • It is indicated for the prophylaxis or treatment of mild to moderately severe upper respiratory tract infections caused by organisms susceptible to low concentrations of penicillin G. (medscape.com)
  • 10. Purulent nasal infection, or upper respiratory tract infection within 2 weeks before the screening visit. (who.int)
  • Lower respiratory tract infection caused by Mycobacterium tuberculosis is not addressed in this document. (cdc.gov)
  • Acute exposure to 1,2-dichlorobenzene vapors may result in irritation of the eyes and respiratory tract. (cdc.gov)
  • 1,2-Dichlorobenzene is irritating to the eyes and respiratory tract. (cdc.gov)
  • The anterior spinothalamic tract (aka ventral spinothalamic tract) carries general touch or light touch sensations from the body. (neuroscientificallychallenged.com)
  • The main sensory nucleus receives its afferents (as the sensory root) from the semilunar ganglion through the lateral part of the pons ventral surface. (medscape.com)
  • In their course they pass just lateral to the lateral geniculate body (the lateral zone of Wernicke or area triangularis seen in horizontal sections cut through this region). (stanford.edu)
  • The effect of LSD (5 mcg-lmg) on the potentials associated with synaptic transmission in the lateral geniculate body was studied in 45 cats, some cats receiving more than one injection. (erowid.org)
  • It lies near the lateral angle of the fourth ventricle in the rostral part of the pons. (medscape.com)
  • We hypothesize that degeneration of subcortical regions, including the basal ganglia, is associated with damage of white matter tracts linking these affected regions. (frontiersin.org)
  • at least 1 present in 68% of subjects), anterior and posterior periventricular capping, diffuse posterior white matter hyperintensity, septal hyperintensity, corticospinal tract hyperintensity, and ventricular CSF flow artifacts. (ajnr.org)
  • The other nonfocal hyperintensities (anterior and posterior periventricular capping, diffuse parenchymal hyperintensity, septal hyperintensity, corticospinal tract hyperintensity, and CSF flow artifacts) were generally more common and prominent at 3T than at 1.5T. (ajnr.org)
  • Surrounding the nasal cavities are air-containing mucosal lined sinuses, which include the frontal sinuses (superior anterior), ethmoid sinuses (superior), paired maxillary sinuses (lateral), and sphenoid sinuses (posterior). (nih.gov)
  • However, the posterior hemithorax was accessible only when both subjects were placed in the lateral decubitus position. (sages.org)
  • In conclusion, we believe that the lack of good exposure to the posterior aspect of the thorax in the canine that is encountered because of the supine position can be overcome by the placing the subject in the lateral decubitus position. (sages.org)
  • 1 A typical cutaneous reaction manifests as macular lesions first appearing on the upper back and lateral neck, jaw, ears, palms, and soles. (oncologynurseadvisor.com)
  • Most bacterial nosocomial pneumonias occur by aspiration of bacteria colonizing the oropharynx or upper gastrointestinal tract of the patient. (cdc.gov)
  • LSD depressed or completely inhibited the repetitive discharge of the geniculate neurons caused by a large fibre optic tract volley. (erowid.org)
  • The anterior and lateral aspects of the thoracic cavity and mediastinum were adequately accessible with the animals in the supine position. (sages.org)
  • The axons emerge anterior to the sensory root from the lateral surface of the pons. (medscape.com)
  • Here, we constructed a whole-brain, three-dimensional (3D) map showing the tract pathways and targeting locations of these four motor cortical outputs in mice. (nature.com)
  • Remarkably, these motor cortical projections showed unique and separate tract pathways despite targeting similar areas. (nature.com)
  • The nucleus gives rise to the lateral vestibulospinal tract. (eur.nl)
  • The spinal tract is the sensory nucleus, primarily for pain and temperature. (medscape.com)
  • Microguided Endodontics: a case report of a maxillary lateral incisor with pulp canal obliteration and apical periodontitis. (bvsalud.org)
  • KEY LEARNING POINTS Using the Microguided Endodontics concept, a minimally invasive access was achieved up to the middle of the root, in a maxillary lateral incisor with pulp canal obliteration (PCO) and apical periodontitis . (bvsalud.org)
  • The maxillary lateral incisor is the most common site of occurrence. (bvsalud.org)
  • Dens invaginatus is a developmental change that may affect any dental element in the oral cavity, including permanent, deciduous, and supernumerary teeth, and the maxillary lateral incisor is the most common site of occurrence 1-4 . (bvsalud.org)
  • The lateral walls are spiral shaped mucosal folds that overlie the turbinates and sinus ducts draining into the ostia. (nih.gov)
  • Clinically, there were no complaints, no percussion pain or sinus tract. (bvsalud.org)
  • All of these paranasal sinuses, except the sphenoid, communicate with the nasal cavity via ducts that drain through ostia, which empty into spaces located on the lateral wall. (nih.gov)
  • Here, we report the preliminary findings of the transoral approach to access the thoracic cavity of 2 dogs placed in the supine and lateral decubitus positions.Method: Two dogs (weight, 8.1 and 8.4 kg) were used for this experiment. (sages.org)
  • A homemade metallic tube was used to create a working tract via the pretracheal and substernal planes to approach the thoracic cavity under endoscopic guidance. (sages.org)
  • Lateral neck radiograph demonstrates epiglottitis. (medscape.com)
  • The descending sensory fibers from the semilunar ganglion course through the pons and medulla in the spinal tract of CN V to end in the nuclei of this tract (as far as the second cervical segment). (medscape.com)
  • In addition, the descending sensory spinal tract receives somatic sensory fibers from CNs VII, IX, and X. (medscape.com)
  • but the skin is the most affected organ, with the GI tract and liver also commonly involved organs. (oncologynurseadvisor.com)
  • A prenatal diagnosis can be performed by measuring the alpha-fetoprotein produced by the foetal gastrointestinal tract and liver as well as foetal ultrasonography, which is considered the gold standard for diagnosis. (bvsalud.org)
  • It runs along the side of the lateral ventricle and is presumably deformed by ventricular enlargement. (ajnr.org)
  • It is located in the lateral funiculus and function to modulate pain transmission. (wikipedia.org)
  • LSD depressed and, in larger doses, blocked transmission through the lateral geniculate. (erowid.org)
  • BOL-148, bufotenin, mescaline and 5-hydroxytryptamine all blocked synaptic transmission in the lateral geniculate to varying degrees. (erowid.org)
  • Transmission is venereal in breeders, with transovarian and then lateral spread in meat animals. (thepoultrysite.com)
  • Guanine (G)-quadruplexes are highly stable nucleic acid secondary structures formed from short tracts of G-rich sequence associating together. (nature.com)
  • We used the central fluid percussion injury model (n = 18 and three controls) and the lateral fluid percussion injury model (n = 15 and three controls). (lu.se)
  • Diffusion tensor metrics of the segmented CST, including FA values, axial eigenvalues, and radial eigenvalues, were evaluated by using tract-specific analysis. (ajnr.org)
  • The right labia majora with surrounding erythema and bi- patient's symptoms had worsened despite complet- lateral inguinal lymphadenopathy. (cdc.gov)
  • The leaves of for asthma, it eases symptoms of intestinal the khat plant contain alkaloids structurally tract disorders [9] and maintains social con- related to amphetamine. (who.int)
  • The surgeon places his or her finger through this incision to protect the peritoneum (sac containing abdominal organs) as instruments pass through the lateral space to the spine. (ucsfhealth.org)
  • Extreme lateral interbody fusion (XLIF) is a minimally invasive procedure performed through the side of the body to treat spinal disorders and reduce long-term back or leg pain that has not responded to other treatments, such as steroid injections, physical therapy and pain medication. (ucsfhealth.org)
  • We aim to use fixel-based analysis to identify microstructural changes in the white matter tracts. (frontiersin.org)
  • Reductions in fixel-derived metrics occurs in major white matter tracts, noticeably in corpus callosum, internal capsule, and the corticospinal tract, which were closely co-localized with the regions of increased diffusivity in basal ganglia. (frontiersin.org)
  • Accumulation of β-amyloid precursor protein was observed in white matter tracts in both models in areas with preserved and reduced myelin staining. (lu.se)
  • National Mineral Resource Assessment 1998: Estimates of the number of undiscovered mineral resources of gold, silver, copper, lead, and zinc within identified permissive tracts (geographic areas in which mineral deposits may form). (usgs.gov)
  • O incisivo lateral superior permanente é o que apresenta maior envolvimento. (bvsalud.org)
  • Tract-specific analysis is 1 method of DTI data analysis. (ajnr.org)
  • Includes descriptions of 981 known occurrences and deposits as well as qualitative assessment of undiscovered resource potential in 84 permissive tracts. (usgs.gov)