Lassa fever. Medical search. Frequent questions

50 hospital staff members (including nofl uorescent antibody test using Vero those who had had contact with the cells infected with Lassa virus. (cdc.gov)
Humans usually become infected with Lassa virus from exposure to urine or feces of infected Mastomys rats, unique to several countries in Africa. (medscape.com)
About 80% of people who become infected with Lassa virus have no symptoms. (who.int)
In a paper published in the journal Proceedings of the National Academy of Sciences , UTMB's scientists document how a new drug from Zalgen Labs successfully cured cynomolgus monkeys infected with Lassa virus. (utmb.edu)
The results indicated Arevirumab-3 potentially could be used to treat humans infected with Lassa virus. (utmb.edu)
The rodent is often found in or around human habitats, and people become infected with Lassa virus through direct contact with rodent urine and stool. (nih.gov)
4/5 of people infected with Lassa virus will present no symptoms. (nursinganswers.net)

Diagnosis is difficult because it can be confused with other infections such as severe malaria, typhoid fever, and other viral hemorrhagic fevers. (medscape.com)
Lassa fever can be difficult to distinguish clinically from other viral hemorrhagic fevers, such as Ebola virus disease. (wikipedia.org)
Viral hemorrhagic fevers (VHFs) are a group of illnesses caused by four families of viruses. (medlineplus.gov)
While viral hemorrhagic fevers (VHFs), like Lassa fever, are very serious, they are not common in the U.S. However, it is important for healthcare providers to understand high consequence viruses, like Lassa fever, so they can appropriately diagnose and care for their patients. (netecweb.org)

Lassa fever is an acute viral haemorrhagic illness of 2-21 days duration that occurs in West Africa. (who.int)
Lassa fever is endemic to West Africa where these rats are common. (nih.gov)
Lassa fever is relatively common in West Africa including the countries of Nigeria, Liberia, Sierra Leone, Guinea, and Ghana. (wikipedia.org)
Reference Lassa fever is an often fatal arenavirus infection that occurs mostly in West Africa. (msdmanuals.com)
New research out of the University of Texas Medical Branch potentially points to an effective treatment for Lassa fever, a dangerous, often fatal disease common to much of West Africa but considered a major threat to global health. (utmb.edu)
Lassa virus has a high level of genetic diversity across much of West Africa," said Dr. Robert Cross, associate professor in the Department of Microbiology & Immunology and one of the authors of the study. (utmb.edu)
For example, Lassa fever is limited to rural areas of West Africa where rats and mice carry the virus. (medlineplus.gov)
Lassa fever is endemic to West Africa, where Mastomys natalensis rodents, a primary animal reservoir of Lassa virus, are common. (nih.gov)
Lassa fever is commonly found in parts of West Africa including Sierra Leone, Liberia, and Nigeria. (nih.gov)
BackgroundLassa fever is a viral haemorrhagic fever endemic in parts of west Africa. (ox.ac.uk)
Lassa fever is endemic in west Africa, where it probably kills several thousand people each year. (academicoo.com)
The reservoir of Lassa virus is the multimammate mouse (Mastomys natalensis), a highly commensal species in West Africa. (socialscienceinaction.org)

Lassa fever is known to be endemic in Guinea, Liberia, Nigeria and Sierra Leone, but probably exists in other West African countries as well. (who.int)
Based on serologic data, indigenous people in endemic areas have a very high rate of infection-much higher than their rate of hospitalization for Lassa fever-suggesting that many infections are mild and self-limited. (msdmanuals.com)
Endemic to Nigeria, Lassa fever belongs to the same family as the Ebola and Marburg viruses, but is much less deadly. (channelstv.com)
Lassa Fever (LF) is a haemorrhagic virus endemic in Western Africa. (nursinganswers.net)
Lassa fever is endemic in Nigeria and the annual peak of Lassa fever cases is typically observed during the dry season (December-April). (ritaduba.com)
While Lassa fever is endemic in Nigeria and the country has developed an increased capacity for the prevention and control of Lassa fever outbreaks, including strengthened surveillance, diagnostic and treatment capacity, several factors contribute to the current elevated risk level. (ritaduba.com)
Lassa fever is endemic in several west African countries. (netecweb.org)

By 18 March, 3675 contacts of the 376 confirmed Lassa fever cases in Nigeria had been identified and more than three-quarters had completed their 21 days of monitoring. (who.int)
Confirmed Lassa fever cases in Nigeria spiked over 2017 to 2018. (nih.gov)
In Nigeria, from 3 to 30 January 2022, 211 laboratory confirmed Lassa fever cases including 40 deaths (case fatality ratio: 19%) have been cumulatively reported in 14 of the 36 Nigerian states and the Federal Capital Territory across the country (Figure 1). (ritaduba.com)
Weekly number of reported confirmed Lassa Fever cases and deaths in Nigeria during the epidemiological weeks one (commencing 2 January) through four (commencing 23 January) in 2022. (ritaduba.com)
The NCDC noted that 72 per cent of all confirmed Lassa fever cases were reported from Ondo , Edo and Bauchi states while 28 per cent were reported from two states with confirmed Lassa fever cases. (naijablitznews.com)
A statement issued by the Director General of the NCDC, Dr. Ifedayo Adetifa, yesterday, stated that the measure became necessary given the increase in the number of confirmed Lassa fever cases across the country and a joint risk assessment with partners and sister agencies. (africahealthtimes.com)

When caring for patients with Lassa fever, further transmission of the disease through person-to-person contact or nosocomial routes can be avoided by taking preventive precautions against contact with patient secretions (called VHF isolation precautions or barrier nursing methods). (cdc.gov)
Identify the parameters for clinical management of patients with Lassa fever. (netecweb.org)
Describe my role, responsibility, and scope of practice as a team member in diagnosing and treating patients with Lassa fever. (netecweb.org)

About 15 to 20 percent of people hospitalized with Lassa fever die from the disease, but only 1 percent of all Lassa virus infections result in death, according to the U.S. Centers for Disease Control and Prevention. (nih.gov)

The NCDC reported that from January 1 to April 9, 2023, a total of 869 confirmed cases of Lassa fever had been reported from 26 states and 101 local government units. (potpourrinews.com)
This information was conveyed through the NCDC's official website on Tuesday, as part of its Lassa Fever Situation Report for Week 37 (September 11 - 17, 2023). (com.ng)
Tragically, in 2023, 49 healthcare workers across the country contracted Lassa fever. (com.ng)
The Nigeria Centre for Disease Control and Prevention made this known in its Lassa fever situation report for week nine spanning January to March 5, 2023. (naijablitznews.com)

Primary transmission of the Lassa virus from its host to humans can be prevented by avoiding contact with Mastomys rodents, especially in the geographic regions where outbreaks occur. (cdc.gov)
The Lassa virus is carried by rodents and transmitted to humans through contact with urine or droppings of infected rodents. (vanguardngr.com)
The fever is caused by Lassa virus, which is normally transmitted to humans through contact with food or household items contaminated with urine or feces from infected rodents. (nih.gov)
It also stressed the importance of preventing Lassa fever through measures such as avoiding contact with rodents and their excreta, maintaining good personal hygiene, and taking precautions when caring for infected individuals. (com.ng)
Lassa fever is an acute viral hemorrhagic illness transmitted to humans through contact with food or household items contaminated by rodents infected with Lassa fever virus. (africahealthtimes.com)

Research is presently under way to develop a vaccine for Lassa fever. (cdc.gov)
There is no approved vaccine for Lassa fever, whose symptoms are similar to Ebola. (courthousenews.com)

It no doubt will serve as further support of the value of continued investment in immunotherapeutics research for the treatment of Lassa fever in humans. (utmb.edu)
Background Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. (ox.ac.uk)

UK Responds to Lassa Fever Outbreak in Nigeria - Medscape - Mar 06, 2018. (medscape.com)
In 2018, Nigeria experienced its largest-ever Lassa fever outbreak, with 514 confirmed cases and 134 deaths from Jan. 1 through Sept. 30, according to the Nigeria Centre for Disease Control . (nih.gov)
A surge in Lassa fever cases in Nigeria in 2018 does not appear to be linked to a single virus strain or increased human-to-human transmission, according to a genomic analysis published in The New England Journal of Medicine . (nih.gov)
The Nigeria Centre for Disease Control (NCDC) reported an unusually large increase in Lassa fever cases in 2018, with 523 laboratory-confirmed cases and 135 deaths from January 1 through October 7. (nih.gov)
Public health officials were concerned that the Lassa fever outbreak in Nigeria in 2018 might be driven by a previously unknown factor, such as a new or more virulent Lassa virus strain, according to the authors. (nih.gov)
The authors analyzed Lassa virus genomes of 129 patients from the 2017-2018 outbreak and from 91 patients from the 2015-2017 seasons. (nih.gov)
They discovered that Lassa genomes from 2018 were drawn from a diverse range of viruses previously observed in Nigeria rather than from a single dominant strain. (nih.gov)
Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018. (nih.gov)
The Lassa fever outbreak in Ondo State in 2018 recorded high morbidity and mortality . (bvsalud.org)
We used univariable and multivariable logistic regression models to investigate an association between baseline characteristics and mortality at day 30.FindingsBetween April 5, 2018, and March 15, 2020, 534 patients with confirmed Lassa fever were admitted to hospital, of whom 510 (96%) gave consent and were included in the analysis. (ox.ac.uk)

To help mitigate the outbreak of Lassa fever and other diseases, the Federal Capital Territory Administration (FCTA) through the Abuja Markets Management Limited (AMML) has commenced fumigation exercise in all its markets in the Territory. (peoplesdailyng.com)
Also speaking, Ismaila Haruna Dankogi, of Abuja Environmental Protection Board (AEPB), maintained that residents of the FCT have no need to worry about any outbreak of Lassa fever, as the board has always been involve in the routine cleaning markets and other places. (peoplesdailyng.com)
An outbreak of Lassa fever has been reported in Ondo State. (xclusive.ng)

Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other viral haemorrhagic fevers. (who.int)
Other conditions that may present similarly include Ebola, malaria, typhoid fever, and yellow fever. (wikipedia.org)
Polio, Lassa and Yellow fever: Where is the political will? (kff.org)
The most prominent and reoccurring have been polio, Lassa fever, and yellow fever. (kff.org)
The findings suggest that viral infections, such as outbreaks of Ebola, yellow fever, and Lassa fever, may have played an important role over centuries in driving genetic differences on the African continent. (nih.gov)
These include the Ebola and Marburg, Lassa fever, and yellow fever viruses. (medlineplus.gov)

According to the Nigeria Centre for Disease Control, there have been 1,081 suspected cases of Lassa fever and 90 deaths between the 1st January and the 25th February this year. (medscape.com)
So far, the Nigeria Centre for Disease Control has confirmed thatlassa fever has hit 21 states in Nigeria with a total of 106 deaths and 651 persons infected. (com.ng)
In contrast, noticeably less Lassa fever cases with less geographical spread were reported for the same period (epidemiological weeks 1- 4) in 2021 (54 confirmed cases, including 12 deaths, from 8 States). (ritaduba.com)
According to the Nigeria Centre for Disease Control and Prevention, there have been 151 Lassa fever deaths in Nigeria so far this year, up from 148 the year before. (potpourrinews.com)
The Federal Government has put the number of reported cases of Lassa Fever outbreak in eight states at 76 with 35 deaths already recorded and 14 cases confirmed by laboratories. (tvcentertainment.tv)
Three people have died from Lassa fever and 13 others afflicted in five states across the country in the last two weeks.According to latest figures from the Nigeria Centre for Disease Control (NCDC) published yesterday, the three new deaths occurred, one each in Plateau, Edo and Gombe states. (otowngist.com)
Dr Kunden Deyin, the Plateau Commissioner for Health says the state has recorded 28 new cases of Lassa fever with 10 deaths. (dailyadvent.com)

Ribavirin is effective treatment for Lassa fever is given early in the course of clinical illness. (who.int)

The overall Lassa virus infection case-fatality rate is about 1 percent, according to the World Health Organization (WHO), but that rate rises to 15 percent for patients hospitalized with severe cases of Lassa fever. (nih.gov)
The Lassa virus, a member of the arenavirus family of viruses, is said to be the cause of Lassa fever, an acute viral hemorrhagic sickness, according to the World Health Organization. (potpourrinews.com)

Just last week, the Centre for Diseases Control, CDC, confirmed a diagnosis of Lassa fever in a patient admitted to a hospital in Minnesota. (vanguardngr.com)
Nigeria has set up an emergency response centre to contain rising cases of Lassa fever after 26 people were killed in the past three weeks, the country's disease control agency said. (channelstv.com)
The Nigeria Centre for Disease Control (NCDC) said on Wednesday it had activated the national Lassa fever Emergency Operations Centre (EOC) in response to the outbreak in some parts of the country. (channelstv.com)
The Nigeria Centre for Disease Control (NCDC) said this in its latest Lassa fever situation report for week 29, which showed that there were 857 confirmed cases of the disease in the country. (dailytrust.com)
any persons suspecting lassa should immediately report at the health centre near you. (com.ng)
We aimed to document baseline characteristics and outcomes for patients hospitalised with Lassa fever in Nigeria.MethodsWe did a prospective cohort study (LASCOPE) at the Federal Medical Centre in Owo, Nigeria. (ox.ac.uk)
All pleas and entreaties to Federal Ministry of Health, the Nigeria Centre for Disease Control and Prevention, the National Primary Health Care Development Agency and other federal agencies to come and support us to save our people from Lassa Fever, have been ignored. (gbetutv.com)
The Nigeria Centre for Disease Control and Prevention (NCDC) has reported a total of 1,068 Lassa fever cases spread across 112 local government areas within 28 states of the federation. (com.ng)
The agency emphasized that the National Lassa Fever Multi-partner, Multi-sectoral Emergency Operations Centre has been activated to oversee response activities at all levels. (com.ng)

About 80% of human Lassa fever infections are mild or asymptomatic. (who.int)
About 1% of all Lassa virus infections result in death. (wikipedia.org)
This creates a real challenge for therapeutic developers as it raises the question of whether a single drug could be used to treat all Lassa virus infections. (utmb.edu)
clinical studies on filariasis and clinical studies on HIV/TB co-infections, and more recently Ebola Virus Disease, Crimean Congo Hemorrhagic Fever Virus, and COVID-19. (nih.gov)
It is just a coincidence that it is happening now when there is a loud cry about sensitization on Lassa fever and coronavirus infections. (peoplesdailyng.com)
Given that 90-95% of human infections are due to indirect exposure (through food or household items contaminated by infected rats' excreta) or direct contact with infected Mastomys rats, the very high density and high circulation of Lassa fever virus in the rat population poses a risk for further human infection during the dry season. (ritaduba.com)
Approximately 80% of Lassa virus infections in humans are either asymptomatic or mild, however, infection in the remaining 20% manifests as a febrile illness of variable severity associated with multiple organ dysfunctions with or without haemorrhage. (ritaduba.com)

These symptoms can be difficult to distinguish from other haemorrhagic fevers (such as Ebola) or other febrile diseases (Malaria). (nursinganswers.net)

The researchers reported their findings to the NCDC and other public health officials in real time to help respond to the high number of Lassa fever cases in Nigeria. (nih.gov)
The states are Edo -20, Ondo-eight, Ebonyi-three, Kogi -three, Bauchi-one and Adamawa-one).To further address the situation, the NCDC has planned a Lassa fever international conference for January 16 to 17, 2019 and Lassa fever national multi-partner, multi-agency Technical Working Group (TWG) to coordinate response activities at all levels. (otowngist.com)

The International Atomic Energy Agency convened a workshop last week to explore how nuclear techniques backed by the IAEA's Zoonotic Disease Integrated Action (ZODIAC) initiative could be used to avoid outbreaks of monkeypox and Lassa fever. (ans.org)
These factors combined warrant the need for further improvement and support of the country's capacity to detect and respond to Lassa fever outbreaks. (ritaduba.com)

Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus, a member of the arenavirus family of viruses. (who.int)

A fatal case of Lassa fever in London, January 2009. (nih.gov)

It feels like it's not the first time I heard of Lassa fever then again it felt like it. (favoritephysician.org)

The victim, who was returning to the United States from a West African country, exhibited symptoms of fever and confusion and blood samples submitted to CDC tested positive for Lassa fever. (vanguardngr.com)
In this observational study, we analysed left-over blood samples from patients who tested positive for Lassa fever at Irrua Specialist Teaching Hospital, Nigeria, between January, 2014, and April, 2017. (netecweb.org)
Of 554 patients who tested positive for Lassa fever during the study period, 201 (131 in the primary dataset and 70 in the secondary dataset) were included in the biomarker analysis, of whom 74 (49 in the primary dataset and 25 in the secondary dataset) had died and 127 (82 in the primary dataset and 45 in the secondary dataset) had survived. (netecweb.org)

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden. (lassafever.info)

Hilary Bower, who will be leading the UK team, says in a statement: "There is still much to learn about what drives the transmission of Lassa fever and the different ways it can affect people. (medscape.com)
Person-to-person transmission of Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. (who.int)

These surface proteins prompt an immune response against both Lassa and rabies viruses. (nih.gov)
The Lassa virus is a member of the Arenaviridae family of viruses. (wikipedia.org)
A recent study that identified the top 50 agents with pandemic potential, Lassa fever was ranked first among known viruses regarded as a threat for zoonotic spillover. (utmb.edu)
Using nuclear science and technology, the IAEA will work together with ZODIAC national laboratories in Africa, Asia, Europe, and Latin America to adjust the diagnostic algorithms for monkeypox and Lassa fever to improve the global understanding of how the viruses spread from species to species. (ans.org)
These scientific teams are now developing a research program to screen for and study other hemorrhagic fever viruses in the country. (nih.gov)
This concern led a team of researchers, including members of the NIH Common Fund-supported Human Heredity and Health in Africa ( H3Africa (link is external) ) program, to conduct a genetic analysis of viruses in samples collected from Lassa-infected patients. (nih.gov)
It is part of the Arenaviridae family along with other viruses which cause haemorrhagic fever such as Machupa virus [2] . (nursinganswers.net)

Lassa fever is an animal-borne, or zoonotic, acute viral illness spread by the common African rat. (cdc.gov)
Although Lassa fever is often a mild illness, some people experience serious symptoms, such as hemorrhage (severe bleeding) and shock. (nih.gov)
Illness begins insidiously with a nonspecific syndrome of fever, weakness, malaise, and joint and/or lumbar pain. (medscape.com)
Lassa virus is a single stranded RNA virus causing Lassa Fever (LF), an acute haemorrhagic illness [1] . (nursinganswers.net)
Lassa fever is an acute viral hemorrhagic illness of 1-4 weeks duration. (com.ng)
Lassa Fever is a zoonotic hemorrhagic illness predominant in areas across Nigeria, Sierra Leone, Guinea, Liberia, and southern Mali. (socialscienceinaction.org)

The Lassa virus, shown here, causes Lassa fever. (cdc.gov)
Findings are also not ruling out the possible source of infection from consumption of meat infected with the Lassa virus which causes Lassa fever, another severe viral disease that produces hemorrhagic symptoms similar to that seen in infected persons. (vanguardngr.com)

Symptoms of lassa fever include: gradual onset of persistent fever( that does not respond to treatment with panadol or antibiotics), general weakness and feeling unwell. (com.ng)
water /or use of hand sanitisers when appropriate and visit the nearest health facility if you notice any of the signs and symptoms of Lassa fever as mentioned earlier, and avoid self-medication. (africahealthtimes.com)

The clinical picture of the haemorrhagic disease, which is in the class of Marburg haemorrhagic fever- is nightmarish. (vanguardngr.com)

The virus may also be spread between humans through direct contact with the blood, urine, feces, or other bodily secretions of someone infected with Lassa fever. (medscape.com)
Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. (who.int)
The Lassa virus is transmitted to humans via contact with food or household items contaminated with rodent urine or faeces. (who.int)
This virus has both a large and a small genome section, with four lineages identified to date: Josiah (Sierra Leone), GA391 (Nigeria), LP (Nigeria) and strain AV. Lassa virus commonly spreads to humans from other animals, specifically the Natal multimammate mouse or African rat, also called the Natal multimammate rat (Mastomys natalensis). (wikipedia.org)
Lassa virus is transmitted to man by infected multi-mammate rats and humans become infected from direct contact with the urine and faeces of the rat carrying the virus. (dailytrust.com)
Over three quarters 2, 537 (84.8%) of respondents were aware of Lassa fever of which 2, 363 (93.1%) knew that multimammate rat transmits the disease to humans . (bvsalud.org)
Lassa fever is a viral haemorrhagic fever that is primarily transmitted to humans via contact with food or household items contaminated with urine or faeces from Mastomys rats. (ritaduba.com)
As aforementioned, the peak of Lassa fever cases in humans typically occurs in the dry season (December-April) and follows the reproduction cycle of the Mastomys rats in the wet season (May - November). (ritaduba.com)
The most common way for humans to contract the Lassa virus is through contact with food or household items that have been tainted by the urine or feces of infected Mastomys rats. (potpourrinews.com)
Humans usually become infected with the Lassa virus through exposure to food or household items contaminated with the urine or faeces of infected Mastomys rats. (naijablitznews.com)
In late February/early March 2016 in Benin, (foreground) Carine, a student at the district school in Tchaourou, smiles as she holds up her slate with the correct answer Lassa Fever to the question posed by her teacher: What disease is making people in our town sick these days and is being transmitted from rats to humans and from person to person? (socialscienceinaction.org)

The incubation period for Lassa fever ranges from 2 to 21 days. (who.int)
The incubation period for Lassa fever is 5 to 16 days. (msdmanuals.com)
After an incubation period of 8-13 days, a nonspecific syndrome of fever, weakness, malaise, joint and/or lumbar pain, nausea and vomiting, and cough may begin. (medscape.com)
LF has an incubation period between 6-212 days and, for the 20% who do experience symptoms, the early symptoms increase in intensity gradually starting from a fever, general malaise and other non-specific symptoms. (nursinganswers.net)

Lassa fever is named after the town in Nigeria where the first cases occurred. (cdc.gov)
Lassa Fever, From 2005 through 2008, 10 cases bers were involved in the outbreak. (cdc.gov)
Cases 7 to 10 occurred in Abuja epidemiologic situation is less clear rus-specifi c IgM during his convales- and Jos from December 2007 through because no surveillance system is in cent phase indicates that he had Lassa March 2008. (cdc.gov)
Most cases manifest as mild fever, headache, and malaise. (medscape.com)
This prompted the research team to analyze Lassa virus genomes from patient samples to determine if genomic data signatures could explain the surge in cases. (nih.gov)
of course the list will not be exhaustive as new cases of lassa fever are diagnosed everyday in the various states across the federation coupled with the fact that some cases are misdiagnosed or not reported. (com.ng)
These include an increase in the number of confirmed cases compared to previous epidemic seasons, gaps in surveillance and varying degrees of subnational response capacity, delays in sample shipment for laboratory testing, a decrease of case management capacity due to conversion of dedicated Lassa fever facilities into COVID-19 health-care facilities and suboptimal IPC procedures. (ritaduba.com)
The Commissioner for Health in Plateau, Dr Ndam Lar, on Tuesday, said that the state had recorded seven confirmed cases of Lassa fever from November 2019 till date. (com.ng)
The increasing number of Lassa Fever cases in the State as well as measures to contain the spread of the deadly disease were deliberated. (gbetutv.com)
Lassa fever has continued to spread in Nigeria with 676 confirmed cases recorded across 89 local government areas in 22 states in the country. (naijablitznews.com)
Deyin told the News Agency of Nigeria (NAN) in Jos on Thursday that 64 cases were taken to the laboratory for confirmation out of which 28 were confirmed to be Lassa fever. (dailyadvent.com)
Lassa Fever, a viral disease that can be fatal in severe cases, is transmitted through contact with rats infected with the virus and through person-to-person contact. (socialscienceinaction.org)
UK patient dies as more cases of Lassa fever reported. (euronews.com)

People contract Lassa virus through contact with infected Mastomys rats and through exposure to an infected person's bodily fluids. (nih.gov)
Neighbouring countries are also at risk, as the animal vector for the Lassa virus, the "multimammate rat" (Mastomys natalensis) is distributed throughout the region. (dailytrust.com)

The newly published findings show that LASSARAB, when administered with GLA-SE adjuvant (an immune response-stimulating protein), elicits antibodies against Lassa virus and rabies virus in mouse and guinea pig models. (nih.gov)
The vaccine also protected guinea pigs from Lassa fever after being exposed to the virus 58 days after vaccination. (nih.gov)
A new vaccine showed preclinical promise at effectively protecting people from Lassa fever and rabies in a study involving mice and guinea pigs. (medworm.com)
Authorities in Guinea announced the first death from Lassa fever in more than two decades Thursday, heightening anxiety about another hemorrhagic fever in the West African country where an Ebola epidemic first emerged. (courthousenews.com)
This resource reviews the present literature on treatment and pathogenesis of Lassa fever and outlines priorities for future research in the field made possible by the improved research capacity of the Mano River Union countries of Sierra Leone, Liberia, and Guinea, Lassa fever network. (lassafever.info)
Lassa fever, a viral hemorrhagic fever caused by the Lassa virus, primarily afflicts West African countries such as Sierra Leone, Liberia, Guinea, and Nigeria. (com.ng)
The Enable Lassa Fever Research programme, funded by the Coalition for Epidemic Preparedness Innovations (CEPI), was launched in 2019 to estimate the incidence of infection and disease due to Lassa Fever Virus in five West African countries (Benin, Guinea, Liberia, Nigeria and Sierra Leone). (p-95.com)

The Ondo State government, says a total of 34 persons have died of Lassa Fever in the state from January to date. (punchng.com)

Lassa virus is a single-stranded RNA virus in the Arenaviridae family. (msdmanuals.com)

Lassa fever is a zoonotic disease associated with high morbidity and mortality, and it has both economic and health security implications. (dailytrust.com)

Lagos has been the worst hit of the recent lassa fever outbreak in 2017. (com.ng)

Her clinical features (94-97% and 90-94% identity in the Since then, laboratory capacity at the were compatible with Lassa fever, but GP and L genes, respectively). (cdc.gov)
Conclusions This project represents the first step towards delineating the clinical development pathway for new Lassa fever therapeutics, following a period of 40 years without advancement. (ox.ac.uk)
Describe at least two methods for identifying a patient with Lassa fever infection in the clinical setting. (netecweb.org)

Further, educating people in high-risk areas about ways to decrease rodent populations in their homes will aid in the control and prevention of Lassa fever. (cdc.gov)
Sleeping under mosquito bed nets and intake of herbal concoction were the principal mode of prevention of Lassa fever reported by respondents. (lassafever.info)

Lassa fever is a viral haemorrhagic fever transmitted by rats. (dailytrust.com)
We should not allow rats wipe out the human race through the lassa fever virus they harbour. (com.ng)

This means that people were still getting Lassa virus by contact with rodent droppings. (nih.gov)

NIH/National Institute of Allergy and Infectious Diseases) A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications. (medworm.com)

A combination of pharyngitis, pain behind the sternum, presence of excess protein in the urine and fever can indicate Lassa fever with higher specificity. (wikipedia.org)
Lassa fever is spread by contact with rat faeces urine or the bodily fluids of an infected person. (channelstv.com)

Fever, general weakness and malaise are usually the first symptoms to appear in symptomatic patients. (who.int)

In some areas of Sierra Leone and Liberia, about 10-16% of people admitted to hospitals annually have Lassa fever. (cdc.gov)
None of the patient's contacts in Liberia became sick or tested positive for Lassa," the statement said. (courthousenews.com)
In some areas of Sierra Leone and Liberia, it is known that 10%-16% of people admitted to hospitals have Lassa fever, which indicates the serious impact of the disease on the population of this region. (imageenvision.com)
A 57-year-old woman presents to a clinic in Liberia for high fevers, nausea, and vomiting. (medbullets.com)

Both monkeypox and Lassa fever have been reported in Africa since the early 1970s. (ans.org)

The virus responsible was identified in 1969 after two missionary nurses died from the disease in the Nigerian town of Lassa. (medscape.com)
Though first described in the 1950s, the virus causing Lassa disease was not identified until 1969. (who.int)
The virus was first described in 1969 from a case in the town of Lassa, in Borno State, Nigeria. (wikipedia.org)
The virus takes its name from the town of Lassa in northern Nigeria, where it was first identified in 1969. (channelstv.com)
It has been known since the 1950s, but the virus was not identified until 1969 when two missionary nurses died from it in the town of Lassa in Nigeria. (dailytrust.com)

To determine risk of Lassa fever in households in Sierra Leonean refugee camps, this paper analysed the spatial relationships between households with a Lassa case and focal locations of potential rodent habitats. (lassafever.info)
Quality and hygiene factors of households were assessed to determine possible risk factors for household rodent infestation and occurrence of Lassa fever. (lassafever.info)

After a few days' respite, a second phase of aseptic meningitis may follow, with fever, severe headache, and neck stiffness. (medscape.com)

Organisms9

Diseases10

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Named Groups1

Health Care2

Geographicals5

Infected with Lassa virus7

Hemorrhagic fevers4

West Africa12

Endemic7

Confirmed Lassa fever cases6

Patients with Lassa fever3

Centers for Diseas1

20234

Rodents5

Vaccine for Lassa fever2

Treatment of Lassa fever2

201810

Outbreak of Lassa fever3

Yellow fever6

Deaths7

Effective treatment for Lassa fever1

World Health Organ2

Centre9

Infections7

Difficult to distinguish1

NCDC2

Outbreaks2

Caused by Lassa virus1

Case of Lassa fever1

Heard of Lassa fever1

Positive for Lassa fever3

Knowledge on Lassa fever1

Transmission of Lassa fever2

Viruses7

Illness6

Causes Lassa fever2

Symptoms of lassa fever2

Marburg1

Humans11

Incubation period4

Cases13

Mastomys2

Guinea7

Ondo State1

Arenaviridae1

Zoonotic1

20171

Clinical3

Prevention2

Rats2

Contact with rodent1

Diseases1

Urine2

Malaise1

Liberia4

Africa1

19695

Rodent2

Severe1