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  • inflammatory
  • This Langerhans cell-targeted immune escape mechanism seems to be conserved among different HPV genotypes enabling these viruses to remain undetected in the absence of other inflammatory events. (wikipedia.org)
  • Pimecrolimus also prevents the release of inflammatory cytokines and mediators from mast cells. (wikipedia.org)
  • citation needed] Pimecrolimus, like tacrolimus, belongs to the ascomycin class of macrolactam immunosuppressives, acting by the inhibition of T-cell activation by the calcineurin pathway and inhibition of the release of numerous inflammatory cytokines, thereby preventing the cascade of immune and inflammatory signals. (wikipedia.org)
  • Crosslinking of the FcεRI via IgE-antigen complexes leads to degranulation of mast cells or basophils and release of inflammatory mediators. (wikipedia.org)
  • inhibits
  • citation needed] Thus pimecrolimus inhibits T-cell activation by inhibiting the synthesis and release of cytokines from T-cells. (wikipedia.org)
  • cytokines
  • The symptoms of histiocytosis are caused by substances called cytokines and prostaglandins, which are normally produced by histiocytes and act as messengers between cells. (encyclopedia.com)
  • These cells secrete cytokines (a non-antibody protein that generates an immune response on contact with specific antigens), and are an essential part of the immune system. (wikipedia.org)
  • Spontaneous regression is common in these tumors, and it is mediated by infiltration of CD8-expressing T cells followed by expression of Type 1 T helper cell cytokines (such as Interferon-gamma) and recruitment of antitumour effector cells[disambiguation needed]. (wikipedia.org)
  • histiocyte
  • A histiocyte is an animal cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system). (wikipedia.org)
  • However, the term histiocyte has been used for multiple purposes in the past, and some cells called "histocytes" do not appear to derive from monocytic-macrophage lines. (wikipedia.org)