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  • gene
  • Fifteen clones obtained from a cDNA library of mock-infected cells and one from a library prepared at 2 h postinfection (p.i.) were found to comprise one distinct gene, which was identified as the Bombyx homolog (bLaminin) of Drosophila laminin β1. (deepdyve.com)
  • Deletion of the IS 1548 sequence between scpB and lmb genes in a CC19 serotype III GBS strain substantially reduced the transcription of lmb gene (13.5-fold), the binding ability to laminin (6.2-fold), and the expression of Lmb protein (5.0-fold). (pubmedcentralcanada.ca)
  • Characterization and localized expression of the laminin binding protein/p40 (LBP/p40) gene during sea urchin development. (semanticscholar.org)
  • p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors. (uniprot.org)
  • Here we study the regulatory elements that control basal and cytokine-activated transcriptional expression of the LAMC2 gene, which encodes the laminin γ2 chain. (biochemj.org)
  • This gene provides instructions for making a part (subunit) of certain members of a protein family called laminins. (nih.gov)
  • Most LAMA2 gene mutations that cause the severe, early-onset form of LAMA2 -related muscular dystrophy result in the absence of functional laminin alpha-2 subunit. (nih.gov)
  • Most LAMA2 gene mutations that cause early-onset LAMA2 -related muscular dystrophy result in the absence of functional laminin alpha-2 subunit. (nih.gov)
  • Lama2
  • Mice with a homozygous mutation in Lama2 ( dy2J mice) express a nonpolymerizing form of laminin-211 (Lm211) and are a model for ambulatory-type Lmα2-deficient muscular dystrophy. (jci.org)
  • Mutations that cause late-onset LAMA2 -related muscular dystrophy usually result in a reduction (deficiency) of functional laminin alpha-2 subunit. (nih.gov)
  • mutations
  • Laminin LN domain mutations linked to several of the Lmα2-deficient muscular dystrophies are predicted to compromise polymerization. (jci.org)
  • Mutations that cause the milder, later-onset form usually result in a reduction (deficiency) of functional laminin alpha-2 subunit. (nih.gov)
  • expression
  • The data herein support the hypothesis that engineered expression of αLNNd can overcome polymerization deficits to increase laminin, stabilize BM structure, and substantially ameliorate muscular dystrophy. (jci.org)
  • C ) αLNNd protein expression was probed by immunoblotting of extracts from 3- and 8-week-old triceps (Tr) and tibialis anterior (TA) (goat anti-Lmα1-LN Ab). (jci.org)
  • Now we've gone one step further and are working together to combine BioLamina's expertise in recombinant laminin expression with Corning's extensive line of vessels and proprietary surface coating technologies. (corning.com)
  • diagrams
  • Laminin molecules are often portrayed as cross shaped, with straight limbs, but this form really only occurs in formalized diagrams. (ibosocial.com)
  • cell
  • Witness Laminin right HERE http://stg.do/Ryvb ============== The Cross Of Laminin ============== What the "Cross" represents in biological terms is the cell structure of Laminin in the human body. (ibosocial.com)
  • This implies that the anisotropy of laminin stripes is an effective chemical stimulus for cell recruiting and alignment. (scriba-nanotec.com)
  • Using an affinity chromatography approach, we have isolated a BCG collagen-binding protein corresponding to the previously described mycobacterial laminin-binding histone-like protein (LBP/Hlp), a highly conserved protein associated with the mycobacterial cell wall. (fiocruz.br)
  • Corning has partnered with BioLamina for the supply of recombinant human laminin 521 (rLaminin-521), a next generation surface that enables feeder-free, single cell passaging of pluripotent stem cells (PSCs) without ROCK-inhibitor. (corning.com)
  • There, the laminins help regulate cell growth, cell movement (motility), and the attachment of cells to one another (adhesion). (nih.gov)
  • significance
  • Objective To investigate the changes of serum contents of laminin (LN) in preoperative and postoperative patients with colorectal cancer and its value in diagnosis and prognosis of the cancer,and to evaluate the clinical significance of serum LN in neoplastic relapse and metastasis as compared with CEA and CA 242. (cnki.com.cn)
  • synthesis
  • Firstly, SVZ cells were analyzed following incubation of BEC with the protein synthesis inhibitor cycloheximide (CHX) prior to coculture, a treatment expected to decrease membrane proteins. (frontiersin.org)
  • fragment
  • This short promoter fragment contains two activator protein 1 (AP-1) elements and the 5ʹ-most of these is a composite AP-1/Sp1 element. (biochemj.org)
  • form
  • Several high-profile ministers have been discussing and promoting Laminin due to this unusual form. (ibosocial.com)
  • These are the sheets of protein that form the substrate (a substance acted upon by an enzyme) of all internal organs. (slideplayer.com)