• L-lactate dehydrogenases are metabolic enzymes which catalyse the conversion of L-lactate to pyruvate, the last step in anaerobic glycolysis [ PMID: 11276087 ]. (ebi.ac.uk)
  • In analogous clinical scenarios presenting with disrupted mitochondrial function (e.g., mitochondrial disorders such as Leigh syndrome or MELAS [ 14 , 15 ]), lactate (lac), the by-product of anaerobic glycolysis, is elevated in part as compensation for aerobic metabolic impairment [ 16 - 18 ]. (hindawi.com)
  • Although lactate production does not contribute to acidosis and lactate itself does not appear to cause fatigue, blood lactate accumulation does indicate that the body is relying on substantial contributions from anaerobic glycolysis to meet exercising energy requirements. (humankinetics.com)
  • There has therefore existed, for a substantial period of time, the need for a simple testing mechanism for the determination of the concentration of serum lactate dehydrogenase in body fluids, especially the blood, which long-felt need is satisfied by the instant invention more fully discussed hereinbelow. (freepatentsonline.com)
  • Additionally, we review the evolving role of lactate in sepsis care. (nih.gov)
  • Though lactate production does not result in acidosis and has a questionable role in causing fatigue, the accumulation of lactate in the blood indicates that maximal sustainable rates of exercise and ATP production are close at hand (Morris and Shafer 2010). (humankinetics.com)
  • My test means is useful for the qualitative detection and quantitative determination of lactate dehydrogenase in sera wherein the test means comprises a reagent composition incorporated within a bibulous carrier. (freepatentsonline.com)
  • Zinc lactate dihydrate is produced by complete neutralisation of lactic acid with a high purity zinc source and subsequent crystallisation. (jungbunzlauer.com)
  • Due to its antimicrobial properties and its ability to reduce or inhibit the formation of dental plaque and tartar, zinc lactate is mainly used in dental care products like toothpaste or mouthwash. (jungbunzlauer.com)
  • Zinc lactate is supplied as a white to almost white fine powder. (jungbunzlauer.com)
  • Zinc lactate is currently not listed in European or US Pharmacopeias. (jungbunzlauer.com)
  • Jungbunzlauer Zinc lactate specification is reflecting the requirements for food and oral care usages. (jungbunzlauer.com)
  • In Europe, zinc lactate is on the positive list of Regulation (EC) No. 1925/2006 on food fortification. (jungbunzlauer.com)
  • High-intensity workouts improve the heart's capacity to deliver oxygen and the muscles' ability to use that oxygen, as well as the body's ability to clear lactate from the blood. (runnersworld.com)
  • Lactate is then converted to pyruvate, which activates HIF-1α and NF-κB/IL-8 signaling. (jci.org)
  • Alternately, these data support previous claims that lactate is converted to pyruvate within the mitochondrial intermembrane space with the pyruvate subsequently taken into the mitochondrial matrix where it enters the TCA cycle and is ultimately oxidized. (sigmaaldrich.com)
  • Measurement of released lactate dehydrogenase (LDH) activity, a commonly used marker of lethal cell injury in both in vitro and in vivo screenings, has been used to assess the cytotoxicity of nanoparticles (NPs), chemical compounds, and environmental factors. (nih.gov)
  • In a platform presentation at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), he noted that measurement of lactate in CSF is "simple and cheap," and results can be had from clinical labs in many hospitals within a few minutes. (medpagetoday.com)
  • Measurement of plasma D-lactate at 24h and 48h after ANP induction using ab83429. (abcam.com)
  • The body's utilization of lactate can be increased with training. (news-medical.net)
  • Lactate is produced in excess by muscle cells, red blood cells, brain, and other tissues when there is insufficient oxygen at the cellular level or when the primary way of producing energy in the body's cells is disrupted. (labcorp.com)
  • Despite the similarity in name, sodium lactate is not chemically similar to lactose (milk sugar), so need not be restricted by those with lactose intolerance . (wikipedia.org)
  • Moreover, although the lactic-acid starter culture to ferment corn or beets may contain milk, sodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy. (wikipedia.org)
  • In the early 20th century, oral administration of calcium lactate dissolved in water (but not in milk or tablets) was found to be effective in prevention of tetany in humans and dogs with parathyroid insufficiency or who underwent parathyroidectomy. (wikipedia.org)
  • i wanna know if starting to lactate at 12 weeks pregnate is normal it wasn't the milk. (circleofmoms.com)
  • SINCE it was first unequivocally shown that the milk yield of lactating cows could be increased by feeding dried thyroid gland 1 or injecting thyroxine 2,3 , many experiments (see Reineke 4 for review of some of them) have been carried out on the practical use of thyroid-active substances for increasing the milk yield of cows over limited periods of time. (nature.com)
  • The traditional kitchen spice, Fenugreek seeds contain an active ingredient called diosgenin that increase milk production in lactating mothers. (medindia.net)
  • The active ingredient in fenugreek seeds called diosgenin increases milk production in lactating mothers. (medindia.net)
  • Lactating is a natural progression and with hormones, my trusty breast pump and hours of beautifully thrilling stimulation and nipple play I am showing signs of lactation, with the milk ducts opening and leaking fluid. (experienceproject.com)
  • i too have been lactating for almost a year now- you are right it is very exciting when you see milk coming from your breasts. (experienceproject.com)
  • As food additive, the adding amount of Calcium Lactate should be in accordance with the requirements of GB14880-94 and GB2760: 12-24g in cereal and cereal product, 3-6g in beverage and milk beverage, 23-46 in nurseling food. (fuzing.com)
  • Legislation expected to pass the House on Tuesday would give lactating moms access to private spaces in federal buildings for pumping breast milk. (usatoday.com)