Secretion of lacrimalArterySalivary gland functionParasympathetic and sympatheticOrbitalStriated ductsDacryoadenitisSalivaTearTissuesSubmandibularDrynessPunctaInflammationAutoimmuneFossaCanaliculiAciniPathologyThyroidConjunctivaTumorDrainsTrigeminal nerveNerveInfiltratesInnervationOcular surfaceFluidDysfunctionCellsExpressionXerostomiaLymphaticStimulationSystemSurfaceStudyDiseaseSimilarTreatmentEffects
Secretion of lacrimal2
- Ultimately this two-neuron pathway involving both a preganglionic and postganglionic parasympathetic neuron increases the secretion of lacrimal fluid from the lacrimal gland. (wikipedia.org)
- The lacrimal nerve completes this long pathway by travelling through the lacrimal gland and sending branches to which it provides parasympathetic innervation to increase the secretion of lacrimal fluid. (wikipedia.org)
Artery1
- The lacrimal gland receives blood from the lacrimal artery, which is a branch of the ophthalmic artery. (wikipedia.org)
Salivary gland function2
- However, no significant improvement in the objective measures of lacrimal and salivary gland function was noted, despite effective depletion of blood B cells. (medscape.com)
- Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
Parasympathetic and sympathetic2
- The lacrimal nerve passes anteriorly in the orbit and through the lacrimal gland providing parasympathetic and sympathetic innervation to it. (wikipedia.org)
- Autonomic innervation of the salivary glands involves both parasympathetic and sympathetic input. (medscape.com)
Orbital4
- Anatomists divide the gland into two sections, a palpebral lobe, or portion, and an orbital lobe or portion. (wikipedia.org)
- The orbital lobe of the gland, contains fine interlobular ducts that connect the orbital lobe and the palpebral lobe. (wikipedia.org)
- Ectopic lacrimal gland tissue is reported to be located at epibulbar conjunctiva, other locations including orbital, eyelid, intraocular, lacrimal sac, and nasal mucosa sites [ 1 ]. (ekjo.org)
- Medially, the orbital wall consists of the frontal process of the maxilla, the lacrimal bone, the sphenoid, and the thin lamina papyracea of the ethmoid. (medscape.com)
Striated ducts1
- The gland lacks striated ducts. (wikipedia.org)
Dacryoadenitis1
- Inflammation of the lacrimal glands is called dacryoadenitis. (wikipedia.org)
Saliva10
- At rest, the parotid glands, located anterior to the ears, produce approximately 25% of oral saliva. (medscape.com)
- The sublingual glands, under the tongue, produce about 5% of the total oral saliva. (medscape.com)
- Approximately 1000 minor glands, localized to the cheeks, lips, and other intraoral mucosa, contribute about 7% to the whole saliva volume. (medscape.com)
- Saliva is primarily water but does vary in viscosity depending on the gland that produces it. (medscape.com)
- The parotids produce the most fluid saliva, as they are composed of serous acini, with the sublingual gland producing mucus from mucous acini. (medscape.com)
- The submandibular glands produce both serous and mucous saliva. (medscape.com)
- [ 4 ] Approximately 1-1.5 liters of saliva are produced by the glands in a day. (medscape.com)
- A number of different cellular signaling and regulatory systems in the acini and ducts are involved with saliva formation when the glands are stimulated by gustatory, masticatory, and psychic stimulation. (medscape.com)
- [ 7 ] age-related decline in saliva output was found to occur in the stimulated parotid, unstimulated submandibular/sublingual, and stimulated submandibular/sublingual glands. (medscape.com)
- Additional research suggests that changes may occur in the viscoelasticity of saliva with aging, particularly in saliva produced by the submandibular and sublingual glands. (medscape.com)
Tear3
- The lacrimal glands are paired exocrine glands, one for each eye, found in most terrestrial vertebrates and some marine mammals, that secrete the aqueous layer of the tear film. (wikipedia.org)
- The outer layer is composed of lipid from the meibomian glands, the middle aqueous layer is from the lacrimal gland and the third eyelid gland, and the inner layer of mucus that attaches the tear film to the cornea is from the conjunctival goblet cells. (merckvetmanual.com)
- The Schirmer tear test measures the aqueous portion of the tear film produced by the lacrimal and third eyelid glands. (merckvetmanual.com)
Tissues2
- Lacrimal gland tissues were harvested from E13.5 and E17.5 murine embryos and from mice 8 weeks of age ( adults ). (bvsalud.org)
- Iodine 131 is taken up by the thyroid through the sodium/iodide symporter (NIS), a protein that is also expressed in other tissues such as the salivary glands, stomach and breast. (bvsalud.org)
Submandibular4
- Inhibition of submandibular and lacrimal gland infiltration in nonobese diabetic mice by transgenic expression of soluble TNF-receptor p55. (jci.org)
- Besides a prominent mononuclear cell infiltration of the islets of Langerhans, nonobese diabetic (NOD) mice also show massive cellular infiltrates of the submandibular and lacrimal glands concomitant with histological signs of tissue damage. (jci.org)
- Direct evidence for an instrumental role of TNF-alpha in initiation and progression of submandibular and lacrimal gland infiltration is provided by the observed significant reduction in the extent of infiltration in nonobese diabetic mice transgenic for a soluble TNF receptor p55 fused to the Fc part of human IgG3. (jci.org)
- This protection from infiltration is paralleled by decreased expression of the adhesion molecules ICAM-1 and VCAM-1 in submandibular and lacrimal glands. (jci.org)
Dryness3
- Dryness of the mouth and eyes results from involvement of the salivary and lacrimal glands. (nih.gov)
- A new international consensus for diagnosis requires objective signs and symptoms of dryness including a characteristic appearance of a biopsy sample from a minor salivary gland or autoantibody such as anti-SS-A. Exclusions to the diagnosis include infections with HIV, human T-lymphotropic virus type I, or hepatitis C virus. (nih.gov)
- The objective of the present study was to evaluate the effects of iodine 131 on the salivary glands by subjective symptom of dryness in the mouth (xerostomia) and reduced salivary flow (hyposalivation) of patients with differentiated thyroid carcinoma submitted to radioiodine therapy. (bvsalud.org)
Puncta1
- Tears secreted collect in the fornix conjunctiva of the upper lid, and pass over the eye surface to the lacrimal puncta, small holes found at the inner corner of the eyelids. (wikipedia.org)
Inflammation3
- Lacrimal gland inflammation in rats and mice can result from various causes, including retrobulbar bleeding trauma, infectious agents such as sialodacryoadenitis virus in rats, and autoimmune disease. (nih.gov)
- Lacrimal gland inflammation should be diagnosed and assigned a severity grade whenever present. (nih.gov)
- The location of the inflammation within the gland (acini or duct) should be indicated in the pathology narrative. (nih.gov)
Autoimmune3
- These data suggest a central role of TNF-alpha in the initiation and progression of autoimmune tissue destruction of salivary glands and indicate beneficial effects of soluble TNF receptors in the treatment of organ-specific autoimmune diseases. (jci.org)
- Sjögren's syndrome is a chronic autoimmune disorder of the exocrine glands with associated lymphocytic infiltrates of the affected glands. (nih.gov)
- The accessibility of these glands to biopsy enables study of the molecular biology of a tissue-specific autoimmune process. (nih.gov)
Fossa2
- In humans, they are situated in the upper lateral region of each orbit, in the lacrimal fossa of the orbit formed by the frontal bone. (wikipedia.org)
- The margin is discontinuous at the lacrimal fossa. (medscape.com)
Canaliculi1
- These pass the tears through the lacrimal canaliculi on to the lacrimal sac, in turn to the nasolacrimal duct, which dumps them out into the nose. (wikipedia.org)
Acini1
- The lacrimal gland is a compound tubuloacinar gland, it is made up of many lobules separated by connective tissue, each lobule contains many acini. (wikipedia.org)
Pathology1
- Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
Thyroid1
- Characteristic features of GD with elevated IgG4 levels include lower echogenicity of the thyroid gland on ultrasound examination, peripheral blood eosinophilia, higher prevalence of orbitopathy, and better response to antithyroid drugs with a tendency to develop hypothyroidism when compared to patients with GD and normal levels of IgG4. (hindawi.com)
Conjunctiva2
- Expression of Aqp8 and Aqp9 mRNAs was detected in the adult lacrimal gland but not in the cornea , conjunctiva , or fetal lacrimal gland . (bvsalud.org)
- The levels of Aqp3 mRNAs and protein were much lower in the adult lacrimal gland but were readily detected in the adult cornea and conjunctiva . (bvsalud.org)
Tumor3
- Fine needle aspiration and incisional biopsy were done, which revealed ectopic lacrimal gland tumor in histology. (ekjo.org)
- Anterior segment photos of the patient with ectopic lacrimal gland tumor in the right eye. (ekjo.org)
- Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted therapies. (cdc.gov)
Drains1
- Blood from the gland drains to the superior ophthalmic vein. (wikipedia.org)
Trigeminal nerve1
- The lacrimal gland is innervated by the lacrimal nerve, which is the smallest branch of the ophthalmic nerve, itself a branch of the trigeminal nerve (CN V). After the lacrimal nerve branches from the ophthalmic nerve it receives a communicating branch from the zygomatic nerve. (wikipedia.org)
Nerve1
- As the zygomatic nerve travels anteriorly in the orbit it sends a communicating branch to the lacrimal nerve which carries the postganglionic parasympathetic axons. (wikipedia.org)
Infiltrates1
- Cells expressing TNF-alpha are mainly located in infiltrates, are absent in nonaffected glands, and are preferentially found among CD4 T cells. (jci.org)
Innervation2
- The parasympathetic innervation to the lacrimal gland is a complex pathway which traverses through numerous structures in the head. (wikipedia.org)
- Sympathetic innervation to the lacrimal gland is of less physiologic importance than the parasympathetic innervation, however there are noradrenergic axons found within the lacrimal gland. (wikipedia.org)
Ocular surface1
- The lacrimal gland produces tears which are secreted by the lacrimal ducts, and flow over the ocular surface, and then into canals that connect to the lacrimal sac. (wikipedia.org)
Fluid1
- The minor glands are primarily mucous producing, except those under the tongue, which produce serous fluid. (medscape.com)
Dysfunction1
- Longitudinal studies investigating the progression and intensity of salivary gland dysfunction in patients submitted to ablation with iodine 131 are scarce in the literature 2,4,8-9 . (bvsalud.org)
Cells5
- Each acinus consists of a grape-like mass of lacrimal gland cells with their apices pointed to a central lumen. (wikipedia.org)
- Secretion of TNF-alpha by gland-infiltrating cells was confirmed by an ELISPOT procedure. (jci.org)
- Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells. (bvsalud.org)
- Our study suggests that AQP8 and AQP9 may serve as markers for adult murine lacrimal gland , ductal, and myoepithelial cells . (bvsalud.org)
- HN - 2008 BX - Von Ebner's Glands MH - Cumulus Cells UI - D054885 MN - A05.360.319.114.630.535.200.500 MN - A06.407.312.497.535.300.500 MN - A11.436.300.500 MS - The granulosa cells of the cumulus oophorus which surround the OVUM in the GRAAFIAN FOLLICLE. (bvsalud.org)
Expression3
- Although AQPs play important roles in secretion in the lacrimal gland , the expression and localization of AQPs have not been clarified yet. (bvsalud.org)
- In the current study, we investigated the expression pattern of AQP family members in the murine lacrimal gland during development. (bvsalud.org)
- Expression of p16 in ACCs in the lacrimal gland. (molvis.org)
Xerostomia1
- [ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)
Lymphatic2
- No lymphatic vessels have been observed draining the lacrimal gland. (wikipedia.org)
- AN - do not confuse with SURGICAL STOMATA HN - 2008 BX - Diaphragmatic Stomata BX - Lymphatic Stomata BX - Stomata, Peritoneal FX - Surgical Stomas MH - Von Ebner Glands UI - D054838 MN - A03.556.500.760.906 MN - A10.336.779.906 MN - A14.549.760.906 MS - Small tubulo-alveolar salivary glands located beneath the circumvallate and foliate papillae. (bvsalud.org)
Stimulation1
- The patients did not receive any recommendation for home salivary gland stimulation, during the period of this study. (bvsalud.org)
System1
- The salivary system is composed of 3 major gland sets and multiple minor glands. (medscape.com)
Surface1
- [6] Another treatment that is sometimes suggested is lacrimal plugs that prevent tears from draining from the surface of the eye. (wikipedia.org)
Study1
- Genetic variants in DNA double-strand break repair genes and risk of salivary gland carcinoma: a case-control study. (cdc.gov)
Disease1
- I. Lacrimal disease in the rat. (nih.gov)
Similar1
- This thesaurus page includes all potential synonyms, words with the same meaning and similar terms for the word lacrimal gland . (synonyms.com)
Treatment1
- In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)
Effects1
- The beta radiation of iodine 131 exerts cytotoxic effects on the salivary glands because these organs are highly radiosensitive 5 . (bvsalud.org)