• Kynureninase
  • Alternatively, KYN is converted by kynurenine monooxygenase (KMO) into 3-hydroxykynurenine (3-HK), which can be transaminated into xanthurenic acid (XA) by KATs or, alternatively, metabolized into 3-hydroxyanthranylic acid (3-HANA) by kynureninase. (frontiersin.org)
  • acid
  • Here, we show that xanthurenic acid (XA), the transamination product of 3-hydroxykynurenine, is more efficacious than L -kynurenine in causing relaxation of a resistance artery, but fails to relax pre-contracted aortic rings. (frontiersin.org)