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  • novel
  • We then evaluated (1) whether epigenetic markers are associated with estimated glomerular filtration rate (eGFR), (2) whether the significantly associated markers are also associated with traditional risk factors and/or novel biomarkers for eGFR, and (3) how much additional variation in eGFR is explained by epigenetic markers beyond established risk factors and biomarkers. (hindawi.com)
  • tumor
  • This effect is augmented by the use of tumor necrosis factor It has been proposed that this treatment (accompanied by antiretroviral treatment) has the potential to purge the virus from infected individuals. (wikipedia.org)
  • epigenetic
  • Beside the core Oct4-Sox2-Nanog circuitry, accumulating regulators, including transcription factors, epigenetic modifiers, microRNA and signaling molecules have also been found to play important roles in preserving pluripotency. (mdpi.com)
  • However, six epigenetic markers were still able to significantly predict eGFR after adjustment for other risk factors. (hindawi.com)
  • Insulin
  • Defects in KLF11 affect glucose metabolism, insulin transcription, insulin processing, and insulin secretion which cause type 2 diabetes in adults and maturity-onset diabetes of the young type 7. (wikipedia.org)
  • known
  • It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element (NRSE, also known as RE1). (wikipedia.org)
  • AMOTL2 is also known to be an inhibitor of Wnt signaling, a pathway with known associations to cancer development, and to be a factor for angiogenesis, a process essential to tumour maintenance and metastasis. (wikipedia.org)