Klebsiella infections. Medical search. Frequent questions

Multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae , particularly carbapenem-resistant strains (CR- Kp ) causing high mortality and morbidity, are critical concerns[ 1 ]. (biorxiv.org)
Orally delivered recombinant bacteriocins, like klebicins, could be employed as oral antimicrobials to eradicate multidrug-resistant Klebsiella from the intestinal tract prior to/during hospitalization. (ecco-ibd.eu)
Multidrug resistant (MDR) Klebsiella pneumoniae is a major cause of healthcare-associated infections around the world, with attendant high rates of morbidity and mortality. (ibm.com)
Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups. (microbiologyresearch.org)
Themanagement of severe neurologic infections due to multidrug-resistant (MDR) Klebsiella pneumoniae infection remains a challenge. (figshare.com)
Infections caused by multidrug resistant (MDR) Klebsiella pneumoniae are difficult to treat with conventional antibiotics. (researchgate.net)
The absence of new, effective anti-gram-negative antibiotics makes infection control the most important countermeasure against multidrug-resistant gram-negative pathogens. (asm.org)
Complicated infections from multidrug-resistant Gram-negative bacteria (MDR-GNB) represent a serious problem presenting many challenges. (mdpi.com)

In Chile, although a sustained increase in CR- Kp infections has been observed, few strains have been described at the genomic level, lacking molecular details of their resistance and virulence determinants and the mobile elements mediating their dissemination. (biorxiv.org)
A search of the computerized database at the National Taiwan University Hospital was made for cefotaxime-resistant and cefmetazole-susceptible isolates of Escherichia coli and Klebsiella pneumoniae (which may be extended-spectrum β-lactamase-producing strains) in pediatric wards and intensive care units between 1999 and 2001. (ntu.edu.tw)
Results indicate that hospitalized patients become infected with their colonizing strains, supporting the strong association between colonization and bloodstream infections. (amr-insights.eu)
The article acknowledges the formation of bacterial biofilms in strains of bacteria species Klebsiella oxytoca and Klebsiella pneumoniae when grown in liquid media under the influence of negative factors (chemical factor) - containing agents. (iimmun.ru)
NDM-producing Klebsiella pneumoniae strains represent major clinical and infection control challenges, particularly in resource-limited settings with high rates of antimicrobial resistance. (ox.ac.uk)
Infection control may be effective in terminating outbreaks caused by particular strains, even in areas with widespread resistance, although this study could not demonstrate evidence supporting specific interventions. (ox.ac.uk)
This plasmid-borne resistance gene was found in strains of Klebsiella quasipneumoniae isolated from samples of human raw sewage collected over several months. (biomedcentral.com)
Here we describe the first detection in Italy of the mcr-10 gene, carried by strains of Klebsiella quasipneumoniae . (biomedcentral.com)
Twenty ESBL producing strains (15%) including Escherichia coli (n = 9), Klebsiella pneumoniae (n = 7), Klebsiella oxytoca (n = 2) and Enterobacter aerogenes (n = 2) were detected and further analyzed for their resistance transfer features, plasmid profile and nature of the resistance genes. (scielo.br)
Garlic and tea have antibacterial activity against Klebsiella , as well as drug resistant strains of Saphylococci, Enterococci and Psedomonas aeruginosa . (pakalertpress.com)

Infections caused by all three bacteria are treated with antibiotics given by vein (intravenously). (msdmanuals.com)
Klebsiella , Enterobacter , and Serratia bacteria reside in the intestine of many healthy people and rarely cause infection in them. (msdmanuals.com)
Infections with these bacteria are often acquired in hospitals and long-term care facilities. (msdmanuals.com)
Infection can spread up the urinary tract to the kidneys, or uncommonly the kidneys may become infected through bacteria in the. (msdmanuals.com)
Rarely, Klebsiella bacteria cause pneumonia in people who live outside a health care facility (in the community), usually in people with an alcohol use disorder, older people, people with diabetes, or people with a weakened immune system. (msdmanuals.com)
Then Klebsiella bacteria are able to multiply and produce the toxin. (msdmanuals.com)
Both inhalation and instillation exposure to Cu NPs significantly decreased the pulmonary clearance of K.p.-exposed mice measured 24 hr after bacterial infection following Cu NP exposure versus sham-exposed mice also challenged with K.p (1.4 × 10(5) bacteria/mouse). (cdc.gov)
Since 2011 a global explosion of klebsiella infections has been reported and most importantly this bacteria is resistant to a large number of broad spectrum antibiotics. (selfgrowth.com)
In modern, the sepsis is managed using broad spectrum antibiotics but in klebsiella sepsis the choice of antibiotic is to be done with precaution as the bacteria is resistant to multiple antibiotics.Along with antibiotics intravenous fluid is also administered to correct the perfusion abnormalities with corticosteroids injection to reduce inflammation. (selfgrowth.com)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefizox and other antibacterial drugs, Cefizox should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
Kadouri hopes that one day medical practitioners can use these predator bacteria to supplement antibiotic drugs in treating life-threatening infections. (newswise.com)
Klebsiella pneumoniae bacteria are major pathogens in human and animals. (pasteur.fr)
These bacteria can cause mild udder infections with a mild increase in somatic cell count and slight reduction in milk production. (cornell.edu)
Therefore, effective strategies must be implemented to combat antibiotic-resistant bacteria, along with stricter adherence to infection control programmes. (who.int)
You can get E. coli infections by eating foods containing the bacteria. (medlineplus.gov)

Common klebsiellae infections in humans include (1) community-acquired pneumonia, (2) UTI, (3) nosocomial infection, (4) rhinoscleroma and ozena, (5) chronic genital ulcerative disease, and (6) colonization. (medscape.com)
The in vivo efficacy studies showed that pBut_20 alleviated K. pneumonia lung infection without inducing damage to major organs. (ibm.com)
The polymer with optimal composition alleviates Klebsiella pneumonia lung infection without inducing damage to major organs. (ibm.com)
Other conditions such as pneumonia or urinary tract infections can trigger the release of counter-regulatory hormones that may contribute to the decrease in insulin's activity and secretion. (ascls.org)
Klebsiella pneumoniae is a common hospital-acquired pathogen, causing classical K. pneumoniae (CKp) infections such as pneumonia, urinary tract infection, intra-abdominal infection and bacteremia in immunocompromised patients [ 1 ]. (biomedcentral.com)
4 Cephalosporins as bactericidal, cell wall-active β-lactam agents were introduced in the 1980s and as a result of effectiveness against broad-spectrum β-lactamases became standard for treatment of severe conditions such as bloodstream infections, pneumonia and intra-abdominal infections, until ESBLs started compromising usefulness in response to overuse and selective pressure. (ajlmonline.org)
These infections can take the form of sepsis, urinary tract infection, pneumonia and wound infections. (selfgrowth.com)
In klebsiella sepsis, it's obvious that the reason for sepsis is the klebsiella infection in the body like klebsiella pneumonia, abdominal infections, klebsiella urinary tract infection and blood stream infection. (selfgrowth.com)
Klebsiella pneumonia showing consolidations and fibrosis in anteroposterior view of lungs in X-ray and sputum test in this case. (selfgrowth.com)
Within the frame of the DFG-funded Transregional Collaborative Research Center SFB-TR 84 "Innate Immunity of the Lung: Mechanisms of Pathogen Attack and Host Defence in Pneumonia" we help to elucidate mechanisms of early pathogen attack in lung infection. (fu-berlin.de)
The new guidelines are designed to reduce the incidence of pneumonia and other severe, acute lower respira- tory tract infections in acute-care hospitals and in other health-care settings (e.g., ambulatory and long-term care institu- tions) and other facilities where health care is provided. (cdc.gov)

Klebsiella pneumoniae, Klebsiella oxytoca, and Klebsiella granulomatis . (medscape.com)
Foram detectadas vinte cepas produtoras de ESBL, entre as quais Escherichia coli (n=9), Klebsiella pneumoniae (n=7), Klebsiella oxytoca (n=2) e Enterobacter aerogenes (n=2), que foram posteriormente analisadas quanto a suas características de transferência de resistência, perfil plasmidial e natureza dos genes de resistência. (scielo.br)
Many labs have adopted CLSI recommendations and only attempted to detect ESBLs in Escherichia coli , Klebsiella pneumoniae , K. oxytoca , and Proteus mirabilis ( 8 ). (asm.org)

Enterobacter aerogenes Hormaeche and Edwards 1960 (Approved Lists 1980) and Klebsiella mobilis Bascomb et al. (wikipedia.org)
Following entrance of Enterobacter or Citrobacter into the mammary gland, most infections are of short duration, although a handful may become chronic, lasting more than 100 days. (cornell.edu)

[ 2 ] In recent years, klebsiellae have become important pathogens in nosocomial infections. (medscape.com)
Infection control can prevent additional infections and the spread of resistant pathogens and thereby reduce the need to use antibiotics. (asm.org)

This retrospective case-control study aims to evaluate the clinical outcomes of patients diagnosed with nosocomial carbapenem-resistant Klebsiella infection (CRK), identify risk factors of this infection, and determine mortality rate. (journalmeddbu.com)
We sequenced carbapenem-resistant K. pneumoniae isolates from 26 individuals involved in several infection case clusters in a Nepali neonatal unit and 68 other clinical Gram-negative isolates from a similar time frame, using Illumina and PacBio technologies. (ox.ac.uk)

ABSTRACT The emergence and rapid spread of antibiotic-resistant Klebsiella pneumoniae isolates harbouring the blaKPC gene that encodes for carbapenemase production have complicated the management of patient infections. (who.int)

The most prevalent HAI are the Klebsiella species. (ecco-ibd.eu)
One species of Klebsiella produces a toxin that can cause inflammation of the colon and bleeding (hemorrhagic colitis) after antibiotics are taken. (msdmanuals.com)
Initial antimicrobial choice is empiric, and in simple infections should cover Staphylococcus and Streptococcus species. (aafp.org)

Organisms previously known as Klebsiella ozaenae and Klebsiella rhinoscleromatis are considered nonfermenting subspecies of K pneumoniae that have characteristic clinical manifestations. (medscape.com)
Differentiating nosocomial colonization from infection presents a formidable challenge in clinical practice. (medscape.com)
Clinical Microbiology and Infection. (wikipedia.org)
This case provides clinical evidence that the intrathecal, intravenous and aerosol inhalation of colistin sulfate by multichannel application can be a last resort in refractory intracranial infection by MDR K. pneumoniae. (figshare.com)
Hypervirulent Klebsiella pneumoniae (HVKp) infections have distinct clinical manifestations from classical K. pneumoniae infections. (biomedcentral.com)
Even though the diagnostic criteria of HVKp infections has still not been formally established [ 7 ], definition of HVKp infections should be based on clinical manifestations rather than microbiological analyses, since molecular analyses of virulence genes do not seems to be feasible in many microbiology laboratories. (biomedcentral.com)
For precise surveillance of the incidence and clinical spectrum of HVKp infections, proper diagnostic criteria should be established, and if microbiology methods were to be applied, they should be as simple as possible to be used as routine practice in microbiology laboratories. (biomedcentral.com)
A 62-year-old diabetic man with a history of right total knee arthroplasty 11 years prior who had suffered multiple episodes of prosthetic knee infection despite numerous surgeries and prolonged courses of antibiotics, with progressive clinical worsening and development of severe allergies to antibiotics, had been offered limb amputation for persistent right prosthetic knee infection due to Klebsiella pneumoniae complex. (elsevierpure.com)
Because of the clinical course, on day plus 1, physicians suspected a possible dengue virus infection. (cdc.gov)
Simple infections are usually monomicrobial and present with localized clinical findings. (aafp.org)
To compare the clinical impact of a prophylactic treatment with sublingual immunostimulation in the prevention of recurrent urinary tract infections (rUTIs) with the use of antibiotics. (frontiersin.org)

The risk of acquiring a urinary tract infection depends on the method and duration of catheterization, the quality of catheter care, and host susceptibility. (cdc.gov)

Reductions in CLABSIs caused by Staphylococcus aureus were more marked than reductions in infections caused by gram-negative rods, Candida spp. (cdc.gov)
Most community-acquired infections are caused by methicillin-resistant Staphylococcus aureus and beta-hemolytic streptococcus. (aafp.org)

Enfermedad granulomatosa producida por infección de KLEBSIELLA RHINOSCLEROMATIS. (bvsalud.org)
A granulomatous disease caused by KLEBSIELLA RHINOSCLEROMATIS infection. (bvsalud.org)

Mortality in KPC-producing Klebsiella pneumoniae bloodstream infections: a changing landscape. (bvsalud.org)
A retrospective cohort study of 222 patients with K. pneumoniae bloodstream infections (BSIs) was performed. (biomedcentral.com)
Risk factors for HVKp infections in patients with K. pneumoniae bloodstream infections (BSIs) has been studied. (biomedcentral.com)

Carbapenems are last-resort antibiotics for treating severe infections caused by MDR Enterobacteriaceae [ 3 ]. (biorxiv.org)
Progressive reduction in potency of antibiotics capable of treating MDR K. pneumoniae infections - including lung infection - as a consequence of escalating drug resistance provides the motivation to develop drug candidates targeting MDR K. pneumoniae. (ibm.com)
infections accordingly become quickly resistant to standard antibiotics during treatment, necessitating a change in antibiotic to avoid worsening of the sepsis. (wikipedia.org)
We hypothesized that activation of innate effector systems could sensitize MDR Klebsiella to conventional antibiotics. (researchgate.net)

A distinctive form of tissue-invasive community-associated Klebsiella pneumoniae infection, typified by primary liver abscess and bacteremia, has been well known in Asia for 2 decades ( 1 - 4 ). (cdc.gov)
Sepsis and Septic Shock Sepsis is a serious bodywide response to bacteremia or another infection plus malfunction or failure of an essential system in the body. (msdmanuals.com)

BACKGROUND: Klebsiella pneumoniae causes serious, life-threatening infections in humans in endemic and epidemic settings. (duke.edu)

Siu LK , Yeh K-M , Lin J-C , Fung C-P , Chang F-Y . Klebsiella pneumoniae liver abscess: a new invasive syndrome. (microbiologyresearch.org)
The hallmark of HVKp infections are liver abscess formation and metastatic infections. (biomedcentral.com)
reported that patients with HVKp infection had higher proportions of diabetes mellitus, and their infections had significantly higher propensity to liver abscess formation among Japanese patients with K. pneumoniae BSIs [ 12 ]. (biomedcentral.com)

The urinary tract is the most common site of nosocomial infection, accounting for more than 40% of the total number reported by acute-care hospitals and affecting an estimated 600,000 patients per year (1). (cdc.gov)
The control group was randomly selected among patients matched for gender who were hospitalized within the same period (±15 days) and had nosocomial infection but without CRK growth in cultures. (journalmeddbu.com)

Klebsiella pneumoniae (Kp) reference strain Kp52.145 is widely used in experimental Klebsiella pathophysiology. (microbiologyresearch.org)

This study aimed to investigate the antimicrobial efficacy of orally delivered Eudragit - coated klebicin (KvarIa) in a murine lower gastrointestinal tract model of K. quasipneumoniae infection. (ecco-ibd.eu)
Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model. (cdc.gov)
METHODS: We used Klebsiella pneumoniae (K.p.) in a murine lung infection model to determine if pulmonary bacterial clearance is enhanced or impaired by Cu NP exposure. (cdc.gov)

If we talk about klebsiella sepsis then it is most common in immunocompromised populations like patients suffering from cancer, diabetes, children and others. (selfgrowth.com)
In this article our main focus will remain on klebsiella induced sepsis. (selfgrowth.com)
Now let's discuss klebsiella induced sepsis in detail. (selfgrowth.com)
Sepsis is termed as the body's extreme reaction to any infection (in this case reaction to klebsiella infection) and extreme reaction requires emergency medical attention. (selfgrowth.com)
Sepsis is a hard to identify condition, but is typically denoted by high respiratory rate, high high rate, low or high body temperature, low or high white blood cell count and a suspected or known infection in the body. (selfgrowth.com)
Laboratory testing may be required to confirm an uncertain diagnosis, evaluate for deep infections or sepsis, determine the need for inpatient care, and evaluate and treat comorbidities. (aafp.org)

In addition to carrying genes for virulence factors RmpA, aerobactin and salmochelin, plasmid II has acquired in SB5881, the conjugation machinery gene cluster from plasmid I. We report the first case of community-acquired infection caused by a hypervirulent ST66-K2 Kp strain in Europe. (microbiologyresearch.org)
The system allows early identification of patients with K. pneumoniae BSIs in whom hypervirulent infections should be evaluated. (biomedcentral.com)

The objective of this study was to determine whether the incidence of K. pneumoniae bloodstream infection (BSI) was higher during warm months. (duke.edu)
An increased incidence of these infections in a herd warrants reassessment of the teat dip product used in the dairy and application methods. (cornell.edu)
To investigate the incidence, microbial aetiology, antimicrobial resistance profile, and mortality rate of healthcare- associated infections in intensive care units in the Islamic Republic of Iran. (who.int)

We found 4 additional patients infected with K . pneumoniae in 2009 who did not have invasive infections. (cdc.gov)
The presence of invasive devices in hospitalized patients greatly increases the likelihood of infection. (medscape.com)
Patients with these infections have similar presentations to those with infections caused by other organisms. (medscape.com)
Health-care--associated infections (HAIs) affect 5% of patients hospitalized in the United States each year. (cdc.gov)
Health-care--associated infections (HAIs) account for a substantial portion of health-care--acquired conditions ( 1 ) that harm patients receiving medical care. (cdc.gov)
Reported infection rates vary widely, ranging from 1%-5%, after a single brief catheterization (3) to virtually 100% for patients with indwelling urethral catheters draining into an open system for longer than 4 days (4). (cdc.gov)
In these studies, errors in maintaining sterile closed drainage were common and predisposed patients to infection. (cdc.gov)
Such infection in otherwise healthy patients is often asymptomatic and is likely to resolve spontaneously with the removal of the catheter. (cdc.gov)
RÉSUMÉ L'émergence et la propagation rapide des souches de Klebsiella pneumoniae résistantes aux antibiotiques et porteuses du gène blaKPC codant la production de carbapénèmases ont compliqué la prise en charge des infections des patients. (who.int)
Due to the severe sequelae of these complications, method to identify patients at-risk of HVKp infections should be developed. (biomedcentral.com)
In addition, based on such criteria, methods to identify patients with K. pneumoniae BSIs who are at-risk of HVKp infections should be investigated. (biomedcentral.com)
Patients with complicated infections, including suspected necrotizing fasciitis and gangrene, require empiric polymicrobial antibiotic coverage, inpatient treatment, and surgical consultation for debridement. (aafp.org)
Cryptococcosis is a well-recognised infection in immunocompromised patients, although its prevalence varies with the type of immune defect. (annals.edu.sg)
Healthcare-associated infections are a major cause of mortality worldwide, especially in intensive care units where severely ill patients have limited physical space. (who.int)
This observational study retrospectively reviewed the medical records of 1722 intensive care units patients with confirmed healthcare-associated infections at hospitals affiliated with Mashhad University of Medical Sciences in 2017-2019. (who.int)
Healthcare-associated infections in nearly half of intensive care unit patients were fatal, especially when caused by Acinetobacter spp. (who.int)

Biofilms, as a community of microorganisms cause many chronic infections (meningitis, inflammatory diseases of the oral cavity, urogenital infections) and create problems in the industry (fouling of processing equipment, ship hulls, oil platforms, biocorrosion metal products). (iimmun.ru)

In this study, we report a degradable guanidinium-functionalized polycarbonate with unexpected antimicrobial activity and selectivity towards MDR Klebsiella pneumoniae. (ibm.com)
Our research aimed to use synthetized aroylated phenylenediamines (APDs) to induce the expression of cathelicidin antimicrobial peptide gene (CAMP) to minimize the necessity of antibiotic use during infection. (researchgate.net)

CDC defines a CLABSI as recovery of a pathogen from a blood culture (a single blood culture for organisms not commonly present on the skin and two or more blood cultures for organisms commonly present on the skin) in a patient who had a central line at the time of infection or within the 48-hour period before development of infection. (cdc.gov)

Availability of iron increases host susceptibility to K pneumoniae infection. (medscape.com)

Central line--associated blood-stream infections (CLABSIs) are one of the most deadly types of HAIs, with a mortality rate of 12%--25% ( 2 ). (cdc.gov)
CI, and to identify univariate and multivariate predictors of healthcare-associated infection mortality. (who.int)

Phage therapy is a promising strategy to manage such infections including those involving antibiotic-resistant microbes, and to target microbial biofilms. (elsevierpure.com)

Abscess in the Lungs A lung abscess is a pus-filled cavity in the lung surrounded by inflamed tissue and caused by an infection. (msdmanuals.com)
In this study, the structures of the polymers were optimized for the treatment of MDR Klebsiella pneumoniae lung infection. (ibm.com)
Taken together, pBut_20 is promising for treating MDR Klebsiella pneumoniae lung infection in vivo. (ibm.com)
CONCLUSIONS: Cu NP exposure impaired host defense against bacterial lung infections and induced a dose-dependent decrease in bacterial clearance in which even our lowest dose demonstrated significantly lower clearance than observed in sham-exposed mice. (cdc.gov)

Thus, exposure to Cu NPs may increase the risk of pulmonary infection. (cdc.gov)
To test the accuracy of the Ultra assay in children, researchers with the Beijing Pediatric Research Institute and Beijing Children's Hospital enrolled 93 children with pulmonary tuberculosis and 128 children with respiratory tract infections. (umn.edu)

Limited antibiotic treatment regimens make treatment of severe MDR K. pneumoniae infection more difficult. (figshare.com)

See related handout on skin and soft tissue infections , written by the authors of this article. (aafp.org)
Skin and soft tissue infections result from microbial invasion of the skin and its supporting structures. (aafp.org)
Skin and soft tissue infections (SSTIs) account for more than 14 million physician office visits each year in the United States, as well as emergency department visits and hospitalizations. (aafp.org)
Comorbidities, skin and soft tissue infections, and infections with Acinetobacter spp. (who.int)

Scholars@Duke publication: Seasonal variation in Klebsiella pneumoniae bloodstream infection on 4 continents. (duke.edu)

K granulomatis infection can result in granuloma inguinale or donovanosis, although these are uncommon in developed temperate countries. (medscape.com)

The genus Klebsiella belongs to the tribe Klebsiellae, a member of the family Enterobacteriaceae.The organisms are named after Edwin Klebs, a 19th century German microbiologist. (medscape.com)

Genome sequencing of an extended series of NDM-producing Klebsiella pneumoniae isolates from neonatal infections in a Nepali hospital characterizes the extent of community- versus hospital-associated transmission in an endemic setting. (ox.ac.uk)

Although not all catheter-associated urinary tract infections can be prevented, it is believed that a large number could be avoided by the proper management of the indwelling catheter. (cdc.gov)
Adoption of the closed method of urinary drainage has markedly reduced the risk of acquiring a catheter-associated infection, but the risk is still substantial. (cdc.gov)
Host factors which appear to increase the risk of acquiring catheter-associated urinary tract infections include advanced age, debilitation, and the postpartum state (7,8). (cdc.gov)
Catheter-associated urinary tract infections are generally assumed to be benign. (cdc.gov)
The natural history of catheter associated urinary tract infections has been largely unstudied. (cdc.gov)

This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)

The intensive care units (ICUs), in particular, are hotbeds for contracting infections ( 5 ). (who.int)

Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. (ajlmonline.org)

Organisms that produce ESBLs are an important reason for therapy failure with cephalosporins and have serious consequences for infection control. (ajlmonline.org)

KEGG GENOME: Klebsiella pneumoniae subsp. (genome.jp)
Complete Genome Sequence of Klebsiella pneumoniae Strain ATCC 43816 KPPR1, a Rifampin-Resistant Mutant Commonly Used in Animal, Genetic, and Molecular Biology Studies. (genome.jp)

Organisms3

Diseases1

Chemicals and Drugs1

Multidrug-resistant8

Strains10

Bacteria15

Pneumonia11

Oxytoca3

Enterobacter2

Pathogens2

Carbapenem-resistant2

Abstract1

Species3

Clinical11

Urinary tract inf1

Staphylococcus2

Rhinoscleromatis2

Pneumoniae bloodstream infections3

Antibiotics4

Bacteremia2

Humans1

Liver abscess3

Nosocomial infection2

Pathophysiology1

Murine3

Sepsis6

Hypervirulent2

Incidence3

Patients16

Microorganisms1

Antimicrobial2

Pathogen1

Susceptibility1

Mortality2

Antibiotic-resistant1

Lung4

Pulmonary2

Severe1

Skin and soft tissue infections4

Bloodstream infection1

Granulomatis1

Enterobacteriaceae1

Isolates1

Catheter-associated5

Microbial1

Intensive Care Units1

Extended-spectrum1

ESBLs1

Genome2