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  • PORT (Psychosocial Oncology Research Training) builds on the extant knowledge from various relevant disciplines such as psychology, nursing, medicine, health care management, human kinetics, epidemiology, and philosophy at four participating Canadian universities to share in their findings pertaining to the development, implementation and dissemination of innovative psychosocial interventions that optimally assist individuals in their adjustment to cancer. (bvsalud.org)
  • In biochemistry, Michaelis-Menten kinetics, named after Leonor Michaelis and Maud Menten, is the simplest case of enzyme kinetics, applied to enzyme-catalysed reactions of one substrate and one product. (wikipedia.org)
  • Enzyme kinetics is the study of the rates of enzyme-catalysed chemical reactions . (wikipedia.org)
  • We have recently noted that fine-tuning translation kinetics selection, or the right combination of preferred and rare codons in the capsid coding region, is necessary to get regulated ribosome traffic to guarantee the proper capsid folding ( 10 ). (cdc.gov)
  • These structural data might define ObgE as a specialized translation factor related to stress responses, and provide a framework towards future elucidation of functional interplay between ObgE and ribosome-associated (p)ppGpp regulators. (rcsb.org)
  • p)ppGpp not only controls various stages of central dogma processes (replication, transcription, ribosome maturation and translation) and central metabolism but also regulates various physiological processes such as pathogenesis, persistence, motility and competence. (bvsalud.org)
  • However, the slow hardening kinetics hampers the translation to the clinics. (upc.edu)
  • Knowledge of the subcutaneous tissue is important to understand the absorption kinetics after subcutaneous administration. (aspetjournals.org)
  • When the value of the Michaelis constant K m {\displaystyle K_{\mathrm {m} }} is numerically equal to the substrate concentration, the reaction rate is half of V {\displaystyle V} . Biochemical reactions involving a single substrate are often assumed to follow Michaelis-Menten kinetics, without regard to the model's underlying assumptions. (wikipedia.org)
  • In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. (wikipedia.org)
  • Ribozymes also perform a more limited set of reactions, although their reaction mechanisms and kinetics can be analysed and classified by the same methods. (wikipedia.org)
  • Due to the discrete manner of molecular assembly in cell signalling and gene regulation, we define a framework of membrane systems equipped with discretised forms of reaction kinetics in concert with variable intramolecular structures. (springer.com)
  • Do literature search then perform electrophoresis and kinetics experiments independently or as a team in a safe manner and report and results using scientific writing. (uaeu.ac.ae)
  • Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism , how its activity is controlled, and how a drug or a modifier ( inhibitor or activator ) might affect the rate. (wikipedia.org)
  • Describe the kinetics, mechanism and role of enzymes in living systems. (uaeu.ac.ae)
  • Thus, our findings might have uncovered an under-recognized mechanism of translation control by environmental cues. (rcsb.org)
  • When enzymes bind multiple substrates, such as dihydrofolate reductase (shown right), enzyme kinetics can also show the sequence in which these substrates bind and the sequence in which products are released. (wikipedia.org)
  • Also, the presystemic catabolism leading to incomplete bioavailability is little understood, both the involved enzymes and its translation across species. (aspetjournals.org)
  • However, an accumulation of low molecular weight subcomplexes suggested a complex I assembly/stability defect, which was further demonstrated by reversibly inhibiting mitochondrial protein translation with doxycycline. (nih.gov)
  • Although these mechanisms are often a complex series of steps, there is typically one rate-determining step that determines the overall kinetics. (wikipedia.org)
  • Here, using pre-steady state fast kinetics we demonstrate that ObgE is an anti-association factor, which prevents ribosomal subunit association and downstream steps in translation by binding to the 50S subunit. (rcsb.org)
  • Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. (ucsf.edu)
  • On the basis of bio-chemical kinetics, we present a model of muscle fiber exhaustion based on hydrolytic ATP-ADP-P i dynamics, which are assumed to be length- and calcium activity-dependent. (frontiersin.org)
  • Most recently, several studies have developed inference methods based on nonlinear ordinary differential equations (ODEs) for the chemical kinetics and a Bayesian formalism on the network structure [ 24 - 27 ]. (biomedcentral.com)
  • His research focus has been in the areas of chemical thermodynamics, kinetics and transport. (serdp-estcp.org)
  • During carbon downshift, a lack of stringent response in relA deficient strain leads to disruption of the transcription-translation coordination, thus compromising the transcription processivity and further the timely expression of related catabolic operons for utilizing secondary carbon sources. (bvsalud.org)
  • Tight coordination between transcription and translation has long been recognized as the hallmark of gene expression in bacteria. (bvsalud.org)
  • In Escherichia coli cells, disruption of the transcription-translation coordination leads to the loss of transcription processivity via triggering Rho-mediated premature transcription termination. (bvsalud.org)
  • Knowledge translation in sport management remains largely implicit and is yet to be fully understood. (humankinetics.com)
  • This study examines how knowledge translation in sport management can be conceptualized and fostered. (humankinetics.com)
  • The authors draw on a comparative analysis of coproduced research projects in Belgium and Australia to identify the strategic, cognitive, and logistic translation practices that researchers adopt, as well as enablers and constraints that affect knowledge translation. (humankinetics.com)
  • The findings show ways in which knowledge translation may be facilitated and supported, such as codesign, boundary spanning, adaptation of research products, and linkage and exchange activities. (humankinetics.com)
  • We discuss implications of our model approach for enhancing muscle models in general, as well as a few aspects regarding the significance of phosphate kinetics as one contributor to muscle fatigue. (frontiersin.org)
  • In the absence of voltage, aminoglycosides are taken into cells and exert bacteriostatic effects by inhibiting translation. (elifesciences.org)
  • Application of QbD strategy in ascertaining the scalability of DLH EOP formulation would help pharmaceutical industries in the translation of EOP based drug delivery systems from R&D to market. (bvsalud.org)
  • a) zero-order kinetics, (b) drug candidate. (bvsalud.org)
  • These formulated EOP systems followed zero-order kinetics, a characteristic feature of EOPs. (bvsalud.org)
  • sefer yeṣira edition translation and text opened given by the JWST Mission price at Space Telescope Science Institute to be posts for Eastern companies group. (uboot-dillenburg.de)
  • Members Login Join directly Toggle navigationHomeScenes ScenesUpcomingCategoriesPicturesMX SeriesPornstarsShopLive ShowHot NewsAffiliate AffiliateBecome an AffiliatePreviousNextDISCLAIMERAANDACHT: military sefer yeṣira edition translation and text critical commentary texts and studies in ancient judaism supervisor bottle sole 18+)U books 18 example en will Disclaimer zijn, en existent levels commemorative, 43- lively experience beelden en teksten bevatten van research Flytrap of success shops. (uboot-dillenburg.de)
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  • Aminoglycosides are a potent class of translation inhibitor antibiotics with a broad activity spectrum. (elifesciences.org)
  • We have used rapid-kinetics measurements in vitro and molecular dynamics (MD) simulations in silico to investigate the relationship between GTP-binding properties and P-loop structural dynamics in the universally conserved Elongation Factor (EF) Tu. (uleth.ca)
  • In this first of two companion papers, model reference frames and joint centers are analyzed for repeatability, joint translations are measured, segment rigidity characterized, and sample joint angles presented. (cdc.gov)
  • He presently serves as a Project Leader, Research Translation Core (RTC) Leader, and Associate Director of Brown's NIEHS-supported Superfund Research Program (SRP). (serdp-estcp.org)
  • 1888PressRelease - Marpo Kinetics, the pioneer and industry leader in rope training, is celebrating the debut of it's newly redesigned Marpo Rope Trainers. (slideonline.com)
  • For rights of reproduction or translation of WHO publications, in part or in toto, application should be made to the Office of Publications, World Health Organization, Geneva, Switzerland. (inchem.org)
  • Translation: Activating aspects of a given muscle can influence the extent of its development. (humankinetics.com)
  • Translation: An intense workout, with minimal joint strain. (slideonline.com)
  • Click a Field or Translation tag to filter the publications. (ucsf.edu)
  • Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags. (ucsf.edu)
  • And more importantly, ObgE, as a (p)ppGpp effector, might also have a regulatory role in the production of the 50S subunit and its participation in translation under certain stressed conditions. (rcsb.org)
  • Molecular structures and how they relate to function, enzyme kinetics and bioenergetics are also fundamental. (unm.edu)