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  • tyrosine
  • Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival and resistance to cytotoxic therapy in multiple myeloma (MM). Recently, members of the cyclolignan family have been shown to selectively inhibit the receptor tyrosine kinase (RTK) activity of the IGF-1R beta-chain. (ad-astra.ro)
  • Amplification of the HER family of tyrosine kinases occurs in a subset of tumors. (mskcc.org)
  • PKMYT1 (Protein Kinase, Membrane Associated Tyrosine/Threonine 1) is a Protein Coding gene. (genecards.org)
  • GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity . (genecards.org)
  • assays
  • As demonstrated by in vitro kinase assays, PPP down-regulated the IGF-1 RTK activity without inhibiting the insulin RTK activity. (ad-astra.ro)
  • Assays are carried out in kinase assay buffer (50 mM of HEPES, pH 7.5, 10 mM of MgCl 2 , 5 mM of EGTA, 0.05% Brij-35) supplemented with 2 mM of DTT. (selleckchem.com)
  • apoptosis
  • Here we demonstrate that the Florin leaf methanol extracts inhibit growth of these bladder carcinoma cells by arresting cell cycle at the G2/M phase and inducing apoptosis. (hindawi.com)
  • regulator
  • Here, Arabidopsis thaliana CYCLIN-DEPENDENT KINASE G2 (CDKG2) was shown to act as a negative regulator of the salinity stress response, as well as being involved in the control of flowering time. (deepdyve.com)
  • Histidine kinase EnvZ, a transmembrane osmotic sensor for Escherichia coli, is a bifunctional enzyme having OmpR (its cognate response regulator) kinase and phosphorylated OmpR (OmpR-P) phosphatase activities. (semanticscholar.org)
  • enzymes
  • 3 Side: 1/6 * Avsnitt 1: Identifikasjon av kjemikaliet og ansvarlig firma 1.1 Produktidentifikator Handelsnavn: Enzymes in Kinase strips (2.5 or 5µl) Artikkelnummer: Turnkey Relevante, identifiserte anvendelser av stoffet eller stoffblandingen, samt anvendelser som frarådes Ikke noe mer relevant informasjon tilgjengelig. (docplayer.me)
  • 4 Side: 2/6 Handelsnavn: Enzymes in Kinase strips (2.5 or 5µl) (fortsatt fra side 1) Ytterligere informasjoner: Teksten til de fareangivelsene som er inkludert her, kan konsulteres i kapittel 16. (docplayer.me)
  • 5 Side: 3/6 Handelsnavn: Enzymes in Kinase strips (2.5 or 5µl) 7.3 Spesiell sluttbruk Ikke noe mer relevant informasjon tilgjengelig. (docplayer.me)
  • Recombinant Aurora A and B kinase enzymes and appropriate PanVera Z'-Lyte kinase assay kits are purchased. (selleckchem.com)
  • crucial
  • The MAP kinase signaling cascade Ras/Raf/MEK/ERK has been involved in a large variety of cellular and physiological processes that are crucial for life. (frontiersin.org)
  • cancers
  • Usually, bladder cancers are grouped into two types of clinical manifestation, depending on the pathological stage: low-grade (G1, G2)/noninvasive cancers (pTa, pT1) and high-grade (G3)/muscle invasive lesions (greater than pT2) [ 3 ]. (hindawi.com)
  • Expression
  • Vard and cGMP treatment also increased dual specificity protein phosphatase 10 (DUSP10) expression and reduced phospho-c-Jun N-terminal kinase (JNK) levels in the colon mucosa of Prkg2(+/+) but not Prkg2(-/-) mice. (tum.de)
  • phase
  • The cell cycle of these extract-treated cells (TCCSUP cells) was arrested at the G2/M phase as determined by flow cytometry. (hindawi.com)