Kinase drug targets. Medical search. Frequent questions

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Anatomy10

Cell Line, Tumor Cell Line Cells, Cultured Tumor Cells, Cultured HeLa Cells 3T3 Cells Cell Membrane Fibroblasts HEK293 Cells Cell Nucleus

Organisms9

Trypanosoma brucei brucei Mice, Knockout Rats, Sprague-Dawley Mice, Inbred C57BL Saccharomyces cerevisiae Mycobacterium tuberculosis Cattle Cricetinae Plasmodium falciparum

Diseases2

Neoplasms Trypanosomiasis, African

Chemicals and Drugs158

Phosphatidylinositol 3-Kinases Protein-Serine-Threonine Kinases Protein Kinases Protein Kinase Inhibitors Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Protein Kinase C p38 Mitogen-Activated Protein Kinases Cyclic AMP-Dependent Protein Kinases Mitogen-Activated Protein Kinase 1 p21-Activated Kinases Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Protein-Tyrosine Kinases Creatine Kinase CDC2 Protein Kinase Cyclin-Dependent Kinases MAP Kinase Kinase Kinases eIF-2 Kinase Casein Kinase II Casein Kinases Pyruvate Kinase Ribosomal Protein S6 Kinases MAP Kinase Kinase 1 Phosphotransferases (Alcohol Group Acceptor)Extracellular Signal-Regulated MAP Kinases Receptor Protein-Tyrosine Kinases Thymidine Kinase Aurora Kinases MAP Kinase Kinase 4 Mitogen-Activated Protein Kinases Glycogen Synthase Kinase 3 1-Phosphatidylinositol 4-Kinase Isoenzymes CDC2-CDC28 Kinases I-kappa B Kinase rho-Associated Kinases Enzyme Inhibitors Proto-Oncogene Proteins Protein Kinase C-delta Protein Kinase C-alpha Proto-Oncogene Proteins c-akt Diacylglycerol Kinase AMP-Activated Protein Kinases Recombinant Proteins Focal Adhesion Kinase 1 Intracellular Signaling Peptides and Proteins Myosin-Light-Chain Kinase Phosphoproteins Janus Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Ribosomal Protein S6 Kinases, 90-kDa Tyrosine TOR Serine-Threonine Kinases Protein Kinase C-epsilon MAP Kinase Kinase Kinase 1 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Protein Kinase C beta Cell Cycle Proteins Tetradecanoylphorbol Acetate MAP Kinase Kinase 2 Proteins RNA, Messenger Cyclin-Dependent Kinase 2 Serine Cyclic GMP-Dependent Protein Kinases Androstadienes Recombinant Fusion Proteins Cyclin-Dependent Kinase 5 Phosphoglycerate Kinase Chromones RNA, Small Interfering Antineoplastic Agents Phosphorylase Kinase Cyclic AMP Arginine Kinase Calcium Aurora Kinase B Nucleoside-Phosphate Kinase MAP Kinase Kinase 6 Pyrimidines Morpholines Casein Kinase I MAP Kinase Kinase 3 Mitogen-Activated Protein Kinase 8 Pharmaceutical Preparations Aurora Kinase A 3-Phosphoinositide-Dependent Protein Kinases Pyridines Focal Adhesion Kinase 2 Ligands Flavonoids Phosphatidylinositol 3-Kinase Adenosine Triphosphate Indoles Adenosine Kinase Protozoan Proteins DNA-Binding Proteins Lim Kinases Small Molecule Libraries Carrier Proteins Nucleoside-Diphosphate Kinase Membrane Proteins Choline Kinase Ribosomal Protein S6 Kinases, 70-kDa Transcription Factors Elongation Factor 2 Kinase Threonine raf Kinases MAP Kinase Kinase 7 Phosphotyrosine Phosphoprotein Phosphatases Receptor, Epidermal Growth Factor Adaptor Proteins, Signal Transducing DNA Primers Cyclin-Dependent Kinase 4 Janus Kinase 1 NF-kappa B Peptides Imidazoles Receptors, G-Protein-Coupled Bacterial Proteins Cyclin-Dependent Kinase Inhibitor p27 Nuclear Proteins Staurosporine Phosphoserine Multienzyme Complexes Piperazines MAP Kinase Kinase Kinase 5 Antiprotozoal Agents Glycogen Synthase Kinases Benzamides Mitogen-Activated Protein Kinase 9 Deoxycytidine Kinase Janus Kinase 3 TYK2 Kinase A Kinase Anchor Proteins DNA, Complementary Maleimides 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Checkpoint Kinase 2 Diglycerides Butadienes DNA-Activated Protein Kinase Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Death-Associated Protein Kinases Saccharomyces cerevisiae Proteins Insulin Isoquinolines Cyclin-Dependent Kinase Inhibitor p21 Phorbol 12,13-Dibutyrate Mitogen-Activated Protein Kinase 7 Epidermal Growth Factor Proto-Oncogene Proteins pp60(c-src)Acetate Kinase Enzyme Activators Proto-Oncogene Proteins c-abl

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Drug Discovery Drug Design Drug Delivery Systems Molecular Targeted Therapy Models, Molecular Transfection Blotting, Western Drug Repositioning Models, Biological Drug Evaluation, Preclinical Crystallography, X-Ray Cloning, Molecular Immunoblotting Sequence Alignment Precipitin Tests Mutagenesis, Site-Directed High-Throughput Screening Assays Gene Expression Profiling Inhibitory Concentration 50 Reverse Transcriptase Polymerase Chain Reaction Protein Interaction Mapping Electrophoresis, Polyacrylamide Gel Gene Knockdown Techniques Peptide Mapping Microscopy, Fluorescence

Phenomena and Processes46

MAP Kinase Signaling System Signal Transduction Phosphorylation Protein Binding Mutation Amino Acid Sequence Kinetics Protein Structure, Tertiary Substrate Specificity Binding Sites Transfection Enzyme Activation Sequence Homology, Amino Acid Apoptosis Base Sequence Catalytic Domain Gene Expression Regulation Gene Expression Regulation, Enzymologic Dose-Response Relationship, Drug Cell Proliferation Cell Cycle RNA Interference Cell Division Structure-Activity Relationship Genes, Essential Time Factors Cell Survival Molecular Structure Transcription, Genetic Metabolic Networks and Pathways Gene Expression Protein Transport Protein Conformation Down-Regulation Inhibitory Concentration 50 Phenotype Protein Processing, Post-Translational Up-Regulation Amino Acid Motifs Cell Movement Catalysis Gene Deletion Cell Differentiation Mitosis Gene Expression Regulation, Neoplastic src Homology Domains

Disciplines and Occupations4

Drug Discovery Drug Design Computational Biology Pharmacogenetics

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Phosphatidylinositol 3-Kinases MAP Kinase Signaling System Protein-Serine-Threonine Kinases Protein Kinases Protein Kinase Inhibitors Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Protein Kinase C p38 Mitogen-Activated Protein Kinases Cyclic AMP-Dependent Protein Kinases Drug Discovery Mitogen-Activated Protein Kinase 1 p21-Activated Kinases Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Protein-Tyrosine Kinases Creatine Kinase CDC2 Protein Kinase Cyclin-Dependent Kinases MAP Kinase Kinase Kinases Drug Design Signal Transduction Phosphorylation eIF-2 Kinase Casein Kinase II Casein Kinases Pyruvate Kinase Ribosomal Protein S6 Kinases Molecular Sequence Data Protein Binding MAP Kinase Kinase 1 Phosphotransferases (Alcohol Group Acceptor)Extracellular Signal-Regulated MAP Kinases Receptor Protein-Tyrosine Kinases Thymidine Kinase Aurora Kinases MAP Kinase Kinase 4 Mutation Amino Acid Sequence Mitogen-Activated Protein Kinases Glycogen Synthase Kinase 3 1-Phosphatidylinositol 4-Kinase Isoenzymes CDC2-CDC28 Kinases Kinetics I-kappa B Kinase rho-Associated Kinases Enzyme Inhibitors Drug Delivery Systems Protein Structure, Tertiary Substrate Specificity Proto-Oncogene Proteins Protein Kinase C-delta Binding Sites Protein Kinase C-alpha Molecular Targeted Therapy Cell Line, Tumor Models, Molecular Proto-Oncogene Proteins c-akt Diacylglycerol Kinase Transfection Blotting, Western AMP-Activated Protein Kinases Enzyme Activation Recombinant Proteins Cell Line Drug Repositioning Sequence Homology, Amino Acid Focal Adhesion Kinase 1 Models, Biological Intracellular Signaling Peptides and Proteins Apoptosis Drug Evaluation, Preclinical Myosin-Light-Chain Kinase Base Sequence Phosphoproteins Janus Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Ribosomal Protein S6 Kinases, 90-kDa Tyrosine TOR Serine-Threonine Kinases Protein Kinase C-epsilon MAP Kinase Kinase Kinase 1 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Protein Kinase C beta Cell Cycle Proteins Tetradecanoylphorbol Acetate Catalytic Domain MAP Kinase Kinase 2 Proteins RNA, Messenger Cyclin-Dependent Kinase 2 Serine Cyclic GMP-Dependent Protein Kinases Androstadienes Cells, Cultured Recombinant Fusion Proteins Crystallography, X-Ray Gene Expression Regulation

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