Kinase domain mutations. Medical search. Frequent questions

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Anatomy14

Cell Line, Tumor Cell Line Cell Membrane COS Cells Cells, Cultured HeLa Cells 3T3 Cells Tumor Cells, Cultured Cytoplasm Cell Nucleus CHO Cells HEK293 Cells Fibroblasts NIH 3T3 Cells

Organisms11

Escherichia coli Saccharomyces cerevisiae Cercopithecus aethiops Cricetinae Mice, Knockout Mice, Inbred C57BL Arabidopsis Drosophila Drosophila melanogaster Cattle Spodoptera

Diseases5

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lung Neoplasms Carcinoma, Non-Small-Cell Lung Adenocarcinoma Cell Transformation, Neoplastic

Chemicals and Drugs121

Benzamides Fusion Proteins, bcr-abl Piperazines Pyrimidines Protein Kinase Inhibitors Protein-Tyrosine Kinases Thiazoles Receptor, Epidermal Growth Factor Antineoplastic Agents Protein-Serine-Threonine Kinases Protein Kinases Quinazolines Phosphatidylinositol 3-Kinases Recombinant Fusion Proteins Recombinant Proteins Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Proto-Oncogene Proteins Receptor Protein-Tyrosine Kinases Protein Kinase C Mutant Proteins Cyclic AMP-Dependent Protein Kinases DNA-Binding Proteins p38 Mitogen-Activated Protein Kinases DNA Primers p21-Activated Kinases Mitogen-Activated Protein Kinase 1 Membrane Proteins Pyridazines Mitogen-Activated Protein Kinase Kinases Transcription Factors Tyrosine MAP Kinase Kinase Kinases JNK Mitogen-Activated Protein Kinases Carrier Proteins Mitogen-Activated Protein Kinase 3 Ligands Proto-Oncogene Proteins c-kit RNA, Messenger Cyclin-Dependent Kinases DNA DNA, Complementary eIF-2 Kinase Intracellular Signaling Peptides and Proteins Ribosomal Protein S6 Kinases Phosphotransferases (Alcohol Group Acceptor)Nuclear Proteins Phosphoproteins Isoenzymes Serine CDC2 Protein Kinase Creatine Kinase Adaptor Proteins, Signal Transducing Casein Kinase II Mitogen-Activated Protein Kinases Bacterial Proteins Casein Kinases MAP Kinase Kinase 1 Ribosomal Protein S6 Kinases, 90-kDa Pyruvate Kinase Cell Cycle Proteins HIV Reverse Transcriptase Extracellular Signal-Regulated MAP Kinases Janus Kinase 2 Proto-Oncogene Proteins c-abl MAP Kinase Kinase 4 1-Phosphatidylinositol 4-Kinase Thymidine Kinase Threonine Adenosine Triphosphate Aurora Kinases I-kappa B Kinase Drosophila Proteins rho-Associated Kinases Glycogen Synthase Kinase 3 Proto-Oncogene Proteins c-akt 3-Phosphoinositide-Dependent Protein Kinases Phosphotyrosine Fungal Proteins Trans-Activators Nucleoside-Phosphate Kinase CDC2-CDC28 Kinases Peptides Protein Kinase C-alpha Calcium Protein Kinase C-delta Proteins Enzyme Inhibitors Focal Adhesion Kinase 1 AMP-Activated Protein Kinases Codon, Nonsense Protein Isoforms Focal Adhesion Protein-Tyrosine Kinases Repressor Proteins Lim Kinases Diacylglycerol Kinase Nerve Tissue Proteins Glutathione Transferase Saccharomyces cerevisiae Proteins Peptide Fragments Codon MAP Kinase Kinase Kinase 1 Guanylate Kinase Receptor, Insulin Calcium-Calmodulin-Dependent Protein Kinase Type 2 Tetradecanoylphorbol Acetate Myosin-Light-Chain Kinase Protein Subunits Cytoskeletal Proteins TOR Serine-Threonine Kinases Arabidopsis Proteins Macromolecular Substances Green Fluorescent Proteins Phosphofructokinase-2 Actins Plant Proteins Phosphoserine fms-Like Tyrosine Kinase 3 Staurosporine Multienzyme Complexes Cysteine

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

DNA Mutational Analysis Amino Acid Substitution Mutagenesis, Site-Directed Models, Molecular Transfection Sequence Alignment Cloning, Molecular Polymerase Chain Reaction Pedigree Crystallography, X-Ray Blotting, Western Sequence Analysis, DNA Models, Biological Two-Hybrid System Techniques Precipitin Tests Immunoblotting Genetic Complementation Test Electrophoresis, Polyacrylamide Gel Chromosome Mapping Reverse Transcriptase Polymerase Chain Reaction Microscopy, Fluorescence Peptide Mapping Restriction Mapping Models, Genetic Mutagenesis, Insertional Genetic Testing Immunohistochemistry

Phenomena and Processes77

Mutation Drug Resistance, Neoplasm Genes, abl Protein Structure, Tertiary Point Mutation Mutation, Missense Phosphorylation Amino Acid Sequence Amino Acid Substitution Protein Binding Base Sequence Sequence Homology, Amino Acid Binding Sites MAP Kinase Signaling System Signal Transduction Transfection Frameshift Mutation Mutagenesis Protein Conformation Exons Structure-Activity Relationship Germ-Line Mutation src Homology Domains Phenotype Alleles Kinetics Sequence Deletion Protein Interaction Domains and Motifs Enzyme Activation Genes, erbB-1 Catalytic Domain Amino Acid Motifs Protein Structure, Secondary Dimerization Conserved Sequence Transcription, Genetic Mutation Rate Plasmids Heterozygote Cell Proliferation Protein Transport Substrate Specificity Genes, Dominant Gene Deletion Drug Resistance, Viral Gene Expression Regulation Polymorphism, Single-Stranded Conformational Gene Expression Promoter Regions, Genetic Apoptosis Genotype Catalysis Protein Multimerization Time Factors Cell Division Homozygote Gene Expression Regulation, Enzymologic Codon, Nonsense Protein Structure, Quaternary Protein Folding Protein Processing, Post-Translational Suppression, Genetic Dose-Response Relationship, Drug Codon Transcriptional Activation Cell Cycle Phylogeny Genes, Recessive Temperature Evolution, Molecular PDZ Domains Alternative Splicing Mutagenesis, Insertional Down-Regulation Sequence Homology, Nucleic Acid Molecular Weight Cell Survival

Disciplines and Occupations1

Immunohistochemistry

Information Science4

Molecular Sequence Data Amino Acid Sequence Base Sequence Phylogeny

Health Care2

Temperature Genetic Testing

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Benzamides Fusion Proteins, bcr-abl Leukemia, Myelogenous, Chronic, BCR-ABL Positive Piperazines Pyrimidines Mutation Protein Kinase Inhibitors Drug Resistance, Neoplasm Genes, abl Protein Structure, Tertiary Point Mutation Protein-Tyrosine Kinases DNA Mutational Analysis Thiazoles Mutation, Missense Receptor, Epidermal Growth Factor Phosphorylation Antineoplastic Agents Molecular Sequence Data Lung Neoplasms Protein-Serine-Threonine Kinases Amino Acid Sequence Protein Kinases Quinazolines Phosphatidylinositol 3-Kinases Amino Acid Substitution Protein Binding Base Sequence Mutagenesis, Site-Directed Sequence Homology, Amino Acid Binding Sites Cell Line, Tumor MAP Kinase Signaling System Models, Molecular Cell Line Signal Transduction Carcinoma, Non-Small-Cell Lung Recombinant Fusion Proteins Transfection Recombinant Proteins Sequence Alignment Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Frameshift Mutation Mutagenesis Protein Conformation Proto-Oncogene Proteins Exons Structure-Activity Relationship Cloning, Molecular Receptor Protein-Tyrosine Kinases Polymerase Chain Reaction Germ-Line Mutation src Homology Domains Protein Kinase C Phenotype Alleles Mutant Proteins Cyclic AMP-Dependent Protein Kinases Kinetics DNA-Binding Proteins Sequence Deletion p38 Mitogen-Activated Protein Kinases Protein Interaction Domains and Motifs DNA Primers p21-Activated Kinases Enzyme Activation Pedigree Mitogen-Activated Protein Kinase 1 Genes, erbB-1 Membrane Proteins Pyridazines Catalytic Domain Crystallography, X-Ray Mitogen-Activated Protein Kinase Kinases Transcription Factors Cell Membrane Tyrosine Amino Acid Motifs MAP Kinase Kinase Kinases Protein Structure, Secondary JNK Mitogen-Activated Protein Kinases Escherichia coli Carrier Proteins Mitogen-Activated Protein Kinase 3 Dimerization Ligands Proto-Oncogene Proteins c-kit RNA, Messenger Cyclin-Dependent Kinases Blotting, Western DNA DNA, Complementary eIF-2 Kinase Intracellular Signaling Peptides and Proteins Saccharomyces cerevisiae COS Cells Ribosomal Protein S6 Kinases Phosphotransferases (Alcohol Group Acceptor)Conserved Sequence

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