Kinase domain inactive enzyme activation. Medical search. Frequent questions

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Anatomy15

Cell Line Cell Membrane Cells, Cultured 3T3 Cells HeLa Cells Cell Line, Tumor Tumor Cells, Cultured Cytoplasm Muscles Cell Nucleus CHO Cells HEK293 Cells Brain Fibroblasts NIH 3T3 Cells

Organisms8

Escherichia coli Rabbits Desulfovibrio gigas Cattle Saccharomyces cerevisiae Cercopithecus aethiops Cricetinae Spodoptera

Diseases2

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cell Transformation, Neoplastic

Chemicals and Drugs147

Protein Kinases Recombinant Proteins Protein-Serine-Threonine Kinases Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Protein-Tyrosine Kinases Protein Kinase C Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Calmodulin Calcium Recombinant Fusion Proteins Phenylhydrazines Receptor Protein-Tyrosine Kinases Isoenzymes Cysteine Cyclic AMP-Dependent Protein Kinases Myosin-Light-Chain Kinase p38 Mitogen-Activated Protein Kinases p21-Activated Kinases Adenosine Triphosphate Mitogen-Activated Protein Kinase 1 Guanylate Cyclase Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases MAP Kinase Kinase Kinases Proto-Oncogene Proteins Potassium Cyanide Mitogen-Activated Protein Kinase 3 Tyrosine Enzyme Inhibitors Cyclin-Dependent Kinases eIF-2 Kinase Ribosomal Protein S6 Kinases Trypsinogen Type C Phospholipases Phosphotransferases (Alcohol Group Acceptor)DNA-Binding Proteins CDC2 Protein Kinase Creatine Kinase Adenylate Cyclase Casein Kinase II Intracellular Signaling Peptides and Proteins Macromolecular Substances Phosphoproteins Mitogen-Activated Protein Kinases Casein Kinases Membrane Proteins Receptor, Epidermal Growth Factor Diglycerides Ribosomal Protein S6 Kinases, 90-kDa MAP Kinase Kinase 1 Peptide Fragments Pyrimidines Pyruvate Kinase Enzyme Precursors DNA, Complementary MAP Kinase Kinase 4 Carrier Proteins DNA Primers 1-Phosphatidylinositol 4-Kinase Transcription Factors Serine Proto-Oncogene Proteins c-abl Extracellular Signal-Regulated MAP Kinases Magnesium Benzamides Thymidine Kinase Adaptor Proteins, Signal Transducing RNA, Messenger Calcium-Transporting ATPases Piperazines Aurora Kinases rho-Associated Kinases I-kappa B Kinase 3-Phosphoinositide-Dependent Protein Kinases Janus Kinase 2 Glycogen Synthase Kinase 3 Cell Cycle Proteins Phosphotyrosine CDC2-CDC28 Kinases Nucleoside-Phosphate Kinase Proto-Oncogene Proteins c-akt Protein Kinase C-alpha Nuclear Proteins Threonine DNA Protein Kinase C-delta Focal Adhesion Kinase 1 Fusion Proteins, bcr-abl AMP-Activated Protein Kinases Ligands Focal Adhesion Protein-Tyrosine Kinases Lim Kinases Phospholipids Diacylglycerol Kinase Peptides Nitric Oxide MAP Kinase Kinase Kinase 1 Guanylate Kinase Glutathione Transferase Bacterial Proteins Calcium-Calmodulin-Dependent Protein Kinase Type 2 Receptor, Insulin Tetradecanoylphorbol Acetate Drosophila Proteins Protein Isoforms Phosphofructokinase-2 Nitric Oxide Synthase Trans-Activators TOR Serine-Threonine Kinases Protein Kinase C-epsilon Staurosporine Fungal Proteins Phosphoserine Protein Kinase C beta MAP Kinase Kinase 6 Focal Adhesion Kinase 2 Androstadienes Cyclin-Dependent Kinase 2 Epidermal Growth Factor Antineoplastic Agents Cyclic GMP-Dependent Protein Kinases MAP Kinase Kinase 2 Phosphoglycerate Kinase Nerve Tissue Proteins Morpholines Phosphoprotein Phosphatases Actins Cyclin-Dependent Kinase 5 Phosphotransferases Cyclic AMP Indoles Janus Kinase 3 RNA, Small Interfering Chromones Proto-Oncogene Proteins pp60(c-src)Phosphothreonine Multienzyme Complexes Plant Proteins Janus Kinase 1 Pyridines Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Phosphorylase Kinase Arginine Kinase Arabidopsis Proteins Mutant Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Mutagenesis, Site-Directed Models, Molecular Cloning, Molecular Amino Acid Substitution Transfection Electrophoresis, Polyacrylamide Gel Crystallography, X-Ray Sequence Alignment Enzyme Stability Spectrophotometry Blotting, Western Two-Hybrid System Techniques Precipitin Tests Models, Biological Immunoblotting DNA Mutational Analysis Peptide Mapping Microscopy, Fluorescence Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction

Phenomena and Processes61

Enzyme Activation Kinetics Binding Sites Amino Acid Sequence Mutation Protein Binding Phosphorylation Catalysis Base Sequence Protein Conformation Substrate Specificity Sequence Homology, Amino Acid Catalytic Domain MAP Kinase Signaling System Protein Structure, Tertiary Structure-Activity Relationship Amino Acid Substitution Signal Transduction Transfection Hydrogen-Ion Concentration Oxidation-Reduction Molecular Weight src Homology Domains Protein Interaction Domains and Motifs Enzyme Stability Amino Acid Motifs Dimerization Protein Structure, Secondary Sequence Deletion Time Factors Hydrolysis Point Mutation Conserved Sequence Mutagenesis Protein Transport Transcription, Genetic Apoptosis Gene Expression Regulation Protein Multimerization Plasmids Mutation, Missense Cell Division Gene Expression Gene Expression Regulation, Enzymologic Protein Structure, Quaternary PDZ Domains Protein Processing, Post-Translational Phenotype Dose-Response Relationship, Drug Cell Cycle Protein Folding Promoter Regions, Genetic Cell Proliferation Drug Resistance, Neoplasm Transcriptional Activation Down-Regulation Gene Deletion Genes, abl Cell Adhesion Cell Survival Phylogeny

Information Science4

Molecular Sequence Data Amino Acid Sequence Base Sequence Phylogeny

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Enzyme Activation Kinetics Binding Sites Molecular Sequence Data Amino Acid Sequence Mutagenesis, Site-Directed Protein Kinases Mutation Protein Binding Recombinant Proteins Models, Molecular Protein-Serine-Threonine Kinases Phosphorylation Catalysis Base Sequence Phosphatidylinositol 3-Kinases Protein Conformation Cloning, Molecular Substrate Specificity Escherichia coli Sequence Homology, Amino Acid Catalytic Domain MAP Kinase Signaling System Protein Structure, Tertiary Protein Kinase Inhibitors Structure-Activity Relationship Protein-Tyrosine Kinases Amino Acid Substitution Protein Kinase C Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Calmodulin Signal Transduction Rabbits Transfection Electrophoresis, Polyacrylamide Gel Calcium Desulfovibrio gigas Hydrogen-Ion Concentration Cell Line Oxidation-Reduction Recombinant Fusion Proteins Phenylhydrazines Crystallography, X-Ray Receptor Protein-Tyrosine Kinases Molecular Weight Isoenzymes src Homology Domains Cysteine Cyclic AMP-Dependent Protein Kinases Myosin-Light-Chain Kinase p38 Mitogen-Activated Protein Kinases Cell Membrane p21-Activated Kinases Adenosine Triphosphate Mitogen-Activated Protein Kinase 1 Guanylate Cyclase Sequence Alignment Protein Interaction Domains and Motifs Mitogen-Activated Protein Kinase Kinases Enzyme Stability JNK Mitogen-Activated Protein Kinases MAP Kinase Kinase Kinases Proto-Oncogene Proteins Potassium Cyanide Cells, Cultured Mitogen-Activated Protein Kinase 3 Cattle Tyrosine Enzyme Inhibitors Cyclin-Dependent Kinases eIF-2 Kinase Ribosomal Protein S6 Kinases Trypsinogen Amino Acid Motifs Type C Phospholipases Dimerization Phosphotransferases (Alcohol Group Acceptor)DNA-Binding Proteins CDC2 Protein Kinase Creatine Kinase Adenylate Cyclase Protein Structure, Secondary Casein Kinase II Spectrophotometry Intracellular Signaling Peptides and Proteins Macromolecular Substances Phosphoproteins Mitogen-Activated Protein Kinases Casein Kinases Membrane Proteins Receptor, Epidermal Growth Factor Blotting, Western Diglycerides Ribosomal Protein S6 Kinases, 90-kDa Sequence Deletion MAP Kinase Kinase 1 Peptide Fragments Pyrimidines Pyruvate Kinase

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