Kinase cytokine receptor common beta subunit. Medical search. Frequent questions

The receptors for these cytokines contain extracellular Ig-like domains, similar to the IL-1 R family, but they have cytoplasmic domains with tyrosine kinase activity. (rndsystems.com)
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. (joplink.net)
This leads to homodimerization and activation of receptor associated tyrosine kinase (Janus Kinase 2). (bibf1120.com)
What are physical characteristics found in all tyrosine kinase receptors? (flashcardmachine.com)
How is the insulin tyrosine kinase receptor unusual? (flashcardmachine.com)
How is a tyrosine kinase receptor activated? (flashcardmachine.com)
It contains an intrinsic protein-tyrosine kinase activity. (rush.edu)

Interleukin-5 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
Several isoforms of the interleukin-5 receptor alpha subunit exist due to multiple ALTERNATIVE SPLICING. (harvard.edu)
This graph shows the total number of publications written about "Interleukin-5 Receptor alpha Subunit" by people in Harvard Catalyst Profiles by year, and whether "Interleukin-5 Receptor alpha Subunit" was a major or minor topic of these publication. (harvard.edu)
Below are the most recent publications written about "Interleukin-5 Receptor alpha Subunit" by people in Profiles. (harvard.edu)
Description: The MAR-1 monoclonal antibody reacts with the Fc epsilon Receptor I alpha subunit, an IgE-binding subunit lacking signal-transducing ability. (thermofisher.com)
The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. (cancer-genetics.org)

It is now known that a variety of light chain subunits (ANTIGENS, CD98 LIGHT CHAINS) can dimerize with the heavy chain. (wakehealth.edu)
The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). (edu.au)

Low affinity receptor for granulocyte-macrophage colony-stimulating factor. (cusabio.com)
Brines has proposed that Belinostat Epo mediates its neuroprotective effects via a heterodimeric EpoR made up of one EpoR and one common beta chain which is similar to the signal-transducing subunit shared by granulocyte-macrophage colony stimulating factor interleukin- 3 and interleukin-5 receptors (28). (bibf1120.com)

EpoR has an extracellular N-terminal domain a single hydrophobic transmembrane segment and a cytosolic domain with no intrinsic kinase activity (22 23 Epo binds to two adjacent EpoR on the cell surface. (bibf1120.com)
The integrin tails have no intrinsic kinase activity but rather serve as a site for the docking of various kinases and related adaptor proteins that comprise focal adhesions. (thno.org)
What is the most common activity found intrinsic to transmembrane receptors? (flashcardmachine.com)

Members of the common beta-chain family signal through heterodimeric receptor complexes that contain the common beta-chain subunit, while members of the common gamma-chain family signal through heterodimeric or heterotrimeric receptor complexes that contain the common gamma-chain subunit. (rndsystems.com)
Members of the IL-10 family cytokines have structural similarities and signal through heterodimeric receptor complexes with common subunits. (rndsystems.com)
However the role of the heterodimeric EpoR is quite controversial as some investigators have shown antiapoptotic and neuroprotective properties of the homodimeric EpoR (30) and others have shown that expression of Epo and EpoR track together while expression of the common beta chain is unrelated to either molecule (31). (bibf1120.com)
Integrins are heterodimeric, transmembrane receptors that function as mechanosensors, adhesion molecules and signal transduction platforms in a multitude of biological processes. (thno.org)
Integrins are heterodimeric cell surface receptors found in nearly all metazoan cell types, composed of non-covalently linked α and β subunits. (thno.org)

The gene that encodes the common gamma chain in these interleukin receptors is mutated in X-SCID. (wikipedia.org)

The four short-chain helix bundle cytokines that signal through class III receptor tyrosine kinases include M-CSF, SCF, Flt-3 Ligand, and IL-34, and are shown in columns four and five of the poster. (rndsystems.com)
Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. (joplink.net)
IL-6 exerts its action via a cell surface receptor which consists of two subunits, an 80 kDa ligand binding subunit (gp80) of 468 amino acids and a 130 kDa signal transducing protein (gp130) of 896 amino acid residues. (thermofisher.com)
Characterisation of the extracellular portion of the 80 kDa IL-6 receptor revealed the existence of a single immunoglobulin-like domain in the NH2-terminal of the extracellular region, which does not contribute to ligand binding. (thermofisher.com)
The remainder of the extracellular domain however is essential for low affinity ligand binding, which consecutively triggers the association of the receptor and gp130 thus forming a high affinity binding site for IL-6. (thermofisher.com)
So far, the soluble IL-6 receptor is unique in acting as an agonist together with its ligand. (thermofisher.com)
Integrins are not constitutively active but rather exist in multiple activation states wherein ligand binding stability is related to the activation status of the receptor. (thno.org)
How is a receptor-ligand binding curve determined? (flashcardmachine.com)
Describe the three lines on a receptor-ligand binding curve? (flashcardmachine.com)
These data provide the first evidence for ligand-dependent proteasomal degradation of the betac cytoplasmic domain, and they establish a novel mechanism for heterotypic desensitization of shared cytokine receptor signaling. (tamu.edu)
Programmed death ligand 1 (PD-L1), a mediator of the PD-1 receptor, plays an inhibitory role in cancer immune responses. (cancer-genetics.org)
Type I IFN receptor forms a ternary complex, composed of its two subunits IFNAR1 and IFNAR2, and a type I IFN ligand. (wikidoc.org)
Ligand binding to either subunit is required for and precedes dimerization and activation of the receptor. (wikidoc.org)
Each subunit of IFNAR contains an N-terminal ligand binding domain (with two or four fibronectin type II-like subdomains, for IFNAR2 and IFNAR1, respectively), a transmembrane (TM) domain, and a cytoplasmic domain. (wikidoc.org)
[7] Each type I IFN ligand contains a "hotspot", or a sequence of conserved amino acids that are involved in binding to the receptor, specifically the high affinity receptor IFNAR2, which determines the affinity of each ligand for the receptor. (wikidoc.org)
Structural analysis of type I IFN receptor with different type I IFN ligand subtypes revealed a similar binding site for the different agonists. (wikidoc.org)

A low affinity interleukin-5 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA SUBUNIT to form a high affinity receptor for INTERLEUKIN-5. (harvard.edu)
FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. (thermofisher.com)

Cytokines in the TNF superfamily bind to oligomeric, type I or type II transmembrane proteins that have multiple extracellular cysteine-rich domains. (rndsystems.com)
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). (edu.au)

Proteins in this family form homotrimers or in some cases, heterotrimers, and share a common extracellular domain known as the TNF homology domain (THD). (rndsystems.com)
Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. (joplink.net)
interaction( Hh) is a bound transfer that is very proteins in modifications resulting past plasma mRNA, fibril-associated information DNA, isoform kinase and activity( characterised in Hui and Angers, 2011). (evakoch.com)
Each domain consists of two antiparallel beta sheets and is folded topologically identically to single fibronectin type III domains from the extracellular matrix proteins tenascin and fibronectin. (embl.de)
download of been proteins appears the architectural subunit of including acids within enzymes and represents the inhibitor gene conjugation SSA to intracellular families that initiate dramatically synaptic from those short at the thyroid beta. (erik-mill.de)

For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. (joplink.net)
When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. (thermofisher.com)
Various cytokines, transcription factors, and other regulatory molecules have been found to be differentially methylated in CD8+ T cells in autoimmune diseases. (frontiersin.org)
When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation. (rush.edu)

A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. (childrensmercy.org)

qRT-PCR, Western blot and immunohistochemistry analysis were used to measure the expression of liver fibrosis and ductular reaction markers, inflammatory factors and BAs related metabolic transporters, along with nuclear receptor farnesoid X receptor (FXR). (bvsalud.org)
The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. (thermofisher.com)
IL-5, IL-3, and GM-CSF are hematopoietic cytokines that are key mediators of the allergic inflammatory response. (tamu.edu)
The activation, differentiation, and development of CD8+ T cells can be affected by numerous inflammatory cytokines, transcription factors, and chemokines. (frontiersin.org)
The activation, differentiation, and development of CD8+ T cells is accompanied by large-scale changes in the coordinated expression of numerous inflammatory cytokines, transcription factors (TFs) and chemokines that are correlated with their survival, effector function, and self-renewal ( 7 ). (frontiersin.org)
The mediators of the specific weight effect on the kidney appear to be an obesity-related inflammation, aggravated by a lowered anti-inflammatory adiponectin level, an increased oxidative stress and advanced glycation, and an enhanced TGF-beta expression, all of which might constitute promising therapeutic targets. (hindawi.com)

Herein, we demonstrate that agonistic ligation of these receptor subunits rapidly induces proteasomal degradation of the betac, but not the Ralpha, cytoplasmic domain, resulting in termination of signal transduction and yielding a truncated betac isoform ligated to the Ralpha subunit. (tamu.edu)
Proteasomal degradation of the betac cytoplasmic domain was also a prerequisite for endocytosis and lysosomal degradation of the ligated receptor subunits. (tamu.edu)

The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic receptors at the neuromuscular junction of skeletal muscles (see the image below). (medscape.com)
[ 1 , 2 ] Although the chief target of the autoimmune attack in most cases is the skeletal muscle nicotinic acetylcholine receptor (nAChR), other antigenic targets that are components of the neuromuscular junction (NMJ) have also been implicated. (medscape.com)
Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. (famri.org)

Receptor density is regulated by endocytosis of the cell surface receptor followed by lysosomal degradation (27). (bibf1120.com)

This gene encodes the interleukin receptor common gamma chain protein, which is a cytokine receptor sub-unit that is part of the receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. (wikipedia.org)
The gene IL2RG codes for the common gamma chain protein, which is a common subunit of the individual receptors for Interleukin 2, Interleukin 4, Interleukin 7, Interleukin 9, Interleukin 15 and Interleukin 21. (wikipedia.org)
The mutation can occur through large, or even single nucleotide, deletions in the IL2RG gene, that disable the common gamma chain so that it is unable to bind with other receptor subunits and signal cytokine activation. (wikipedia.org)
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. (thermofisher.com)
The protein encoded by this gene represents the beta subunit and is a type I membrane protein. (cancer-genetics.org)
The gene that codes for this cytokine is switched on in an infected cell, and the interferon synthesized and secreted to surrounding cells. (wikidoc.org)
This rat strain has the same hypertensive background as SHR but also a genetic mutation in the leptin receptor gene, which leads to hyperphagia with an attendant wide range of metabolic abnormalities, that is, high body weight, hyperglycemia, hyperlipidemia, and hyperinsulinemia. (hindawi.com)

The dsRNA acts like a trigger for the production of interferon (via Toll Like Receptor 3 ( TLR 3 ) a pattern recognition receptor of the innate immune system which leads to activation of the transcription factor IRF3 and late phase NF kappa Beta). (wikidoc.org)
Furthermore, interferon leads to upregulation of MHC I and therefore to increased presentation of viral peptides to cytotoxic CD8 T cells, as well as to a change in the proteasome (exchange of some beta subunits by b1i, b2i, b5i - then known as the immunoproteasome) which leads to increased production of MHC I compatible peptides. (wikidoc.org)
NMR structure of the interferon-binding ectodomain of the human interferon receptor. (wikidoc.org)
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. (wikidoc.org)

Epo signaling is later terminated by activation of phosphatases that dephosphorylate Janus Kinase 2 (25). (bibf1120.com)
The functions of APOE co-expressed genes were mainly enriched in adaptive immune response, protein-lipid complex subunit organization, actin cytoskeleton reorganization, cell chemotaxis, protein activation cascade and transcriptional misregulation in cancer. (jcancer.org)
The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). (thermofisher.com)
Risk factors for depression initiate an infection-like inflammation in the brain that involves activation microglial Toll-like receptors and glycogen synthase kinase-3β (GSK3β). (mdpi.com)
The short-term form cytokine( PCP) transcription acts the complexity of rate within the activation of a domain of targets. (erik-mill.de)

The Periodic Table of Cytokine and Chemokine Families poster includes members of the tumor necrosis factor (TNF) superfamily, and cytokines belonging to the different families of interleukins, interferons, and chemokines. (rndsystems.com)
As the most common endocrine tumor, PTC has a tendency to occur lymph node metastasis in the early stages of cancer, and 20%-30% of PTC patients already have cancerous lymph node involvement at the time of diagnosis [ 3 , 4 ]. (jcancer.org)
Receptors, Tumor Necrosis Factor, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
This graph shows the total number of publications written about "Receptors, Tumor Necrosis Factor, Type I" by people in this website by year, and whether "Receptors, Tumor Necrosis Factor, Type I" was a major or minor topic of these publications. (childrensmercy.org)
Below are the most recent publications written about "Receptors, Tumor Necrosis Factor, Type I" by people in Profiles. (childrensmercy.org)

Normal neuromuscular junction showing a presynaptic terminal with a motor nerve ending in an enlargement (bouton terminale): Synaptic cleft and postsynaptic membrane with multiple folds and embedded with several acetylcholine receptors. (medscape.com)

Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. (cancer-genetics.org)

Altered membrane events induced selective inhibition of TCR-induced phosphorylation of regulatory P85 subunit of PI3K and AKT as well as abrogated calcium influx. (nature.com)

Phosphoinositide 3-kinase (PI3K) signaling contributes to a variety of processes, mediating many aspects of cellular function, including nutrient uptake, anabolic reactions, cell growth, proliferation, and survival. (mdpi.com)

CONCLUSIONS: TAS exerted a hepatoprotective effect against CLF by ameliorating liver injury, inflammation and restoring the altered tau-BAs metabolism to produce a positive regulatory effect on FXR-related receptors and transporters. (bvsalud.org)

All IL-1 family members share a conserved beta-trefoil structure and bind to members of the IL-1 receptor (IL-1 R) family. (rndsystems.com)
These cytokines belong to the cysteine-knot superfamily and bind to members of the IL-17 receptor family. (rndsystems.com)
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. (cancer-genetics.org)
All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor ( IFNAR ) that consists of IFNAR1 and IFNAR2 chains. (wikidoc.org)

Within each square, the full name of the cytokine is listed, along with its alternate names, a symbol to signify its structure, and the receptors that it utilizes to activate downstream signaling. (rndsystems.com)

Signalling from these receptors normally promotes growth and differentiation of T-cells, B cells, natural killer cells, glial cells, and cells of the monocyte lineage, depending on the cell type and receptor activated. (wikipedia.org)
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. (thermofisher.com)
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. (thermofisher.com)

IFNAR is a heteromeric cell surface receptor composed of two subunits, referred to as the low affinity subunit, IFNAR1 , and the high affinity subunit, IFNAR2 . (wikidoc.org)
IFNAR1 is the low affinity subunit, originally cloned in 1990, and is composed of four fibronectin type II-like (FNII-like) subdomains, termed SD1-4. (wikidoc.org)

Additionally, it is shown whether each cytokine belongs to the beta-trefoil, four helix bundle, or cysteine-knot superfamily and their subfamily designation. (rndsystems.com)
Moving to the right, the next eight families shown in the poster belong to the four-helix bundle cytokine superfamily. (rndsystems.com)
This superfamily is further subdivided into the class I and class II cytokine receptor families. (rndsystems.com)
Belinostat models of hypoxia-ischemia it decreases neuronal and oligodendrocyte death and promotes neurogenesis angiogenesis and oligodendrogenesis (16 17 21 EpoR has a 66kDa protein component that belongs to the single chain cytokine type I receptor superfamily and confers Epo binding property (22). (bibf1120.com)

The mutation leads to an absent or abnormally functioning common gamma chain. (wikipedia.org)
The short-chain helical cytokine family includes members of the common gamma-chain and common beta-chain families of cytokines. (rndsystems.com)
In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. (joplink.net)
Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. (thermofisher.com)
The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. (cancer-genetics.org)

Below are the most recent publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in Profiles. (rush.edu)

The long-chain helical cytokine family includes the IL-6 family cytokines, G-CSF, erythropoietin, thrombopoietin, growth hormone, prolactin, and leptin, which are shown in columns five through eight of the poster. (rndsystems.com)

This activity describes the evaluation and management of patients with the most common manifestations of atopy and highlights the role of the interprofessional team in improving care for these patients. (clairegood.com)
This 55 kDa protein representing the extracellular portion of gp80 is generated by shedding, a process that seems to be controlled by protein kinase C. It is still functional, indicating that soluble gp80 plays a biological role in promoting IL-6 activity. (thermofisher.com)
Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. (famri.org)
SCID, or M activity, Slides in the receptor of two site secrets each with a important nucleolus shown of panels. (erik-mill.de)

Angiotensin II Activates Extracellular Signal Regulated Kinases via Protein Kinase C and Epidermal Growth Factor Receptor in Breast Cancer Cells," Journal of Cellular Physiology, Vol. 196, No. 2, 2003, pp. 370-377. (scirp.org)
In neurons other sites that are phosphorylated include activated phosphatidylinositol 3-kinase/akt rat sarcoma (Ras)/extracellular signal regulated kinase (ERK1/2) and nuclear factor- kappa-B (NF-κB) (25). (bibf1120.com)
The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. (thermofisher.com)
What are the six general types of signal transducer receptors? (flashcardmachine.com)
Moreover, proteasome-dependent termination of signaling induced by one betac-engaging cytokine resulted in cellular desensitization to signal transduction by subsequent stimulation with another betac-engaging cytokine. (tamu.edu)

Ligands for the class I cytokine receptor family include short-chain and long-chain helical cytokines. (rndsystems.com)
chain that inhibits cytokine signaling and exacerbates inflammation. (harvard.edu)
The receptors for these three cytokines consist of a cytokine-specific alpha (Ralpha) chain and a shared common beta (betac) chain. (tamu.edu)

IL-21R is a type-1 cytokine receptor and belongs to the IL-2R and IL-15R family. (intechopen.com)

As subunits enzyme is, the E bacillus hormones tested by the G1 and S enzymes, are involved and the ions of the invalid visitors are. (evakoch.com)

Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. (thermofisher.com)
The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. (thermofisher.com)

This is followed by viral infections such as pneumonitis, an inflammation of the lung which produces common symptoms such as cough, fever, chills, and shortness of breath. (wikipedia.org)
Mediators of the renoprotection, specifically linked to obesity and body weight control, include a reduced renal inflammation and TGF-beta expression, together with an enhanced level of adiponectin. (hindawi.com)

Ligands for the class II cytokine receptor family includes the IL-10 family cytokines, along with the type I, type II, and type III interferons, which are shown in columns three, four, and nine of the poster. (rndsystems.com)

Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion. (joplink.net)

We investigated whether expression of non-selective cation channels of the transient receptor potential canonical (TRPC) channel family are associated with proinflammatory cytokines in monocytes. (shengsci.com)

Furthermore, IL-21 promotes differential expression of many cytokines including interleukins and chemokines. (intechopen.com)

The final family of interleukins shown in the poster is the IL-17 family cytokines listed in column 10. (rndsystems.com)

Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signaling. (cusabio.com)
Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization. (tamu.edu)
Furthermore, while differential effects manifest after several days of chronic stimulation, changes to receptor structure, orientation, or stoichiometry have not elucidated the cause for differential signaling via different type I IFN subtypes. (wikidoc.org)

A juvenile or infantile type of pustular psoriasis has been described, but it is the least common form. (medscape.com)
Fibronectin type-III (FN3) repeats are both the largest and the most common of the fibronectin subdomains. (embl.de)
[8] The evolutionary conservation of type I IFN subtypes binding the same IFNAR receptor at the same site with differing affinities suggests that type I IFNs are nonredundant and potentially regulate different cellular responses. (wikidoc.org)

Interferons belong to the large class of glycoproteins known as cytokines . (wikidoc.org)

Both chains can be polymorphic although there is more structural variation in the beta chains. (edu.au)

Agency is provided by the study of of carcinogenesis associated with the treatment of invasive cervical cancer the role of cutaneous HPV types in important risk factors for two common by decreasing recurrences of cancerous skin carcinogenesis, carried out by the human cancers. (who.int)

Bae KM, Wang H, Jiang G, Chen MG, Lu L, Xiao L. Protein kinase C epsilon is overexpressed in primary human non-small cell lung cancers and functionally required for proliferation of non-small cell lung cancer cells in a p21/Cip1-dependent manner. (famri.org)

Diseases1

Chemicals and Drugs10

Tyrosine kinase7

Alpha subunit6

Antigens2

Granulocyte-macrop2

Intrinsic3

Heterodimeric5

Interleukin receptors1

Ligand16

Affinity receptor2

Transmembrane2

Proteins5

Molecules4

Specificity1

Inflammatory6

Cytoplasmic domain2

Nicotinic3

Lysosomal degradation1

Gene7

Interferon4

Activation5

Tumor5

Acetylcholine1

Endocytosis1

Phosphorylation1

PI3K1

Regulatory1

Bind4

Downstream1

Differentiation3

IFNAR12

Superfamily4

Gamma5

Colony-Stimul1

Erythropoietin1

Activity4

Signal5

Chain3

Belongs1

Enzymes1

Complex2

Inflammation2

Ligands1

Transcription1

Monocytes1

Chemokines1

Interleukins1

Signaling3

Type3

Glycoproteins1

Structural1

Risk Factors1

Cell1