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  • microvessels
  • Collectively, these results indicate that a large proportion of the microvessels encountered in the cortex of remnant kidneys are of lymphatic origin and cannot be discriminated by common endothelial markers, such as CD34, that are expressed by both lymphatic and blood endothelia cells. (asnjournals.org)
  • Two forms of gamma-glutamyltransferase from human brain cortex microvessels were partially purified by gel permeation and ion-exchange and group-affinity chromatography. (springer.com)
  • acute
  • siRNA directed to candidate genes, including p53, has prevented multiple forms of acute kidney injury (AKI) and renal fibrosis in animal models [ 10 - 14 ]. (hindawi.com)
  • Acute kidney injury (AKI) is a common clinical complication with uncertain outcome, ranging from complete restitution to high mortality. (hindawi.com)
  • MRNA
  • In mouse kidney cortex, si LRP2 reduced mRNA expression to 74.8 ± 6.3% 3 h and 70.1 ± 6.3% 6 h after administration. (hindawi.com)
  • In the kidney, siRNA stabilized with 2′O-methylation is filtered and reabsorbed in the renal proximal tubule (PT) following IV administration, reducing relative mRNA expression temporarily in the PT [ 9 ]. (hindawi.com)
  • membrane
  • Uptake of SO 4 2− into brush-border membrane vesicles isolated from rat kindey cortex by a Ca 2+ -precipitation method was investigated by using a rapid-filtration technique. (biochemj.org)
  • The experiments indicate the presence of an electroneutral Na + /SO 4 2− -co-transport system in brush-border membrane vesicles isolated from rat kidney cortex. (biochemj.org)
  • That is, the way the kidney absorbs water involves osmosis - the flow of pure solvent through a permeable membrane in the direction of the less concentrated solution to the more concentrated solution . (ndif.org)
  • Here these discrepant findings are addressed by reinvestigation of the vascularization of rat remnant kidneys by the use of two novel endothelial lineage specific, discriminatory markers, i.e. , the membrane mucoprotein podoplanin with specificity for lymphatic endothelia, and the glycosyl-phosphatidylinositol (GPI)-anchored membrane enzyme aminopeptidase P that is recognized by a monoclonal antibody designated JG12 and that is specifically expressed by endothelial cells of blood vessels only. (asnjournals.org)
  • left kidney
  • After 10 days, serum samples were collected for analysis, the left kidney was removed and assessed for calcium levels using flame spectroscopy, and the right kidney was sectioned for histopathological analysis using light microscopy. (nih.gov)
  • dose
  • Ultrastructural lesions were observed in cortex kidneys 24 h after irradiation at 2 and 4 Gy doses and 1 Gy/min dose rate, displaying all features of apoptotic process mainly in PCT isolated cells. (radioprotection.org)
  • blood
  • Due to the potential toxicity of maleic acid to the kidneys, this study aimed to develop an analytical method to investigate the pharmacokinetics of maleic acid in rat blood and kidney cortex. (mdpi.com)
  • The area under concentration versus time curve (AUC) of the maleic acid in kidney cortex was 5-fold higher than that in the blood after maleic acid administration (10 and 30 mg/kg, i.v., respectively), indicating that greater accumulation of maleic acid occurred in the rat kidney. (mdpi.com)
  • Tsai, T.-H. Pharmacokinetics of Maleic Acid as a Food Adulterant Determined by Microdialysis in Rat Blood and Kidney Cortex. (mdpi.com)
  • The prevailing intrarenal hormonal milieu and existing haemodynamic conditions also appear to strongly modulate these responses, indicating that multiple control systems interact to regulate regional kidney blood flow at an integrative level. (biomedsearch.com)
  • calcium
  • Nevertheless the exact mechanism of the preventive effects of these products is still far to be clearly established, being its knowledge necessary to successfully apply these therapies to avoid stone formation.This EG/AC-induced increase in kidney calcium levels was inhibited by the administration of lemon juice.These data suggest that lemon juice has a protective activity against urolithiasis. (nih.gov)
  • This EG/AC-induced increase in kidney calcium levels was inhibited by the administration of lemon juice. (nih.gov)
  • RT "A rat kidney-specific calcium transporter in the distal nephron. (genome.jp)
  • Administration
  • Ito K., Yamada K., Yoshida S., Hasunuma K., Tamura Y., Yoshida S. (1986) Endogenous Kallikrein Inhibitor in Rat Kidney Cortex-Effect of Glucocorticoid Administration. (springer.com)
  • Multiple microdialysis probes were simultaneously inserted into the jugular vein and the kidney cortex for sampling after maleic acid administration (10 or 30 mg/kg, i.v., respectively). (mdpi.com)
  • regulation
  • Consistent with this, the density of COX-2 - expressing cells in macula densa was significantly increased, indicating differential regulation of COX-2 in IM and cortex . (ndif.org)
  • expression
  • In ISOM and cortex , COX-1 expression was marginally reduced and mPGES expression was unaltered. (ndif.org)
  • COX-2 expression was undetected in ISOM and marginally increased in cortex . (ndif.org)
  • In the cortex , there were no changes in the expression of COX-1 and mPGES, whereas COX-2 expression was decreased. (ndif.org)
  • However, although COX-2 is not expressed in the normal gastric mucosa, there has now been definitive indication for localized and regulated COX-2 expression in the mammalian kidney. (asnjournals.org)
  • cells
  • As lymphatic endothelial cells secrete chemokines that attract dendritic cells, it is possible that the increase in lymphatic vascularization could enhance the immunologic surveillance of remnant kidneys. (asnjournals.org)
  • Note=Colocalized with S100A10 and CC ANAX2 along the apical domain of kidney distal tubular cells (By CC similarity). (genome.jp)
  • major
  • It was initially postulated that the major gastrointestinal and renal side effects of the original NSAID, termed "nonselective" because of their inhibition of both COX-1 and COX-2, would be avoided by the development of COX-2 selective NSAID, because COX-1 was recognized to be abundantly expressed in gastric mucosa and in kidney. (asnjournals.org)
  • physical
  • Comparison of the size and physical properties of γ-glutamyltranspeptidase purified from rat kidney following solubilization with papain or with Triton X-100. (springer.com)