This reaction is different from oxidative decarboxylation, which proceeds through a radical mechanism and is characterised by a different product distribution in isotopic labeling experiments with two different carboxylic acids. (wikipedia.org)
In organic chemistry, ketonic decarboxylation (also known as decarboxylative ketonization) is a type of organic reaction and a decarboxylation converting two equivalents of a carboxylic acid (R−C(=O)OH) to a symmetric ketone (R2C=O) by the application of heat. (wikipedia.org)
The initial formation of an intermediate carbanion via decarboxylation of one of the acid groups prior to the nucleophilic attack has been proposed, but is unlikely since the byproduct resulting from the carbanion's protonation by the acid has never been reported. (wikipedia.org)
Reaction5
The reaction mechanism likely involves nucleophilic attack of the alpha-carbon of one acid group on the other acid group's carbonyl (C=O), possibly as a concerted reaction with the decarboxylation. (wikipedia.org)
With two different carboxylic acids, the reaction behaves poorly because of poor selectivity except when one of the acids (for example, a small, volatile one) is used in large excess. (wikipedia.org)
Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO 2 ). (wikipedia.org)
These include Barton decarboxylation , Kolbe electrolysis , Kochi reaction , and Hunsdiecker reaction . (wikipedia.org)
Acids6
This reaction is different from oxidative decarboxylation, which proceeds through a radical mechanism and is characterised by a different product distribution in isotopic labeling experiments with two different carboxylic acids. (wikipedia.org)
With two different carboxylic acids, the reaction behaves poorly because of poor selectivity except when one of the acids (for example, a small, volatile one) is used in large excess. (wikipedia.org)
Hydrothermal experiments were undertaken to explore the reaction pathways of phenyl-containing carboxylic acids in the presence of iron oxide minerals. (azregents.edu)
Hydrothermal experiments with hydrocinnamic acid were performed to demonstrate the generality of the reaction pathways for carboxylic acids, although the rate of consumption of hydrocinnamic acid was slower than that of phenylacetic acid and yielded a complex variety of detected products. (azregents.edu)
These results indicate that minerals can enhance the complexity of organic product pathways for carboxylic acids and resulting products during hydrothermal transformations and may enable the production of hydrocarbons from organic acids and other precursors. (azregents.edu)