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  • synthesis
  • Compared with conventional chemical synthesis via ruthenium-catalyzed transfer hydrogenation or oxazaborolidine-catalyzed borane reduction [ 6 , 7 ], a biocatalyst-mediated reduction of 3,5-BTAP using microbial cells and various oxidoreductases has attracted more attention due to its excellent enantioselectivity, mild reaction conditions, few by-products and avoidance of residual metals. (biomedcentral.com)
  • Mice
  • Here we show that the infusion of the ketone body D -β-hydroxybutyrate (DβHB) in mice confers partial protection against dopaminergic neurodegeneration and motor deficits induced by MPTP. (jci.org)
  • metabolic
  • Ketone-Based Metabolic Therapy: Is Increased NAD+ a Primary Mechanism? (frontiersin.org)
  • In models of neurodegenerative diseases, metabolic therapy with a KD or analogous ketone-enhancing metabolic strategies have beneficial effects in cultured neurons, animal models, and in patients. (frontiersin.org)
  • In this review, we discuss how ketones serve discrete fine-tuning metabolic roles that optimize organ and organism performance in varying nutrient remains and protect from inflammation and injury in multiple organ systems. (chiropracticscientist.com)
  • Alternative
  • Alternative names: NAD+-beta-hydroxybutyrate dehydrogenase, hydroxybutyrate oxidoreductase, beta-hydroxybutyrate dehydrogenase, D-beta-hydroxybutyrate dehydrogenase, D-3-hydroxybutyrate dehydrogenase, D-(-)-3-hydroxybutyrate dehydrogenase, beta-hydroxybutyric acid dehydrogenase, -D-hydroxybutyrate dehydrogenase, and beta-hydroxybutyric dehydrogenase. (agrisera.com)