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  • Synonym
  • Synonym(s): 2-Oxoglutaric acid Formula: C5H6O5 Formula weight: 146.10 Purity: 98% CAS Number: 328-50-7 Harmonized Tariff Code: 2918.30 Hazard Statements: H315-H319-H335 Causes skin irritation. (thomassci.com)
  • Synonym(s): D-Arabino-2-hexulopyranosonic acid hemicalcium Salt, Calcium 2-keto-D-gluconate Formula: C6H9O7.1/2Ca H2O Formula weight: 231.22 Purity: 99% CAS Number: 3470-37-9 Harmonized Tariff Code: 2933.99 Hazard Statements: H315-H319-H335 Causes skin irritation. (thomassci.com)
  • amino acid seq
  • Its amino acid sequence is highly conserved in eukaryotes, differing by only a few residues. (wikipedia.org)
  • The projected amino acid sequence of the protein encoded by the GPR80 gene bore similarities to a purinergic receptor, P2Y1, and therefore might, like P2Y1, be a receptor for purine compounds. (wikipedia.org)
  • Shortly thereafter, a second report found this same gene, indicated that it coded for a G protein receptor with its amino acid sequence similarities closest to purinergic receptors GPR91 and P2Y1, and named the gene and its protein GPR99 and GPR99, respectively. (wikipedia.org)
  • organic
  • The reduction of ThPP levels causes dysfunction of the α-ketoglutarate dehydrogenase complex, which explains the high levels of this organic acid in MCPHA and suggests that mitochondrial ThPP transport is important for CNS development. (pnas.org)
  • synthase
  • Aureusidin synthase catalyses the aromatization and cyclization of the newly added carbonyl groups and facilitates the release of CoA to reform the carboxyllic acid. (wikipedia.org)
  • The compound is then treated with NADPH and dihydroflavinol 4-reductase to form leucopelargonidin, which is further oxidized with oxygen gas, alpha-Ketogluteratic acid, and anthocyanidin synthase. (wikipedia.org)
  • compound
  • The compound can be converted to α-ketoglutaric acid through the action of a 2-hydroxyglutarate dehydrogenase which, in humans, are two enzymes called D2HGDH and L2HGDH. (wikipedia.org)
  • reactions
  • Cytochrome c can also catalyze several redox reactions such as hydroxylation and aromatic oxidation , and shows peroxidase activity by oxidation of various electron donors such as 2,2-azino- bis (3-ethylbenzthiazoline-6-sulphonic acid) ( ABTS ), 2-keto-4-thiomethyl butyric acid and 4-aminoantipyrine. (wikipedia.org)
  • urea
  • In the more specific enzymatic methods, the enzyme urease converts urea to ammonia and carbonic acid. (wikipedia.org)
  • precursor
  • Asano H, Aonuma M, Sanosaka T, Kohyama J, Namihira M, Nakashima K. Astrocyte differentiation of neural precursor cells is enhanced by retinoic acid through a change in epigenetic modification. (springer.com)
  • gene
  • The Gene has recently been nominated as a receptor not only for 2-oxogluterate (see alpha-Ketoglutaric acid) but also for the three cysteinyl leukotrienes (CysLTs), particularly leukotriene E4 (LTE4) and to far lesser extents LTC4 and LTE4. (wikipedia.org)
  • form
  • First naringenin is reacted with two equivalents of oxygen gas, alpha-Ketogluteratic acid, and flavanone 3-hydroxylase to form dihydrokaempferol. (wikipedia.org)
  • enzyme
  • The dipole moment of cytochrome c is a result from a cluster of negatively charged amino acid side chains at the "back" of the enzyme. (wikipedia.org)
  • energy
  • An essential nucleotide triphosphate with a variety of roles in energy metabolism, signal transduction and nucleic acid metabolism. (thomassci.com)
  • brain
  • SLC25A19 mutations cause Amish lethal microcephaly (MCPHA), which markedly retards brain development and leads to α-ketoglutaric aciduria. (pnas.org)