• Kitabchi, A.E. and Nyenwi, E.A. (2006) Hyperglycemic crisis in diabetes mellitus: Diabetes ketoacidosis and hyperglycemic hyperosmolar state. (scirp.org)
  • Published May 16, 2013 at 675 × 558 in Hyperglycemic Crises: Diabetic Ketoacidosis And Hyperglycemic Hyperosmolar State . (endotext.org)
  • In acute diabetes conditions, management of the following 3 potential complications is required: diabetic ketoacidosis, hyperosmolar hyperglycemic state, and iatrogenic hypoglycemia. (aacnjournals.org)
  • Furthermore, a correct diagnosis can be difficult and delayed when ketoacidosis presents with unspecific symptoms, such as the picture of an "acute abdomen" ( 1 , 2 ). (frontiersin.org)
  • Diabetic ketoacidosis (DKA) is an acute complication of uncontrolled diabetes mellitus that is associated with increased morbidity and mortality. (lww.com)
  • Euglycemic diabetic ketoacidosis (EDKA) is a rare, acute, life-threatening emergency that is characterized by euglycemia, metabolic acidosis, and ketoacidosis. (uspharmacist.com)
  • Diabetic ketoacidosis (DKA) is an acute metabolic complication of diabetes characterized by hyperglycemia, hyperketonemia, and metabolic acidosis. (msdmanuals.com)
  • The objective of this manuscript is to review the clinical manifestations, diagnosis and management of diabetic ketoacidosis, one of the most common acute complications of diabetes mellitus. (edu.ng)
  • Emphasis was placed on clinical manifestations of diabetic ketoacidosis, its diagnosis and treatment.Diabetic ketoacidosis (DKA) is an acute complication of diabetes mellitus that can be life-threatening if not treated properly. (edu.ng)
  • Diabetic ketoacidosis (DKA) is an acute hyperglycemic emergency that occurs as a complication of diabetes. (i-sensusa.com)
  • We provisionally diagnosed diabetic ketoacidosis that was possibly precipitated by acute myocardial infarction, as there were findings in favor of (epigastric pain, electrocardiogram pattern, presence of 3 coronary heart disease risk factors) and against (young age, normal echocardiogram) the diagnosis of acute myocardial infarction. (biomedcentral.com)
  • A urine dipstick test detected ketones, bedside capillary testing using a glucometer showed high glucose concentrations, and arterial blood gas analysis indicated metabolic acidosis (pH = 7.16, carbon dioxide partial pressure = 13 mmHg, oxygen partial pressure = 123 mmHg, bicarbonate concentration = 4 mmol/L, base excess = -24 mmol/L). We provisionally diagnosed diabetic ketoacidosis, possibly precipitated by an acute myocardial infarction. (biomedcentral.com)
  • However, insufficient insulin administration may result in the development of hyperglycaemia leading to diabetic ketoacidosis (DKA) which, if not treated urgently, can progress to coma, acute kidney failure, cerebral injury or even death [ 4 ]. (biomedcentral.com)
  • Proper management of DKA requires hospitalization for aggressive intravenous fluids, insulin therapy, electrolyte replacement as well as identification and treatment of the underlying precipitating event along with frequent monitoring of patient's clinical and laboratory states. (lww.com)
  • ABSTRACT This study described the profile of 100 cases of diabetic ketoacidosis (DKA) at a teaching hospital in Benghazi, Libyan Arab Jamahiriya. (who.int)
  • Study aimed to determine the rate and prediction of infection in diabetes mellitus patients ≥18 year, with diabetic ketoacidosis (DKA). (scirp.org)
  • Slovis, C.M., Mork, V.G., Slovis, R.J. and Bain, R.P. (1987) Diabetes ketoacidosis and infection: Leukocyte count and differential as early predictors of serious infection. (scirp.org)
  • According to this literature research risk factors for the development are infection, perioperative fasting, surgical stress, and insulin dose reduction. (frontiersin.org)
  • A person may have laboratory values identical to a "normal" hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly. (wikipedia.org)
  • 5 The use of corticosteroids, 6 -agonists and high incidence of urinary tract infection have also been shown to precipitate DKA in pregnancy. (bmj.com)
  • COVID19 infection is associated with worse outcomes in patients admitted with diabetic ketoacidosis (DKA). (jdeponline.com)
  • a precipitating factor (eg infection, stress) which causes an excess of stress hormones (which antagonise the actions of insulin) may be present. (litfl.com)
  • Diabetic ketoacidosis can be the initial presentation of diabetes mellitus or precipitated in known patients with diabetes mellitus by many factors, most commonly infection. (edu.ng)
  • to be applied?APRICOT : AIDS Pegasys Ribavirin International CO-infection Trial?APSAC: Anisolyated plasminogen streptokinase activator complex?APT: Alum-precipitated toxoid?aPTT: Activated partial thromboplastin time?APTT: Activated partial thromboplastin time?aq. (kuwaitpharmacy.com)
  • Various factors can precipitate DKA, including 1) lack of insulin 2) use of certain prescription or illicit drugs, and 3) physiological stressors such as infection that increase the need for insulin. (i-sensusa.com)
  • The common leading precipitating factors for DKA in our study were psycho-social causes and infection which observed in 49%, and 31% respectively. (ejpmr.com)
  • While new-onset diabetes and infection are recognized precipitating causes for DKA, insulin omission related to finances, mental health, and social determinants should be identified, and patients directed to appropriate resources, said experts previewing the upcoming new report at the European Association for the Study of Diabetes (EASD) annual meeting. (medscape.com)
  • Universal sampling technique was employed for data collection among Diabetes ketoacidosis patients, over a period of 3 years (Jan 2008-Dec 2010). (scirp.org)
  • Charfen, M.A. and Fernandez, F.M. (2005) Diabetes ketoacidosis. (scirp.org)
  • Diabetic ketoacidosis (DKA) is a potentially life-threatening condition and sometimes hard to identify when other seemingly related parameters, such as hyperglycemia, are missing. (frontiersin.org)
  • DKA, a life-threatening complication of diabetes, is characterized by the triad of hyperglycemia, metabolic acidosis, and ketoacidosis. (uspharmacist.com)
  • Diabetic Ketoacidosis (DKA) is a rare complication of diabetic pregnancy and usually associated with underlying Type 1 diabetes. (bmj.com)
  • One possible reason for increased mortality due to SARS-CoV-2 in patients with diabetes is from the complication of diabetic ketoacidosis (DKA). (biomedcentral.com)
  • Besides urinary tract and genital infections, one major adverse effect is the so-called euglycemic diabetic ketoacidosis (EDKA), which requires close attention ( 22 - 24 ). (frontiersin.org)
  • The most common precipitating causes for DKA include infections, new diagnosis of diabetes and nonadherence to insulin therapy. (lww.com)
  • Although there are multiple precipitating causes, underlying infections are the most common. (bvsalud.org)
  • 7 DKA in pregnancy is most likely to be precipitated by infections, starvation, insulin non-compliance, and hyperemesis gravidarum (a severe form of nausea and vomiting). (i-sensusa.com)
  • Unlike DKA, the patient with HHNS does not develop ketoacidosis. (ems1.com)
  • In 1940, Dillon and colleagues first described alcoholic ketoacidosis (AKA) as a distinct syndrome. (medscape.com)
  • The diagnosis of alcoholic ketoacidosis (AKA) requires arterial blood gas (ABG) measurement and serum chemistry assays. (medscape.com)
  • involves an absolute or relative lack of insulin leads to diabetic metabolic decompensation with hyperglycaemia and ketoacidosis. (litfl.com)
  • Newfoundland and Labrador (NL) has a very high incidence of type 1 diabetes (T1DM) and admission rate for diabetic ketoacidosis (DKA). (biomedcentral.com)
  • Among children diagnosed with T1DM, diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality [ 5 ]. (biomedcentral.com)
  • Understanding the factors associated with the development of DKA in the pediatric population is vital in order to prevent DKA, especially in a region with a very high incidence of T1DM and DKA admissions. (biomedcentral.com)
  • [4] In addition, delay in presentation of children with Type 1 diabetes mellitus (T1DM) with increased frequency of severe diabetic ketoacidosis (DKA) at presentation has been reported. (jdeponline.com)
  • This article reviews the pathogenesis, precipitating or risk factors, diagnosis or identification, and treatment of these critical complications of diabetes. (aacnjournals.org)
  • In those with established diabetes, insulin omission, whether deliberate or unintentional, is the most common precipitating factor for DKA. (biomedcentral.com)
  • 9 The increase in glucagon and decrease in insulin shift the metabolism toward lipolysis, an increase in free fatty acids (FFAs), and ketoacidosis. (uspharmacist.com)
  • Euglycemic diabetic ketoacidosis (EDKA) is a potentially life-threatening condition and a reported side effect of antidiabetic sodium-glucose-cotransporter-2-inhibitors (SGLT2-I). The analysis of the herein presented case and its management formed the incentive to prepare this multidisciplinary work and includes an overview about perioperative SGLT2-I-induced ketoacidosis. (frontiersin.org)
  • 1 Other factors that can contribute to EDKA are 1) the decrease in hepatic glucose production during a fasting state when glycogen stores are already depleted and 2) the increased urinary excretion of glucose. (uspharmacist.com)
  • Factors that stress the body, such as trauma or burns, will trigger a stress-response, releasing a number of hormones (epinephrine, cortisol, and glucagon) that have a tendency to counter the effects of insulin and raise the blood glucose level. (ems1.com)
  • The leukemic process may play some role in glucose homeostasis and may be considered as a precipitating factor for DKA. (tmu.edu.tw)
  • Case of ketoacidosis by a sodium-glucose cotransporter 2 inhibitor in a diabetic patient with a low-carbohydrate diet. (bjd-abcd.com)
  • Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. (bjd-abcd.com)
  • 1, 5 Obesity in adulthood is recognised as an independent risk factor for the development of type 2 diabetes, and obesity in adolescence increases the risk of insulin resistance and glucose intolerance. (bmj.com)
  • An upcoming joint society statement on hyperglycemic emergencies in adults with diabetes will de-emphasize glucose from the diagnostic criteria for diabetic ketoacidosis (DKA), along with many other updates to the last statement on the topic, published 14 years ago. (medscape.com)
  • however, approximately 2.6% to 3.2% of DKA admissions are cases of EDKA, in which metabolic acidosis and ketoacidosis are accompanied by euglycemia. (uspharmacist.com)
  • Our study aimed to explore healthcare professionals' perceptions of factors affecting presentation of people with type 1 diabetes in a low socioeconomic area of Queensland, Australia. (biomedcentral.com)
  • Gaps in support for patient self-care to avoid diabetic ketoacidosis presentations and prevent late presentation of diabetic ketoacidosis revealed by this study require service reconfiguration to support care delivery. (biomedcentral.com)
  • Diabetic ketoacidosis (DKA) is the most common hyperglycemic emergency and causes the greatest risk for death in patients with diabetes mellitus. (lww.com)
  • Increased intestinal permeability as a risk factor for type 2 diabetes. (nih.gov)
  • Diabetic ketoacidosis (DKA) occurs in patients with type 1 diabetes mellitus and is less common in those with type 2 diabetes. (msdmanuals.com)
  • Diabetes is an independent risk factor for heart failure (HF), with current trends indicating that nearly half of patients with type 2 diabetes will develop this complication. (diabetesjournals.org)
  • There have been reports of several cases of ketoacidosis, mostly euglycaemic, and in people with type 1 or type 2 diabetes. (bjd-abcd.com)
  • Once thought to occur only in patients with type 1 diabetes, diabetic ketoacidosis has also been observed in patients with type 2 diabetes under certain conditions. (edu.ng)
  • The management of diabetic ketoacidosis involves careful clinical evaluation, correction of metabolic abnormalities, identification and treatment of precipitating and co-morbid conditions, appropriate long-term treatment of diabetes, and plans to prevent recurrence. (edu.ng)
  • The disease process begins months to years before the onset of clinical signs such as polyuria, polydipsia, weight loss, and diabetic ketoacidosis. (wikidoc.org)
  • Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. (jhsmr.org)
  • Diabetic ketoacidosis is best classified through the presence of ketones that exist in the liver, which are directly correlated to the lack of insulin being produced in the body. (diabetestalk.net)
  • 4 However, euglycemic diabetic ketoacidosis (EDKA) has emerged as a rare but serious adverse effect associated with SGLT2i. (uspharmacist.com)
  • 5,6 Pharmacists should be well versed in EDKA and its precipitating factors in order to educate patients and clinicians on the signs and management of EDKA in patients taking SGLT2i. (uspharmacist.com)
  • She had no risk factors for diabetes, no family history of diabetes and normal body mass index. (bmj.com)
  • Her coronary heart disease risk factors apart from diabetes included hypercholesterolemia and smoking. (biomedcentral.com)
  • Regarding coronary risk factors, apart from diabetes and hypercholesterolemia, she was a smoker of more than two packs of cigarettes daily. (biomedcentral.com)
  • Various precipitating factors have been reported in 25-30% of pituitary apoplexy patients. (nel.edu)
  • Differences were considered makes patients prone to ketoacidosis. (who.int)
  • Diagnosis of diabetes in new patients and issues related to interrupted insulin delivery in pre-existing patients using insulin pump therapy were the most common factors associated with DKA. (biomedcentral.com)
  • Les patients étaient inclus en accord avec les critères de consensus internationaux. (bvsalud.org)
  • Elle a mis en exergue l'intérêt de la réorganisation de la prise en charge de ces patients en période de crise sanitaire, l'éducation thérapeutique des patients et le recours à la télémédecine pour assurer la continuité des soins. (bvsalud.org)
  • and critically ill patients are at increased risk for developing hypophosphatemia due to the presence of multiple causal factors. (biomedcentral.com)
  • Hypophosphatemia is one of those frequently encountered electrolyte disorders, for which many causative factors are present in critically ill patients. (biomedcentral.com)
  • The purpose of this study was to identify characteristics and precipitating factors associated with pediatric DKA in this population. (biomedcentral.com)
  • We performed a medline search of the English-language literature using a combination of words (diabetic ketoacidosis, hyperglycemic crises) to identify original studies, consensus statements and reviews on diabetic ketoacidosis published in the past 15 years. (edu.ng)
  • Ear drops?AutoPap: Computer-assisted cytology interpretation system?AV: Aortic valve?AV: Atrioventricular?A-V: Arteriovenous?AVERT: Atorvastatin Versus Revascularization treatment?AVID: ?AVM: Arteriovenous Malformation?AVNRT: AV nodal reentry tachycardia?AVP: Arginine vasopressin?AVR: Aortic valve replacement?AVR: Augmented V lead, right arm (ECG)?AVRT: ?AVS: Arteriovenous shunt?AWS: Alcohol withdrawal syndrome?AXR: Abdominal X ray?AZF: Azoospermia factor genes?AZT: Azidothymidine (zidovudine)?B & O: Belladonna and opium?B Bx. (kuwaitpharmacy.com)
  • Foster, D.W. and MacGarry, J.D. (1983) The metabolic derangement and treatment of diabetic ketoacidosis. (scirp.org)
  • A total of 33 articles on SGLT2-I-induced ketoacidosis in the context of surgical treatment were identified. (frontiersin.org)
  • Diabetic ketoacidosis (DKA) and pancreatic pseudocysts are rare complications following treatment of hematological malignancies with L-asparaginase (L-asp). (tmu.edu.tw)
  • Diabetic Ketoacidosis: Evaluation and Treatment. (i-sensusa.com)
  • The goal of management is to avoid precipitating factors in cases of suspected porphyrias. (medscape.com)
  • 1 In the presence of a carbohydrate deficit due to precipitating factors, there is a reduction in serum insulin and an excess of glucagon, epinephrine, and cortisol. (uspharmacist.com)
  • this poses a theoretical risk for ketoacidosis (including euglycaemic ketoacidosis) in the presence of other precipitating factors, especially reduction in insulin doses or low carbohydrate intake. (bjd-abcd.com)
  • Diabetes mellitus (DM) itself is a well-established risk factor and/or comorbidity for several pathologies seen in surgical wards, such as gastrointestinal malignancy, abdominal, and/or peripheral artery disease, likely with amputation and obesity with bariatric surgery ( 6 - 8 ). (frontiersin.org)