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  • The FDA approved ketamine (Ketalar) in 1970. (drugbank.com)
  • Ketamine sold under the brand name Ketalar among others is a medication mainly used for starting and maintaining anesthesia. (ketamine-supplier.com)
  • The distinctive characteristics of Ketamine anesthesia are preserved breathing and airway reflexes and stimulated heart function with heightened blood pressure. (google.com)
  • Ketamine can be used for induction of anesthesia prior other general anesthetic agents and as a supplement of low potency agents. (pharmfair.com)
  • It may take you longer to recover from anesthesia with ketamine if you have recently used a barbiturate such as phenobarbital (Luminal) or secobarbital (Seconal), or a narcotic medication such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin), oxycodone (OxyContin), propoxyphene (Darvocet, Darvon), and others. (stimuworldchem.com)
  • Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. (wikipedia.org)
  • At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia. (wikipedia.org)
  • The use of ketamine in anesthesia reflects its characteristics. (wikipedia.org)
  • Protective airway reflexes are preserved and it is sometimes possible to administer ketamine anesthesia without protective measures to the airways. (wikipedia.org)
  • Ketamine is an option in children, as the sole anesthetic for minor procedures or as an induction agent followed by neuromuscular blocker and tracheal intubation In particular, children with cyanotic heart disease and neuromuscular disorders are good candidates for ketamine anesthesia. (wikipedia.org)
  • Due to the bronchodilating properties of ketamine, it can be used for anesthesia in people with asthma, chronic obstructive airway disease, and with severe reactive airway disease including active bronchospasm. (wikipedia.org)
  • Operative anesthesia was induced with intravenous administration of 6.0 mg ketamine hydrochloride per kg bodyweight (Ketaved? (exposed-skin-care.net)
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  • Ketamine is a NMDA receptor antagonist used as anesthetic agent. (seqens.com)
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  • Ketamine interacts with N-methyl-D-aspartate (NMDA) receptors, opioid receptors, monoaminergic receptors, muscarinic receptors and voltage sensitive Ca ion channels. (pharmfair.com)
  • Ketamine is an NMDA receptor pore blocker and that accounts for most of its actions, except the antidepressant effect, the mechanism of which is a matter of much research and debate. (wikipedia.org)
  • Ketamine, a dissociative anesthetic commonly used in pediatrics, and MK-801/Dizocilpine, a potent N-methyl-D-aspartate (NMDA) receptor antagonist commonly used for research purposes, are structural analogues of PCP that possess varying degrees of adverse clinical effects. (medscape.com)
  • Esketamine, the S-enantiomer of racemic ketamine, is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor. (drugbank.com)
  • ketamine hcl (Ketamine hydrochloride) is a nonbarbiturate anesthetic chemically designated (±)-2-(o-Chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. (stimuworldchem.com)
  • 2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone (Ketamine) is a tranquilizer, analgesic, and dissociative anesthetic commonly used in pediatrics and surgery for procedural sedations, as well as in veterinary medicine. (medscape.com)
  • Ketamine is manufactured commercially as a powder or liquid. (whatisketamine.com)
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  • A 2011 clinical practice guideline supports the use of ketamine as a sedative in emergency medicine, including during physically painful procedures. (wikipedia.org)
  • Ketamine hydrochloride is a quick-acting anesthetic that is legally used in both humans (as a sedative for minor surgery) and animals (as a tranquilizer). (kidshealth.org)
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  • We captured 10 free-ranging desert mule deer ( Odocoileus hemionus crooki ) (five males and five females) by net-gun from a helicopter and immobilized them with xylazine hydrochloride (HCl) (100 mg) and ketamine HCl (300 to 400 mg) injected intramuscularly. (bioone.org)
  • Captive deer permitted to recover from xylazine HCl-ketamine HCl immobilization without a reversal agent were able to walk in 290 ± 79 min. (bioone.org)
  • Recordings were obtained in pups anesthetized with the injectable mix of ketamine/xylazine (K/X mix), with the volatile anesthetic isoflurane (ISO), or in pups anesthetized with K/X mix that were also exposed to ISO. (frontiersin.org)
  • Following sedation with IM ketamine/xylazine, mydriasis was induced with topical 1% tropicamide hydrochloride. (cdc.gov)
  • Ketamine is a fast-acting anesthetic and painkiller used primarily in veterinary surgery. (google.com)
  • Veterinary clinics have been robbed for their ketamine supply, and ketamine supplies have been diverted from pharmacies in Mexico. (higheredcenter.org)
  • It is formulated as a slightly acid (pH 3.5 to 5.5) sterile solution for intravenous or intramuscular injection in concentrations containing the equivalent of 50 mg ketamine base per milliliter and contains not more than 0.1 mg/mL benzethonium chloride added as a preservative. (stimuworldchem.com)
  • For chronic pain, ketamine is used as an intravenous analgesic, particularly, if the pain is neuropathic. (wikipedia.org)
  • As with GHB and rohypnol, ketamine has been used as a so-called date rape drug due to anesthetic and dissociative effects. (higheredcenter.org)
  • Ketamine users can experience a dissociative state, resulting in out-of-body or near-death experiences. (higheredcenter.org)
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  • Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. (pharmfair.com)
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  • Ketamine is an animal tranquilizer that can knock you out, and leave you unconscious and vulnerable. (abovetheinfluence.com)
  • Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes. (wikipedia.org)
  • Since 1965, the recreational use of ketamine has increased and it became very popular during the 1990s among young adults at dance clubs and raves in combination with other so-called "club drugs" (eg, gamma-hydroxybutyric acid, lysergic acid diethylamide [LSD], ecstasy). (medscape.com)
  • Even with recreational use, ketamine can cause incapacitation, leaving users vulnerable and prone to amnesia. (higheredcenter.org)
  • Wester accessed the controlled substances box inside a locked safe located on board an emergency helicopter, removed ketamine from two vials, and replaced the removed ketamine with saline, knowing that the ketamine was intended to be administered via injection to critically ill and injured patients being transported by helicopter for emergency treatment. (fda.gov)
  • On August 30, 2018, a special agent with the Food and Drug Administration (FDA)'s Office of Criminal Investigations interviewed Wester, who admitted to removing ketamine from two vials on August 26. (fda.gov)
  • Later that evening, Wester went out to the helicopter, withdrew the ketamine from two vials, and replaced it with saline. (fda.gov)
  • Ketamine Hydrochloride belongs to a class of drugs called General Anesthetics, Systemic. (safemedicalpills.com)
  • The effect of ketamine on the respiratory and circulatory systems is different from that of other anesthetics. (wikipedia.org)
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  • Ketamine is a novel compound that was derived from phencyclidine in 1962, in pursuit of a safer anesthetic with fewer hallucinogenic effects. (wikipedia.org)
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  • Regarding mutagenesis and fertility, ketamine showed to be clastogenic and to not have effects on fertility. (pharmfair.com)
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  • Two placebo-controlled studies were performed to evaluate the effects of ketamine on the ability to drive. (drugbank.com)
  • With its fast-acting and long-lasting effects, ketamine can render an unknowing victim unconscious and unable to resist sexual assault. (higheredcenter.org)
  • With a high lasting from one to six hours, ketamine can leave residual effects in users lasting as long as two days. (higheredcenter.org)
  • Ketamine infusions are used for acute pain treatment in emergency departments and in the perioperative period in individuals with refractory pain. (wikipedia.org)
  • In multiple clinical trials, ketamine infusions delivered short-term pain relief in neuropathic pain diagnoses, pain after traumatic spine injury, fibromyalgia, and complex regional pain syndrome (CRPS). (wikipedia.org)
  • L1336, FDA label] Reports have indicated a potential use of ketamine as a therapeutic tool for the management of depression when administered in lower doses. (pharmfair.com)
  • At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression. (wikipedia.org)
  • When used at anesthetic doses, ketamine usually stimulates rather than depresses the circulatory system. (wikipedia.org)
  • Using ketamine can cause profound physical and mental problems, including impaired learning ability and memory, amnesia and potentially fatal respiratory problems. (abovetheinfluence.com)
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  • For inhalation, the powdered hydrochloride salt is converted into a more volatile form, usually by adding sodium bicarbonate , water, and heat. (msdmanuals.com)
  • Adjunctive to morphine or on its own, ketamine reduces morphine use, pain level, nausea, and vomiting after surgery. (wikipedia.org)
  • However, to prevent unwanted motion blurring of the radiograph or accidental induction of trauma to the restive animal, and to protect the radiographer, it is advisable to sedate the birds by i.v. injection of ketamine-HCL, or better, to anaesthetize the birds using inhalation anaesthesia with isoflurane . (vin.com)
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  • Ketamine is a mixture of two enantiomers (mirror image molecules). (drugbank.com)
  • As ketamine is sometimes sold in a mixture with other drugs or misrepresented as ecstasy, users also risk unknowingly ingesting the drug, or being unaware of how the drug may affect them. (higheredcenter.org)
  • This stable-labeled internal standard is suitable for quantitation of ketamine levels in GC/MS or LC/MS applications from clinical toxicology and forensic analysis to urine drug testing and isotope dilution methods. (fishersci.com)
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  • KETAMINE is now considered a dangerous drug. (tsikot.com)
  • Philippine Drug Enforcement Agency chair Anselmo S. Avenido, Jr. made this clarification in reaction to a People's Journal report that drug syndicates are producing ketamine here for export abroad. (tsikot.com)
  • The DDB reclassified ketamine as a dangerous drug upon the recommendation of the PDEA. (tsikot.com)
  • Ketamine is especially useful in the prehospital setting, due to its effectiveness and low risk of respiratory depression. (wikipedia.org)
  • A31873] These reports have increased the interest for ketamine in this area and several clinical trials are launched for this indication. (pharmfair.com)
  • Low blood pressure is dangerous for people with severe head injury and ketamine is unlikely to lower blood pressure - conversely, often raising blood pressure, making it often the best suited for those with severe head injury. (wikipedia.org)
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  • The Dangerous Drugs Board included ketamine in the list of dangerous drugs, making its possession, unless authorized by the agency, illegal. (tsikot.com)
  • On August 26, 2018, Wester, with reckless disregard for the risk that another person would be placed in danger of death and bodily injury, and under circumstances manifesting extreme indifference to such risk, tampered with ketamine hydrochloride (ketamine), a consumer product that was manufactured outside of Alabama and affected interstate commerce. (fda.gov)
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