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  • KRT7
  • Here we use luciferase reporter assays to analyze the tissue-specific regulatory elements of murine keratin 7 (Krt7) promoter in vitro and in vivo. (dundee.ac.uk)
  • genes
  • Keratin 6A and keratin 6B are encoded by the neighbouring genes, which are identical in intron-exon organization to KRT6C and are more than 99% identical in their DNA coding sequences. (wikipedia.org)
  • The human genome encodes 54 functional keratin genes which are located in two clusters on chromosomes 12 and 17. (wikipedia.org)
  • Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations. (wikipedia.org)
  • Duplication and divergence events then led to claw β-keratin genes, and further recombination resulted in new feather and feather-like avian β-keratin genes. (wikipedia.org)
  • A recent study using molecular dating methods to link the evolution of avian β-keratin genes in general to that of feathers specifically reveals that the avian β-keratin family began diverging from the crocodile family about 216 million years ago. (wikipedia.org)
  • antigen
  • Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively. (wikipedia.org)
  • coiled-coil
  • The major force that keeps the coiled-coil structure is hydrophobic interactions between apolar residues along the keratins helical segments. (wikipedia.org)
  • proteins
  • The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. (wikipedia.org)
  • Keratins are generally expressed in particular pairs of type I and type II keratin proteins in a tissue-specific and cellular differentiation-specific manner. (wikipedia.org)
  • Keratin (/ˈkɛrətɪn/) is one of a family of fibrous structural proteins. (wikipedia.org)
  • Their mechanism of action is dominant negative interference, with the mutated keratin proteins interfering with the structure and integrity of the cytoskeleton. (wikipedia.org)
  • Fibrous
  • Fibrous keratin molecules supercoil to form a very stable, left-handed superhelical motif to multimerise, forming filaments consisting of multiple copies of the keratin monomer. (wikipedia.org)
  • Reactivity
  • Beta-Keratin Specific Immunological reactivity in Feather-Like Structures of the Cretaceous Alvarezsaurid, Shuvuuia deserti Journal of Experimental Biology (Mol Dev Evol) 255:146-157 beta-Keratins at the US National Library of Medicine Medical Subject Headings (MeSH) There are two main forms of keratin, alpha-keratin and beta-keratin. (wikipedia.org)
  • helical
  • This model has been confirmed by the determination of the crystal structure of a helical domain of keratins. (wikipedia.org)
  • Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins. (wikipedia.org)
  • protein structure
  • Trichocyte keratins are similar in their gene and protein structure to keratins except that they are especially rich in the sulfur-containing amino acid cysteine, which facilitates chemical cross-linking of the assembled hard keratins to form a more structurally resilient material. (wikipedia.org)
  • hair
  • Keratin treatment and color-safe - Signature blend of Watermelon, Lychee and Edelweiss Flower Extracts combats the effects of environmental stressors - Free from parabens and sodium chloride - 250ml also available -Instructions for use: - Shake well - Spray evenly from root to tip and tousle hair - Add heat for extra volume - 75ml/ 2oz. (shopstyle.ca)
  • Safe for color and keratin-treated hair - Free from parabens and sodium chloride - Provides UV protection for hair -Instructions for use: - Shake well before use - Apply product onto damp hair and diffuse or simply air-dry - 175ml/ 5.7oz. (shopstyle.ca)
  • Hydrolyzed Wheat Protein and Pro-Vitamin B5 create texture and light hold - Paraben and Sodium Chloride-free, UV protection - Keratin treatment and color-safe - Also available in 300ml -Instructions for use: - Shake bottle - Spray on wet or dry hair - Tousle with fingers and leave to air dry - 75ml/ 2.2fl.oz. (shopstyle.ca)
  • This reduces the tensile strength of the keratin so greatly that the hair can be wiped away. (wikipedia.org)
  • The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. (wikipedia.org)
  • this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. (wikipedia.org)
  • The fungi can also spread to hair, grow inside hair strands, and feed on the keratin within hair, including the hair on the feet, the hair of one's beard, and the hair on one's head. (wikipedia.org)