• The hallmarks of diabetic cardiomyopathy, in experimental or clinical settings, include prolongation of contraction and relaxation, compromised relaxation velocity, and impaired contractility ( 3 , 4 ). (diabetesjournals.org)
  • There is convincing experimental and clinical evidence that the generation of ROS is increased in both types of diabetes and that the onset of diabetes and its complications, including diabetic cardiomyopathy, are closely associated with oxidative stress ( 7 , 8 ). (diabetesjournals.org)
  • Professor Danhof has been selected as an outstanding candidate for this award, given his life-long commitment and exceptional achievements in the field of clinical pharmacology. (eacpt.org)
  • He received further specialist training in clinical pharmacology as a visiting scientist at Stanford University Medical Center between 1983-1986. (eacpt.org)
  • In addition to his many research accomplishments and numerous awards, Dr. Danhof has shown genuine leadership in clinical pharmacology. (eacpt.org)
  • His work has formed the very base of Clinical Pharmacology, and has shaped the profession of Clinical Pharmacology. (eacpt.org)
  • With this letter we would like to endorse the nomination of Prof. Dr. Meindert Danhof for the EACPT Prize 2021 for Lifetime Achievement in Clinical Pharmacology. (eacpt.org)
  • Professor Danhof has been selected by the Board of the Dutch Society of Clinical Pharmacology and Biopharmacy as an outstanding candidate for this award, given his life-long commitment and exceptional achievements in the field of clinical pharmacology. (eacpt.org)
  • 2022) Journal of Neuroimmunology , 373, art. (wustl.edu)
  • The international journal of cardiovascular imaging. (regionh.dk)
  • Interestingly, there is growing evidence that CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain early microbiome-host interactions during fetus development Curr Envir Health Rpt (2018) 5:512-521 513 and early infancy are critical factors that will determine life- early onset of type 2 diabetes [33], and, in the latter case, the long health or disease states [9-11]. (sagepub.com)
  • Journal of Diabetes and its Complications, 28 (2). (edu.au)
  • Shortly after his postdoctoral training, he joined the University of Leiden, where he now is Professor Emeritus of Pharmacology in both the Faculty of Science and the Faculty of Medicine. (eacpt.org)
  • In the same experimental system, IL-10 and BDNF gene expressions increased, and in HypoE22 cells, the extract decreased the extracellular dopamine level and increased the DAT gene expression due to the direct interaction of parthenolide with the DAT. (researchgate.net)
  • Results show that both site-specific upregulation (pharmacological or chemogenetic) and chronic downregulation (RNA interference) of MCH communication to the vHP increases impulsive responding in rats, indicating that perturbing this system in either direction elevates impulsivity. (nature.com)
  • Wistar rats) [155], failed to influence food intake during a 1 h ad libitum feeding period, moderate to high doses of CBD (4.4 mg·kg −1 , i.p. [58]. (researchgate.net)
  • International Journal of Experimental Pathology, 96 (3). (edu.au)
  • Dementia: The international journal of social research and practice. (edu.au)
  • Filipović D, Inderhees J, Korda A, Tadić P, Schwaninger M, Inta D, Borgwardt S. Metabolic Fingerprints of Effective Fluoxetine Treatment in the Prefrontal Cortex of Chronically Socially Isolated Rats: Marker Candidates and Predictive Metabolites . (uni-luebeck.de)
  • Methods: Spontaneously hypertensive rats implanted with radiotelemeters were whole-body exposed to either 500 μg/m 3 (high) or 150 μg/m 3 (low) whole DE (wDE) or filtered DE (fDE), or to filtered air (controls), for 4 hr. (nih.gov)
  • A manuscript was submitted detailing a study investigating the effects of doxorubicin in Zucker diabetic fatty rats. (hesiglobal.org)
  • Journal of Cerebral Blood Flow and Metabolism, vol. 28, no. 1, pp. 99-110. (ottawaheart.ca)
  • Network pharmacology is increasingly applied in CM formula research in recent years, which is identified suitable for the study of CM formula. (springer.com)
  • Finally, we proposed prospective in the future and limitations of network pharmacology, expecting to provide new strategy and thinking on study for CM formula. (springer.com)
  • Potential synergistic and multitarget effect of herbal pair Chuanxiong Rhizome-Paeonia Albifora Pall on osteoarthritis disease: a computational pharmacology approach. (springer.com)
  • In this review, we summarized the methodology of network pharmacology, including network construction, network analysis and network verification. (springer.com)
  • Network pharmacology. (springer.com)
  • This award offers Postdoctoral or Early Career researchers working in cardiovascular safety science or a related field, an opportunity to share your research, learn from and network with experts in the toxicology and safety pharmacology fields from academia, regulatory agencies and pharmaceutical companies. (hesiglobal.org)
  • International Journal of Experimental Pathology, 96 (3). (edu.au)
  • Dementia: The international journal of social research and practice. (edu.au)
  • Journal of Heart & Lung Transplantation, vol. 27, no. 9, pp. 1043-1045. (ottawaheart.ca)