• Triple resonance experiments are a set of multi-dimensional nuclear magnetic resonance spectroscopy (NMR) experiments that link three types of atomic nuclei, most typically consisting of 1H, 15N and 13C. (wikipedia.org)
  • These problems may be alleviated by using heteronuclear NMR spectroscopy which allows the proton spectrum to be edited with respect to the 15N and 13C chemical shifts, and also reduces the overlap of resonances by increasing the number of dimensions of the spectrum. (wikipedia.org)
  • The group uses biomolecular NMR spectroscopy coupled to biochemical, biophysical and computational methods to study the structure/function activity of proteins (or protein domains) involved in human diseases (e.g. cancer, genetic diseases). (hsr.it)
  • We recovered 13C-labelled metabolites by microdialysis and utilised nuclear magnetic resonance spectroscopy (NMR) for identification and quantification.Of 33 patients with complete monitoring, 73% had MD at some point during monitoring. (cam.ac.uk)
  • Experimental methods of multi-dimensional NMR spectroscopy, dynamics and theoretical description of spin system evolution, multiple resonance NMR technique for structural studies of proteins and nucleic acids by NMR spectroscopy, contemporary methods of structural biology, studies of complex biomolecular systems. (muni.cz)
  • In 1990, Ad Bax and coworkers developed the triple resonance technology and experiments on proteins isotopically labelled with 15N and 13C, with the result that the spectra are dramatically simplified, greatly facilitating the process of resonance assignment, and increasing the size of the protein that may be determined by NMR. (wikipedia.org)
  • PROTEIN BIOTECHNOLOGY , from design of engineered proteins to the structure of membrane protein targets for ligand discovery and biomolecular medicine. (iit.it)
  • The ISSN of TrAC - Trends in Analytical Chemistry journal is 01659936 . (resurchify.com)
  • Organic & Biomolecular Chemistry, 2010. (bionmr.com)
  • Nuclear Magnetic Resonance (NMR) is an important spectroscopic tool for the identification and structural characterization of molecules in chemistry and biochemistry. (bionmr.com)
  • Dynamic nuclear polarization allows hyperpolarization of most spins in small molecules encountered in chemistry and biochemistry. (bionmr.com)
  • Organic & Biomolecular Chemistry, 9 (3), pp. 881-891. (bath.ac.uk)
  • A (19)F, (13)C- rotational-echo double-resonance NMR strategy was used to determine the structure of an inhibitor in the digitalis receptor site, and it showed that the ouabain derivatives adopt a conformation in which the sugar extends out of the plane of the steroid ring system. (ox.ac.uk)
  • The ISSN of Electron Paramagnetic Resonance book series is 14651955, 14644622 . (resurchify.com)
  • The ISSN of Electron Paramagnetic Resonance is 14651955, 14644622 . (resurchify.com)
  • Triple resonance experiments can also be used in sequence-specific backbone resonance assignment of magic angle spinning NMR spectra in solid-state NMR. (wikipedia.org)
  • A way of increasing sensitivity of single scan NMR spectra by several orders of magnitude is through hyperpolarization of nuclear spins. (bionmr.com)
  • The signals observed in in vivo carbon-13 nuclear magnetic resonance (13C NMR) spectra are from 'mobile' molecules, i.e. those with relatively unrestricted motion. (westminster.ac.uk)
  • Journal of Chemical Education 2022 , 99 (5) , 2121-2128. (acs.org)
  • Electron Paramagnetic Resonance is cited by a total of 19 articles during the last 3 years (Preceding 2022). (resurchify.com)
  • The impact score (IS) 2022 of Electron Paramagnetic Resonance is 1.50 , which is computed in 2023 as per its definition. (resurchify.com)
  • These experiments are often used to assign specific resonance signals to specific atoms in an isotopically-enriched protein. (wikipedia.org)
  • Many of these experiments have since become the standard set of experiments used for sequential assignment of NMR resonances in the determination of protein structure by NMR. (wikipedia.org)
  • These triple resonance experiments utilize the relatively large magnetic couplings between certain pairs of nuclei to establish their connectivity. (wikipedia.org)
  • Triple resonance experiments involving 31P may also be use for nucleic acid studies. (wikipedia.org)
  • Sequential assignment using triple resonance experiments These experiments are typically named by the nuclei (H, N, and C) involved in the experiment. (wikipedia.org)
  • Some of the experiments are used in tandem for the resonance assignment of protein, for example HNCACB may be used together with CBCA(CO)NH as a pair of experiments. (wikipedia.org)
  • Other experiments are also necessary to fully assign the side chain resonances. (wikipedia.org)
  • A large number triple-resonance NMR experiments have been created, and the experiments listed below is not meant to be exhaustive. (wikipedia.org)
  • Nuclear magnetic resonance (NMR) experiments combined with size exclusion and analytical ultracentrifugation measurements confirm these observations and reveal BteA287 to be monomeric in nature with a tendency to oligomerize at concentrations above 200 µM. (nih.gov)
  • Paramagnetic Dopants for Dynamic Nuclear Polarization: Can They be Improved Further? (ismar.org)
  • Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)
  • The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. (mdpi.com)
  • There are now innumerable open-access journals, and while many are of dubious quality, funding agencies around the world are increasingly requiring that the research they support be published in an open-access format (1, 2). (mdpi.com)
  • Dr Garau is author and co-author of more than fifty publications in high-quality journals, including JACS, PNAS, Nature Neuroscience and Structure (Cell), a book chapter (X-ray Structures and Mechanisms of Metallo-Beta-Lactamases), and received several research highlights with international collaborators. (iit.it)
  • This limitation is due to the need to assign NMR signals from the large number of nuclei in the protein - in larger protein, the greater number of nuclei results in overcrowding of resonances, and the increasing size of the protein also broadens the signals, making resonance assignment difficult. (wikipedia.org)
  • Resonance assignment of the RGS domain of human RGS10. (ox.ac.uk)
  • Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions. (muni.cz)
  • The magnetic relaxation dispersion method sensitively detects stable oligomers without being affected by other interactions. (lu.se)
  • It is based on Scopus data and can be a little higher or different compared to the impact factor (IF) produced by Journal Citation Report. (resurchify.com)
  • We have used magnetic relaxation dispersion to study bovine pancreatic trypsin inhibitor (BPTI) self-association as a function of pH, salt type and concentration, and temperature. (lu.se)
  • Editor's Choice articles are based on recommendations by the scientific editors of MDPI journals from around the world. (mdpi.com)
  • SCImago Journal Rank is an indicator, which measures the scientific influence of journals. (resurchify.com)
  • Journal of Hematology and Oncology 2016 Oct 28;9(1):115. (hsr.it)
  • doi: 10.1371/journal.pone.0055650. (nih.gov)
  • Spectral density mapping at multiple magnetic fields suitable for C-13 NMR relaxation studies. (muni.cz)
  • Reactive Bubbly Flows Experimental Investigation of Local Hydrodynamics and Chemical Reactions in Taylor Flows Using Magnetic Resonance Imaging %22&body=%0AI%20found%20an%20article%20you%20might%20be%20interested%20in. (deepdyve.com)
  • Journal of Inorganic Biochemistry. (unl.pt)
  • Detailed characterization of the various streams resulting from EA treatment, including compositional analysis, structural characterization by nuclear magnetic resonance (NMR) spectrometry, elemental analysis, molecular weight analysis, and thermo-gravimetric analysis provides a broad evaluation of the EA-derived lignin product stream structures and properties, assessing their potential for commercial applications. (rsc.org)
  • Many of these experiments have since become the standard set of experiments used for sequential assignment of NMR resonances in the determination of protein structure by NMR. (wikipedia.org)
  • National Centre for Biomolecular Research at the Faculty of Science MU is focused on the study of bio(macro)molecules at the atomic level using experimental and computational methods. (timeshighereducation.com)
  • Despite wide-spread use of Nuclear Magnetic Resonance (NMR) in metabolomics for the analysis of biological samples there is a lack of graphically driven, publicly available software to process large one and two-dimensional NMR data sets for statistical analysis. (biomedcentral.com)
  • Dr. Laity then trained at the Scripps Research Institute in La Jolla, California specializing in biomolecular nuclear magnetic resonance (NMR) applications in structural biology. (nih.gov)
  • Microperoxidase-11: molecular dynamics and Q-band excited resonance Raman of the oxidized, reduced and carbonyl forms. (shengsci.com)
  • Spectroscopic techniques such as Fourier transform infrared (FTIR), Raman, nuclear magnetic resonance (NMR) are widely used to characterize biological systems by monitoring cellular molecules such as lipids, carbohydrates, and proteins. (intechopen.com)
  • The solution structure of the self-complementary DNA hexamer 5' d(C-G-T-A-C-G)2 is refined by restrained molecular dynamics in which 192 interproton distances, determined from pre-steady-state nuclear Overhauser enhancement measurements, are incorporated into the total energy of the system in the form of effective potentials. (nih.gov)
  • Analysis of the relative contributions of the nuclear Overhauser interproton distance restraints and the empirical energy function in the calculation of oligonucleotide structures using restrained molecular dynamics. (nih.gov)
  • 17. Clore, G.M. (2000) Accurate and rapid docking of protein-protein complexes on the basis of intermolecular nuclear Overhauser enhancement data and dipolar couplings by rigid body minimization. (nih.gov)
  • The department also provides teaching and training of bachelor's, master's and doctoral students in study programs focused on bioinformatics, biomolecular chemistry, genomics and proteomics, and life sciences. (timeshighereducation.com)
  • Established by the journal Molecules and named after the 2015 Nobel Laureate Dr. Tu Youyou, the honor recognizes researchers who have made significant contributions the advancement of the natural product and medicinal chemistry field. (nih.gov)
  • Pharmaceutical companies use the software to understand biomolecular recognition and design molecules to interfere with this process. (sbgrid.org)
  • Dr Mobli is a Group Leader at the UQ Centre for Advanced Imaging, where he leads a biomolecular NMR group. (edu.au)
  • Journal of Clinical Endocrinology and Metabolism , 106 (11), E4372-E4388. (helsinki.fi)
  • These triple resonance experiments utilize the relatively large magnetic couplings between certain pairs of nuclei to establish their connectivity. (wikipedia.org)
  • Xplor-NIH is a popular software package for biomolecular structure determination from nuclear magnetic resonance (NMR) and other data sources. (researcher-app.com)
  • For projects with public funding, all data on biomolecular shapes are to be made available to the public in all countries soon after their determination. (nih.gov)
  • Previously I was a Senior Machine Learning Engineer and Data Scientist at BenevolentAI and a member of Arthur Palmer's research group where I developed and applied nuclear magnetic resonance (NMR) spin relaxation experiments to understand how enzyme dynamics are critical to biological function. (michellelynngill.com)
  • During that time, he also directed the high field NMR core facility, reviewed for numerous scientific journals, and served as a standing member of the NIH Molecular Structure Function A study section. (nih.gov)
  • The infrared absorption and 1H nuclear magnetic resonance analyses of chloroform solutions of the terminally-blocked segment corresponding to the 2-9 sequence of emerimicins III and IV, -(Aib)3-L-Val-Gly-L-Leu-(Aib)2-, are consistent with the presence of a 3(10)-helical structure of high thermal stability. (shengsci.com)
  • He is the former head of the Nuclear Magnetic Resonance Group, with a secondary appointment in the NIEHS Immunity, Inflammation, and Disease Laboratory. (nih.gov)
  • Frontiers Journal Series The compilation of articles constituting The Frontiers Journal Series is a multi-tier and interdisciplinary set of open-access, online this e-book, wherever published, as well as the compilation of all other journals, promising a paradigm shift from the current review, selection and dissemination content on this site, is the exclusive property of Frontiers. (pdfhost.io)
  • These experiments are often used to assign specific resonance signals to specific atoms in an isotopically-enriched protein. (wikipedia.org)
  • Journal of Hydraulic Engineering. (illinois.edu)
  • The team was led by Antonios G. Mikos, Ph.D., the Louis Calder Professor of Bioengineering, Chemical and Biomolecular Engineering at Rice University, Houston, TX. (nih.gov)
  • To add to the mix, in 1990 the NCBI and the NLM initiated a journal-scanning program to capture and annotate sequences reported in the literature that had not been submitted to any of the sequence databases. (nih.gov)
  • Sort by: date ▼ ▲ title ▲ ▼ journal ▲ ▼ authors ▲ ▼ I.F. (cnr.it)
  • Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)
  • The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. (mdpi.com)
  • They introduced the software in a 2003 paper in the Journal of the American Chemical Society . (sbgrid.org)
  • In a recent NIH-funded study in the journal Nature , researchers screened a chemical "library" that contained nearly 12,000 existing drug compounds for their potential activity against SARS-CoV-2, the novel coronavirus that causes COVID-19 [1]. (nih.gov)