CampylobacterColiTetracyclineNalidixicSalmonellaInfectionGentamicinOutbreakErythromycinSpeciesInfectionsGenesClinicalIleumDuodenumAntibioticsPenicillinGenomeFaeciumAlleles2000EnterococcusHydrochlorideGastricSusceptibleResistance amongAntibiotic23.3AcutePatientsFrequentHuman2020MutationBroilerIllnessesInhibitionHigh
Campylobacter35
- Of the 54 Campylobacter isolates 34 (63%) were C. jejuni and 20 (37%) were C. coli. (usda.gov)
- Campylobacter jejuni usually is the most common cause of community-acquired inflammatory enteritis. (medscape.com)
- Scanning electron microscope image of Campylobacter jejuni, illustrating its corkscrew appearance and bipolar flagella. (medscape.com)
- Campylobacter jejuni was the most frequent species. (irta.cat)
- Out of the 49 bacterial isolates, 3 (6.1%) were Clostridium difficili , 4 (8.2%) were Shigella flexneri , 5 (10.2%) were Campylobacter jejuni , and different Salmonella spp. (microbiologyjournal.org)
- Eighty percent of isolated Campylobacter jejuni were resistant to Ciprofloxacin and Tetracycline. (microbiologyjournal.org)
- La campilobacteriosis (infección por Campylobacter) es la zoonosis de transmisión alimentaria más comúnmente reportada en la mayoría de los países desarrollados y en vías de desarrollo. (una.py)
- Campylobacter jejuni is a major cause of foodborne illnesses worldwide and is primarily transmitted to humans through contaminated poultry meat. (usda.gov)
- Minimal inhibitory concentrations of enrofloxacin, ciprofloxacin and nalidixic acid for 567 Campylobacter jejuni and 233 Campylobacter coli strains were determined by the agar dilution method. (tubitak.gov.tr)
- The antibiotic sensitivity and the serotype and molecular type (MT) distribution of 41 Campylobacter jejuni strains isolated from individual patients in Tawam Hospital, Al Ain, United Arab Emirates, were investigated. (uaeu.ac.ae)
- We report a rising trend in ofloxacin resistance, re-emergence of erythromycin resistance and indications of co-resistance to both drugs in clinical isolates of Campylobacter spp. (who.int)
- CDC, several states, and the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (USDA-APHIS) investigated a multistate outbreak of multidrug-resistant Campylobacter infections. (cdc.gov)
- Whole genome sequencing (WGS) showed that isolates from people infected with Campylobacter were closely related genetically. (cdc.gov)
- Campylobacter bacteria isolated from clinical samples from people sickened in this outbreak were resistant to commonly recommended, first-line antibiotics. (cdc.gov)
- WGS showed that the Campylobacter isolates from sick people in this outbreak and isolates from pet store puppies were closely related genetically, providing additional evidence that people got sick from contact with pet store puppies. (cdc.gov)
- the Campylobacter species that cause human acute intestinal disease such as Campylobacter jejuni and Campylobacter coli originate from animals. (frontiersin.org)
- Some of these animal hosted Campylobacter species, such as Campylobacter jejuni and Campylobacter coli , can cause acute bacterial gastroenteritis in humans through consumption of contaminated food or water ( Galanis, 2007 ). (frontiersin.org)
- As C. jejuni and C. coli are the main Campylobacter pathogens which cause human acute intestinal disease and they originate from animal sources, Campylobacteriosis has historically been considered to be zoonotic. (frontiersin.org)
- To date, 40 Campylobacter species and subspecies have been isolated from a wide variety of animal or human sources (Figure 1 ). (frontiersin.org)
- Susceptibility tests were carried out for 805 strains (697 Campylobacter jejuni and 108 Campylobacter coli) against nalidixic acid, ciprofloxacin, erythromycin, amoxicillin, amoxicillin plus clavulanic acid, tetracycline, gentamicin, and chloramphenicol using the disk-diffusion method. (e3ligase-signal.com)
- Food-borne antibiotic-resistant Campylobacter poses a serious threat to public health. (figshare.com)
- To understand the prevalence and genetic characteristics of Campylobacter in Chinese local dual-purpose (meat and eggs) chickens, the genomes of 30 Campylobacter isolates, including 13 C. jejuni and 17 C. coli from Jianghan-chickens in central China, were sequenced and tested for antibiotic susceptibility. (figshare.com)
- In June 2011, a cluster of suspected cases of Guillain-Barré syndrome (GBS), which can follow Campylobacter jejuni infection, was identified in San Luis Río Colorado (SLRC), Sonora, Mexico and Yuma County, Arizona, USA. (cambridge.org)
- Stool specimens from infected persons or Campylobacter isolates were submitted to state public health laboratories. (medscape.com)
- Campylobacter jejuni isolates were obtained for 51 persons and 23 puppies. (medscape.com)
- Campylobacter jejuni , and Salmonella spp. (uspharmacist.com)
- As in previous years, the occurrence of resistance to several of the tested antimicrobial agents, including ciprofloxacin, was higher in patients with Salmonella Typhimurium and Campylobacter jejuni infections acquired abroad than in patients with infections acquired in Denmark. (ssi.dk)
- Genomic and Phenotypic Characterisation of Campylobacter jejuni Isolates From a Waterborne Outbreak. (cdc.gov)
- Biomolecule sulphation and novel methylations related to Guillain-Barré syndrome-associated Campylobacter jejuni serotype HS:19. (lbl.gov)
- Only one human isolate could be re-grown by the reference laboratory and was confirmed as a Campylobacter jejuni subspecies jejuni , with sensitivity to ciprofloxacin, nalidixic acid, gentamicin and tetracycline. (who.int)
- Campylobacter jejuni and C. coli are zoonotic bacteria recognised as a major cause of human gastroenteritis and frequent cause of bacterial food-borne illness around the world. (journaltocs.ac.uk)
- However, Campylobacter has become increasingly resistant to fluoroquinolones with high isolation rates among human and animal strains. (journaltocs.ac.uk)
- Sin embargo, Campylobacter a llegado a ser cada vez más resistente a fluoroquinolonas, con altas tasas de aislamiento, tanto en seres humanos como en animales. (journaltocs.ac.uk)
- iii) el aislamiento, la identificación y las pruebas de susceptibilidad antimicrobiana para Campylobacter han sido realizadas mediante diferentes métodos analíticos haciendo necesarias la armonización y estandarización de los métodos diagnósticos y iv) es necesario fortalecer los programas de vigilancia de la resistencia antimicrobiana en Campylobacter y las capacidades diagnósticas, con la asociación entre los servicios de salud y las instituciones académicas. (journaltocs.ac.uk)
- We studied Campylobacter jejuni , one of the most common causes of human diarrhea, and Acinetobacter baumannii , which causes wound infections. (biomedcentral.com)
Coli9
- Two C. coli were resistant to ciprofloxacin, nalidixic acid, and tetracycline while 4 C. coli were susceptible to all antibiotics tested. (usda.gov)
- In total, 18% of C. jejuni and 24% of C. coli strains were resistant to enrofloxacin, and 17.5% of C. jejuni and 22.3% of C. coli strains were resistant to ciprofloxacin. (tubitak.gov.tr)
- They survive as commensal bacteria in their hosts, and some species, such as C. jejuni and C. coli , can cause human diseases. (frontiersin.org)
- The results showed that CC-354 and CC-828 were the dominant clonal complexes of C. jejuni and C. coli, respectively, and a phylogenetic analysis showed that three unclassified multilocus sequence types of C. coli were more closely genetically related to C. jejuni than to other C. coli in this study. (figshare.com)
- The antibiotic resistance rate of C. coli was higher than that of C. jejuni. (figshare.com)
- In 2011, the occurrence of resistance to 3rd generation cephalosporins in both Klebsiella pneumoniae (10%) and Escherichia coli (8%) from blood isolates corresponded to that observed in 2010. (ssi.dk)
- In October 2011, 12 of the 13 departments of clinical microbiology in Denmark screened all E. coli and K. pneumoniae urine and blood isolates for ESBL production, EPI-NEWS 39b/12 . (ssi.dk)
- A total of 71 enteropathogenic Escherichia coli (EPEC) strains isolated from children with diarrhoea in Montevideo, Uruguay, were characterized in this study. (microbiologyresearch.org)
- Sensitive to ciprofloxacin are gram-negative aerobic bacteria - enterobacteria (Echerichia coli, Salmonella spp. (wellmedpharm.uz)
Tetracycline5
- Most (n=48) of the isolates were resistant to only tetracycline. (usda.gov)
- One hundred percent (100%) of the isolated strains were sensitive to erythromycin and tetracycline, on the contrary, 22% of strains resistant to ciprofloxacin were observed. (una.py)
- The ciprofloxacin and tetracycline resistance phenotypes correlated strongly with the GyrA T86I mutation and tet(O)/tet(L), respectively, but for other antibiotics, the correlation between genes and resistance phenotypes were weak, indicating that there may be resistance mechanisms other than the resistance genes detected in this study. (figshare.com)
- Eighteen outbreak isolates (10 human and eight puppy) representing all three clades were selected for antibiotic susceptibility testing, and all were resistant to azithromycin, ciprofloxacin, clindamycin, erythromycin, nalidixic acid, telithromycin, and tetracycline. (medscape.com)
- More than half of the strains (54%) were resistant to penicillin, 29.4% to tetracycline, 23.5% to erythromycin, and 17% showed resistance to ciprofloxacin. (hindawi.com)
Nalidixic2
- However, the resistance of campylobacters to quinolones increased dramatically in 2000, with 75.5%, 73% and 94.5% of the strains being resistant to enrofloxacin, ciprofloxacin and nalidixic acid, respectively. (tubitak.gov.tr)
- A high level of cross-resistance was observed among enrofloxacin, ciprofloxacin and nalidixic acid. (tubitak.gov.tr)
Salmonella1
- However, detecting the emerging of antibiotic-resistant of GIT bacterial pathogens among patients in Oman, such as Salmonella and Shigella to a commonly used antibiotic such as Gentamicin, is alarming. (microbiologyjournal.org)
Infection4
- One paper estimated that direct infection with resistant bacteria from an animal source, or through ingestion of bacteria from contaminated meat or water, was a relatively small risk in comparison with the overall burden of resistant disease. (ucdavis.edu)
- Exposure information and an environmental assessment suggested that GBS cases resulted from a large outbreak of C. jejuni infection from inadequately disinfected tap water in SLRC. (cambridge.org)
- According to the Centers for Disease Control and Prevention (CDC), at least 2.8 million individuals get an antibiotic-resistant infection, and more than 35,000 individuals died as a result [ 3 ]. (hindawi.com)
- For a better understanding of the adapation of this bacterium to the host conditions, we performed a transcriptome analysis of bacteria isolated from an infection site (mouse peritonitis) by RNA-sequencing. (uni-bielefeld.de)
Gentamicin3
- and Shigella flexneri were highly resistant to Amikacin, Gentamicin, and Cefuroxime. (microbiologyjournal.org)
- In addition, 10 were resistant to gentamicin, and 2 were resistant to florfenicol. (cdc.gov)
- In addition, 16 of 18 isolates were resistant to gentamicin, and four of 18 were resistant to florfenicol. (medscape.com)
Outbreak8
- Using WGS, we identified multiple antimicrobial resistance genes and mutations in most isolates from 38 ill people and 10 puppies in this outbreak. (cdc.gov)
- This finding matched results from standard antibiotic susceptibility testing methods used by CDC's National Antimicrobial Resistance Monitoring System laboratory on isolates from five ill people and seven puppies in this outbreak. (cdc.gov)
- This multidrug-resistant outbreak highlights the need for responsible use of antibiotics in pets. (cdc.gov)
- Outbreak isolates from 45 persons and 11 puppies grouped into three distinct clades by wgMLST. (medscape.com)
- Twelve puppy isolates were also unrelated to the outbreak by wgMLST. (medscape.com)
- This paper describes an outbreak of vancomycin-resistant enterococci in a Perth hospitaland was published as part of the Communicable Diseases Intelligence supplement on Antimicrobial resistance in Australia, (Volume 27, Suppl, May 2003). (health.gov.au)
- A large single-strain outbreak of vancomycin-resistant Enterococcus faecium (VREF) vanB occurred in Royal Perth Hospital from July to December 2001. (health.gov.au)
- We conclude that during single-strain outbreaks of vancomycin-resistant enterococci in hospitals, patient contacts need to be screened on more than three occasions in order to detect most of the carriers and control the outbreak. (health.gov.au)
Erythromycin1
- While all strains were sensitive to erythromycin (MIC 0.5-4 mg l -1 ), 35 isolates (85.4%) exhibited resistance to ciprofloxacin (MIC 8-64 mg l -1 ). (uaeu.ac.ae)
Species2
- Discovered in 2009, the species (as strain UMB49T) was isolated from 120,000 years old glacial ice, 3,042 metres (1.9 mi) deep, from Greenland. (wikipedia.org)
- DNA sequence analysis suggests that with a sequence similarity of 99.6%, H. glaciei is most closely related to H. saxobsidens, a species originally isolated from lichen-colonized rock. (wikipedia.org)
Infections6
- [ 3 ] C jejuni infections also may produce serious bacteremic conditions in individuals with AIDS . (medscape.com)
- Some strains of C jejuni produce a heat-labile, cholera-like enterotoxin, which is important in watery diarrhea observed in infections. (medscape.com)
- The treatment of these infections has been hampered by the appearance of resistant strains. (microbiologyjournal.org)
- A British study on antimicrobial resistance (AMR) estimated that 700,000 persons are dying each year worldwide due to antibiotic-resistant infections [ 4 ]. (hindawi.com)
- In 2011, the World Health Organization (WHO) reported that 63,000 patients die each year in US hospitals and 25,000 patients lose their lives annually in the European Union due to antibiotic-resistant infections. (cedevelopment.org)
- Several studies have illustrated the therapeutic efficacy of photoactivated riboflavin against nosocomial infections and multidrug resistant bacterial infections as well as microbial associated biofilm infections, revealing the potential role of riboflavin as a promising antimicrobial candidate, which could serve as one of the alternatives in fighting the global crisis of the emergence of antimicrobial resistance seen in different pathogenic microbes. (bioseek.eu)
Genes5
- Virulence gene analysis showed that several genes related to adhesion, colonization, and invasion (including cadF, porA, ciaB, and jlpA) and cytolethal distending toxin (cdtABC) were only present in C. jejuni. (figshare.com)
- The presence of 16S rRNA, nuc , mec A, mec C, Panton-Valentine leukocidin (PVL), and the toxic shock syndrome toxin 1 (TSST-1) genes were detected by PCR analysis for all isolates. (hindawi.com)
- Zoonotic resistant bacteria and resistance genes could be transferred not only to people with occupational livestock exposure but also other persons in the community through direct contact with animals, via the food chain or by environment [ 9 , 10 ]. (hindawi.com)
- 1). EPEC isolates were examined for the presence of eaeA , bfpA and stx genes by PCR. (microbiologyresearch.org)
- PCR showed that 57 isolates carried eae and bfp genes (typical EPEC strains), and 14 possessed only the eae gene (atypical EPEC strains). (microbiologyresearch.org)
Clinical1
- Clinical isolates of the gastric pathogen Helicobacter pylori display a high level of genetic macro- and microheterogeneity, featuring a panmictic, rather than clonal structure. (biomedcentral.com)
Ileum1
- The sites of tissue injury include the jejunum, the ileum, and can extend to involve the colon and rectum. (medscape.com)
Duodenum1
- When taken orally, it is rapidly and completely absorbed from the gastrointestinal tract (mainly in the duodenum and jejunum). (wellmedpharm.uz)
Antibiotics3
- Antibiotic susceptibility testing for nine antibiotics was performed by broth microdilution (Sensititer, Thermo Fisher Scientific) on selected isolates and interpreted using epidemiologic cutoff values established by the European Committee on Antimicrobial Susceptibility Testing. (medscape.com)
- The enormous use of animals intended for food promotes the selection of new antibiotics resistant bacteria, which will contribute to increasing the risk of zoonotic transmission [ 6 ]. (hindawi.com)
- While taking ciprofloxacin, there is no parallel development of resistance to other antibiotics that do not belong to the group of gyrase inhibitors, which makes it highly effective against bacteria that are resistant, for example, to aminoglycosides, penicillins, cephalosporins, tetracyclines and many other antibiotics. (wellmedpharm.uz)
Penicillin1
- Mice were treated with either ciprofloxacin, penicillin, or water (control) for a 5-day period followed by a 5-day washout period prior to oral challenge with C. jejuni or A. baumannii to assess antibiotic effects on colonization susceptibility. (biomedcentral.com)
Genome1
- Genome analysis of C. concisus strains isolated from saliva samples has identified a bacterial marker that is associated with active Crohn's disease (one major form of IBD). (frontiersin.org)
Faecium1
- In contrast, ampicillin resistance was high (93 %) in Enterococcus faecium isolates from blood, while the occurrence of vancomycin resistance was low (1.3%) for E. faecium isolates. (ssi.dk)
Alleles3
- Based on the partial sequences of gyrA, resistant isolates carried 10 distinct alleles, eight of them representing new variants. (uaeu.ac.ae)
- Two clades contained isolates from persons and puppies that were genetically related (≤32 alleles difference within each clade). (medscape.com)
- The third clade contained six patient isolates that were related (≤30 alleles difference). (medscape.com)
20001
- Fluoroquinolone resistant strains originated from 7.1% of 28 broiler flocks in 1992, and from 92.9% of 14 flocks in 2000. (tubitak.gov.tr)
Enterococcus1
- It can be accessed online at www.helmholtz-hiri.de/en/datasets/enterococcus through an instance of the genomic viewer JBrowse. (frontiersin.org)
Hydrochloride4
- Prices for Ciloxan (Ciprofloxacin hydrochloride) according to the dosage forms and number of pills. (antiinfectivemeds.com)
- Ciprofloxacin hydrochloride is authorised in the world under the following brand names: Ciloxan. (antiinfectivemeds.com)
- Ciprofloxacin hydrochloride does not interfere with urinary glucose determinations using cupric sulfate solution (e.g. (antiinfectivemeds.com)
- Ciprofloxacin (in the form of ciprofloxacin hydrochloride). (wellmedpharm.uz)
Gastric1
- If acute overdosage of ciprofloxacin occurs, the stomach should be emptied by inducing emesis or by gastric lavage. (antiinfectivemeds.com)
Susceptible4
- only 11.7 % of the isolates were pan-susceptible and 17.6 % were multi-resistant. (irta.cat)
- Newport was isolated only from one Pyrenean chamois and was pan-susceptible. (irta.cat)
- Like other fluoroquinolone anti-infectives, ciprofloxacin inhibits DNA synthesis in susceptible organisms via inhibition of the enzymatic activities of 2 members of the DNA topoisomerase class of enzymes, DNA gyrase and topoisomerase IV. (antiinfectivemeds.com)
- However, pan-susceptible populations (total 10.3%) were isolated in our survey. (e3ligase-signal.com)
Resistance among2
- Emergence of Quinolone Resistance among Chicken Isolates of Campylobac" by SERAP SAVAŞAN, ALPER ÇİFTÇİ et al. (tubitak.gov.tr)
- These results show that the local incidence of fluoroquinolone resistance among C. jejuni is one of the highest reported worldwide. (uaeu.ac.ae)
Antibiotic4
- It was also demonstrated that stable MTs could persist for a relatively long time among the clonally unrelated antibiotic-resistant isolates of C. jejuni. (uaeu.ac.ae)
- Industrial food animal production facilities are known to be a source of human exposure to antibiotic-resistant S. aureus including methicillin-resistant S. aureus (MRSA) [ 5 , 6 ]. (hindawi.com)
- The evolution of S. aureus in the antibiotic era has revealed the emergence of virulent strains, many of which include acquisition of antibiotic resistant to methicillin [ 15 , 16 ]. (hindawi.com)
- Despite the significant potential consequences for AMR in livestock, our knowledge about antibiotic-resistant S. aureus carriage among food-producing animals in Tangier is still limited. (hindawi.com)
23.31
Acute2
- Limited information is available on the acute toxicity of ciprofloxacin in humans. (antiinfectivemeds.com)
- A Distinct Phylogenetic Cluster of Indian Severe Acute Respiratory Syndrome Coronavirus 2 Isolates. (cdc.gov)
Patients2
- Twenty-one (81%) patients reported antecedent diarrhoea, and 61% of 18 patients tested were seropositive for C. jejuni IgM antibodies. (cambridge.org)
- Patients carrying VREF were strictly isolated and ward contacts were segregated, cohorted and screened. (health.gov.au)
Frequent1
- a The five most frequent countries of origin of ciprofloxacin-resistant C. jejuni isolates were included in this analysis. (cdc.gov)
Human2
- 3. What is the current state of knowledge about the transfer of resistant bacteria from livestock farms and manure use to human populations? (ucdavis.edu)
- isolates of human and animal origin. (cdc.gov)
20201
- 2020. Evaluation of cellulase activity of fungi isolated from vanilla beans (Vanilla planifolia Jacks. (msstate.edu)
Mutation1
- All resistant strains carried the Thr-86 to He mutation in the gyrase A (gyrA) gene, as shown by mismatch amplification mutation assay (MAMA) and confirmed by sequencing. (uaeu.ac.ae)
Broiler1
- The development and extent of quinolone-resistance in broiler isolates of campylobacters over a 15-year period was investigated. (tubitak.gov.tr)
Illnesses1
- Six persons whose illnesses did not meet the case definition because their isolates were unrelated by wgMLST were excluded. (medscape.com)
Inhibition1
- In-vitro metabolism studies demonstrated significant inhibition of riluzole metabolism when it was co-incubated with ciprofloxacin or grapefruit juice. (researchgate.net)
High1
- A high genetic diversity and certain host specificity of C. jejuni isolates was observed. (irta.cat)