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  • neoplasm
  • Depending on the nature of the myeloproliferative neoplasm, diagnostic tests may include red cell mass determination (for polycythemia), bone marrow aspirate and trephine biopsy, arterial oxygen saturation and carboxyhaemoglobin level, neutrophil alkaline phosphatase level, vitamin B 12 (or B 12 binding capacity), serum urate or direct sequencing of the patient's DNA. (wikipedia.org)
  • Chronic myelomonocytic leukemia (CMML) is a malignant hematopoietic stem cell disorder with clinical and pathological features of both a myeloproliferative neoplasm (MPN) and myelodysplastic syndrome (MDS). (uptodate.com)
  • genes
  • Although CMML does have a distinct 'genetic fingerprint' (ie, a unique frequency and pattern of mutated genes), there is no single disease-defining mutation or chromosomal abnormality. (uptodate.com)