• That 11 of the 13 individuals described by Churg and Strauss in their 1951 paper had died of CSD is not surprising since corticosteroids were only introduced into medical practice in 1951 and did not become readily available for use in medicine until suitable synthetic preparations were prepared. (medscape.com)
  • Churg-Strauss syndrome or disease (CSD), now known as eosinophilic granulomatosis with polyangiitis (EGPA), is a specific variant of the group of diseases characterized by necrotizing vasculitis of small- and medium-sized systemic blood vessels. (medscape.com)
  • The quicksand death of Churg-Strauss was heralded by the 2012 Chapel Hill vasculitis consensus jury who declared that the old (Churg-Strauss) was out and the new (eosinophilic granulomatosis with polyangiitis-EGPA) was in. (rheumnow.com)
  • While many still cling to the familiarity of "Churg-Strauss", EGPA has become the preferred term based on this consensus conference whose naming objectives preferred to focus on the histopathology of the disease. (rheumnow.com)
  • Strauss, alongside Jacob Churg, attributed her name to Churg-Strauss syndrome, which is now known as eosinophilic granulomatosis with polyangiitis. (wikipedia.org)
  • Churg strauss syndrome. (lookformedical.com)
  • Clinicopathological features of Churg-Strauss syndrome-associated neuropathy. (lookformedical.com)
  • We assessed the clinicopathological features of 28 patients with peripheral neuropathy associated with Churg-Strauss syndrome. (lookformedical.com)
  • Necrotizing vasculitis mediated by cytotoxic T cells, leading to ischaemic changes, appears to be a major cause of Churg-Strauss syndrome-associated neuropathy. (lookformedical.com)
  • Several cases of eosinophilic conditions including Churg-Strauss syndrome have been reported to be associated with zafirlukast, a cysteinyl leukotriene type 1 receptor antagonist. (lookformedical.com)
  • We believe that cysteinyl leukotriene type 1 receptor antagonists are safe and effective drugs for most patients with asthma but caution is needed for those with more severe disease who require systemic corticosteroids, especially if they show characteristics of the atypical allergic diathesis seen in the prodromal phase of Churg-Strauss syndrome. (lookformedical.com)
  • La granulomatose éosinophilique avec polyangéite (GEPA) ou syndrome de Churg-Strauss, est une vascularite rare décrite pour la première fois par Jacob Churg et Lotte Strauss en 1951. (bvsalud.org)
  • However, it was not until 1951 that Jacob Churg and Lotte Strauss of Sweden clearly identified the clinical and pathological findings as representative of a distinct entity, setting it apart from PAN. (medscape.com)
  • However, it was not until 1951 that Jacob Churg and Lotte Strauss of Sweden clearly identified the clinical and pathological findings as representative of a distinct entity, setting it apart from PAN. (medscape.com)
  • That 11 of the 13 individuals described by Churg and Strauss in their 1951 paper had died of CSD is not surprising since corticosteroids were only introduced into medical practice in 1951 and did not become readily available for use in medicine until suitable synthetic preparations were prepared. (medscape.com)