SporanoxFungalDose of itraconazoleAmphotericinAbsorptionBrand of itraconazoleTaken with itraconazoleFormulation of itraconazoleAzoleActive ingredientTerbinafineSystemicTriazole antifungal agentEfficacyOnychomycosisDrug InteractionsOrallyFungusTabletsVoriconazoleItrafungolDosesCanditralInhibitorInfectionDoctor or pharmacistYeast infectionsMedicationsCoadministrationClinicalHedgehogTreatmentAzolesDizzinessLiverOralAllergicPatients
Sporanox7
- The Sporanox brand of itraconazole has been developed and marketed by Janssen Pharmaceutica, a subsidiary of Johnson & Johnson. (wikipedia.org)
- Itraconazole capsules (Sporanox, Tolsura) are used to treat fungal infections in the lungs that can spread throughout the body. (medlineplus.gov)
- Itraconazole capsules (Sporanox) are also used to treat fungal infections of the fingernails and toenails. (medlineplus.gov)
- If you are taking itraconazole capsules (Sporanox, Tolsura) to treat fungal infections in the lungs, the capsules are usually taken during or right after a full meal one or two times a day for at least 3 months. (medlineplus.gov)
- If you are taking itraconazole capsules (Sporanox) to treat fungal infections of the toenails (including or without fingernail infections), the capsules are usually taken once a day with a full meal for 12 weeks. (medlineplus.gov)
- If you are taking itraconazole capsules (Sporanox) to treat fungal infections of the fingernails only, the capsules are usually taken twice a day with a full meal for 1 week, skipped for 3 weeks, and then taken twice a day with a meal for a week. (medlineplus.gov)
- Fluconazole (Diflucan - Pfizer) and itraconazole (Sporanox - Janssen) are both claimed to be effective oral therapy for vaginal candidosis. (bmj.com)
Fungal23
- Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. (wikipedia.org)
- However, if you are taking itraconazole to treat a serious fungal infection in the lungs, the capsules may be taken with a meal three times a day for the first 3 days of treatment and then taken once or twice a day with a meal for at least 3 months. (medlineplus.gov)
- To take itraconazole oral solution for fungal infections of the mouth or throat, swish 10 milliliters (about 2 teaspoons) of the solution in your mouth for several seconds and swallow. (medlineplus.gov)
- The mode of action of itraconazole is based on its binding ability to fungal cytochrome p-450 iso-enzymes. (drugs.com)
- Itraconazole (CARITRA 100 CAPSULE) is an antifungal agent, prescribed for treating fungal infections. (medindia.net)
- Itraconazole EDTA Nasal Spray is a prescription nasal antifungal medication used to treat fungal infections in the nose. (canadapharmacy.com)
- Itraconazole is an azole antifungal that works by blocking the synthesis of a chemical that is essential to the fungal cell membrane's ability to establish itself and expand on the tissue of the inner nose and sinuses. (canadapharmacy.com)
- If Itraconazole nasal spray side effects are experienced, you may want to discontinue use and talk to your doctor again regarding allergic fungal sinusitis treatment options. (canadapharmacy.com)
- Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. (ecancer.org)
- Itraconazole (ITZ) is a triazole anti-fungal treatment widely used in the prevention and systemic treatment of a broad range of fungal infections, including aspergillosis , blastomycosis , candidiasis , histoplasmosis , and in some dermatological and nail infections. (ecancer.org)
- Itraconazole is a prescription antifungal medication used to treat certain types of fungal diseases in dogs and cats. (vetrxdirect.com)
- Itraconazole may be prescribed to treat fungal infections of the respiratory system, total systemic infections, or skin infections such as ringworm. (vetrxdirect.com)
- Itraconazole is a drug that treats fungal infections. (vetrxdirect.com)
- Itraconazole is a synthetic triazole antifungal drug approved for treatment and prophylaxis of a variety of fungal infections. (marshfieldlabs.org)
- Canditral (Itraconazole) is an oral anti-fungal medication prescribed to treat patients suffering from a wide variety of fungal infections. (4nrx-uk.md)
- Itraconazole is a synthetic triazole antifungal agent that slows fungal cell growth by inhibiting CYP450-dependent synthesis of ergosterol, a vital component of fungal cell membranes. (medscape.com)
- Introducing Itraconazole Capsules - an advanced solution for fungal infections! (glasierwellness.com)
- Itraconazole is commonly used to treat infections such as dermatophytosis, systemic fungal infections, and vaginal candidiasis. (glasierwellness.com)
- A higher dose of itraconazole is usually prescribed for more severe or resistant fungal infections, such as onychomycosis. (glasierwellness.com)
- Itraconazole Capsule is highly effective in treating dermatophytosis, which is a fungal infection that affects the skin, nails, and hair. (glasierwellness.com)
- Itraconazole Capsule is highly effective in treating vaginal candidiasis, which is a common fungal infection that affects the vagina. (glasierwellness.com)
- Itraconazole Capsule is effective in treating fungal infections caused by various types of fungi, including Aspergillus, Candida, and Histoplasma. (glasierwellness.com)
- Treatment consisted of surgery and adjunctive anti-fungal therapy with itraconazole. (bvsalud.org)
Dose of itraconazole1
- On Day 8, a single dose of AZD3293 will be coadministered as an oral solution after the morning dose of itraconazole. (astrazenecaclinicaltrials.com)
Amphotericin3
- We evaluated the in vitro activity of voriconazole, amphotericin B, and itraconazole against 192 clinical mould isolates recovered in twenty Italian microbiology laboratories. (unimi.it)
- Voriconazole's activity against the 192 mould isolates was comparable to that of amphotericin B and itraconazole: voriconazole MIC90 (CLSI 1 µg/ml, Sensititre 1 µg/ml), itraconazole MIC90 (CLSI 0.5 µg/ml, Sensititre 0.5 µg/ml), amphotericin B MIC90 (CLSI 1 µg/ml, Sensititre 1 µg/ml). (unimi.it)
- In vitro activity (MIC and MFC) of voriconazole, amphotericin B, and itraconazole against 192 filamentous fungi : the GISIA-2 study / G. Morace, M. Drago, M.M. Scaltrito, S. Conti, F. Fanti, L. Polonelli, T. GISIA Participants Group. (unimi.it)
Absorption5
- Itraconazole may be taken with orange juice or cola, as absorption is also improved by acid. (wikipedia.org)
- Absorption of itraconazole is impaired when taken with an antacid, H2 blocker or proton pump inhibitor. (wikipedia.org)
- Itraconazole capsules should be given with high-fat foods such as cheese, cream, or butter to increase their absorption. (vetrxdirect.com)
- Verifying systemic absorption of orally administered itraconazole. (marshfieldlabs.org)
- The supra-bioavailable formulation of itraconazole in an Itraconazole Capsule ensures maximum absorption and bioavailability. (glasierwellness.com)
Brand of itraconazole1
- The Tolsura brand of itraconazole isn't so much for use in treating parasitic contaminations of the fingernails or toenails. (reliablechemist.com)
Taken with itraconazole1
- Some medications should not be taken with itraconazole. (medlineplus.gov)
Formulation of itraconazole1
- Recently, a feline-approved liquid formulation of itraconazole has entered the market, opening an on-label, more convenient route to treat ringworm. (vin.com)
Azole1
- citation needed] Itraconazole is a relatively well-tolerated drug (although not as well tolerated as fluconazole or voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals: elevated alanine aminotransferase levels are found in 4% of people taking itraconazole "small but real risk" of developing congestive heart failure liver failure, sometimes fatal The cyclodextrin used to make the syrup preparation can cause diarrhea. (wikipedia.org)
Active ingredient2
- The active ingredient in EDTA nasal spray is Itraconazole. (canadapharmacy.com)
- GLASITRA SB 130 CAPSULE also contains ITRACONAZOLE as the active ingredient but in a higher dose of 130 mg. (glasierwellness.com)
Terbinafine1
- Oral therapies include terbinafine, itraconazole, or others. (vin.com)
Systemic3
- The pathogenesis is most likely an itraconazole caused increase in systemic budesonide concentration through a reduced/inhibited metabolism leading to inhibition of adrenocorticotrophic hormone secretion along with a direct inhibition of steroidogenesis. (ersjournals.com)
- Itraconazole therapeutic efficacy is greatest when serum concentrations exceed 0.5 mcg/mL for localized infections, or 1.0 mcg/mL for systemic infections. (marshfieldlabs.org)
- Itraconazole is an effective oral systemic antifungal, but is rarely used in pediatrics. (medscape.com)
Triazole antifungal agent1
- Treatment with itraconazole, an orally administered triazole antifungal agent, has recently been recommended for the treatment of ABPA as an efficient alternative or steroid-sparing therapy without serious side-effects 8 - 10 . (ersjournals.com)
Efficacy3
- The purpose of this study was to determine the efficacy of oral liquid itraconazole as a sole agent in the treatment of Microsporum canis in cats. (vin.com)
- The aim of this study was to evaluate the efficacy of itraconazole in the treatment of severe SD. (e-ijd.org)
- With a focus on quality and efficacy, Itraconazole Capsules are designed to deliver optimal results in a safe and reliable manner. (glasierwellness.com)
Onychomycosis1
- Itraconazole is indicated for treating onychomycosis of the toenail caused by the fungus named Trichophyton rubrum or T. mentagrophytes. (medindia.net)
Drug Interactions1
- There is the possibility of negative drug interactions between itraconazole EDTA nasal spray and other Rx or OTC medications, including avanafil / cisapride / eliglustat / irinotecan / isavuconazonium / methadone / naloxegol / ranolazine / ticagrelor / lurasidone / pimozide / lomitapide / lovastatin / simvastatin / dihydroergotamine / ergonovine / ergotamine / methylergonovine / eplerenone / felodipine / ivabradine / nisoldipine / disopyramide / dofetilide / dronedarone / triazolam. (canadapharmacy.com)
Orally2
- In Group 1, itraconazole will be administered orally twice daily starting on Day 5 for 9 consecutive days (Days 5 to 13). (astrazenecaclinicaltrials.com)
- Itraconazole Capsule is easy to use and can be taken orally, which makes it convenient for patients. (glasierwellness.com)
Fungus4
- If you are taking itraconazole to treat a nail infection, your fungus may not be completely cured until several months after you finish taking itraconazole. (medlineplus.gov)
- How long does itraconazole take to treat a fungus? (rizochem.com)
- Generic Itraconazole (Itrotab) Itraconazole is an antifungal medication that's used in adults to treat infections caused by fungus. (reliablechemist.com)
- Itraconazole stops the growth of fungus by preventing them from making their protective covering. (actizapharmaceutical.com)
Tablets1
- We are leading Exporter and Manufacturer of Itraconazole Tablets. (actizapharmaceutical.com)
Voriconazole1
- Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). (wikipedia.org)
Itrafungol3
- This page contains information on Itrafungol (Itraconazole) Oral Solution for veterinary use . (drugs.com)
- Each mL of ITRAFUNGOL Oral Solution contains 10 mg itraconazole (Ph. (drugs.com)
- ITRAFUNGOL Oral Solution contains itraconazole, a synthetic broad spectrum triazole antimycotic with activity against dermatophytes ( Trichophyton spp. (drugs.com)
Doses4
- Itraconazole caused malformations and foetal resorptions when administered at high doses to rats and mice. (drugs.com)
- Itraconazole is, like other antibiotics, administered in high doses in CF patients due to the endobronchial barrier and altered pharmocokinetics, especially with regard to the increased renal excretion 11 . (ersjournals.com)
- There is evidence that at the clinically relevant doses, itraconazole has potent anti-angiogenic activity, and that it can inhibit the Hedgehog signalling pathway and may also induce autophagic growth arrest. (ecancer.org)
- AIDS patients and organ transplant patients receiving immunosuppressive therapy tend to have lower serum itraconazole levels on standard doses and are thus at high risk of therapeutic failure. (marshfieldlabs.org)
Canditral7
- What is Canditral (Itraconazole) used for? (4nrx-uk.md)
- How should I use Canditral (Itraconazole)? (4nrx-uk.md)
- Always follow your doctor`s instructions while using Canditral (Itraconazole) to get the safest and most effective results from treatment. (4nrx-uk.md)
- What are the side effects of Canditral (Itraconazole)? (4nrx-uk.md)
- Canditral (Itraconazole) should not be administered to patients who are pregnant, breastfeeding, fructose intolerant, or who have porphyrias. (4nrx-uk.md)
- Strictly use Canditral (Itraconazole) as prescribed and follow all instructions provided by your doctor. (4nrx-uk.md)
- Canditral (Itraconazole) may not be safe or suitable for all patients. (4nrx-uk.md)
Inhibitor1
- Itraconazole is a cytochrome p-450 inhibitor and may therefore increase or prolong plasma concentrations of other drugs metabolized by this pathway. (drugs.com)
Infection1
- Itraconazole will dissolve the biofilm coating of the infection, and then a sinus rinse product may be suggested to flush out colonized fungi and mycotoxins. (canadapharmacy.com)
Doctor or pharmacist1
- Before starting, stopping, or changing any medications while taking itraconazole, please get the advice of your doctor or pharmacist. (medlineplus.gov)
Yeast infections1
- Itraconazole oral solution (liquid) is used to treat yeast infections of the mouth and throat or of the esophagus (tube that connects the throat to the stomach). (medlineplus.gov)
Medications3
- Make sure you have discussed any medications you are currently taking or plan to take before starting itraconazole with your doctor and pharmacist. (medlineplus.gov)
- Tell your doctor of all medications you are currently taking before receiving a prescription and proceeding to buy itraconazole nasal spray online. (canadapharmacy.com)
- The treatment group received 5mg/kg itraconazole every 24 hours by mouth for 7 days, then spent a week with no medications. (vin.com)
Coadministration2
- This study is a single-center, open-label, 3-group, fixed-sequence drug-drug interaction study to assess the effect of coadministration of multiple-dose itraconazole or diltiazem on the single-dose PK of AZD3293 and the effects of coadministration of single- and multiple-dose AZD3293 on the single-dose PK of midazolam. (astrazenecaclinicaltrials.com)
- Hepatic enzyme inducers can cause low serum itraconazole levels, and coadministration of these drugs has been associated with itraconazole therapeutic failure. (marshfieldlabs.org)
Clinical4
- After a 5X overdose of itraconazole administered for 6 consecutive weeks to adult cats, reversible clinical side effects were: rough hair coat, decreased food intake and reduced body weight. (drugs.com)
- Clinical trials have shown that patients with prostate, lung, and basal cell carcinoma have benefited from treatment with itraconazole, and there are additional reports of activity in leukaemia, ovarian, breast, and pancreatic cancers. (ecancer.org)
- Given the evidence presented, a case is made that itraconazole warrants further clinical investigation as an anti- cancer agent. (ecancer.org)
- Cats treated with itraconazole experienced a statistically higher rate of mycological and clinical cure, and cures occurred more quickly than in the untreated group. (vin.com)
Hedgehog1
- Recent research works suggest itraconazole (ITZ) could also be used in the treatment of cancer by inhibiting the hedgehog pathway in a similar way to sonidegib. (wikipedia.org)
Treatment5
- Only one patient with an initial pathological ACTH-test subsequently normalised, the other 10 patients improved but had not achieved normalised adrenal function 2-10 months after itraconazole treatment had been discontinued. (ersjournals.com)
- This paper demonstrated that oral, pulsed therapy with itraconazole is an effective method for treatment of ringworm infections in cats, though it will not achieve a cure in all animals. (vin.com)
- Treatment with itraconazole has the best effect on ringworm-causing yeasts one to four weeks after administration. (rizochem.com)
- Each pack of Itraconazole Capsules comes with 10 strips, each containing 10 capsules, making it easy to manage your treatment regimen. (glasierwellness.com)
- For mild to moderate disease that does not involve the central nervous system and does not require hospitalization, itraconazole is the recommended treatment. (msdmanuals.com)
Azoles1
- Azoles such as ketoconazole and itraconazole are strong inhibichrome P450-dependent enzymes such as 17,20 desmolase, 16α-hydroxylase, 17α-hydroxylase, 18 hydroxylase and 11β-hydroxylase enzymes (listed with decreasing activity), thus potentially compromising steroidogenesis in the adrenals and gonads 18 , 19 . (ersjournals.com)
Dizziness1
- Itraconazole may cause dizziness. (medindia.net)
Liver4
- Tell your doctor if you have any history of liver or kidney disease, heart problems, cystic fibrosis, or a weakened immune system before starting on Itraconazole nasal spray. (canadapharmacy.com)
- Liver toxicity is a possible serious side effect of Itraconazole. (vetrxdirect.com)
- There have been a few cases of Itraconazole-induced liver damage that have been extremely serious and potentially lethal. (rizochem.com)
- Itraconazole has infrequently caused veritably serious (conceivably fatal) liver disease. (reliablechemist.com)
Oral4
- Itraconazole oral solution should be taken an hour before food, or two hours after food (and likewise if a combination of capsules and oral solution are used). (wikipedia.org)
- Itraconazole oral solution is usually taken on an empty stomach once or twice a day for 1 to 4 weeks or sometimes longer. (medlineplus.gov)
- Itraconazole capsules and oral solution are absorbed into the body in different ways and work to treat different conditions. (medlineplus.gov)
- The anti-inflammatory activity of oral itraconazole suggests that it should be the first-line therapy in severe SD. (e-ijd.org)
Allergic1
- A recent case of iatrogenic Cushing's syndrome and complete suppression of the pituitary-adrenal-axis in a patient with cystic fibrosis (CF) and allergic bronchopulmonary aspergillosis treated with itraconazole as an antifungal agent, and budesonide as an anti-inflammatory agent led to a systematic assessment of this axis and gonadal function in all patients treated with itraconazole in the authors' CF centre. (ersjournals.com)
Patients13
- citation needed] In the past decade, itraconazole has been explored as an anticancer agent for patients with basal cell carcinoma, non-small cell lung cancer, and prostate cancer. (wikipedia.org)
- Patients with heart failure, leg swelling, hearing loss, neuropathy and lung edema should be extremely cautious while taking Itraconazole. (medindia.net)
- The aim of this study was to evaluate adrenal and gonadal function in patients treated with itraconazole with or without budesonide. (ersjournals.com)
- An adrenocorticotrophic hormone (ACTH) test (250 µg tetracosactid) was performed in 25 CF patients treated with both itraconazole and budesonide, and in 12 patients treated with itraconazole alone (six patients with CF and six with chronic granulomateous disease). (ersjournals.com)
- Eleven of the 25 patients treated with both itraconazole and budesonide had adrenal insufficiency. (ersjournals.com)
- None of the patients on itraconazole therapy alone nor the control CF patients had a pathological ACTH test. (ersjournals.com)
- Suppression of the adrenal glucocorticoid synthesis was observed in 11 of 25 cystic fibrosis patients treated with both itraconazole and budesonide. (ersjournals.com)
- The frequency of suppression of the pituitary-adrenal-axis and gonadal steroidogenesis due to pharmacological interaction of itraconazole and budesonide was prospectively studied in a group of 31 patients with CF and six patients with chronic granulomateous disease (CGD) and compared to a control group of 30 CF patients who had been tested as part of a pretransplantation programme. (ersjournals.com)
- Itraconazole was given to 30 patients of SD in a dose of 100 mg twice daily for 1 week followed by 200 mg/day for first 2 days of the following 2 months. (e-ijd.org)
- Itraconazole Capsule has a high safety profile and is well-tolerated by patients. (glasierwellness.com)
- This phase 0 trial studies how well itraconazole gel works in treating patients with basal cell cancer. (stanfordhealthcare.org)
- Itraconazole gel may help to treat basal cell tumors in patients. (stanfordhealthcare.org)
- Des analyses régulières de la résistance aux antifongiques dans les centres médicaux sont fortement recommandées, car les résultats permettront une prise en charge plus efficace de la candidose systémique chez les patients immunodéprimés. (who.int)