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  • embryos
  • Supporters also emphasized the ethical requirements outlined, noting that all of the embryos destroyed for research under the bill would have been already designated for destruction. (seedmagazine.com)
  • It may also be used to study erythroid progenitors directly in the tissues of genetically modified adult mice or embryos, in order to assess the specific role of the modified molecular pathway in erythropoiesis. (jove.com)
  • Scientists have also derived multipotent stem cells from fetal tissue (taken from embryos older than eight weeks, usually following abortion or spontaneous miscarriage). (wired.com)
  • ECs were first thought to arise from extraembryonic tissues because blood vessels were observed in the avian and mammalian embryos. (wikipedia.org)
  • neural tissue
  • Preclinical and open-label studies have suggested that grafted fetal neural tissue or viral vector gene transfer can achieve considerable biochemical and clinical improvements, whereas subsequent double-blind, placebo-controlled protocols have produced rather more modest and variable results. (hindawi.com)
  • Since the seventies, numerous investigations have focused on trying to restore lost function by replacement of injured brain structures with homologous allogeneic embryonic neural tissue. (utah.edu)
  • liver
  • In this system, mouse fetal liver TER119 (mature erythroid cell marker) negative erythroblasts were purified and transduced with exogenous expression of cDNAs or small hairpin RNAs (shRNAs) for the genes of interest. (jove.com)
  • Fetal liver kinase-1 (Flk-1) is a cell surface receptor protein that is commonly used as a marker for ESCs and EPCs. (wikipedia.org)
  • viral
  • OV research was recently revived by a better knowledge of viral/cancer biology and advances in the methodologies to delete virulence/immune-escape related genes from even complex viral genomes or "to arm" OVs with appropriate transgenes. (springer.com)
  • dopamine
  • Autoradiographic studies indicate that dopamine D 1 and D 2 , muscarinic, cholinergic, 5- HT 2 , opiate μ , β adrenergic and cholecystokinin (CCK) receptors are present in striatal transplants. (hindawi.com)
  • Using positron emission tomography to image the brain, Olle Lindvall of Lund University and a team of colleagues in Lund and at Hammersmith Hospital in London reported in the December issue of Nature Neuroscience that, in one patient, the transplanted neurons are still alive and making dopamine 10 years after the surgery. (bio.net)
  • neurites
  • In all three transplant groups, tracing the TH-positive neurites was easy because they were thicker and coarser than other elements. (hindawi.com)
  • fetuses
  • Aside from ethical concerns about scavenging neurons from aborted fetuses, there are practical issues. (bio.net)
  • Bioethics
  • Bioethics of Fetal Tissue Research The House Energy and Commerce Committee's Select Investigative Panel on Infant Lives held a hearing on the bioethical issues surrounding fetal tissue transplant research. (c-span.org)
  • Faculty collaborate with students in a combination of two retreats and weekly seminars to offer an intellectually rich year introducing the foundations of bioethics as a field, key principles in moral theory, methods of legal and literary analysis, and the skills necessary to apply the insights of bioethics in our daily practice and research. (yu.edu)
  • We examine core bioethics issues using a multiplicity of perspectives and draw upon the depth of expertise not only of faculty but also of our participants, many of whom bring years of clinical, legal and other professional experience to the program. (yu.edu)
  • precursors
  • Here we present a flow-cytometric method of identifying and studying differentiation-stage-specific erythroid progenitors and precursors, directly in the context of freshly isolated mouse tissue. (jove.com)
  • bioreactor
  • Collaborating with Ma on his perfusion bioreactor research were post-doctoral student Feng Zhao and former graduate student Warren Grayson. (scienceblog.com)
  • development
  • Well-controlled trophoblast invasion at maternal-fetal interface is a critical event for the normal development of placenta. (jove.com)
  • The ligand-receptor interaction is essential for normal development of lymphatic tissues. (wikipedia.org)
  • Researchers
  • Brazilian researchers report a relatively large diversity of fungi in marine ecosystems surrounding Antarctica, but warn that climate change could bring unpleasant surprises. (the-scientist.com)
  • 2016
  • Launched in early 2016 to confront the stigma surrounding HIV infection, Prevention Access Campaign's Undetectable = Untransmissible (U=U) movement has received support from major medical organizations including the Centers for Disease Control and Prevention (CDC). (the-scientist.com)
  • clinical
  • This review will focus on the open issues, on the most promising lines of research in the OV field and, more in general, on how OVs could be improved to achieve real clinical breakthroughs in cancers that are usually difficult to treat by immunotherapy. (springer.com)
  • characteristics
  • As the characteristics of the infused tissue can affect convective delivery, this study was performed to determine the effects of the gray and white matter on CED of adenoviruses and similar sized super paramagnetic iron oxide nanoparticles (SPIO). (jove.com)
  • brain
  • However, neurotrammitter receptors may play an important role when functional recovery requires neur0anatomical integration between the host brain and the transplanted tissue. (hindawi.com)
  • The agarose gel model of the brain provides an accessible tool for CED testing, research, and training. (jove.com)
  • Putting fetal brain tissue grafts in the mature central nervous system (CNS) differs from peripheral nerve (PN) grafting in at least the following two ways. (utah.edu)
  • Firstly, while a PN graft is used to bridge two brain areas, an intracerebral embryonic tissue graft is meant to restore the function of the damaged area. (utah.edu)
  • The fetal grafted tissue must develop its own set of connections with the right structures in the host brain, and these connections must be orderly arranged. (utah.edu)
  • For a short period post-implantation, grafted tissue behaves as an immature piece of brain. (utah.edu)
  • Unfortunately, there is abundant literature suggesting that environmental constraints from the mature host brain alter the restorative capacities of fetal grafts in various ways. (utah.edu)
  • role
  • Numerous studies have examined receptor expression in neural transplants and their possible role in transplant-induced functional recovery from lesion-induced deficits. (hindawi.com)
  • The class will consider the role and changing nature of medical views of these issues as well as constitutional and statutory matters. (yu.edu)
  • This method is useful for investigating the role of genes after specific germ layer tissue is derived. (jove.com)
  • medical research
  • They also underlie a host of other federal regulations and guidelines for medical research, and they have worked their way into the private sector as well. (consciencelaws.org)
  • This course will begin with a history of medical research, including research into biological warfare by the US, Germany and Japan during the Second World War. (yu.edu)