• Isoxsuprine belongs to the group of medicines called vasodilators. (mayoclinic.org)
  • Isoxsuprine is available only with your doctor's prescription. (mayoclinic.org)
  • Summary: To examine the effect of beta adrenergic drugs on fetal lung development, we administered isoxsuprine to pregnant rabbits for 24 hr and measured indices of pulmonary surfactant synthesis, storage, and release in rabbit fetuses at 26 days gestation. (semanticscholar.org)
  • There was a significant increase in the rate of choline incorporation into disaturated phosphatidylcholine in the isoxsuprine-treated group and a tendency toward an increased incorporation into total phosphatidylcholine as well. (semanticscholar.org)
  • We also observed an increase in the pulmonary phospholipid reservoir as evidenced by a significant increase in total lung disaturated phosphatidylcholine and a trend toward higher total lung phosphatidylcholine in the isoxsuprine group. (semanticscholar.org)
  • We conclude that isoxsuprine increases synthesis, storage, and release of surfactant in rabbit fetuses at 26 days gestation.Speculation: The effect of isoxsuprine to increase lung disaturated phosphatidylcholine synthesis which leads to an increase in total lung disaturated phosphatidylcholine is probably mediated through an increase in intracellular cyclic adenosine monophosphate. (semanticscholar.org)
  • Neither methazolamide nor isoxsuprine induced significant mean changes in density dependence is of expiratory airflow. (emilybealephotography.com)
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  • Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. (wikipedia.org)
  • Duvadilan Retards contains active ingredient Isoxsuprine Hcl. (premiumrxdrugs.com)
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  • Isoxsuprine Injection 5 mg / ml is used in treatment of Circulatory disturbances and Uterine hypermotility .Each solution for injection (IM or IV) contains isoxsuprine hydrochloride 10mg/2ml. (3scorporation.com)
  • tell your doctor and pharmacist if you are allergic to isoxsuprine, any other medications, or any of the ingredients in isoxsuprine tablets. (medlineplus.gov)
  • Isoxsuprine Hydrochloride Tablets may be used to improve circulation in horses and other species of animals. (valleyvet.com)
  • Isoxsuprine Hydrochloride Tablets cause dilation of blood vessels to improve blood flow and circulation. (valleyvet.com)
  • Isoxsuprine Hydrochloride Tablets may be used in horses to improve circulation to the hooves as an aid in the treatment of navicular disease. (valleyvet.com)
  • Isoxsuprine is used in humans for treatment of premature labor, i.e. a tocolytic, and as a vasodilator for the treatment of cerebral vascular insufficiency, Raynaud's phenomenon, and other conditions. (wikipedia.org)
  • Isoxsuprine is most commonly used to treat hoof-related problems in the horse, most commonly for laminitis and navicular disease, as its effects as a vasodilator are thought to increase circulation within the hoof to help counteract the problems associated with these conditions. (wikipedia.org)
  • Isoxsuprine is a vasodilator and should not be used in mares immediately after foaling or horses that are actively bleeding. (thehorse.com)
  • Isoxsuprine is a vasodilator which helps in increasing the blood flow in the blood vessels. (practo.com)
  • Vasodilator drugs were evaluated at rest (nylidrin, isoxsuprine, and tolazoline) and during exercise (nylidrin, isoxsuprine, and nicotinyl alcohol) in patients with intermittent claudication caused by aortoiliac or femoropopliteal arteriosclerosis obliterans. (annals.org)
  • Typical agents are Isoxsuprine Hcl, ritodrine, terbutaline and salbutamol. (dewcareconcept.com)
  • Uses/Indications - Isoxsuprine is used in veterinary medicine principally for the treatment of navicular disease in horses. (elephantcare.org)
  • Isoxsuprine is most frequently used in horses for the management of navicular disease and laminitis although it is not a universally accepted treatment. (thehorse.com)
  • This is partly because there has been conflicting research on the effects of isoxsuprine and partly because the underlying causes of navicular disease and laminitis are not completely understood. (thehorse.com)
  • In horses with navicular disease, it has been demonstrated that isoxsuprine will raise distal limb temperatures significantly. (elephantcare.org)
  • Take isoxsuprine exactly as directed. (medlineplus.gov)
  • Older adults should not usually take isoxsuprine because it is not as safe and effective as other medications that can be used to treat the same condition. (medlineplus.gov)
  • How should I take isoxsuprine? (rexhealth.com)
  • It is important to take isoxsuprine regularly to get the most benefit. (rexhealth.com)
  • Take Isoxsuprine as advised by the doctor. (practo.com)
  • Isoxsuprine is a β2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β2 receptors. (wikipedia.org)
  • Isoxsuprine will also relax uterine smooth muscle and may have positive inotropic and chronotropic effects on the heart. (elephantcare.org)
  • At high doses, isoxsuprine can decrease blood viscosity and reduce platelet aggregation. (elephantcare.org)
  • In higher doses, isoxsuprine has a relaxant action on the smooth muscles of the uterus. (3scorporation.com)
  • Isoxsuprine is given orally, and many horses find the pills quite palatable. (wikipedia.org)
  • Aginine butyrate, given intravenously, is thought to accelerate wound healing, L-carnitine, given orally, is thought to improve tissue hypoxia , and isoxsuprine, given orally as isoxsuprine hydrochloride, is thought to widen blood vessels, so increasing blood flow to an affected wound. (cochrane.org)
  • Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. (rexhealth.com)
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  • If you become pregnant while taking isoxsuprine, call your doctor. (medlineplus.gov)
  • There are no safety studies on isoxsuprine use in pregnant or lactating mares. (thehorse.com)
  • Pony breeds do not appear to differ from horses in their response to isoxsuprine. (thehorse.com)
  • No information was found on isoxsuprine use in older horses. (thehorse.com)
  • Pharmacokinetics - In humans, isoxsuprine is almost completely absorbed from the GI tract, but in one study that looked at the cardiovascular and pharmacokinetic effects of isoxsuprine in horses (Mathews and et 1986), bioavailability was low after oral administra-tion, probably due to a high first-pass effect. (elephantcare.org)
  • In humans isoxsuprine is sometimes used in the treatment and management of premature labor. (thehorse.com)
  • Isoxsuprine is a beta adrenoceptor agonist with selectivity of action for the smooth muscles of the blood vessels, particularly the cerebral vessels and the deeper vessels of the limbs. (3scorporation.com)
  • It is important to keep accurate records of isoxsuprine and any other medications used if an animal is referred to an equine hospital for intensive care or surgery. (thehorse.com)
  • None of these medications, other than isoxsuprine combined with acetaminophen and caffeine, were reported to have any beneficial effect. (cochrane.org)
  • Isoxsuprine is available only with your doctor's prescription. (mayoclinic.org)
  • The question spent tremely generic isoxsuprine non-prescription at the combination, and was ap much in fine judgment. (thetoxicavengermusical.com)
  • Isoxsuprine belongs to the group of medicines called vasodilators. (mayoclinic.org)
  • Background:The purpose of the study was to compare the efficacy of Isoxsuprine and Nifedipine as tocolytic agent on preterm labour and to compare the Obstetrical outcome following Isoxsuprine and Nifedipine therapy as a tycolytic agent. (who.int)
  • Apgar score of babies less than 7 was 33.3% in Group-A and 32.6% in Group-B. The incidence of perinatal death (16%) in group-A is lower as compared to (19.6%) group-B. Conclusion: Nifedipine is more effective tocolytic agent, as compared to Isoxsuprine. (who.int)
  • Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. (rexhealth.com)
  • Medicine: isoxsuprine Prodigious Pregnancy The pathogenic timing is commonly unknown and is difficult to find out. (sergiolombardi.com)
  • And Nifedipine prolonged pregnancy for 15.427±12.875 days while Isoxsuprine prolonged pregnancy for 13.356±13.612 days. (who.int)
  • Isoxsuprine may also be used for purposes other than those listed in this medication guide. (rexhealth.com)
  • All rats received medication managed daily for 20 days saline solution (SA), nicotine solution (NI), isoxsuprine solution (IS) and nicotine solution (NI) + isoxsuprine solution (IS). (bvsalud.org)
  • it is use in cerebrovascular insufficiency and blood pressure Industry.Isoxsuprine Hydrochloride (579-56-6) is solid. (triveniinterchem.com)
  • Dear sir, please advice me the oral dose rate of isoxsuprine for equine laminitis and also how long i have to administer this medicine?Is it advisable to give omeprazole / ranitidine etc inorder to avoid stomach irritation in horse? (medschat.com)
  • Contraindications/Precautions - Isoxsuprine should not be administered to animals immediately post-partum or in the presence of arterial bleeding. (elephantcare.org)
  • Isoxsuprine is used to relieve the symptoms of central and peripheral vascular diseases such as arteriosclerosis, Buerger's disease, and Raynaud's disease. (medlineplus.gov)
  • Isoxsuprine is used in conditions like Buerger's disease and Raynaud's disease to improve the blood flow in the blood vessels. (practo.com)
  • Isoxsuprine is also used occasionally to treat menstrual pain or prevent premature labor. (medlineplus.gov)
  • A slight increase in the rate of the fetal heart-beat has been noted when isoxsuprine has been given by intravenous infusion in premature labor. (3scorporation.com)
  • Overdose of isoxsuprine increases the risk and severity of the aforementioned side effects. (thehorse.com)
  • Isoxsuprine may cause side effects. (medlineplus.gov)
  • Your doctor may want you to have blood tests or other medical evaluations during treatment with isoxsuprine to monitor progress and side effects. (rexhealth.com)
  • What are the possible side effects of isoxsuprine? (rexhealth.com)
  • The small research included adults of crystalline cow, the probability of which were however suffering from any scotch fingers, but healthy were little with some of the variations of the kind, ever shown by the symptoms of atropin of generic isoxsuprine pricing upon other hands of the gas, and the stiffened fund of the cases. (thetoxicavengermusical.com)
  • Microscopic examination revealed no significant findings in the study of TRAM under the action of isoxsuprine and nicotine to the percentage of necrosis in the left and right cranial and caudal regions. (bvsalud.org)
  • group-A consisted of 48 patients, treated with Nifedipine for tocolysis, the group-B consisted of 52 patients, who received isoxsuprine for tocolysis, and were monitored throughout the course of treatment. (who.int)
  • Result:Successful tocolysis was achieved by Nifedipine in 77.1% of the case as compared to 67% with the isoxsuprine treated cases. (who.int)
  • The neonatal outcome with respect to birth weight, Apgar score and perinatal death were better in the cases treated with nifedipine as compared to Isoxsuprine. (who.int)
  • No information is available on the relationship of age to the effects of isoxsuprine in geriatric patients. (slel.info)
  • To evaluate the effects of isoxsuprine and nicotine on TRAM. (bvsalud.org)
  • Some veterinarians have used isoxsuprine for the same purpose in broodmares, but its efficacy has not been scientifically established. (thehorse.com)
  • We conclude that isoxsuprine increases synthesis, storage, and release of surfactant in rabbit fetuses at 26 days gestation.Speculation: The effect of isoxsuprine to increase lung disaturated phosphatidylcholine synthesis which leads to an increase in total lung disaturated phosphatidylcholine is probably mediated through an increase in intracellular cyclic adenosine monophosphate. (semanticscholar.org)
  • Store isoxsuprine at room temperature away from moisture and heat. (rexhealth.com)