• Continued surveillance for C. auris , prudent antifungal use, and susceptibility testing for all C. auris clinical isolates (especially after patients have been treated with antifungal drugs) are needed. (cdc.gov)
  • The occurrence of these cases underscores the public health importance of surveillance for C. auris , the need for prudent antifungal prescribing, and the importance of conducting susceptibility testing on all clinical isolates, including serial isolates from individual patients, especially those treated with echinocandin medications. (cdc.gov)
  • The laboratory also performed antifungal susceptibility testing for azoles and echinocandins by broth microdilution and for amphotericin B, by E-test methods* as described previously, and categorized isolates as resistant based on CDC's tentative breakpoints ( 1 , 2 ). (cdc.gov)
  • A total of 110 clinical isolates of A. baumannii , collected in a recent 2-year period, were tested for carbapenem antibiotic susceptibility, followed by a molecular analysis of carbapenemase genes. (frontiersin.org)
  • Azasordarins: Susceptibility of Fluconazole-Susceptible and Fluconazole-Resistant Clinical Isolates ofCandida spp. (asm.org)
  • The purpose of this study was to evaluate the susceptibility of HSV isolated from normal subjects and patients with acquired immunodeficiency syndrome (AIDS) to ACV. (unboundmedicine.com)
  • The susceptibility of isolated HSV strains to various concentrations of ACV was determined by plaque reduction assay. (unboundmedicine.com)
  • One HSV-1 isolate from normal individuals had intermediate susceptibility. (unboundmedicine.com)
  • We analysed the clinical information, performed antimicrobial susceptibility testing, and conducted molecular epidemiological and genomic analyses on the isolates to identify patterns in the data. (biomedcentral.com)
  • CPE isolates were purified, and antimicrobial susceptibility tests performed. (biomedcentral.com)
  • All K. pneumoniae isolates were processed for antimicrobial susceptibility testing (AST) using the disk diffusion method. (tropmedres.ac)
  • However, limited information about disinfectant-susceptibility of multi-drug-resistant strain of M. tuberculosis was available. (biomedcentral.com)
  • We studied susceptibility of several Japanese isolates of multi-drug-resistant M. tuberculosis against disinfectants, which are commonly used in clinical and research laboratories. (biomedcentral.com)
  • We selected a laboratory reference strain (H37Rv) and eight Japanese isolates, containing five drug-susceptible strains and three multi-drug-resistant strains, and determined profiles of susceptibility against eight disinfectants. (biomedcentral.com)
  • This report summarizes trends in cephalosporin susceptibility among N. gonorrhoeae isolates in the United States during 2000--2010 using data from the Gonococcal Isolate Surveillance Project (GISP). (cdc.gov)
  • Because few isolates exhibited decreased susceptibility and increases in MICs can precede the emergence of resistance, the percentage of isolates with elevated MICs (≥0.25 µ g/mL for cefixime and ≥0.125 µ g/mL for ceftriaxone) was assessed to determine if MICs to cephalosporins were increasing with time. (cdc.gov)
  • The susceptibility of 115 pneumococcal isolates, recovered in a previous study, to six antimicrobials was determined by disk diffusion test. (edu.gh)
  • We performed anidulafungin, micafungin and caspofungin susceptibility testing according to the microdilution broth method on 240 Candida isolates collected in Polish hospitals. (edu.pl)
  • During January--June 2010, three Enterobacteriaceae isolates carrying a newly described resistance mechanism, the New Delhi metallo-beta-lactamase (NDM-1) ( 1 ), were identified from three U.S. states at the CDC antimicrobial susceptibility laboratory. (cdc.gov)
  • In all the samples, 50 E. coli strains were isolated and then assigned to serotyping, antimicrobial susceptibility test, detection of antimicrobial resistance genes and the Class 1 integrons, and multilocus sequence typing (MLST). (hindawi.com)
  • isolates among 94 outpatients and inpatients and see their grouping by phenotype characteristics (biofilm formation, frequency of serotypes, pigmentation, production of different class of beta-lactamases, and susceptibility to different antibiotic classes) and genotype. (ac.rs)
  • The antibiotic susceptibility rate showed that the mucoid strains compared to the non-mucoid were more resistant to nine out of 10 antibiotics. (scirp.org)
  • The aim of our present study was to screen P. aeruginosa strains isolated from ocular infections, for their potential to produce various phenotypic virulence factors and correlating them with biofilm formation and their antibiotic susceptibility profile. (springeropen.com)
  • There compare the susceptibility of H. pylori is evidence that most metronidazole-resist- isolates from Iranian patients to a range of ant strains have a mutation in the RDXA antimicrobials including furazolidone. (who.int)
  • Uganda.This study was designed to determine the distribution of bacterial pathogens isolated from septic post-operative wounds and their antimicrobial susceptibility patterns. (bvsalud.org)
  • the study sought to determine the antimicrobial susceptibility patterns of the major bacterial isolates to the first-line drugs used to treat UTIs at Rubaga hospital. (bvsalud.org)
  • Anti-fungal susceptibility profile of Candida spp isolates by the microdilution method. (bvsalud.org)
  • All isolates were susceptible to amphotericin B. With the newcutoffpoints,important variations were observed in the isolates susceptibility profiles,particularly inC. glabrata,supportingtheneedof species identification,permanentsurveillance ofthe isolatesresistancetoanti-fungalsand correlationof the sensitivityresultswith theclinicalresponseto treatment. (bvsalud.org)
  • Although extensive investigations failed to document transmission of pan-resistant isolates from the three patients to other patients or the environment, the emergence of pan-resistance is concerning. (cdc.gov)
  • A. baumannii is developing into multidrug resistant (MDR), extensively drug resistant (XDR), and pandrug resistant (PDR) bacteria, and its adaptation to the environment with drug resistance has previously been reported ( Durante-Mangoni and Zarrilli, 2011 ). (frontiersin.org)
  • Tuberculosis (TB) is one of the major causes of death related to antimicrobial resistance worldwide because of the spread of Mycobacterium tuberculosis multi- and extensively drug resistant (multi-drug resistant (MDR) and extensively drug-resistant (XDR), respectively) clinical isolates. (frontiersin.org)
  • To describe the epidemiological, phenotypical and genetic characteristics of clinical isolates carrying the optrA gene identified in antimicrobial resistance surveillance by the laboratory of the National Institute of Health of Colombia. (paho.org)
  • All the isolates analyzed by whole genome sequencing showed the resistance genes fexA, ermB , lsaA , tet(M) , tet(L) and dfrG in addition to optrA and were negative for other mechanisms of resistance to linezolid. (paho.org)
  • We aimed to describe the prevalence, phenotype, geographic variation, and sociodemographic predictors of ceftriaxone-resistance among E. coli isolates recovered from urine specimens. (monash.edu)
  • A commercially available new Genotype MTBDRplus assay was evaluated for its ability to detect mutations in Mycobacterial isolates conferring resistance to rifampicin (RMP) and isoniazid (INH). (nepjol.info)
  • Whole genome sequences of these isolates were determined and analysed to compute bacterial multilocus sequence types and plasmid replicon types, infer phylogenetic relationships, and identify antimicrobial resistance and virulence genes. (biomedcentral.com)
  • This study has revealed the genomic features of colonising CPE isolates, focusing on antimicrobial resistance and virulence determinants. (biomedcentral.com)
  • Under one-health perspective and the worldwide antimicrobial resistance concern, we investigate extraintestinal pathogenic Escherichia coli (ExPEC), uropathogenic E. coli (UPEC), and multidrug resistant (MDR) E. coli from 197 isolates recovered from healthy dogs in Spain between 2013 and 2017. (preprints.org)
  • This study aimed to investigate the prevalence of fluoroquinolone resistance and associated molecular characterization of S. dysenteriae 1 isolated from calves. (researchsquare.com)
  • According to the results of antimicrobial susceptibilities, 76.32% (29/38) of S. dysenteriae isolates were resistant to fluoroquinolone and showed multidrug resistance. (researchsquare.com)
  • 8 , 9 Furthermore, the accelerating accumulation and transmission of antimicrobial resistance genes (ARGs) among multidrug resistant (MDR) pathogens pose major difficulties in treating infections. (researchsquare.com)
  • Our analysis includes the antimicrobial resistance profiles, the molecular characterization of the mechanisms of resistance to fluoroquinolones, virulence gene profiles and the molecular characterization of S. dysenteriae isolates by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). (researchsquare.com)
  • In the same assay among 28 carbapenem nonproducing isolates, 9 (32.14%) isolates were positive for blaNDM-1 gene while none of them were tested positive for blaVIM gene.ConclusionsMolecular detection of resistant genes provides greater specificity and sensitivity than those with conventional techniques, thus aiding in accurate identification of antimicrobial resistance and clinical management of the disease. (tropmedres.ac)
  • While poultry constitutes the major industry in Nepal, there is a paucity of evidence on colistin resistance in Escherichia coli isolates causing natural infections in poultry. (tropmedres.ac)
  • This study aimed to explore the prevalence of plasmid-mediated colistin resistance gene, mcr-1 in E. coli isolated from liver samples of dead poultry suspected of E. coli infections. (tropmedres.ac)
  • Colistin resistance was determined by agar dilution method and colistin-resistant strains were further screened for plasmid-mediated mcr-1 gene, using conventional polymerase chain reaction (PCR). (tropmedres.ac)
  • Conclusion: The high prevalence of mcr-1 in colistin-resistant E. coli isolates in our study is a cause of concern for the probable coming emergence of colistin resistance in human pathogens, due to horizontal transfer of resistant genes from poultry to human isolates. (tropmedres.ac)
  • Geographic distribution of ceftriaxone resistance among urinary Escherichia coli isolates in Victoria ( a ) and the Greater Melbourne area (b). (biomedcentral.com)
  • Among the potential environmental isolates, there was no detection of any acquired antibiotic resistance, which supports the idea that their resistance mechanisms are mainly intrinsic. (cu.edu.eg)
  • On the contrary, the potentially pathogenic isolates presented a broad diversity of acquired antibiotic resistance toward different antibiotic classes. (cu.edu.eg)
  • All strains were isolated from canine infections and have different SCCmec elements and antibiotic resistance gene patterns. (pacb.com)
  • State and local public health departments should promote maintenance of laboratory capability to culture N. gonorrhoeae to allow testing of isolates for cephalosporin resistance. (cdc.gov)
  • MLST of 20 isolates showing resistance to at least four antimicrobials revealed a high diversity documented by 16 different clones, none of which had previously been associated with multidrug resistance. (edu.gh)
  • Antimicrobial resistance in S. aureus has increased dramatically, particularly in the hospital, where the rapid emergence of methicillin-resistant S. aureus (MRSA) and the appearance of S. aureus isolates with resistance to vancomycin have led to concern that this organism may become untreatable with currently available antimicrobials. (cdc.gov)
  • S. aureus isolates were screened for methicillin resistance following the NCCLS disk diffusion method. (cdc.gov)
  • Carbapenem resistance in all three of these isolates was detected in the course of routine testing. (cdc.gov)
  • Infection control interventions aimed at preventing transmission, as outlined in current guidance ( 5 ), should be implemented when NDM-1--producing isolates are identified, even in areas where other carbapenem-resistance mechanisms are common among Enterobacteriaceae . (cdc.gov)
  • Staphylococcus aureusis considered one of the most critical human pathogens worldwide, and its levels of methicillin resistance have increased even in strains isolated from people without nosocomial risk factors. (una.py)
  • Our results showed that farmed minks could be reservoirs of antimicrobial-resistant E. coli with Class 1 integron cassettes and resistance genes, which were likely to pose a threat to public health. (hindawi.com)
  • A correlation between DNA patterns and antibiotic resistance, production of pigments, serotypes distribution, and biofilm formation was not observed, and only confirmed higher genetic heterogeneity among P. aeruginosa isolates, which suggests that other molecular methods are needed to reveal potential relations between genotypic patterns and phenotypic characteristics. (ac.rs)
  • The high prevalence of ertapenem nonsusceptibility at a tertiary care hospital in Egypt was predominantly attributed to K. pneumoniae carbapenemase-mediated resistance mechanisms in K. pneumoniae isolates. (who.int)
  • In isolate SP1, linezolid resistance mediated by mutations in 23S rRNA and the L3 ribosomal protein was also detected. (univpm.it)
  • Conclusions: We showed that CRAB isolates positive result of carbapenemase-production and carbapenemase resistance genes of bla OXA-23 seem to be dominant in two tertiary care hospitals in Malang and Manado, Indonesia. (ui.ac.id)
  • Umar, U. , Anagor, S. , Aliyu, A. and Suleiman, A. (2016) Hypermucoviscosity in Clinical Isolates of Klebsiella pneumoniae Correlates with High Multiple Antibiotic Resistance (MAR) Index. (scirp.org)
  • The rise of antibiotic resistance among methicillin resistant Staphylococcus aureus (MRSA), have caused concerns for the treatment of MRSA infections. (biomedcentral.com)
  • Increasingly, clinical isolates of Pseudomonas are exhibiting multiple resistance to antibiotics and becoming pan drug resistant (XDR) [ 28 ]. (springeropen.com)
  • Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)
  • The objective of the current ering new classes of antimicrobials and the increasing study was, therefore, to assess the bacteriologic pro- emergence and reemergence of resistant pathogens, file, resistance pattern, and patient's outcome in Lan- mortality from infectious disease is increasing [1]. (who.int)
  • Rates of antimicrobial resistance (AMR) are increasing, as are rates of multidrug-resistant (MDR) and possible extensively drug-resistant (XDR) infections. (who.int)
  • In addition, long-read sequencing of one representative XDR ST235 isolate identified an integron carrying multiple resistance genes (including bla VIM-2), with differences in gene composition and synteny from the P. aeruginosa class 1 integrons described previously. (who.int)
  • P seudomonas aeruginosa is an opportunistic P. aeruginosa infections are often resistant to pathogen that often causes nosocomial infections treatment, 4 and carbapenem use has been strongly as- (e.g. pneumonia, bacteraemia and urinary sociated with resistance. (who.int)
  • were the reported increasing rates of resistance to antibiotics used second most common pathogen isolated from device- to treat P. aeruginosa infections, such as carbapenems associated HA infections in a study of intensive care and extended-spectrum cephalosporins ( Fig. 1A-B ). In units in Philippine hospitals. (who.int)
  • However, resistance zole-resistant strains of H. pylori . (who.int)
  • The patients were diag- resistance is believed to result from clonal nosed with ulcer (9), oesophagitis (18), Bar- selection of resistant variants rather than rett's oesophagus (15) and gastritis (28). (who.int)
  • El objetivo del estudio fue determinar la concentración inhibitoria mínima (CIM) del fluconazol y anfotericina B de aislados de Candida de pacientes ambulatorios y hospitalizados en Paraguay de mayo del 2010 a agosto del 2011, aplicando criterios nuevos y antiguos para el fluconazolYeast infections are very important because of their relatively high frequency and increased resistance to antifungal agents, especially to azole derivatives, and in particular, to fluconazole. (bvsalud.org)
  • The S. aureus becomes resistant by acquiring plasmids carrying genes for VANCOMYCIN RESISTANCE. (bvsalud.org)
  • Vancomycin‐intermediate S. aureus has low-level vancomycin resistance requiring an intermediate concentration of vancomycin between sensitive and resistant isolates. (bvsalud.org)
  • In the current study Gram-negative bacteria ( Escherichia, Enterobacter, Citrobacter, Proteus, Pseudomonas, and Klebsiella ) and the Gram-positive bacteria Staphylococcus were isolated from raw milk and biochemically characterized. (scielo.br)
  • We examined the clinical data from patients with CPE infections and their outcomes, concentrating on Klebsiella pneumoniae isolates. (biomedcentral.com)
  • Detection of NDM-1 and VIM Genes in Carbapenem-Resistant Klebsiella pneumoniae Isolates from a Tertiary Health-Care Center in Kathmandu, Nepal. (tropmedres.ac)
  • ABSTRACT The emergence and rapid spread of antibiotic-resistant Klebsiella pneumoniae isolates harbouring the blaKPC gene that encodes for carbapenemase production have complicated the management of patient infections. (who.int)
  • RÉSUMÉ L'émergence et la propagation rapide des souches de Klebsiella pneumoniae résistantes aux antibiotiques et porteuses du gène blaKPC codant la production de carbapénèmases ont compliqué la prise en charge des infections des patients. (who.int)
  • Here we describe a novel approach to develop an effective phage cocktail against a set of ESBL-producing E. coli and Klebsiella largely isolated from patients in United Kingdom hospitals. (sruc.ac.uk)
  • only Klebsiella species were significantly resistant (p0.05) to ciprofloxacin. (bvsalud.org)
  • Furthermore, several M. tuberculosis BDQ resistant mutants were isolated by both MDR strains, harboring mutations in both atpE and Rv0678 genes. (frontiersin.org)
  • The main objective of this study was to detect the carbapenem-resistant genes blaNDM-1 and blaVIM in K. pneumoniae isolated from different clinical specimens.MethodsA total of 585 clinical specimens (urine, pus, sputum, blood, catheter tips, and others) from human subjects attended at Annapurna Neurological Institute and Allied Sciences, Kathmandu were obtained in the period between July 2018 and January 2019. (tropmedres.ac)
  • On subsequent screening for resistant genes among carbapenemase-producers by PCR assay, 80% (24/30) and 3.33% (1/30) isolates were found to be positive for blaNDM-1 and blaVIM, respectively. (tropmedres.ac)
  • Pie chart, showing the distribution of the different type of genes and the number of isolates presented in G. anatis with the use of Roary software. (biomedcentral.com)
  • The antibiogram study revealed that Gram-negative bacteria were highly resistant to penicillin while Staphylococcus was resistant to streptomycin, amoxicillin, and lincomycin. (scielo.br)
  • This study is aimed at investigating biofilm and enterotoxin producing capacity of methicillin-resistant Staphylococcus aureus isolated from nostrils of healthy students of Delta State University Oleh campus. (ajol.info)
  • Determination of methicillin-resistant Staphylococcus aureus was carried out with the aid of Oxacillin sensitivity disc to test the presence of penicillin binding protein2a (PBP2a). (ajol.info)
  • The Methicillin-resistant Staphylococcus aureus (MRSA) isolates were screened to determine their biofilm producing ability using crystal binding assay. (ajol.info)
  • Complete genome sequences of three important methicillin-resistant clinical isolates of Staphylococcus pseudintermedius. (pacb.com)
  • We report the first complete genome sequences of three predominant clones (ST68, ST71, and ST84) of methicillin-resistant Staphylococcus pseudintermedius in North America. (pacb.com)
  • MRSA), intermediate to OX, and every 10th isolate sensitive to OX [i.e., methicillin-sensitive Staphylococcus aureus (MSSA)] by disk diffusion were saved for additional testing of organism characteristics. (cdc.gov)
  • Comparative molecular analysis of meticillin-resistant Staphylococcus aureus isolates from children with atopic dermatitis and healthy subjects in Taiwan. (bvsalud.org)
  • We now report our seminal findings on the major constituents including terpenes identified in native, historically significant herbal medicinal plant Elder (Sambucus nigra L.) flower and elder berry in particular and their concomitant strong antimicrobial effects exhibited on various nosocomial pathogens notably upon methicillin-resistant Staphylococcus aureus MRSA, recognised globally as a clinically significant pathogen, associated with skin and soft tissue infections. (researchgate.net)
  • Objectives: The objective of this study was to investigate the genetic environment of the cfr gene from two linezolid-resistant clinical isolates of Staphylococcus epidermidis from Italy. (univpm.it)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of healthcare-associated infections. (biomedcentral.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is involved in increasing number of serious infectious with high risk for morbidity and mortality and it is an important cause of healthcare-associated infections [ 1 ]. (biomedcentral.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) strains formed 25of this species. (bvsalud.org)
  • Isolates of the Staphylococcus aureus that are resistant to the antibiotic VANCOMYCIN. (bvsalud.org)
  • A tube coagulase test using rabbit plasma with EDTA was then performed on Staphaurex-negative isolates from BAP with morphology consistent with S. aureus and Staphaurex-positive isolates with morphology inconsistent with S. aureus (non-hemolytic). (cdc.gov)
  • Staphaurex-positive isolates and Staphaurex-negative tube coagulase-positive isolates were identified as S. aureus and saved for further testing. (cdc.gov)
  • To assess whether any relationship exists between nasal meticillin -resistant S. aureus ( MRSA ) colonization and subsequent skin and soft- tissue infections (SSTI). (bvsalud.org)
  • The aqueous extracts of T. alternifolia stem bark exhibited antibacterial activity against Gram-positive microorganisms, particularly against clinical isolates of MRSA and vancomycin resistant S. aureus (VRSA). (biomedcentral.com)
  • Estas cepas de S. aureus con una sensibilidad reducida a la vancomicina y a los antibióticos glucopeptídicos relacionados se observan a menudo en INFECCIONES HOSPITALARIAS. (bvsalud.org)
  • Globally, in 2018 about half a million TB infections were rifampicin-resistant, of which 78% were multi-drug resistant (MDR)-TB ( World Health Organization [WHO], 2019a ). (frontiersin.org)
  • The study was performed with an objective to compare Genotype MTBDRplus reverse hybridization probe assay (Hain Lifescince, GmBH, Nehern, Germany) with culture based proportion method for rapidly identifying MDR-TB strains from suspected multi drug resistant cases, referred to GENETUP Kathmandu, Nepal. (nepjol.info)
  • In the same assay, 76.4% (110/144) E. coli isolates were multi-drug resistant (MDR). (tropmedres.ac)
  • Multi-drug-resistant Mycobacterium tuberculosis has been an important problem in public health around the world. (biomedcentral.com)
  • However, poor information about disinfectant effectiveness against multi-drug-resistant (MDR) strain of M. tuberculosis is available. (biomedcentral.com)
  • The two M. tuberculosis MDR clinical isolates were firstly characterized by whole genome sequencing, finding the main mutations responsible for their MDR phenotype. (frontiersin.org)
  • Six isolates were selected to perform whole genome sequencing. (paho.org)
  • We selected 23 ST372 strains, 21 healthy dogs faecal isolates and two human clinical isolates for whole genome sequencing and built a SNP-tree with these 23 genomes and 174 genomes (128 from canine strains and 46 from human strains) obtained from public databases. (preprints.org)
  • Therefore, an antibiotic-sensitive isolate PA30 and a multi-resistant isolate PA49 originating from waste waters were compared via whole genome and transcriptome Illumina sequencing after exposure to municipal waste water and tap water. (kit.edu)
  • Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and infection control challenge. (frontiersin.org)
  • Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is an important pathogenic bacterium that can cause nosocomial infection in hospitalized patients with various manifestations. (ui.ac.id)
  • Multidrug-resistant Acinetobacter spp. (who.int)
  • Percentage of invasive isolates of Acinetobacter spp. (who.int)
  • Altogether, 88.9% (40/45) of the CPE isolates were K. pneumoniae . (biomedcentral.com)
  • The most abundant carbapenemase gene family in the K. pneumoniae isolates (33/39) was bla OXA-232 , with bla NDM-1 additionally identified in 19 of them. (biomedcentral.com)
  • The specimens were isolated and identified for K. pneumoniae. (tropmedres.ac)
  • Thus, confirmed carbapenemase-producing isolates were further screened for the production of blaNDM-1 and blaVIM using conventional polymerase chain reaction (PCR).ResultsAmong the clinical isolates tested, culture positivity was 38.29% (224/585), and the prevalence of K. pneumoniae was 25.89% (58/224). (tropmedres.ac)
  • This study in a tertiary care hospital in Egypt used real-time PCR assay to test ertapenem-nonsusceptible isolates of K. pneumoniae for the presence of the blaKPC gene and compared the results with modified Hodge test. (who.int)
  • From the 45 non-duplicate isolates of K. pneumoniae recovered from different clinical specimens, a high prevalence of ertapenem-nonsusceptible isolates (44.4%) was reported using the new lower CLSI breakpoints. (who.int)
  • La présente étude menée dans un hôpital de soins tertiaires en Égypte a utilisé la méthode de PCR en temps réel pour évaluer la présence du gène blaKPC dans les isolats de K. pneumoniae non sensibles à l'ertapénème, puis a comparé les résultats à l'aide du test de Hodge modifié. (who.int)
  • There are few data regarding non-invasive ceftriaxone-resistant E. coli (CR-EC) isolates in the Australian community. (monash.edu)
  • Methods: In August 2017, we prospectively analysed E. coli isolates recovered from urine specimens submitted to Dorevitch Pathology (Victoria, Australia), a laboratory that services patients in the community and hospitals. (monash.edu)
  • Results: We included 6732 non-duplicate E. coli isolates. (monash.edu)
  • Molecular Characteristics of Extraintestinal Pathogenic E. coli (ExPEC), Uropathogenic E. coli (UPEC), and Multidrug Resistant E. coli Isolated from Healthy Dogs in Spain. (preprints.org)
  • All these findings suggest that dogs are reservoirs of ExPEC, UPEC and MDR E. coli isolates with zoonotic potential. (preprints.org)
  • 109/202) of E. coli isolates was obtained in the liver samples from poultry birds (of both types) aged less than forty days. (tropmedres.ac)
  • In AST, 95.1% (137/144) and 82.6% (119/144) of E. coli isolates were resistant against tetracycline and ciprofloxacin, respectively, while 13.2% (19/144) and 25.7% (37/144) isolates were resistant to cefoxitin and imipenem, respectively. (tropmedres.ac)
  • Scale represents percentage of E. coli isolates that are resistant to ceftriaxone. (biomedcentral.com)
  • Compared with 340 human E. coli STs reported in China, the ST10 clonal complex, known as the largest human clonal complex, was also found in the 50 mink E. coli isolates. (hindawi.com)
  • The treatment of pathogenic E. coli infections is becoming complicated because of the rapid emergence and dissemination of antibiotic-resistant strains, which may consequently result in an increasing number of clinical treatment failures in bacterial-mediated diseases and further threaten public health with the possibility of transmission to humans through aerosols, environmental contact or other methods [ 2 , 6 ]. (hindawi.com)
  • The ESBL E. coli collection had six isolates from the prevalent UTI-associated ST131 sequence type, five of which were targeted effectively by the final cocktail. (sruc.ac.uk)
  • Conclusion High number of resistant microorganisms was isolated, and increased mortality was documented from infections caused by carbapenem-resistant bacteria. (who.int)
  • The main goal of the present paper was to perform microbiological investigations to culturable bacteria isolated from uranium ore samples from Aborshid Egypt, and characterize their response to 15 antibiotics and 10 heavy metals beside uranium. (cu.edu.eg)
  • It was concluded that highly metal-resistant bacteria could be used with potential application for treatment of wastewaters. (cu.edu.eg)
  • especially the multidrug-resistant bacteria are a serious and fatal problem in the intensive care unit. (springeropen.com)
  • The minimum inhibitory concentration was 1 mg/ml against multidrug-resistant bacteria, and LC50 was 62.307 μg/ml on the hepatocellular carcinoma cell line. (springeropen.com)
  • Microbial-synthesized silver nanoparticles have a potential application to combat multidrug-resistant bacteria, especially in the intensive care unit. (springeropen.com)
  • Multidrug-resistant (MDR) bacteria are a serious and fatal problem in the intensive care unit (ICU). (springeropen.com)
  • Multi-resistant hospital bacteria linked to India and Pakistan. (cdc.gov)
  • Extended-spectrum beta-lactamase produc- ing Enterobacteriaceae was found in 37.5% (54) isolates and carbapenem resistant bacteria were identified in 27.8% of patients. (who.int)
  • Age 65 years, presence of septic shock, and presence of carbapenem-resistant bacteria were independently associated with in- creased in-hospital mortality. (who.int)
  • Resistant bacteria may be present from the commencement of the infection or may develop during treatment. (bvsalud.org)
  • Latex agglutination test was carried out to detect the presence of enterotoxins among the MRSA isolates. (ajol.info)
  • All the MRSA isolates tested for the presence of biofilm showed positive results. (ajol.info)
  • From 2005 through 2006, comparative molecular analyses of 23 MRSA -colonizing isolates from 133 children with AD, 44 MRSA -colonizing isolates from 490 healthy controls, and 12 MRSA -infecting isolates from 20 children with AD and concurrent SSTI were conducted. (bvsalud.org)
  • The molecular characteristics differed significantly between the MRSA isolates from children with AD and the MRSA -colonizing isolates from healthy controls. (bvsalud.org)
  • Analysis of our data provides evidence that links MRSA -colonizing isolates to MRSA -infecting isolates from concurrent SSTI in children with AD. (bvsalud.org)
  • Isolates of MRSA not belonging to the Brazilian Epidemic Clone (BEC) are colonizing and infecting patients at the hospital. (biomedcentral.com)
  • We found that is possible a MRSA genetic diversity in Brazil, when strains of MRSA not belonging to the Brazilian Epidemic Clone (BEC) that were isolated in patients at the hospital. (biomedcentral.com)
  • Twenty-one MRSA strains were isolated from nasal carriers (in the SDUs) and two MRSA strains obtained from patients with bloodstream infections (in the ICU). (biomedcentral.com)
  • All MRSA isolates from nasal cultures were typed by pulsed-field gel electrophoresis (PFGE). (biomedcentral.com)
  • Blood culture isolates showed MRSA harbouring SCCmec type II with a PFGE profile similar to the New-York Japan clone, also observed in bloodstream isolates from other hospitals (fig 1 ). (biomedcentral.com)
  • Candida auris is an emerging yeast that is often drug-resistant. (cdc.gov)
  • Thus, CC92 A. baumannii carrying OXA-23 is a major drug-resistant strain spreading in China. (frontiersin.org)
  • Among these cases, 6.2% were estimated to have extensively drug-resistant (XDR)-TB ( World Health Organization [WHO], 2019a ). (frontiersin.org)
  • Here we report the complete genome sequence of an extensively drug-resistant, Verona integron-encoded metallo-ß-lactamase-expressing isolate belonging to the high-risk sequence type 233. (pacb.com)
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
  • The emergence of ACV-resistant strains has been frequently reported as a result of long-term ACV therapy. (unboundmedicine.com)
  • Alternative antiherpetic agents should be employed to control and reduce the emergence of ACV-resistant strains in patients with AIDS. (unboundmedicine.com)
  • Given the increased common emergence of multidrug resistant isolates, uninterrupted surveillance will be necessary to understand the actual epidemic burden and control this infection. (researchsquare.com)
  • CDC asks that carbapenem-resistant isolates from patients who have received medical care within 6 months in India or Pakistan be forwarded through state public health laboratories to CDC for further characterization. (cdc.gov)
  • The inclusion of an automated fragment analysis method led to the characterization of isolates, improving response time, and maintaining high sensitivity compared to the manual process. (una.py)
  • Candida auris is a globally emerging yeast that causes outbreaks in health care settings and is often resistant to one or more classes of antifungal medications ( 1 ). (cdc.gov)
  • The number of infections caused by Candida species resistant to fluconazole, which is applied as the first line drug in candidiasis treatment, increases every year. (edu.pl)
  • The objective of this study was to determine the minimum inhibitory concentration (MIC) of fluconazole and amphotericin B in Candida isolates in clinically significant samples from hospitalized patients in Paraguay from May 2010 to August 2011 using the old and new criteria for fluconazole. (bvsalud.org)
  • Only two isolates produced ESBL, eight were carbapenemase producers, and five isolates produced MBLs. (ac.rs)
  • krusei(4%).Usingthe old cutoff,five isolates were resistant to fluconazole (10%), two naturally resistant isolates (C. krusei), twoC. (bvsalud.org)
  • The present study aimed to determine the effectiveness of five essential oils (EOs) against multidrug-resistant foodborne pathogens. (scielo.br)
  • Background: Ceftriaxone-resistant Enterobacteriaceae are priority pathogens of critical importance. (monash.edu)
  • Shigella is one of the major pathogens that causes diarrheal diseases in humans and animals.1,2 Since the first highly toxigenic species, Shigella dysenteriae, was isolated in 1898,3 four species has been described in Shigella genus, and each subgroup can be divided into multiple subtypes according to biochemical and serological properties. (researchsquare.com)
  • An evidence-based scientific scrutiny of Irish traditional medicines for their antimicrobial potency is urgently required for combating antibiotic resistant common nosocomial pathogens. (researchgate.net)
  • Objectives: The objective of this study was to isolate and identify the major bacterial pathogens of symptomatic and asymptomatic UTIs among patients at Rubaga hospital. (bvsalud.org)
  • Twenty-eight (14.2%) isolates were classified as MDR, associated with B1, D and E phylogroups and included 24 clones, of which eight had also been identified among human isolates causing infections. (preprints.org)
  • Methods: A. baumannii isolates collected from patient's clinical cultures in two tertiary care hospitals in Malang and Manado were included. (ui.ac.id)
  • Methods: A. baumannii isolates collected from patient{\textquoteright}s clinical cultures in two tertiary care hospitals in Malang and Manado were included. (ui.ac.id)
  • To achieve this, we assessed four different methods to assess phage virulence across these bacterial isolates. (sruc.ac.uk)
  • Sixty-seven of the 110 isolates (60.9%) were resistant to carbapenems, 80.60% (54/67) of which carried the bla OXA-23 gene. (frontiersin.org)
  • The optrA gene was confirmed in 23/25 isolates of E. faecalis from seven departments in Colombia. (paho.org)
  • The MTBDRplus assay detected 59 of 61 RMP resistant strains (96.72%) with mutations on 81-bp hot spot region of rpoB gene and 60 of 63 INH resistant strains (95.23%) with mutation in codon 315 katG and regulatory region of inhA. (nepjol.info)
  • All 29 fluoroquinolone-resistant isolates were positive for the aac(6')-Ib-cr gene but negative for qepA , except SD001. (researchsquare.com)
  • In addition, only 6 (20.69%, 6/29) isolates harbored the qnr gene, including two with qnrB (6.90%, 2/29) and four with qnrS (13.79%, 4/29). (researchsquare.com)
  • The blaKPC gene was confirmed in 14/20 (70.0%) of these isolates. (who.int)
  • The isolates were identified by 16S rRNA gene sequencing. (biomedcentral.com)
  • Antimicrobial resistant microorganisms are found in people, animals and the environment and can spread globally. (who.int)
  • P. aeruginosa strains were isolated from 46 patients with conjunctivitis (2), endophthalmitis (11) and active keratitis (25) seen at our Institute, between 2016 and 2020. (springeropen.com)
  • P. aeruginosa isolates referred to the ARSP, epidemic clone. (who.int)
  • In this study, we aimed to investigate the epidemiology and molecular characteristics of S. dysenteriae isolates from cattle farms in Gansu, China. (researchsquare.com)
  • According to MLST and PFGE analysis, these isolates were separated into 4 and 28 genotypes, respectively. (researchsquare.com)
  • MLST analysis showed that 32 sequence types (STs) were identified, while ST46 was the predominant genotype among all isolates. (hindawi.com)
  • During that period, the percentage of isolates with elevated minimum inhibitory concentrations (MICs) to cephalosporins (≥0.25 µ g/mL for cefixime and ≥0.125 µ g/mL for ceftriaxone) increased from 0.2% in 2000 to 1.4% in 2010 for cefixime and from 0.1% in 2000 to 0.3% in 2010 for ceftriaxone. (cdc.gov)
  • MICs to cephalosporins (cefixime and ceftriaxone) among gonococcal isolates collected during 2000--2010 were analyzed. (cdc.gov)
  • The percentage of isolates with ceftriaxone MICs ≥0.125 µ g/mL increased from 0.1% to 0.3% during 2000--2010 (p = 0.047). (cdc.gov)
  • Genetic relatedness of the isolates was characterized by multilocus sequence typing. (frontiersin.org)
  • The genetic environment of the optrA-2 (ST16) isolates presented the impB, fex, optrA segment, associated with plasmid, while in two isolates ( optrA-6 and optrA-5 ) the transferable chromosomal element Tn6674-like was found. (paho.org)
  • OptrA -positive clinical isolates present a high genetic diversity, with different optrA clones and variants related to two types of structures and different mobile genetic elements. (paho.org)
  • All CPE isolates carrying either bla OXA-232 or bla NDM-1 were resistant to meropenem, but only 40 from 45 were susceptible to colistin. (biomedcentral.com)
  • Overall, 90.4% of isolates were intermediate penicillin resistant, 99.1% were trimethoprim resistant, 73.0% were tetracycline resistant, and 33.9% were sulfamethoxazole resistant. (edu.gh)
  • This study compared the in vitro efficacy of furazolidone with metronidazole, clarithromycin, amoxicillin and tetracycline in 70 H. pylori isolates from dyspeptic patients. (who.int)
  • Wadsworth Center, the New York State public health laboratory, conducted testing to confirm presumptive C. auris isolates from various health care facilities in New York during August 2016-June 2019 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, using both the manufacturer's and in-house validated library databases. (cdc.gov)
  • Between October 2014 and February 2019, 25 isolates of Enterococcus spp . (paho.org)
  • Overall, AST detected 60.34% (35/58) carbapenem-resistant isolates, while the MHT phenotypically confirmed 51.72% (30/58) isolates as carbapenemase-producers and 48.28% (28/58) as carbapenemase nonproducers. (tropmedres.ac)
  • Current CDC infection control guidance for carbapenem-resistant Enterobacteriaceae also is appropriate for NDM-1--producing isolates ( 5 ). (cdc.gov)
  • This includes recognizing carbapenem-resistant Enterobacteriaceae when cultured from clinical specimens, placing patients colonized or infected with these isolates in contact precautions, and in some circumstances, conducting point prevalence surveys or active-surveillance testing among other high-risk patients. (cdc.gov)
  • Clinicians should be aware of the possibility of NDM-1--producing Enterobacteriaceae in patients who have received medical care in India and Pakistan, and should specifically inquire about this risk factor when carbapenem-resistant Enterobacteriaceae are identified. (cdc.gov)
  • Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. (cdc.gov)
  • A target panel of 38 ESBL-producing clinical strains isolated from urine samples was collated and used to test phage efficacy. (sruc.ac.uk)
  • however, in patients with AIDS, the prevalence of ACV-resistant strains is remarkable (P = 0.001). (unboundmedicine.com)
  • Sensitivity testing was done on the isolates using the disk diffusion method. (bvsalud.org)
  • Eight CR-EC isolates (2.4%) were susceptible only to amikacin, meropenem and nitrofurantoin. (monash.edu)
  • A total of 64 MDR isolates (i.e., at least resistant to RMP and INH), 5 fully susceptible strains and 1 RMP sensitive strains by conventional proportion method were analyzed using Genotype MTBDRplus assay. (nepjol.info)
  • In the PCR assay, 43.9% (18/41) of colistin-resistant isolates were screened positive for plasmid-mediated mcr-1. (tropmedres.ac)
  • Among 1,158 isolates col- and fluconazole-susceptible dose-dependent (F-SDD) lected during multicenter studies in South Korea during isolates ( 7 , 13 , 14 ), which can impede determination of 2008-2018, 5.7% were FR. (cdc.gov)
  • For 64 patients with FR whether specific Pdr1p AAS result in fluconazole re- bloodstream infection isolates, the 30-day mortality rate sistance. (cdc.gov)
  • The MLVA automation included the typing of 88% (22/25) isolates, resulting in 3 different profiles, each one associated with a different spa type, being the 1-t019 the predominant (86%), followed by the 3-t002 profile (9%), yielding 100% concordance with the MLVA manual, as well as high concordance with the standard gold method, PFGE. (una.py)
  • Identifications of meropenem-resistant A. baumannii isolates with the vitek2® system results, followed by a sensitivity test using 10 µg imipenem antibiotic disc according to CLSI guidelines to fulfill the criteria as CRAB isolates. (ui.ac.id)
  • The widespread distribution of antimicrobial-resistant Shigella has become a recurrent challenge in many parts of the developing world. (researchsquare.com)
  • Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections including pneumonia. (wikipedia.org)