Isolates of candida glabrata. Medical search. Frequent questions

Furthermore, Candida tropicalis infection has also increased in frequency. (medscape.com)
RESULTS: Ninety-five yeasts isolates were analyzed, including 40 Candida albicans, 31 Candida glabrata, 24 Candida tropicalis. (who.int)
The isolated yeasts were: Candida albicans (sixty-two isolates), Candida tropicalis (four isolates), Candida glabrata (two isolates), Candida parapsilosis (two isolates), Candida krusei (one isolate) and Trichosporon pullulans (one isolate). (scielo.br)
Foram isoladas leveduras em setenta e duas amostras clínicas, sendo sessenta e duas de Candida albicans, quatro de C. tropicalis, duas de C. glabrata, duas de C. parapsilosis, uma de C. krusei e uma de Trichosporon pullulans. (scielo.br)
However, over the past decades the incidence of infections caused by other Candida species including C. tropicalis, C. glabrata, C. krusei and other genera such as Trichosporon and Cryptococcus has been reported (6,9,21). (scielo.br)
Candida albicans Candida glabrata Many isolates are intermediately susceptible Candida parapsilosis Candida tropicalis Cryptococcus neoformans The following in vitro data are available. (ultimateunderground.com)
Objective: A large proportion of vulvovaginal candidiasis (VVC) in diabetes is due to non-albicans Candida species such as C. glabrata and C. tropicalis. (ias.ac.in)
Candiduria was caused by Candida albicans, C. glabrata, and C. tropicalis. (bvsalud.org)
Among the vaginal specimens, 108 out of 189 Candida isolates were identified as C. albicans, C. glabrata, C. kefyr, C. parapsilosis, and C. tropicalis. (ac.ir)
two Candida eremophila isolates were identified as Candida glabrata and Can-dida tropicalis, and one Saprochaete clavata isolate was identified as Saprochaete capitata. (karatay.edu.tr)
Other species, such as Candida tropicalis and Candida stellatoidea , more often appear in persons who are severely immunocompromised. (medscape.com)
Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis and C. guilhermondii were seeded into antibacterial (cefepime, meropenem, vancomycin, and piperacillin- tazobactam) gradient plates produced in Mueller-Hinton Agar. (bvsalud.org)

however, Candida glabrata and Candida parapsilosis tend to be the most common isolates after Candida albicans in invasive candidiasis. (medscape.com)
however, unlike in North America, C parapsilosis is the second most common Candida species in many Latin American countries. (medscape.com)
We do occasionally see outbreaks mainly with a species called Candida parapsilosis , but these outbreaks are actually very rare. (cdc.gov)
Antifungal resistance is an increasing problem with fungal species from the Candida genus, particularly, Candida auris, Candida glabrata and Candida parapsilosis. (qub.ac.uk)
C. albicans, C. parapsilosis complex and C. kefyr isolates did not show resistance. (injectormedicaljournal.com)

Comparison of antimycotic activity of originator and generics of voriconazole and anidulafungin against clinical isolates of candida albicans and candida glabrata. (mci.edu)
Yeasts were isolated from seventy-two out of one hundred and eight clinical samples. (scielo.br)
Considering the increasing number of cases of AIDS in Pernambuco, Brazil, and the susceptibility to opportunistic mycosis, the objective of this study was to isolate and identify yeasts in clinical samples of AIDS patients. (scielo.br)
Sildenafil Viagra, defined as a complete resolution of signs and symptoms of vaginal candidiasis clinical cure along with a negative KOH examination and negative culture for Candida microbiologic eradication was 55 in both the fluconazole group and the vaginal products group. (ultimateunderground.com)
Invasive candidiasis (IC) is a clinical condition that is not associated with a single Candida species. (encyclopedia.pub)
The secondary outcomes were the mycological cure in C. albicans VVC, overall mycological cure irrespective of the type of Candida species, frequencies of yeast on direct microscopy, and clinical symptoms and signs of VVC on the 15th day of treatment. (ias.ac.in)
En mayo de 2007 obtuve el Certificate of Training in Molecular Biological Techniques en el Department of Molecular Biology y desde Junio de 2008 a Junio de 2009 completé el Certificate in Clinical Research en el Center for Translational Science Activities en Mayo Clinic College of Medicine, Rochester Minnesota. (unav.edu)
Un 40% de esos trabajos han sido publicados en revistas del primer cuartil entre las que destacan New England Journal of Medicine, Lancet, Lancet Infectious Diseases, Clinical Infectious Diseases, Clinical Microbiology Reviews, Antimicrobial Agents and Chemotherapy, Journal Clinical Microbiology, Journal Antimicrobial Chemotherapy, Mayo Clinic Proceedings y Malaria Journal. (unav.edu)
Mating genotypes and susceptibility profiles of clinical isolates of Candida glabrata from Turkey. (cdc.gov)
Objective: Systematic investigation of clinical outcome and microbiological features of yeast isolates recovered from the oral cavity of 150 Iranian patients with hematological malignancies. (opathy.eu)
The practical applicability of the assay, reported here as MS-AFST, was assessed with a panel of clinical isolates that were selected to represent phenotypically and genotypically/molecularly susceptible or resistant strains. (researchwithrutgers.com)
However, cell growth kinetics in the presence of anidulafungin revealed important cues about the in vitro fitness of C. glabrata isolates, which may lead to genotypic or phenotypic antifungal testing in clinical practice. (researchwithrutgers.com)
The LAMP specificity assay accurately detected C. glabrata with no cross-reactivity with other Candida or mould clinical isolates tested. (upm.edu.my)
Antimicrobial susceptibility and prevalence of extended-spectrum beta-lactamases in clinical strains of Klebsiella pneumoniae isolated from pediatric and adult patients of two Polish hospitals. (krakow.pl)
These results suggest that triple mutations in clinical isolates of A baumannii contribute to the development of high levels of resistance to fluoroquinolones and that mutations in parC S80L or E84K (groups II and VII) may contribute to alterations in efflux pump activity in A baumannii . (ophrp.org)
Therefore, this study aims to assess the main bacterial isolates in blood cultures and a possible change in their sensitivity profiles in a clinical analysis laboratory in Fortaleza, Ceará. (bvsalud.org)
In C. glabrata clinical isolates, the predominant mechanism behind azole resistance is upregulated expression of multidrug transporter genes CgCDR1 and CgPDH1 . (uthsc.edu)
In an azole-resistant clinical isolate, PDR1 disruption reduced azole MICs eight- to 64-fold with no effect on sensitivity to other antifungals. (uthsc.edu)
We next examined the genome-wide gene expression profiles in four matched azole-susceptible and -resistant clinical isolate sets of C. glabrata in which CgCDR1 gene expression was upregulated in the resistant isolate. (uthsc.edu)

Candida is the third or fourth most common cause of nosocomial bloodstream infection in the United States, accounting for 8%-10% of all bloodstream infections. (medscape.com)
[ 1 ] There is an increasing shift toward infections caused by non- albicans Candida species, which now cause 40%-60% of reported cases. (medscape.com)
In Europe, Candida species are the sixth to tenth most common cause of bloodstream infections. (medscape.com)
Echinocandins are the first-line therapy for treatment of invasive Candida infections, but the mortality rate remains high, calling for novel strategies. (dovepress.com)
Single caspofungin doses used in mice in this study are attainable in humans as well, suggesting a potential place of this dosing strategy not only in prevention but also in curative treatment of evolved invasive Candida infections. (dovepress.com)
The frequency of invasive Candida infections has increased worldwide in the last decades. (dovepress.com)
1 - 5 The mortality rate of invasive Candida infections is around 40%, but in intensive care units, 50-75% mortality rates were observed among critically ill patients even in case of C. albicans despite the introduction of echinocandins into the antifungal armamentarium. (dovepress.com)
6 - 8 This antifungal class shows excellent in vitro and in vivo activity against Candida species and has quickly become the first therapeutic choice for the treatment of candidemia and other forms of invasive Candida infections. (dovepress.com)
The most common type of fungus in humans is called Candida albicans and causes commonly occurring infections in women's genitals. (wellnessresources.com)
Furthermore, such drug tolerant cells are readily isolated from patients with recurrent Candida infections (3). (findaphd.com)
BACKGROUND: Urinary Candida infections in the hospital environment are frequent and need to be better understood. (who.int)
AIMS: To compare the results of antifungal susceptibility profiles of yeasts isolated from patients with urinary infections obtained by broth microdilution method (BM) and by disk diffusion (DD), and also evaluate the capacity of these yeasts to form biofilms. (who.int)
Even when there is a broad range of antifungals drugs for Candida infections, azoles, polyenes, and echinocandins are considered among the most effective treatment. (intechopen.com)
Candidemia, which is the bloodstream manifestation of fungal infections due to Candida , turns out in recent studies that we've looked at are the most common if not some of the most common healthcare associated bloodstream infections in our country, in the United States. (cdc.gov)
The risk factors for candid are sometimes we call in the fungal world the other C. diff , have somewhat similar characteristics in that broad spectrum antibacterial use is a very common association with those who develop infections due to Candida . (cdc.gov)
As I mentioned, source of infections due to Candida generally we think, and from conventional wisdom, that these are really auto infections with our own host gut flora. (cdc.gov)
C. glabrata is particularly concerning as it exhibits intrinsic resistance to fluconazole, the first line of defense in treating Candida infections, and isolates have acquired resistance to a second class of antifungal drugs, echinocandins. (qub.ac.uk)
The highly transmissible C. auris also poses a global threat to human health as >90% of all C. auris infections are resistant to at least one antifungal, with >30% infections showing multi-drug resistance and certain isolates being pan-resistant to all known therapies. (qub.ac.uk)
This project will explore the potential of antifungal peptides (AFPs) as powerful candidates to combat resistant candida infections due to their efficacy and high selectivity. (qub.ac.uk)
The global epidemiology of invasive Candida infections - is the tide turning? (microbiologyresearch.org)
Management and outcome of bloodstream infections due to Candida species in England and Wales. (microbiologyresearch.org)
Candida species commonly cause invasive nosocomial infections in immunocompromised patients [ 5 ] . (encyclopedia.pub)
Bloodstream infections (BSIs) caused by Candida species or candidaemia are the most common manifestation of invasive candidiasis. (biomedcentral.com)
Among the patients with solid tumours and infections caused by NCAC species, 53.8% were caused by C. glabrata . (biomedcentral.com)
In addition, C. glabrata was the main aetiological agent of 63.7% of SOT patients with NCAC infections. (biomedcentral.com)
Because of the inherent immunosuppression of cancer patients opportunistic infections by Candida spp, occur frequently. (biomedcentral.com)
Cancer patients with metastasis have a high probability of mucocutaneous and bloodstream infections by fungi, including Candida species. (biomedcentral.com)
Azole antifungal resistance has emerged as a significant problem in the management of infections caused by fungi including Candida species. (uthsc.edu)
In recent years, Candida glabrata has become the second most common cause of mucosal and invasive fungal infections in humans second to Candida albicans . (uthsc.edu)
Not only are systemic C. glabrata infections characterized by high mortality rates, treatment failures to the azole class of antifungals, the most widely used antifungal for treatment of C andida infections, have been reported. (uthsc.edu)
El objetivo del estudio fue determinar la concentración inhibitoria mínima (CIM) del fluconazol y anfotericina B de aislados de Candida de pacientes ambulatorios y hospitalizados en Paraguay de mayo del 2010 a agosto del 2011, aplicando criterios nuevos y antiguos para el fluconazolYeast infections are very important because of their relatively high frequency and increased resistance to antifungal agents, especially to azole derivatives, and in particular, to fluconazole. (bvsalud.org)
however, Nakaseomyces glabrata ( C. glabrata ) and other non-albicans species are increasingly involved in fungemia, urinary tract infections, and, occasionally, other focal disease. (msdmanuals.com)
Candida species are a major cause of systemic fungal infections and are the most common cause of fungal infections in patients who are immunocompromised. (msdmanuals.com)

C glabrata and C krusei have been identified as common causes of candidemia in patients with hematologic malignancies. (medscape.com)
krusei(4%).Usingthe old cutoff,five isolates were resistant to fluconazole (10%), two naturally resistant isolates (C. krusei), twoC. (bvsalud.org)
Other species, including Candida krusei , have appeared in persons who are severely immunocompromised. (medscape.com)

Candida is a unicellular yeast whose cells reproduce by budding. (medscape.com)
Here, we analyzed 40 pathogenic isolates of a haploid and asexual yeast, Candida glabrata, for their genome structure and stability. (wellnessresources.com)
A yeast named Candida glabrata commonly occurs in humans, usually on our skin. (wellnessresources.com)
Candida glabrata has become the second most common yeast pathogen in humans. (wellnessresources.com)
This project aims to characterize the tolerant state in the clinically relevant yeast, Candida glabrata, and determine whether it is determined by genetic and/or epigenetic mechanisms. (findaphd.com)
Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill patients. (encyclopedia.pub)
Candida glabrata is an asexual, haploid yeast of the clade Nakaseomyces. (encyclopedia.pub)
Antifungal susceptibility testing (broth microdilution, CLSI M27-A3/S4) and genotypic diversity of yeast isolates (amplified fragment length polymorphism) were assessed. (opathy.eu)
Candida albicans (80.3%) and Kluyveromyces marxianus (C. kefyr) (12.7%) were the two most prevalent yeast species isolated. (opathy.eu)
Fluconazole resistance can develop in a single persistent strain of yeast, but more commonly fluconazole resistance results from emergence of a different Candida albicans strain or another Candida species. (grantome.com)
Methods: The CHROMagar Candida™ Medium (CC) for yeast culture and exfoliative cytology was used to identify colonization by Candida spp. (bvsalud.org)
RESULTS Yeast species, predominantly candida, were identified in the stools of 43 children (39%) with diarrhoea and 26 (36%) without diarrhoea. (bmj.com)
Candida species form a ubiquitous genus of yeast present throughout the environment. (bmj.com)
6 C albicans is the most common yeast species isolated from human faeces, being identified in 65% of stool samples from healthy adults. (bmj.com)
A prospective, hospital based study was carried out to assess the prevalence and concentrations of candida and other yeast species in the stools of hospitalised children with and without diarrhoea. (bmj.com)

The pathogenic fungi Candida albicans and Candida glabrata are obligate human commensals that can cause disease when host immune systems are compromised. (findaphd.com)

Candida albicans is the most common fungal species causing denture stomatitis, and oral candidiasis has been reported in 24 to 60% of denture wearers. (thieme-connect.de)
Candida albicans is an opportunistic fungal pathogen that is the principal cause of superficial and systemic candidiasis in human and animals. (scialert.net)
The isolation of species of Candida in oral candidiasis has been shown to increased with the advance of HIV infection. (scielo.br)
It is the second most isolated Candida species associated with invasive candidiasis (IC) behind C. albicans. (encyclopedia.pub)
Invasive candidiasis due to C. glabrata causes substantial morbidity and mortality of approximately 40-60%, perhaps due to the inherent low susceptibility of C. glabrata to the most commonly used azoles [ 3 ] . (encyclopedia.pub)
In recent years, a shift of predominance from C. albicans to non- C. albicans Candida (NCAC) species has been observed, and C. albicans now accounts for only half of the invasive candidiasis cases reported [ 9 ]. (biomedcentral.com)
2014) reported that invasive candidiasis caused by C. glabrata is most commonly associated with patients who receive treatment for solid tumours or undergo solid organ transplantation (SOT) [ 15 ]. (biomedcentral.com)
Resistance to antifungal drugs is increasing among Candida isolates from patients with vulvovaginal candidiasis (VVC). (ac.ir)
It would be a useful tool speeding management of C. glabrata invasive candidiasis patients through POCT approach. (upm.edu.my)
Higher doses of fluconazole are more effective against resistant strains in murine candidiasis, but the utility of identifying resistant isolates and treating resistant yeasts with high doses of fluconazole is not established. (grantome.com)
Candidiasis is infection by Candida species (most often C. albicans ), manifested by mucocutaneous lesions, fungemia, and sometimes focal infection of multiple sites. (msdmanuals.com)
Etiology Candidiasis is skin and mucous membrane infection with Candida species, most commonly Candida albicans . (msdmanuals.com)
Disseminated candidiasis Candidiasis is infection by Candida species (most often C. albicans ), manifested by mucocutaneous lesions, fungemia, and sometimes focal infection of multiple sites. (msdmanuals.com)

Voriconazole was highly active against all the isolates. (who.int)
The isolates were identified by classical methods and the antifungal susceptibility tests were performed with the following drugs: amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole and caspofungin. (who.int)
Isolates with intermediate susceptibility to voriconazole and resistant to caspofungin were identified. (bvsalud.org)
Candida isolates detected by polymerase chain reaction restriction fragment length polymorphism were examined by standard antifungal disk diffusion susceptibility testing method for voriconazole, itraconazole, fluconazole, and ketoconazole. (ac.ir)
Furthermore, Candida isolates showed the highest sensitivity to voriconazole and ketoconazole and the lowest sensitivity to fluconazole. (ac.ir)
All Candida isolates were susceptible to fluconazole, voriconazole and amphotericin B. Overall, the level of antifungal resistance was low. (injectormedicaljournal.com)

Antifungal susceptibility profile of invasive Candida glabrata isolates (2009-2020) from a tertiary care hospital laboratory in Pakistan. (amedeo.com)
Yardimci AC, Arman D. Changing Trends of Candida Species and Antifungal Susceptibility Profile of Candida Bloodstream Isolates: A 5-Year Retrospective Survey. (injectormedicaljournal.com)
Anti-fungal susceptibility profile of Candida spp isolates by the microdilution method. (bvsalud.org)

The Candida fungus is both normal flora and an invasive pathogen. (medscape.com)
Candida glabrata is a successful pathogen colonising epithelial surfaces (mouth, gastrointestinal tract, vagina, skin, and present in stool) as healthy microbial flora with no age specificity [ 10 ] . (encyclopedia.pub)
Surprisingly, it has been reported that engulfed C. glabrata are able to survive in this harsh microenvironment, further suggesting alternative carbon metabolism as a potential strategy for this opportunistic fungal pathogen to persist in the host. (biomedcentral.com)
In this study, we attempted to validate a MALDI-ToF mass spectrometry-based assay for the antifungal susceptibility testing (AFST) of the potentially multidrug-resistant pathogen Candida glabrata against anidulafungin and fluconazole. (researchwithrutgers.com)
The type of antifungal drug employed must be selected based on the particular pathogen that is isolated or that is clinically suspected. (medscape.com)
8-10 Candida has been identified in high concentrations in the stools of malnourished children, frequently with associated diarrhoea, 11 , 12 and it has been reported as the sole "pathogen" in the stools of children with diarrhoea. (bmj.com)

Among 1,158 isolates col- and fluconazole-susceptible dose-dependent (F-SDD) lected during multicenter studies in South Korea during isolates ( 7 , 13 , 14 ), which can impede determination of 2008-2018, 5.7% were FR. (cdc.gov)
All isolates tested (n=53) were susceptible to AMB and VOR. (bmj.com)
Seven (24%) C glabrata strains were susceptible to FLU with 21 (72%) testing susceptible-dose dependent. (bmj.com)
The species isolated are less susceptible to FLU than most C albicans . (bmj.com)
We then sequenced CgPDR1 from each susceptible and resistant isolate and found two alleles with novel gain-of-function mutations. (uthsc.edu)
A third isolate, and its susceptible parent, harbored a CgPDR1 allele with a frameshift mutation which presumably results in a truncated CgPdr1p. (uthsc.edu)
All isolates were susceptible to amphotericin B. With the newcutoffpoints,important variations were observed in the isolates susceptibility profiles,particularly inC. glabrata,supportingtheneedof species identification,permanentsurveillance ofthe isolatesresistancetoanti-fungalsand correlationof the sensitivityresultswith theclinicalresponseto treatment. (bvsalud.org)
N. glabrata is less susceptible to fluconazole than other species. (msdmanuals.com)

Susceptibility of the isolates to antifungal agents was determined using the reference broth microdilution method. (who.int)

In one study, non- albicans Candida accounted for 70% of candidemia cases in a northern Indian pediatric ICU. (medscape.com)
The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. (centralparkcarriagesofficial.org)
Candidemia is a bloodstream infection arising from Candida species that is difficult to diagnose and treatment. (injectormedicaljournal.com)
The purpose of this study was to analyze the Candida species distribution, antifungal susceptibility, and mortality rate of isolates from candidemia patients in a tertiary city hospital. (injectormedicaljournal.com)

Opportunistic fungal organisms (eg, Candida species, Aspergillus species, Mucor species) tend to cause pneumonia in patients with congenital or acquired defects in the host immune defenses. (medscape.com)
[ 4 ] When the local ecology is disturbed, or where there is an immune defect, Candida overgrowth may lead to an opportunistic infection. (medscape.com)
[ 2 ] Candida is an opportunistic infection and typically occurs where the local ecology is disturbed, or where there is an immune defect. (medscape.com)

Prevalence of human pathogens of the clade Nakaseomyces in a culture collection-the first report on Candida bracarensis in Poland. (krakow.pl)

ABSTRACT This study was carried out from October 2003 to March 2007 to investigate susceptibility patterns to antifungals of Candida strains isolated from 410 immunocompromised patients in Shiraz, Islamic Republic of Iran. (who.int)
Genotypic analysis by 27A DNA fingerprinting of Candida albicans strains isolated during an outbreak in a neonatal intensive care unit. (microbiologyresearch.org)
strains isolated from OGC patients exhibited better adherence to BEC ( p = 0.05) than did the control group. (biomedcentral.com)

Echinocandins (caspofungin, micafungin, and anidulafungin) inhibit the β-1,3-glucan-synthase in Candida species. (dovepress.com)

The dearth of available antifungals and rapid increase in AMR in Candida pathogens emphasises the need for the development of new, more effective anticandida drugs and drug combinatorial treatments. (qub.ac.uk)
Candida glabrata is increasingly essential, due to rising isolation frequency and resistance development to antifungals. (upm.edu.my)
Contributing to this problem, C. glabrata exhibits intrinsic reduced susceptibility to the azole antifungals, and the development of high-level azole resistance during therapy has been reported in oral as well as bloodstream C. glabrata isolates in immunocompromised patients. (uthsc.edu)
The azole antifungals are fungistatic against Candida species, thus C. glabrata also exhibits tolerance to the azoles which may contribute to both therapeutic failures and ultimately the development of high-level azole resistance. (uthsc.edu)

For 64 patients with FR whether specific Pdr1p AAS result in fluconazole re- bloodstream infection isolates, the 30-day mortality rate sistance. (cdc.gov)
The range of infection with Candida species varies from a benign local mucosal membrane infection to disseminated disease. (medscape.com)
Episodes of candida infection at a teaching hospital were investigated. (microbiologyresearch.org)
The infection thrives best in the presence of Candida species-specific virulence factors such as the presence of hyphae for invasion into host tissues [ 19 ] . (encyclopedia.pub)
Infection is caused by Candida species, primarily Candida albicans . (medscape.com)
[ 10 ] In patients with HIV infection, new species, such as Candida dubliniensis and Candida inconspicua , have been recognized. (medscape.com)

This study aimed to determine the susceptibility of antifungal drugs against Candida species isolated from VVC in Northeastern Iran. (ac.ir)

Although the genus Candida consists of around 200 species, only 20 are reported as etiological agents of IC, being Candida albicans the most frequent causal agent. (intechopen.com)
and distinguish the different species of the Candida genus from patients with denture stomatitis (DS) and denture wearers without DS (control group). (bvsalud.org)

Candida albicans is a dimorphic fungus that is part of the commensal microbiota of the oral cavity. (biomedcentral.com)

With the new cutoff,the number of resistant isolates increased to seven (14%), of which two were SDD basedon the old criteria. (bvsalud.org)

Obtuve en 2019 la Acreditación en Investigación Avanzada por la AQU. (unav.edu)

We investigated the spectrum of yeasts isolated, and compared the epidemiological and laboratory characteristics of women carrying vulvovaginal Candida albicans with those carrying yeasts other than C albicans . (bmj.com)

The objective of this study was to determine the minimum inhibitory concentration (MIC) of fluconazole and amphotericin B in Candida isolates in clinically significant samples from hospitalized patients in Paraguay from May 2010 to August 2011 using the old and new criteria for fluconazole. (bvsalud.org)

AIMS To determine the prevalence of faecal candida in childhood diarrhoea and the relation between faecal yeasts and diarrhoea. (bmj.com)

The data show the potential of our assay for rapid detection of antifungal resistance, although the MS-AFST assay performed at 3 h of the in vitro antifungal exposure failed to detect C. glabrata isolates with echinocandin resistance-associated FKS2 mutations. (researchwithrutgers.com)
The yeasts were identified by MALDI-TOF mass spectrometry (MS). For all isolates, we performed phospholipases and proteinases assays, in vitro adherence to buccal epithelial cells (BEC), minimum inhibitory concentration of antifungal drugs and determined the cytokine profile by Cytometric Bead Array flow citometry assay. (biomedcentral.com)

C. albicans has been isolated from various sources (3,20), and is considered to be the most pathogenic species and frequently isolated from oral diseases in immunocompromised individuals (13). (scielo.br)

Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. (injectormedicaljournal.com)

The project will combine classical microbiology and molecular biology methods including culture isolation and characterisation of Category 2 fungal pathogens, drug susceptibility testing, cytotoxicity testing, phenotypic AMR characterisation of candida strains, nucleic acid extraction, PCR and qPCR, biochemical mechanism of action studies as well computational methods involving next generation sequencing and analysis and use of bioinformatics tools. (qub.ac.uk)
For intracellular human fungal pathogens such as Candida glabrata , an effective metabolic adaptation strategy is often required for survival and pathogenesis. (biomedcentral.com)
These studies have identified candida, but not other enteric pathogens, in the stools of patients with diarrhoea and have reported symptom resolution following treatment. (bmj.com)

Materials and Methods Candida albicans biofilms on acrylic resin plates were treated for 15 minutes with either nystatin, fluconazole, Polident, 220µM erythrosine + 1% (w/w) nano-TiO 2 + 15 J/cm 2 blue light photodynamic therapy (Ery PDT), or distilled water. (thieme-connect.de)

RÉSUMÉ La présente étude, réalisée entre octobre 2003 et mars 2007, a recherché les évolutions de la sensibilité aux antifongiques des souches de Candida isolées chez 410 patients immunodéprimés dans la ville de Chiraz (République islamique d'Iran). (who.int)
Des analyses régulières de la résistance aux antifongiques dans les centres médicaux sont fortement recommandées, car les résultats permettront une prise en charge plus efficace de la candidose systémique chez les patients immunodéprimés. (who.int)
infungihavebeenusedinthedevelop- clinicalsamples(blood,urine,oesopha- these recommended end-points for mentofcurrentlyavailableantifungal geal,oropharyngeal,vagina,biopsyand azolesarethelowestdrugconcentra- agents[1].Resistanceamong Candida broncho-alveolarlavage)wereexam- tionwithaprominentdecreaseintur- spp.toantifungaldrugsisanincreas- inedforfungalinfectionusingroutine bidity(inhibitoryconcentrationthat ingprobleminimmunocompromised methods.The Candida speciesisolated gives50%growthreduction),whilefor patients[2]. (who.int)
On occasion, isolates were found to be closely related within individual patients. (microbiologyresearch.org)
Candida species also pose a significant threat to patients in the intensive care unit (ICU) with consequential mortality outcomes. (encyclopedia.pub)
Observational studies indicate that diabetic patients with C. glabrata VVC respond poorly to azole drugs. (ias.ac.in)
The primary efficacy outcome was the mycological cure in patients with C. glabrata VVC in the two treatment arms. (ias.ac.in)
This study aimed to identify Candida species in the oral mucosa of 59 patients with orogastric cancer (OGC) and to analyze the immunological phenotype of these patients. (biomedcentral.com)
Candida glabrata is an emerging cause of oropharyngeal candidosis in patients receiving radiation around the head and neck. (medscape.com)

Although the proportion of non- albicans Candida species increased significantly, C. albicans is still the most frequently isolated Candida species from normally sterile body sites. (dovepress.com)
BACKGROUND Candida species are frequently isolated from stools of children with diarrhoea but are not proven enteropathogens. (bmj.com)

However, there is some incidence for antifungal resistance among some Candida strains, limiting treatment options. (intechopen.com)
Increasing incidence of C. glabrata among Candida species as a cause of BSI in U.S. ICUs between 1989 and 1999 in a survey showed that C. glabrata ranked second to C. albicans accounting for 20% to 24% of all Candida BSIs [ 12 ] . (encyclopedia.pub)

Candida species, such as Candida albicans and Candida glabrata, are ubiquitous and are considered benign residential microflora in the human body. (biomedcentral.com)

The C. glabrata complex was the predominant species among the NAC. (injectormedicaljournal.com)

Increasing isolation frequency of C. glabrata is associated with old age, as reported by Zhang et al. (encyclopedia.pub)

Of all the genes identified in the gene expression profiles for these four matched pairs, there were nine genes that were commonly upregulated with CgCDR1 in all four isolate sets ( YOR1 , LCB5 , RTA1 , YIM1 , YIL077c , POG1 , HFD1 , GLK1 , and FMS1 ). (uthsc.edu)

The sequences from selected 56 isolates were divided into seven groups (I-VII) on the basis of mutations in gyrA (S83L), parC (S80L, S80W and S84K) and gyrB (containing the novel mutations E679D, D644Y and A677V). (ophrp.org)

Anatomy3

Organisms11

Diseases10

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Phenomena and Processes13

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Tropicalis12

Parapsilosis5

Clinical19

Infections33

Krusei3

Yeast15

Fungi1

Candidiasis13

Voriconazole6

Susceptibility profile3

Pathogen6

Susceptible8

Microdilution method1

Candidemia4

Opportunistic3

Nakaseomyces1

Strains isolated3

Anidulafungin1

Antifungals4

Infection6

Species isolated1

Genus2

Fungus1

Resistant isolates1

20191

Vulvovaginal1

Amphotericin1

Prevalence1

Vitro2

Pathogenic1

Biofilm1

Pathogens3

Biofilms1

Patients9

Frequently isolated2

Incidence2

Ubiquitous1

Predominant species1

Isolation1

Commonly1

Mutations1