• The parent isoindole is a rarely encountered in the technical literature, but substituted derivatives are useful commercially and occur naturally. (wikipedia.org)
  • Unlike indole, isoindoles exhibit noticeable alternation in the C-C bond lengths, which is consistent with their description as pyrrole derivatives fused to a butadiene. (wikipedia.org)
  • A process for the preparation of isoindole derivatives which comprises heating a compound of the formula ##STR1## wherein R,R.sub.1,R.sub.2,R.sub.3,R.sub.4 and R.sub.5 are hereinafter set forth, in the presence of a suitable imidazole, is described. (patentgenius.com)
  • The isoindole derivatives prepared according to the process of the invention are characterized by the formula ##STR5## wherein R is lower alkyl and R.sub.1, R.sub.2, R.sub.3 and R.sub.4, independently, are hydrogen, halogen, lower alkyl, loweralkoxy or trifluoromethyl. (patentgenius.com)
  • Particularly preferred isoindole derivatives prepared in accordance with the process of the invention are 5-chloro-3-phenylisoindole-1-carboxylic acid ethyl ester and 5-chloro-3-(p-chlorophenyl)isoindole-1-carboxylic acid ethyl ester. (patentgenius.com)
  • In this study, we present a computational strategy, based on density functional theory, to calculate redox potentials and acid dissociation constants for a series of 16 isoindole-4,7-dione (IID) derivatives. (diva-portal.org)
  • A simple method was developed to prepare pyrimido[2,1-a]isoindole derivatives by using di-endo- and di-exo-ethyl 3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate enantiomers as chiral sources. (mta.hu)
  • In the case of enantiomeric starting substances, the chirality is transferred from norbornene derivatives to pyrimido[2,1-a]isoindoles. (mta.hu)
  • SUBSTANCE: invention relates to derivatives of 1,3-diiminoisoindoline, and more specifically to N 1 ,N 3 -bis(5-amino-3-pentyl-1,3,4-thiadiazol-2-ylidene)-2H-isoindole-1,3-diamine. (russianpatents.com)
  • The commercially important phthalimide is an isoindole-1,3-dione with two carbonyl groups attached to the heterocyclic ring. (wikipedia.org)
  • Stevens, Christian V. "Synthesis of isoindoles and related iso-condensed heteroaromatic pyrroles" Chemical Society Reviews 2012, volume 41, pp. 5626-5640. (wikipedia.org)
  • Kim, B, Yalaz, C & Pan, D 2012, ' Synthesis and characterization of membrane stable bis(arylimino)isoindole dyes and their potential application in nano-biotechnology ', Tetrahedron Letters , vol. 53, no. 32, pp. 4134-4137. (illinois.edu)
  • Three of the considered IIDs (5,6-dicyano-2-methyl-isoindole-4,7-dione, 5,6-dihydroxy-2-methyl-isoindole-4,7-dione, and 2-methyl-5-(trifluoromethyl)-isoindole-4,7-dione) are predicted to be particularly interesting for making polymers for organic cathodes because these are calculated to have high redox potentials and high specific capacities and to be readily polymerizable. (diva-portal.org)
  • 2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-Isoindole-1-carboxamide also known as NAV 26, is a potent and state-dependant blocker of sodium gated voltage channels with application towards pain relief. (trc-canada.com)
  • The invention relates to the chemical industry, namely the derivative of 1,3-diaminoethane, and specifically, N 1 N 3 bis(5-amino-3-pentyl-1,3,4-thiadiazole-2-ilidene)-2H-isoindole-1,3-diamine. (russianpatents.com)
  • 2.5 g of paraffin is placed in a porcelain Cup and heated to melt, pour in the molten solution of 0.015 g of N 1 N 3 bis(5-amino-3-pentyl-1,3,4-thiadiazole-2-ilidene)-2H-isoindole-1,3-diamine in 6 ml of DMF, stand when heated to remove DMF and the resulting mass is poured on a glass slide. (russianpatents.com)
  • Isoindole in heterocyclic chemistry is a benzo-fused pyrrole. (wikipedia.org)
  • Isoindoles units occur in phthalocyanines, an important family of dyes. (wikipedia.org)
  • 1,3-Bis(arylimino)isoindole dyes were synthesized and their properties to undergo intramolecular hydrogen bonding was studied with fluorescence spectroscopy in varying solvent polarities. (illinois.edu)
  • R. Bonnett and R. F. C. Brown "Isoindole" J. Chem. (wikipedia.org)
  • The products of this reaction, 1-alkyl-2-alkylthio-substituted isoindoles, exhibit optimal excitation at 330 nm and maximal emission at 465 nm. (environmental-expert.com)
  • The parent isoindole was prepared by flash vacuum pyrolysis of an N-substituted isoindoline. (wikipedia.org)
  • N-Substituted isoindoles do not engage is tautomerism and are therefore simpler to study. (wikipedia.org)