Cell Line, TumorTumor Suppressor Protein p53Cell LineMutationTumor Cells, CulturedApoptosisGene Expression Regulation, NeoplasticCell Line, TransformedMolecular Sequence DataBase SequencePhenotypeMutant ProteinsTransfectionRNA, MessengerBacterial ProteinsAmino Acid SequenceEscherichia coliGenetic Complementation TestCloning, MolecularTranscription, GeneticSignal TransductionBlotting, WesternGene DeletionPlasmidsGene ExpressionMutagenesis, Site-DirectedCell SurvivalCell DivisionKineticsDNA-Binding ProteinsPromoter Regions, GeneticReverse Transcriptase Polymerase Chain ReactionMice, Mutant StrainsCell ProliferationTranscription FactorsVirulenceCells, CulturedDNA PrimersProtein BindingCricetinaeAntineoplastic AgentsMembrane ProteinsMutagenesis, InsertionalGenes, BacterialMice, NudeGene Expression Regulation, BacterialPhosphorylationBinding SitesCarrier ProteinsPolymerase Chain ReactionCell DifferentiationTemperatureRecombinant Fusion ProteinsSequence Homology, Amino AcidDNAEpithelial CellsDrug ResistanceGene Expression ProfilingDrug Screening Assays, AntitumorNeoplasm ProteinsChromosome MappingFlow CytometryPoint MutationHeLa CellsAmino Acid SubstitutionSequence DeletionNuclear ProteinsTime FactorsCell Transformation, NeoplasticDown-RegulationDrug Resistance, NeoplasmDose-Response Relationship, DrugMice, Inbred BALB CGenetic VectorsCell CycleCulture MediaProtein Structure, TertiaryNeoplasm TransplantationFibroblastsCell MembraneBlotting, NorthernL Cells (Cell Line)Clone CellsBacterial AdhesionRNA, Small InterferingGene Expression RegulationDNA, ComplementaryCHO CellsAllelesDNA, BacterialProto-Oncogene ProteinsRecombination, GeneticAntibodies, MonoclonalGenesBreast NeoplasmsRestriction MappingColonic NeoplasmsBlotting, SouthernTrans-ActivatorsStructure-Activity Relationship