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  • enflurane
  • 2 demonstrated the deleterious effects of spillage of enflurane and isoflurane on polycarbonates present in the venous outlet of membrane oxygenators from cardiopulmonary bypass machines. (apsf.org)
  • In their laboratory tests, a few drops of enflurane and isoflurane that trickled onto the base of the venous reservoirs led to cracks within seconds of contact. (apsf.org)
  • surgical
  • If the results of a campuswide collaboration of University of Utah researchers are borne out by larger studies and trials, patients with refractory depression might one day have an alternative that is as effective as ECT but without the side effects - the surgical anesthetic drug isoflurane. (scienceblog.com)
  • oxidative
  • Isoflurane depolarized the mitochondrial membrane (−28%, n = 5), decreased oxidative phosphorylation (−59%, n = 5), and blunted the caffeine-induced Ca2+ transfer from SR to mitochondria (−22%, n = 7) in the cardiomyocytes of wild-type mice. (ovid.com)
  • myocardial
  • We also evaluated the relation between myocardial infarct size and coronary collateral blood flow in the presence and absence of isoflurane to determine if this relation is altered by the anesthetic agent. (asahq.org)
  • Therefore, the authors hypothesized that isoflurane, by inhibiting the respiratory chain complex I, another regulator of PTP, might reinforce the myocardial protection afforded by CypD inhibition. (ovid.com)
  • goats
  • Intravenous MDZ at 0.2 mg/kg administered to isoflurane-anaesthetised goats may result in transient apnoea and a mild decrease in V T and V T /kg. (scielo.org.za)
  • MeSH
  • Isoflurane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • partial
  • The results suggest that the partial inhibitory effect of isoflurane on respiratory complex I is insufficient to afford a synergy to CypD-induced protection. (ovid.com)
  • protects
  • Emulsified isoflurane protects isolated rat KCs against H/R induced injury by decreasing the production of ROS and TNF-α and attenuating apoptosis in KCs. (medsci.org)
  • depression
  • In a pilot study with 20 patients who received ECT treatments compared to eight patients who received the isoflurane treatments, the researchers found that both therapies provided significant reduction in symptoms of depression. (scienceblog.com)
  • In the mid-1980s, researchers in Europe studied isoflurane as a potential depression therapy. (scienceblog.com)
  • Researchers don't know what produces the relief of depression symptoms from ECT or isoflurane. (scienceblog.com)
  • This period of electrical rest for the brain may be a potential explanation for why ECT and isoflurane improve depression. (scienceblog.com)
  • mice
  • In 2008, members of the same MGH research team showed that isoflurane induced Alzheimer's-like changes - increasing activation of enzymes involved with cell death and generation of the A-beta plaques characteristic of the disease - in the brains of mice. (medindia.net)
  • results
  • Later studies by other scientists, however, failed to confirm the results of the original work and isoflurane research fell out of favor. (scienceblog.com)
  • group
  • Isoflurane was delivered by an agent-specific vaporiser (Isotec, MkIII, Scientific Group, Randburg, South Africa), with the fresh gas flow rate set at 30 mL/kg/min for the first 15 min and thereafter reduced to 10 mL/kg/min. (scielo.org.za)
  • 32 pentobarbital-anesthetized Sprague-Dawley rats were equally randomized into four groups: laparotomy group (Sham group), hepatic I/R and normal saline infusion group (I/R+S group), I/R and lipid vehicle infusion (I/R+V group), or I/R and 8% emulsified isoflurane infusion (I/R+E group) at the rate of 8 ml·kg -1 ·h -1 for 30 min. (medsci.org)
  • major
  • This graph shows the total number of publications written about "Isoflurane" by people in Harvard Catalyst Profiles by year, and whether "Isoflurane" was a major or minor topic of these publication. (harvard.edu)
  • level
  • Approximately 1 hour after the start of the procedure, the isoflurane fill level on the viewing glass was noted to be nearing empty, and the vaporizer was refilled. (apsf.org)