Islet Amyloid PolypeptideAmyloidIslets of LangerhansAmyloid beta-PeptidesSerum Amyloid A ProteinAmyloid beta-Protein PrecursorAmyloidosisPlaque, AmyloidIslets of Langerhans TransplantationReceptors, Islet Amyloid PolypeptideCongo RedCerebral Amyloid AngiopathySerum Amyloid P-ComponentInsulin-Secreting CellsAmyloid NeuropathiesAmyloid Precursor Protein SecretasesHemizygoteAlzheimer DiseaseSomatostatin-Secreting CellsGenes, polMice, TransgenicDiabetes Mellitus, Type 2InsulinGlucagonomaInsulinomaGlucagon-Secreting CellsAmyloid Neuropathies, FamilialMolecular Sequence DataPeptide FragmentsAmino Acid SequenceThiazolesProtein Structure, SecondaryMicroscopy, Electron, TransmissionProtein MultimerizationPrealbuminGlucagonSomatostatinPancreasGene Products, polPancreatic PolypeptidePropanolsLissamine Green DyesAspartic Acid EndopeptidasesPresenilin-1Protein FoldingGlucoseGlucose Transporter Type 2Disease Models, AnimalBrainMicroscopy, ElectronMicroscopy, Atomic ForceCircular DichroismCerebral Amyloid Angiopathy, FamilialMice, Inbred C57BLPeptidesPrionsProtein BindingDiabetes Mellitus, Type 1MutationDiabetes Mellitus, ExperimentalImmunohistochemistryProtein ConformationUnilamellar LiposomesModels, MolecularBlood GlucoseAmyloidosis, FamilialTissue Culture TechniquesPancreatic DiseasesNeprilysinProtein Structure, QuaternaryNeurofibrillary TanglesGlucose Tolerance TestKineticsCell LineTime FactorsGene Expression RegulationProtein PrecursorsRecombinant ProteinsSpectrophotometry, InfraredBase SequenceHyperglycemiaAgingRNA, Messengertau ProteinsHydrophobic and Hydrophilic InteractionsApoptosisMolecular Dynamics SimulationMicroscopy, ImmunoelectronProtease NexinsCell SurvivalAniline Compoundsbeta 2-MicroglobulinPancreatic NeoplasmsProtein Processing, Post-TranslationalBody WeightLipid BilayersHeparitin SulfateCells, CulturedEndopeptidasesNeurons