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  • reduces
  • Conclusion Remote ischaemic preconditioning using lower limb ischaemia reduces myocardial infarct size by activating the PI3K-Akt component of the RISK pathway. (bmj.com)
  • severe
  • Similar to cerebral hypoxia, severe or prolonged brain ischemia will result in unconsciousness, brain damage or death, mediated by the ischemic cascade. (wikipedia.org)
  • The latter two conditions are jointly referred to as tissue loss, reflecting the development of surface damage to the limb tissue due to the most severe stage of ischemia. (wikipedia.org)
  • As of April 2017, the Best Endovascular Versus Best Surgical Therapy for Patients with Critical Limb Ischemia (BEST-CLI) has enrolled nearly half of the 2100 patients needed to complete the trial.A similar study, BASIL 2 (Bypass Versus Angio plasty in Severe Ischaemia of the Leg), is being conducted in the United Kingdom. (wikipedia.org)
  • Bypass Versus Angio plasty in Severe Ischaemia of the Leg - 2 (BASIL-2) trial: study protocol for a randomised controlled trial. (wikipedia.org)
  • Venous thrombosis leads to congestion of the affected part of the body, while arterial thrombosis (and rarely severe venous thrombosis) affects the blood supply and leads to damage of the tissue supplied by that artery (ischemia and necrosis). (wikipedia.org)
  • induce
  • In some cases, rapid weight loss for other reasons can induce mesenteric ischemia if a patient is already prone to the condition. (everything2.com)
  • Retinal ischemia may induce new vessel growth on the iris surface, shown by the arrow. (aao.org)
  • By design, these devices induce ischemia to the lower extremities (as a secondary effect, or less commonly as their primary use). (wikipedia.org)
  • diagnosis
  • If there is a suspicion that one may have coronary ischemia, a doctor will administer a series of tests to confirm the diagnosis. (wikipedia.org)
  • vascular disease
  • Reduced blood flow to the skin layers may result in mottling or uneven, patchy discoloration of the skin Ischemia is a vascular disease involving an interruption in the arterial blood supply to a tissue, organ, or extremity that, if untreated, can lead to tissue death. (wikipedia.org)
  • coronary
  • Coronary ischemia is linked to heart disease as well as heart attacks. (wikipedia.org)
  • Chest pain is a major indication of coronary ischemia. (wikipedia.org)
  • Chest pain radiating down the left arm is also a symptom of coronary ischemia and the pain can also be radiating directly to the back in some instances. (wikipedia.org)
  • Women and those who are young may show abnormalities on their test even though no signs of coronary ischemia or CAD are present. (wikipedia.org)
  • A coronary angiography is performed only after a stress test or ECG shows a sign of coronary ischemia or CAD. (wikipedia.org)
  • Coronary ischemia has some serious side effects if it is not treated. (wikipedia.org)
  • tissue damage
  • Ischemia" implies a tissue damage derived from perfusion insufficiency, not just an inadequate blood supply. (springer.com)
  • Unconsciousness, such as due to the ingestion of excessive doses of central depressants like alcohol or opioids, can result in ischemia of the extremities due to unusual body positions that prevent normal circulation Ischemia results in tissue damage in a process known as ischemic cascade. (wikipedia.org)
  • patients
  • The cells are planned to be injected into the legs of critical limb ischemia patients where they are expected to migrate to oxygen-low areas in the patient's diseased limbs. (ucdavis.edu)
  • In a series of 58 patients with mesenteric ischemia due to mixed causes: White blood cell count >10.5 in 98% (probably an overestimate as only tested in 81% of patients) Lactic acid elevated 91% (probably an overestimate as only tested in 57% of patients) A number of devices have been used to assess the sufficiency of oxygen delivery to the colon. (wikipedia.org)
  • Design and Rationale of the Best Endovascular Versus Best Surgical Therapy for Patients With Critical Limb Ischemia (BEST-CLI) Trial. (wikipedia.org)
  • detection
  • Techniques for detection and treatment of myocardial ischemia are described that monitor both the electrical and dynamic mechanical activity of the heart to detect and verify the occurrence of myocardial ischemia in a more reliable manner. (google.com.au)
  • The techniques correlate contractility changes detected by an accelerometer or pressure sensor with changes in the ST electrogram segment detected by the electrodes to increase the reliability of ischemia detection. (google.com.au)
  • The main fields of use are the risk stratification of ventricular tachycardia (VT) and the detection of stress induced ischemia. (wikipedia.org)
  • brains
  • In 1974, Hossmann and Zimmermann demonstrated that ischemia induced in mammalian brains for up to an hour can be at least partially recovered. (wikipedia.org)