Ischaemia. Medical search. Frequent questions

In addition to limb ischaemia, other organs can become ischaemic, causing: Renal ischemia (nephric ischaemia) Mesenteric ischaemia Cerebral ischaemia Cardiac ischaemia Once signs and symptoms of acute limb ischemia are identified, the cause and location of the occlusion and its severity need to be addressed. (wikipedia.org)
Mesenteric artery ischemia occurs when there is a narrowing or blockage of one or more of the three major arteries that supply the small and large intestines. (medlineplus.gov)
The outlook for chronic mesenteric ischemia is good after a successful surgery. (medlineplus.gov)
People with acute mesenteric ischemia often do poorly because parts of the intestine may die before surgery can be done. (medlineplus.gov)
However, with prompt diagnosis and treatment, acute mesenteric ischemia can be treated successfully. (medlineplus.gov)
Tissue death from lack of blood flow (infarction) in the intestines is the most serious complication of mesenteric artery ischemia. (medlineplus.gov)
Chronic mesenteric ischemia (CMI) usually results from long-standing atherosclerotic disease of two or more mesenteric vessels. (medscape.com)
In 1958, Shaw and Maynard described the first thromboendarterectomy of the superior mesenteric artery (SMA) for the treatment of both acute mesenteric ischemia (AMI) and CMI. (medscape.com)
Mastery of the anatomy of the mesenteric vessels is essential to management of chronic mesenteric ischemia (CMI), although the wide array of vascular variations can make such mastery difficult to achieve. (medscape.com)
This communication is an important connection that helps maintain bowel perfusion in the setting of mesenteric ischemia. (medscape.com)
Chronic mesenteric ischemia, also known as intestinal angina, is defined by reduced blood flow to major mesenteric arteries (celiac, superior mesenteric, inferior mesenteric) causing abdominal pain which is often postprandial. (logicalimages.com)
Chronic mesenteric ischemia is typically caused by atherosclerotic disease. (logicalimages.com)
The same risk factors for peripheral and coronary artery disease predispose to chronic mesenteric ischemia, namely smoking, hypertension, diabetes, and hyperlipidemia. (logicalimages.com)
In the first part of my talk, I discussed colon ischemia and now in the second part of my talk, I'm going to discuss a variety of topics including acute mesenteric ischemia, focal segmental ischemia, mesenteric arterial occlusive disease, mesenteric venous thrombosis, and chronic mesenteric ischemia or intestinal angina. (hstalks.com)
I'm now going to talk about acute mesenteric ischemia, which also is a spectrum of disease. (hstalks.com)
Next most common is non-exclusive mesenteric ischemia. (hstalks.com)
The blood vessels were relatively normal and it was, therefore, called non-inclusive mesenteric ischemia. (hstalks.com)
Superior mesenteric venous thrombosis accounts for 5 - 10 percent of patients with acute mesenteric ischemia and focal segmental ischemia, probably another 5 percent. (hstalks.com)
Acute mesenteric ischemia is sudden blockage of blood flow to part of the intestines, which may lead to gangrene and perforation (puncture). (msdmanuals.com)
Acute mesenteric ischemia has multiple causes. (msdmanuals.com)
If the person has typical symptoms of acute mesenteric ischemia or if the abdomen is very tender, doctors usually take the person right to surgery. (msdmanuals.com)

Acute limb ischaemia (ALI) occurs when there is a sudden lack of blood flow to a limb, within 14 days of symptoms onset. (wikipedia.org)
Acute limb ischaemia is caused by embolism or thrombosis, or rarely by dissection or trauma. (wikipedia.org)
Acute limb ischaemia can occur in patients through all age groups. (wikipedia.org)
People who smoke tobacco cigarettes and have diabetes mellitus are at a higher risk of developing acute limb ischaemia. (wikipedia.org)
When a limb is ischaemic in the non-acute (chronic) setting, the condition is alternatively called peripheral artery disease or critical limb ischaemia, rather than ALI. (wikipedia.org)
In treating acute limb ischaemia time is everything. (wikipedia.org)
In the worst cases, acute limb ischaemia progresses to critical limb ischaemia, and results in death or limb loss. (wikipedia.org)
Compartment syndrome can occur because of acute limb ischaemia because of the biotoxins that accumulate distal to the occlusion resulting in edema. (wikipedia.org)
citation needed] The primary intervention in acute limb ischaemia is emergency embolectomy using a Fogarty Catheter, providing the limb is still viable within the 4-6h timeframe. (wikipedia.org)
Professor Bradbury led the HTA-funded Bypass Versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial, which was the first, and only, randomised controlled trial to investigate whether surgical bypass or keyhole treatment is best at relieving symptoms and preventing amputation or death in patients with Severe Limb Ischaemia (SLI). (birmingham.ac.uk)
All patients who underwent revascularisation in Sweden between May 2008 and May 2013 for intermittent claudication (IC) or critical limb ischaemia (CLI), aged 50 years and older, were identified through the Swedvasc database. (lu.se)
A 10-year experience of managing acute limb ischaemia in India. (who.int)
Acute limb ischaemia is threatening to both limb and life. (who.int)
We did a retrospective analysis of the clinical profile of patients presenting with non-traumatic acute limb ischaemia to our department (a tertiary care centre in India) from January 1998 to December 2007. (who.int)
Acute limb ischaemia is a catastrophic event. (who.int)

Magnetic resonance imaging (MRI) and histological studies in rat focal ischemia models using transient middle cerebral artery (MCA) occlusion indicate that reperfusion after an ischemic episode of 2- to 3-hour duration does not result in reduction of the size of the infarct. (nih.gov)
Ren C, Yan Z, Wei D et al (2009) Limb remote ischemic postconditioning protects against focal ischemia in rats. (springer.com)

These issues are "not very controversial" among cardiac electrophysiologists, Hussein said, but it remains "common practice" for other specialists to order angiography or ischemia testing for patients with monomorphic VT storm, typically in the cardiac care unit (CCU), before considering ablation. (medscape.com)
Myocardial ischemia, also called cardiac ischemia, reduces the heart muscle's ability to pump blood. (sparrow.org)
Ischemia and reperfusion can cause serious brain damage in stroke or cardiac arrest. (benbest.com)
The main objective of this work is to improve understanding of the regulation of energy metabolism during skeletal/cardiac muscle ischemia by combining in vivo experiments and quantitative models of metabolism. (nasa.gov)
Surprisingly, Txnip-KO hearts had greater recovery of cardiac function after an ischemia-reperfusion insult. (jci.org)
Progenitor cell therapy is being investigated for the treatment of damaged myocardium resulting from acute or chronic cardiac ischemia and for refractory angina. (southcarolinablues.com)
For individuals who have acute cardiac ischemia who receive progenitor cell therapy, the evidence includes 2 randomized controlled trials (RCTs) with 200 patients, numerous small RCTs, and meta-analyses of these RCTs. (southcarolinablues.com)
For individuals who have chronic cardiac ischemia who receive progenitor cell therapy, the evidence includes a nonrandomized comparative trial and systematic reviews of smaller RCTs. (southcarolinablues.com)
The patient had severe cardiac dysfunction and atrial fibrillation and presented with acute ischemia in the right lower limb 24 h after receiving an inferior vena cava filter. (medscape.com)

Transient forebrain ischemia leads to delayed death of the CA1 neurons in the hippocampus. (nih.gov)
Immunohistochemical and biochemical investigations of Ca2+/calmodulin-dependent protein kinase II(CaM kinase II) and protein phosphatase (calcineurin) after transient forebrain ischemia demonstrated that the activity of CaM kinase II was decreased in the CA1 region of the hippocampus early (6-12 hours) after ischemia. (nih.gov)
Bowel ischemia represents a process of insufficient blood supply of the small or large bowel with the consequences ranging from a transient, totally reversible attack to a lethally catastrophic event. (ajronline.org)
Induction of transient chemical ischemia resulted in unexpectedly large Na + influx, accompanied by considerable cell swelling. (jneurosci.org)
Liang HW, Qiu SF, Shen J et al (2008) Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus. (springer.com)
Jeong S, Kim SJ, Jeong C et al (2012) Neuroprotective effects of remifentanil against transient focal cerebral ischemia in rats. (springer.com)
IPC is described as short, transient, and nonlethal ischemia periods and subsequent reperfusion which is performed before IR injury and can protect the kidney against long-term ischemia [ 6 - 8 ]. (hindawi.com)

Studies have shown that puerarin reduced cerebral edema in rats with cerebral ischemia-reperfusion injury, removed lipid peroxidation products, enhanced antioxidant capacity, improved antioxidant activity of the brain tissue, and reduced the degree of focal cerebral ischemic injury [ 2 - 4 ]. (hindawi.com)
To evaluate the effects of dexmedetomidine on myocardial ischemia-reperfusion injury in rats and its anti-apoptotic role, as well as the mechanism by which it regulates Janus kinase 2/signal transducers and activators of transcription 3 signal. (ijpsonline.com)
Dexmedetomidine pretreatment can obviously relieve myocardial ischemia-reperfusion injury and cardiomyocyte apoptosis in rats probably by activating the Janus kinase 2/signal transducers and activators of transcription 3 signaling pathway. (ijpsonline.com)
Here we investigated whether remifentanil postconditioning exerts neuroprotective effects against global cerebral ischemia/reperfusion injury in rats and its potential mechanisms. (springer.com)
The results suggest that remifentanil postconditioning exhibits neuroprotective effects against global cerebral ischemia/reperfusion injury in rats, and its mechanisms might involve inhibition of neuronal apoptosis through the PI3K pathway. (springer.com)
Wang JY, Shen J, Gao Q et al (2008) Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats. (springer.com)
Ding ZM, Wu B, Zhang WQ et al (2012) Neuroprotective Effects of Ischemic Preconditioning and Postconditioning on Global Brain Ischemia in Rats through the same effect on inhibition of apoptosis. (springer.com)
In two models of partial renal IR with and without ischemia preconditioning (IPC) and using Mas receptor (MasR) blockade, A779 or its vehicle, the renal vascular responses to angiotensin II (Ang II) administration in two-kidney-one-clip (2K1C) hypertensive rats were determined. (hindawi.com)
The rats in the IR group underwent 45 min partial kidney ischemia, and the animals in the IPC + IR group underwent two 5 min cycles of partial kidney ischemia followed by 10 min reperfusion and partial kidney ischemia for 45 min. (hindawi.com)
In the present work, a hypoxia/reoxygenation (H/R) model in NRK-52E cells and ischemia-reperfusion model in rats were used. (mdpi.com)

The left anterior descending coronary artery was ligated to construct the model of myocardial ischemia-reperfusion. (ijpsonline.com)
The effects of acidified sodium nitrite (NaNO2) which releases nitric oxide, a substance which is thought to be indistinguishable from endothelium-derived relaxing factor, were investigated in a 6-h model of myocardial ischemia (MI) with reperfusion in open-chest, anesthetized cats. (aspetjournals.org)

In this sense, ischaemia refers to the inhibition of blood flow to/through the limb. (wikipedia.org)
Meng X, Zhang L, Han B and Zhang Z: PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis. (spandidos-publications.com)

It is different from another condition which is more chronic (more than 14 days) called critical limb ischemia (CLD). (wikipedia.org)
While limbs in both acute and chronic limb ischemia may be pulseless, a chronically ischemic limb is typically warm and pink due to a well-developed collateral artery network and does not need emergency intervention to avoid limb loss. (wikipedia.org)
Exposure to air pollution, especially fine particulate matter, is a leading risk factor for noncommunicable diseases, in particular: ischaemia, myocardial infarction, stroke, chronic obstructive pulmonary disease and cancers. (who.int)

Patients with a severe form of ventricular arrhythmia who may be referred for catheter ablation are often first tested for coronary artery disease (CAD) or ischemia. (medscape.com)
The findings, they say, question such routine CAD/ischemia testing in patients like those studied, who had episodes of monomorphic ventricular tachycardia (VT) storm but not an acute coronary syndrome (ACS) and ultimately went to ablation. (medscape.com)
The findings "argue against performing routine evaluations to rule out coronary [disease] or myocardial ischemia as culprits in monomorphic VT storm" in patients without evidence of ACS, write Feras Alkhalaileh, MD, Heart and Vascular Institute, Cleveland Clinic, Ohio, and colleagues in their report published August 2 in JACC: Clinical Electrophysiology . (medscape.com)
Amsterdam, the Netherlands and New Orleans, U.S. - At the American College of Cardiology's (ACC) annual meeting in New Orleans, U.S., Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced the results of the DEFINE PCI [1] study, which assessed the level of residual ischemia found in patients after percutaneous coronary interventions (PCI). (philips.com)
PCI is an image-guided, minimally invasive treatment to open a coronary artery blockage (stenosis) that is causing a reduced blood flow (ischemia) to heart tissue. (philips.com)
The objective of the study was to identify the parameter(s) of cardiopulmonary exercise testing (CPET) that can detect exercise-induced myocardial ischaemia (EIMI), and to determine its diagnostic accuracy for identifying patients with coronary artery disease (CAD). (nih.gov)
Myocardial ischemia occurs when the blood flow through one or more of your coronary arteries is decreased. (sparrow.org)
Coronary artery spasm is an uncommon cause of myocardial ischemia. (sparrow.org)
A study published on July 9 in the Journal of the American College of Cardiology: Cardiovascular Imaging found that "in stable coronary artery disease (CAD), ischemia worsening is an independent predictor of death or myocardial infarction (MI), resulting in significantly improved risk reclassification when added to previously known predictors. (acc.org)
Looking at "1,425 consecutive patients with angiographically documented CAD who underwent two serial MPS scans," ischemia change was calculated for patients undergoing medical therapy (MT) alone, percutaneous coronary intervention (PCI), or coronary artery bypass grafting (CABG). (acc.org)
Ischaemia reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia, and is a common complication in interventional procedures for acute myocardial infarction and coronary bypass surgery. (pharmaceutical-technology.com)
Diabetes is a pivotal cause of asymptomatic myocardial ischemia (MI) even in the absence of coronary artery disease [ 3 ]. (springer.com)

and global ischemia, which encompasses wide areas of brain tissue. (wikipedia.org)
Charron C, Messier C, Plamondon H (2008) Neuroprotection and functional recovery conferred by administration of kappa- and delta 1-opioid agonists in a rat model of global ischemia. (springer.com)

Revascularization for silent ischemia was associated with better outcomes in the long run compared with medical therapy alone, a registry study suggested. (medpagetoday.com)
Practice varied substantially among hospitals: their ratios of revascularization vs medical therapy for silent ischemia ranged from under 0.80 to more than 1.60 (average 1.12). (medpagetoday.com)
He pointed to the ISCHEMIA trial that includes patients with silent ischemia and is to be presented in 2019. (medpagetoday.com)
Some people who have myocardial ischemia don't have any signs or symptoms (silent ischemia). (sparrow.org)

Sun W, Wang Z, Sun M, Huang W and Wang Y and Wang Y: Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway. (spandidos-publications.com)

Renal ischemia-reperfusion injury (IRI) is considered as a major cause of acute kidney injury. (frontiersin.org)
Renal ischemia-reperfusion injury (IRI) is a common pathophysiological phenomenon in clinical settings. (frontiersin.org)
Kidney partial ischemia-reperfusion (IR) injury is defined as a reduction of the renal blood flow (RBF) followed by the recovery of RBF and reoxygenation [ 1 ]. (hindawi.com)
Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). (mdpi.com)

Other effects that may result from brain ischemia are stroke, cardiorespiratory arrest, and irreversible brain damage. (wikipedia.org)
citation needed] Other pathological events that may result in brain ischemia include cardiorespiratory arrest, stroke, and severe irreversible brain damage. (wikipedia.org)
Cannabinoids may have therapeutic potential in disorders resulting from cerebral ischemia, including stroke, and may protect neurons from injury through a variety of mechanisms. (erowid.org)
Migraine is likely to increase individual vulnerability to ischemic stroke during the process of acute brain ischemia and might represent, therefore, a potential new therapeutic target against occurrence and progression of the ischemic damage. (medscape.com)
[ 1 ] A recent hypothesis to explain the migraine-stroke association, based on experimental data obtained in mice expressing familial hemiplegic migraine type 1 mutations, is that the cerebral hyperexcitability phenotype associated with migraine might sensitize brain tissue to ischemia. (medscape.com)
Based on these premises, taking advantage of the reliability of computed tomography perfusion (CTP) imaging in the estimation of cerebral tissue viability in both clinical and research settings, [ 4 ] we conducted a case-control study comparing CTP maps of migraineurs and nonmigraineurs patients with acute ischemic stroke aimed at investigating whether a personal history of migraine is associated with vulnerability to brain ischemia. (medscape.com)

QT dispersion and components of the QT interval in ischaemia and infarction. (bmj.com)
Prolonged ischemia may lead to INFARCTION of spinal cord tissue. (harvard.edu)
This Myocardial Ischaemia National Audit Project (MINAP) report covering 2018/19 data records approximately 87,000 cases of heart attack - either ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) - admitted to hospitals in England, Wales and Northern Ireland. (hqip.org.uk)
Stealth is currently initiating a multinational Phase II clinical study evaluating Bendavia as a treatment for ischemia reperfusion injury in patients experiencing acute ST-segment elevation myocardial infarction. (pharmaceutical-technology.com)
metabolic acidosis, arrhythmias, myocardial ischemia or infarction, and noncardiogenic pulmonary edema, although any organ system might be involved. (cdc.gov)

citation needed] Blockage of arteries due to plaque buildup may also result in ischemia. (wikipedia.org)

Myocardial ischemia occurs when blood flow to your heart is reduced, preventing the heart muscle from receiving enough oxygen. (sparrow.org)
Thus, enhanced alpha-adrenergic responsiveness occurs during myocardial ischemia and appears to be primary mediator of the electrophysiological derangements and resulting malignant dysrhythmias induced by catecholamines during myocardial ischemia and reperfusion. (jci.org)

A Doppler evaluation is used to show the extent and severity of the ischaemia by showing flow in smaller arteries. (wikipedia.org)
Ischemia within the arteries branching from the internal carotid artery may result in symptoms such as blindness in one eye, weakness in one arm or leg, or weakness in one entire side of the body. (wikipedia.org)
Ischemia within the arteries branching from the vertebral arteries in the back of the brain may result in symptoms such as dizziness, vertigo, double vision, or weakness on both sides of the body[citation needed]. (wikipedia.org)
Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population. (wikipedia.org)
citation needed] Compression of blood vessels may also lead to brain ischemia, by blocking the arteries that carry oxygen to the brain. (wikipedia.org)
Myocardial ischemia can develop slowly as arteries become blocked over time. (sparrow.org)

The microvascular and parenchymal organ damage induced upon ischemia tissue reperfusion is mainly attributed to the reactive oxygen-free radicals, and it has been demonstrated in many organs. (frontiersin.org)
Cerebral hyperexcitability in migraine experiencers might sensitize brain tissue to ischemia. (medscape.com)
Digital ischemia is associated with atherosclerotic, thromboembolic, or connective tissue diseases . (bvsalud.org)

Therefore, derivatives of puerarin may serve as promising approach to improve neuron function in ischemia-reperfusion brain injury-related disorders. (hindawi.com)

ROC analysis selected a two-variable model-O(2)pulse flattening duration, calculated from the onset of myocardial ischaemia to peak exercise, and deltaVO(2)/deltawork rate slope-to predict EIMI by CPET. (nih.gov)
Currently, we are investigating the difference in the responses to sudden vs. gradual onset ischemia in swine by combining in vivo experimental studies with computational models of myocardial energy metabolism during normal and ischemic conditions. (nasa.gov)

We hypothesized that an imbalance of Ca2+/calmodulin dependent protein phosphorylation-dephosphorylation may be involved in delayed neuronal death after ischemia. (nih.gov)
Global cerebral ischemia followed by reperfusion, which leads to extensive neuronal damage, particularly the neurons in the hippocampal CA1 region. (springer.com)
Apoptosis is one of the major mechanisms that lead to neuronal death after cerebral ischemia and reperfusion. (springer.com)
We found remifentanil postconditioning markedly improved the spatial learning and memory as well as attenuated neuronal apoptosis in hippocampus caused by cerebral ischemia/reperfusion injury. (springer.com)

However, whether GRh2 has a protective effect on ischaemia/reperfusion (I/R) in the myocardium has yet to be elucidated. (spandidos-publications.com)

The clot might block an artery and lead to sudden, severe myocardial ischemia, resulting in a heart attack. (sparrow.org)

Of 97 such patients, about 44% underwent CAD/ischemia testing by invasive angiography, myocardial functional imaging, or both. (medscape.com)
All patients underwent an incremental exercise stress testing (ECG-St) with breath-by-breath gas exchange analysis, followed by a 2-day stress/rest gated SPECT myocardial scintigraphy (GSMS) as the gold standard for ischaemia detection. (nih.gov)
All subjects underwent Technetium-99 m sestamibi single-photon emission computed tomographic imaging for the estimation of myocardial ischemia, expressed as Summed Stress Score (SSS). (springer.com)
He subsequently underwent a Roux-en-Y reconstruction and gastrostomy tube placement via the distal gastric remnant. (sages.org)

Global cerebral ischemia was performed via 10 min of four-vessel occlusion. (springer.com)

This article describes the pathophysiology of, and treatment strategy for, cerebral ischemia. (nih.gov)
Reperfusion plays an important role in the pathophysiology of cerebral ischemia. (nih.gov)

The development of effective neuroprotection methods and the establishment of reliable imaging modalities for an early and accurate diagnosis of the extent and degree of the ischemia are imperative. (nih.gov)

Brain ischemia is a condition in which there is insufficient bloodflow to the brain to meet metabolic demand. (wikipedia.org)
Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis. (wikipedia.org)
The main symptoms of brain ischemia involve impairments in vision, body movement, and speaking. (wikipedia.org)
The causes of brain ischemia vary from sickle cell anemia to congenital heart defects. (wikipedia.org)
Symptoms of brain ischemia can include unconsciousness, blindness, problems with coordination, and weakness in the body. (wikipedia.org)
Accordingly, this discovery raised the possibility of intervening after brain ischemia before the damage becomes irreversible. (wikipedia.org)
The symptoms of brain ischemia reflect the anatomical region undergoing blood and oxygen deprivation. (wikipedia.org)
The symptoms of brain ischemia range from mild to severe. (wikipedia.org)
Similar to cerebral hypoxia, severe or prolonged brain ischemia will result in unconsciousness, brain damage or death, mediated by the ischemic cascade. (wikipedia.org)
Brain ischemia has been linked to a variety of diseases or abnormalities. (wikipedia.org)
Sickle cell anemia may cause brain ischemia associated with the irregularly shaped blood cells. (wikipedia.org)
citation needed] A heart attack can also cause brain ischemia due to the correlation that exists between heart attack and low blood pressure. (wikipedia.org)
Therefore, brain ischemia can result from events other than heart attacks. (wikipedia.org)
citation needed] Congenital heart defects may also cause brain ischemia due to the lack of appropriate artery formation and connection. (wikipedia.org)
The original phenolic hydroxyl in the puerarin molecules was substituted in order to change the blood-brain barrier permeability and thus enhance the efficacy for preventing cerebral ischemia/reperfusion injury. (hindawi.com)
The results showed that puerarin derivative P1-EA and P2-EA were resulting in an increased lipophilicity that enabled the derivatives to pass more efficiently through the blood-brain barrier, thus, improving the protective effects against cerebral ischemia/reperfusion injury. (hindawi.com)
In addition, we tested the anticerebral ischemia-reperfusion injury activity of these puerarin derivatives in order to determine their permeability through the blood-brain barrier and pharmacological activity. (hindawi.com)
Yuan Y, Guo Q, Ye Z et al (2011) Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway. (springer.com)
In this study, we examined the histological presence of insulin-like growth factor-I (IGF-1) and insulin receptor substrate (IRS-1) in anatomically distinct brain circuits compared with morphological brain damage in a co-morbid rat model of striatal ischemia (ET1) and A beta toxicity. (bepress.com)
We investigated whether a personal history of migraine is associated with vulnerability to brain ischemia in humans. (medscape.com)

Retinal ischemia/reperfusion (I/R) injury can cause severe vision impairment. (mdpi.com)

Details for: Treatment of reversible myocardial ischemia-angina pectoris. (who.int)

As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in patients with type 2 diabetes mellitus and no history of cardiovascular events. (springer.com)
After 6 cycles, he remained asymptomatic and symptoms of digital ischemia were completely resolved. (bvsalud.org)

Of the patients with residual ischemia, the study showed that 81.6% of those patients had an untreated focal stenosis (narrowing of an artery). (philips.com)
The mouse model of cerebral artery ischemia/reperfusion injury was established to test the anticerebral ischemia-reperfusion injury activity of the puerarin derivatives. (hindawi.com)

citation needed] Large blood clots can also cause ischemia by blocking blood flow. (wikipedia.org)

This indicates that if the precise locations causing ischemia are better detected prior to stenting, patient outcomes may be improved. (philips.com)
The fact that nearly one-quarter of patients had residual ischemia despite an angiographically successful result, mostly due to focal lesions that can easily be treated, has important implications for improving outcomes of patients undergoing stent implantation globally," said Gregg W. Stone, MD, Professor of Medicine at Columbia University Medical Center. (philips.com)

We also found that female mice sustained smaller infarcts than males three months post- ischemia . (nih.gov)
Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia. (harvard.edu)

Pathology revealed gastric ischemia at the base of the wrap making it impossible to visualize through endoscopy. (sages.org)

Partial kidney ischemia-reperfusion (IR) injury is the principal cause of acute kidney injury. (hindawi.com)

0.001), and an "≥5 percent worsening ischemia was a strong, independent predictor of death or MI after adjustment for established predictors and irrespective of treatment arm. (acc.org)

Anatomy38

Organisms16

Diseases47

Chemicals and Drugs58

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Phenomena and Processes40

Disciplines and Occupations1

Health Care9

Mesenteric21

Limb ischaemia15

Focal ischemia2

Cardiac9

Transient7

Rats10

Model of myocardial2

Inhibition2

Chronic3

Coronary12

Global ischemia2

Silent ischemia4

Reperfusion-induced1

Renal4

Stroke6

Infarction5

Blockage1

Occurs2

Arteries6

Tissue3

Disorders1

Onset2

Neuronal4

Myocardium1

Sudden1

Underwent4

Occlusion1

Pathophysiology2

Diagnosis1

Brain20

Severe1

Angina1

Asymptomatic2

Artery2

Citation1

Outcomes2

Mice2

Pathology1

Cause of acute kidney1

Predictor1