Irradiation cardiac radiation cause cancer. Medical search. Frequent questions

I am Chair of the Department of Radiation Oncology and have been practicing medicine for 35 years. (mskcc.org)
Results from their pilot study suggested that step counts may serve as dynamic predictors of short-term hospitalization risk during chemoradiotherapy, and with his Innovative Projects in Radiation Oncology award, Dr. Ohri explored whether physical activity could also be used as a treatment. (roinstitute.org)
Future work includes validating this framework and expanding it to include brachytherapy, radioisotope therapy, and other cancer types to predict cell survival and treatment outcomes in a variety of precision oncology applications. (aapm.org)
Nowadays, the FLASH effect has the potential to revolutionize the field of radiation oncology and is investigated worldwide by various companies and academic institutions. (unil.ch)
Practical Radiation Oncology , 12 (3), 189-194. (researchwithrutgers.com)
Radiation oncology is the medical specialty concerned with prescribing radiation, and is distinct from radiology, the use of radiation in medical imaging and diagnosis). (medicalmarijuana.com)
Radiation Biology, Radiation Oncology and Cancer Imaging. (qub.ac.uk)
Physics and Imaging in Radiation Oncology. (qub.ac.uk)
These opportunities are a great way to contribute to the literature while reinforcing our ever-present, all-important goal: strengthening patient outcomes in radiation oncology. (appliedradiationoncology.com)
Advances in Radiation Oncology. (uib.no)
Health professionals, cancer clinicians and clinical scientists, scientists working in cancer, representatives of pharmaceutical companies involved in oncology, policy makers, post-doctoral researchers within medicine and science will benefit from participation in the conference. (cancerconference.ie)
Towards precision radiation oncology- does radiomics have a role? (cancerconference.ie)

Atrioventricular (AVN) and sinoatrial (SAN) nodes were retrospectively delineated according to published guidelines on the simulation computed tomography scans of 12 breast cancer patients having undergone conserving surgery and adjuvant locoregional volumetric modulated arc therapy. (allenpress.com)
Intensity-modulated proton therapy treatment was replanned on the simulation computed tomography scans for all breast cancer patients. (allenpress.com)
Cardiotoxicity studies evaluating conduction node exposure might define dose constraints and criteria for additional cardiac-sparing techniques, such as respiratory techniques or proton therapy, which could benefit patients with underlying rhythmic or conduction disorders. (allenpress.com)
Radiotherapy is delivered to over 50% of cancer patients with curative intent for solid localized tumours [ 1 ]. (frontiersin.org)
However, the risk of exposure of the surrounding normal tissues remains a concern for patient outcomes [ 2 ], with the potential for late tissue damage and escalating the risk of initiating secondary cancers in a patient's lifetime, especially for paediatric patients [ 3 ]. (frontiersin.org)
Methods and Materials: The trial included 1187 patients with T1-2 N0 breast cancer randomized to postoperative tangential whole breast RT or no further treatment. (lu.se)
We observed no increase in cardiac mortality in irradiated patients. (lu.se)
Therefore, identifying breast cancer patients at the highest risk for radiation-induced cardiac complications is crucial for developing strategies for primary and secondary prevention, which may contribute to healthy aging. (rug.nl)
Nitin Ohri, MD, and his team at the Montefiore Einstein Center for Cancer Care and Albert Einstein College of Medicine conducted a randomized clinical trial to determine if giving cancer patients daily customized step count goals as measured and guided through fitness trackers could improve their ability to tolerate concurrent chemoradiotherapy. (roinstitute.org)
Daily Step Counts Predict Outcomes for Locally Advanced Non-Small Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy was presented at the 2019 ASTRO Annual Meeting. (roinstitute.org)
Patients with small effusions (less than a few hundred milliliters) may present with a normal cardiac silhouette. (medscape.com)
Sixty-seven patients with gastric cancer of the antrum and body received distal gastrectomy. (cancerbiomed.org)
The therapeutic method of the operation combined with IORT did not prolong the survival time of patients with stage I and IV gastric cancer, but the 5-year survival rates of patients with stage II and III gastric cancers were significantly improved. (cancerbiomed.org)
Based on these considerations, we have used IORT for gastric cancer and report the clinical results in comparison with that of patients treated by operation alone. (cancerbiomed.org)
This past decade immunotherapy has demonstrated impressive responses in some cancer patients. (unil.ch)
In parallel, g rowing evidence suggests that the long-term neurocognitive changes as well as cardiac toxicity induced by anti-cancer treatments might differ between the sexes in both human cancer patients and in rodent models. (unil.ch)
Is adjuvant radiation therapy an alternative to regional node dissection in select patients with lymph node-positive melanoma? (appliedradiationoncology.com)
The Cancer of the Liver Italian Program (CLIP) classification [ 14 ] and the Chinese University Prognostic index (CUPI score) [ 15 ] tend to classify patients who have more advanced disease and are not descriptive enough to be able to distinguish those patients with lower volume of disease who may benefit the most from surgical intervention. (hindawi.com)
Patients and Methods: This study included 278 patients irradiated for locally advanced lung cancer between 2016 and 2019. (iiarjournals.org)
The majority of patients with small-cell lung cancer (SCLC) receive radiotherapy in combination with chemotherapy. (iiarjournals.org)
Also, many patients with locally advanced non-small-cell lung cancer (NSCLC) receive radiotherapy, if they are not candidates for surgery. (iiarjournals.org)
Radiation pneumonitis must be considered a serious complication that was reported to be fatal in approximately 2% of the patients ( 2 ). (iiarjournals.org)
Therefore, it would be desirable to identify patients, who are at high risk of developing radiation pneumonitis, prior to the start of treatment. (iiarjournals.org)
Therefore, this study was performed aiming to identify the prevalence of pneumonitis and potential risk factors for this complication in patients with locally advanced lung cancer irradiated with volume-modulated arc therapy (VMAT). (iiarjournals.org)
In this retrospective study, which was approved by the ethics committee of the University of Lübeck, 278 patients irradiated for locally advanced lung cancer between 2016 and 2019 were evaluated with respect to the development of symptomatic (grade ≥2) pneumonitis. (iiarjournals.org)
In the entire cohort of 278 patients, pneumonitis was diagnosed in 21 patients (7.6%) after a median of 9 weeks (range=1-23 weeks) following irradiation. (iiarjournals.org)
Purpose: Dosimetric and technical challenges often limit radiation therapy (RT) target coverage for patients with breast cancer who require bilateral breast/chest wall and regional nodal irradiation (RNI). (researchwithrutgers.com)
Conclusions: VMAT appears to be a feasible and tolerable RT modality for patients with breast cancer who require bilateral comprehensive adjuvant RT with RNI to obtain excellent target coverage. (researchwithrutgers.com)
Harris EE, et al Late cardiac mortality and morbidity in early-stage breast cancer patients after breast-conservation treatment. (visionrt.com)
Should Prophylactic Cranial Irradiation Be Used in Patients with Stage III Non-Small Cell Lung Cancer? (libsyn.com)
Racial Disparity in Tumor Microenvironment and Outcomes in Residual Breast Cancer after Neoadjuvant Chemotherapy Karadal Ferrena, Burcu Black patients with residual estrogen receptor-positive (ER+) breast cancer after neoadjuvant chemotherapy (NAC) have inferior survival compared to white women resulting racial disparity in breast cancer survival. (hacettepe.edu.tr)
In conclusion, high-TMEM doorway score was an independent prognostic factor of worse survival in patients with residual cancer post-NAC. (hacettepe.edu.tr)
Bortezomib ve İmatinib'in Pankreas Kanserinde Olası Sinerjistik Etkisinin İncelenmesi Pişiren, Gaye The high mortality rate among pancreatic cancer patients underlines the importance of proper treatment. (hacettepe.edu.tr)
Optimiser les soins des patients atteints du cancer de la prostate résistant à la castration en utilisant une stratégie de triple traceur en imagerie moléculaire et en radiothérapie ciblée. (usherbrooke.ca)
Radiotherapy, including internal mammary nodal irradiation, and heart failure in patients receiving concurrent treatment with trastuzumab further explores the critical challenge of RT-induced cardiotoxicity. (appliedradiationoncology.com)
Most patients saved from cancer are cured by a local regional treatment, in which radiotherapy plays a prominent role. (labex-lermit.fr)
Despite the fact that radiotherapy is one of the most effective forms of cancer treatment, one third of the patients who died from cancer died of a loco-regional failure, underlining the absolute need to optimize the antitumor efficacy of radiotherapy. (labex-lermit.fr)
Considering thattreatment-related comorbidities are major issues for irradiated long-term cancer survivors,the decrease of treatment-associated side effects (such as cardiovascular diseases) is needed for patients who are cured by radiotherapy. (labex-lermit.fr)
The very brief examination times allow both very young patients and patients with renal insufficiency to be examined without a severe health hazard due to high doses of contrast medium (damaging to the kidneys) or having to endure irradiation. (primomedico.com)
nausea and vomiting associated with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen. (nih.gov)
radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen. (nih.gov)
This randomized phase III trial compares giving radiation therapy alone or temozolomide together with radiation therapy and to see which works best in treating patients with newly diagnosed anaplastic glioma or low grade glioma. (sncrf.org)
Objectives: Radiotherapy improves the survival rate of cancer patients, yet it also involves some inevitable complications. (sciencegate.app)
Investigating the relationship between KIN17 and neoplasms will provide a vital theoretical basis for KIN17 to serve as a diagnostic and prognostic biomarker for cancer patients and as a potential target for cancer therapy. (spandidos-publications.com)
Patients with severe acute radiation sickness receive reverse isolation, antimicrobial and anti-inflammatory agents, and bone marrow support. (msdmanuals.com)
Delayed cardiotoxicity may occur in patients with prior mediastinal irradiation, in those on concurrent cyclophosphamide therapy, or in those with preexisting heart disease. (medscape.com)
Can Multigene Testing Provide Additional Risk Stratification for Patients Considered Eligible for Accelerated Partial Breast Irradiation? (cdc.gov)
The 70-gene signature test as a prognostic and predictive biomarker in patients with invasive lobular breast cancer. (cdc.gov)
Impact of the 21-Gene Recurrence Score Assay on the Treatment of Estrogen Receptor-Positive, HER2-Negative, Breast Cancer Patients With 1-3 Positive Nodes: A Prospective Clinical Utility Study. (cdc.gov)
Effectiveness of a surveillance program of upper endoscopy for upper gastrointestinal cancers in Lynch syndrome patients. (cdc.gov)
Perspectives on the factors affecting decisions around Lynch syndrome genetic testing and results sharing for high-risk colorectal cancer patients. (cdc.gov)

Arrhythmias and conduction disorders are described as radiation-induced complications of thoracic irradiations [ 5 ]. (allenpress.com)
The observed increase in stroke mortality may partly be secondary to cardiac side effects, complications to anticoagulant treatment, or to chance, rather than a direct side effect of tangential whole breast irradiation. (lu.se)
There is still a need for precise knowledge on the relationship between radiation dose to specific cardiac structures and early subclinical cardiac changes and their occurrence over time that could finally lead to cardiac complications. (rug.nl)
We are watching for a possible relapse of cancer or immediate complications from cancer treatments. (asso.fr)
However, serious complications I was telling you about earlier, that may occur and which are called sequels, can exist, but from a few months to a few years later, even 5 years, 10 years, 15 years, 30 years after radiation therapy. (asso.fr)
For irradiation concerning the internal mammary chain, there were, for example, cardiac complications that have been observed in recent years, or for a radiation to the Axilla and sub-clavicular, radio-induced plexopathies. (asso.fr)
RhoB had a causative role in the development of these radiation-induced complications in various organs (including the heart, lung and gut). (unil.ch)
Rare but severe extraskeletal complications may occur, ranging from gastrointestinal reflux to cardiac involvement with arrhythmias and even sudden death. (medscape.com)
Radiation-induced heart disease (RIHD) is one of the most serious complications, especially the radiotherapy of thoracic tumors, which is characterized by cardiac oxidative stress disorder and programmed cell death. (sciencegate.app)

Women treated with radiotherapy without chemotherapy for a unilateral breast cancer and aged 40-75 years meet the inclusion criteria. (rug.nl)
Without radiation therapy, there is no cure for cancer, obviously associated with surgery and/or chemotherapy. (asso.fr)
A decline in ejection fraction occurred in one patient with a preexisting cardiac condition who also received anthracycline-based chemotherapy and trastuzumab. (researchwithrutgers.com)
It is also common to combine radiation therapy with surgery, chemotherapy, hormone therapy, Immuno-therapy or some mixture of the four. (medicalmarijuana.com)
nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy. (nih.gov)
initial and repeat courses of moderately emetogenic cancer chemotherapy. (nih.gov)
3 months earlier) with grade 2 or 3 gliomas are eligible if the patient has not received prior radiation or prior chemotherapy. (sncrf.org)

Akciğer Kanseri ve Sol Meme Radyoterapisinde Kardiyak Altyapı Marjlarının Oluşturulması ve Tedavi Planı Optimizasyonu Dalgıç, Eylem In thoracic irradiations, the coronary arteries (CA) are involuntarily exposed to radiation and subsequent cardiovascular toxicities may occur. (hacettepe.edu.tr)

For example, pelvic irradiation for cancer of the rectum, prostate or the collar, a frequent event is the presence of digestive disorders. (asso.fr)
5. Any contraindication to pelvic irradiation as evaluated by the investigator. (who.int)

Adjuvant breast radiation therapy is associated with increased locoregional control and patient-specific survival [ 1 ]. (allenpress.com)
He later also treated Sigmund Freud, making an unsuccessful adjuvant irradiation attempt for Freud's oral cavity squamous cell carcinoma (to which Freud eventually succumbed). (wikipedia.org)
Radiation may be prescribed by a radiation oncologist with intent to cure ("curative") or for adjuvant therapy. (medicalmarijuana.com)
The cover article, Cardiac-sparing radiation therapy for breast cancer, examines the wide variety of methods for adjuvant breast or chest wall RT that can help minimize radiation dose to the heart-a key contributor to coronary stenosis and other cardiac diseases. (appliedradiationoncology.com)

The exposition of cardiac conduction system during breast radiation therapy has never been studied, despite the increasing use of intensity-modulated radiation therapy, which exposes larger volume to low-dose bath. (allenpress.com)
We evaluated conduction node exposure during breast irradiation with volumetric modulated arc therapy and estimated the potential dosimetric benefit with intensity-modulated proton therapy. (allenpress.com)
SAN and AVN can be substantially exposed during breast volumetric modulated arc therapy, especially for right-sided irradiation. (allenpress.com)
Such techniques include rotational intensity-modulated radiation therapy (IMRT) or proton therapy. (allenpress.com)
Deep inspiration breath hold is a radiation therapy technique. (petermac.org)
Deep Inspiration Breath Hold can be useful when you need radiation therapy in your chest region. (petermac.org)
As a result, your radiation therapy team will assess your suitability. (petermac.org)
We deliver Deep Inspiration Breath Hold techniques at our five radiation therapy sites. (petermac.org)
Your radiation therapy team will be there to help and coach you. (petermac.org)
What are the principles of radiation therapy in the definitive management of stage III inoperable NSCLC? (cancer.org.au)
Improved accuracy in target volume delineation and radiation therapy delivery has the potential to improve treatment outcomes in NSCLC by facilitating radiation dose escalation and ensuring geographic misses are avoided. (cancer.org.au)
Purpose: Radiation therapy (RT) after breast-conserving surgery reduces locoregional recurrences and improves survival but may cause late side effects. (lu.se)
This framework's capabilities were demonstrated using external-beam fractionated proton therapy for treating breast cancer tumors. (aapm.org)
and radiotherapy, still the most "noble", a curative radiation therapy that can cure 50% of cancers. (asso.fr)
My group has been the first to develop FLASH-Radiotherapy, a novel modality of radiation therapy at ultra high dose rate that minimizes normal tissue toxicity but eradicates tumors. (unil.ch)
Next, using a lung adenocarcinoma model (KP), we demonstrated that modulation of neutrophil phenotype was able to enhance the tumor response to radiation therapy without any stimulation of fibrosis. (unil.ch)
Post-operative radiation therapy is the common treatment of breast cancer, which can reduce the locoregional recurrent rate. (e-roj.org)
Many techniques are applied, such as intensity-modulated radiation therapy or volumetric modulated radiation therapy used for bilateral breast irradiation [ 1 ], breathing controlled used for left side breast irradiation. (e-roj.org)
Utility of Deep inspiration breath-hold for left sided breast radiation therapy in preventing early cardiac perfusion defects - A Prospective Study. (visionrt.com)
Commissioning and performance testing of the first prototype of AlignRT InBore™ a Halcyon™ and Ethos™-dedicated surface guided radiation therapy platform. (visionrt.com)
SPECT analysis of cardiac perfusion changes after whole-breast/chest wall radiation therapy with or without active breathing coordinator: results of a randomized phase 3 trial. (visionrt.com)
Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. (medicalmarijuana.com)
Most common cancer types can be treated with radiation therapy in some way. (medicalmarijuana.com)
Total body irradiation (TBI) is a radiation therapy technique used to prepare the body to receive a bone marrow transplant. (medicalmarijuana.com)
Brachytherapy, in which a radiation source is placed inside or next to the area requiring treatment, is another form of radiation therapy that minimizes exposure to healthy tissue during procedures to treat cancers of the breast, prostate and other organs. (medicalmarijuana.com)
Radiation therapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, and prevention of keloid scar growth, vascular restenosis , and heterotopic ossification. (medicalmarijuana.com)
The use of radiation therapy in non-malignant conditions is limited partly by worries about the risk of radiation-induced cancers. (medicalmarijuana.com)
Radiation therapy works by damaging the DNA of cancerous cells. (medicalmarijuana.com)
In the older, most common form of radiation therapy, Intensity-modulated radiation therapy (IMRT) (photons), most of the radiation effect is through free radicals. (medicalmarijuana.com)
One of the major limitations of photon radiation therapy is that the cells of solid tumors become deficient in oxygen. (medicalmarijuana.com)
Overall, our study discovered the previously unknown effects of imatinib and bortezomib in pancreatic cancer cells and indicated that activation of ER stress induced death might be used as a therapy option for pancreatic cancer treatment. (hacettepe.edu.tr)
As a prelude to Breast Cancer Awareness Month coming up in October, we are pleased to focus this issue on several evolving areas of breast radiation therapy. (appliedradiationoncology.com)
University of Pennsylvania authors provide an enlightened review of techniques to help individualize and, in turn, maximize cardiac-sparing radiation treatments, from a minimum standard of forward planning, to more advanced methods of prone positioning, deep-inspiration breath hold, intensity-modulated radiation therapy, and proton therapy. (appliedradiationoncology.com)
This definitive review assesses applicator-based brachytherapy and its toxicity-related concerns, external-beam approaches, proton therapy, intraoperative radiation therapy, and the future outlook of APBI. (appliedradiationoncology.com)
Finally in our breast cancer lineup, we present Soft tissue sarcoma of the breast following breast-conserving therapy, a helpful case report describing the challenge of re-irradiating the left chest while managing heart and lung dose. (appliedradiationoncology.com)
Radiation therapy is a cornerstone of cancer management. (labex-lermit.fr)
Plan selection in proton therapy of locally advanced prostate cancer with simultaneous treatment of multiple targets. (uib.no)
Linear energy transfer distributions in the brainstem depending on tumour location in intensity-modulated proton therapy of paediatric cancer. (uib.no)
Biological dose and complication probabilities for the rectum and bladder based on linear energy transfer distributions in spot scanning proton therapy of prostate cancer. (uib.no)
Modelling of organ-specific radiation-induced secondary cancer risks following particle therapy. (uib.no)
Out-of-field dose in contemporary radiation therapy. (sbcrowe.net)
Radiation therapy uses high-energy x-rays to kill tumor cells. (sncrf.org)
It is not yet known whether giving radiation therapy alone or temozolomide together with radiation therapy is better in treating anaplastic glioma or low grade glioma. (sncrf.org)
7. Any investigational anti-cancer therapy other than the protocol specified therapies (participation in other prospective studies which do not imply any specific intervention may be allowed after discussion with the Study Chair). (who.int)
E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. (wisc.edu)
Forsberg MH, Kink JA, Thickens AS, Lewis BM, Childs CJ, Hematti P, Capitini CM. Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome . (wisc.edu)
Ionizing radiation is emitted by radioactive elements and by equipment such as x-ray and radiation therapy machines. (msdmanuals.com)

The heart is a complex organ at risk, and the multiplicity of its substructures explains the vast range of described radiation-induced cardiotoxicity types [ 4 ]. (allenpress.com)
Cardiotoxicity After Breast Cancer Radiotherapy: Which Part of the Heart Matters Most? (libsyn.com)

Average mean doses delivered to the SAN and AVN were 2.8 and 2.3 Gy, respectively, for left-sided irradiation and 9.6 and 3.6 Gy, respectively, for right-sided irradiation. (allenpress.com)
Average maximum doses to the SAN and AVN were 3.5 Gy and 2.8 Gy, respectively, for left-sided irradiation and 13.1 and 4.6 Gy, respectively, for right-sided irradiation. (allenpress.com)
It lets us avoid radiation doses to your heart. (petermac.org)
We demonstrated the utility of this framework using a validated breast cancer monolayer model and tracked tumor evolution in 4 cases: no treatment and three external-beam 50 MeV proton doses: single 4-Gy fraction early in tumor development, single 20-Gy fraction late in tumor development, and a 40-Gy cumulative dose delivered over 10 fractions. (aapm.org)
Background/Aim: Radiotherapy of locally advanced lung cancer often requires high doses potentially leading to pneumonitis. (iiarjournals.org)
Therefore, high radiation doses are often required that may lead to pneumonitis. (iiarjournals.org)

Irradiation techniques have evolved and currently can efficiently spare the heart and its critical substructures, such as the coronary arteries, even in the case of unfavorable anatomy [ 2 , 3 ]. (allenpress.com)
Baseline and follow-up data include cardiac measurements based on two-dimensional speckle-tracking echocardiography, computed tomography coronary angiography, cardiac magnetic resonance imaging, and a wide panel of circulating biomarkers of cardiac injury. (rug.nl)
This podcast includes commentary upon a large case control series that examined the incidence of cardiac injury in association with radiation dose to distinct segments of the left ventricle and coronary arteries. (libsyn.com)

With the development of cardiac conduction system delineation atlases [ 6 ], evaluating the relationship between conduction disorders or arrhythmias and conduction substructure exposure has become possible. (allenpress.com)
Radiological exposure, especially internal irradiation, can cause not only cancer or leukemia but also many forms of cell deaths or cell damage in important human organs including blood vessels, heart muscles and brain nerve cells. (uchicago.edu)
Previous results showed some unexpected and potentially concerning effects of cosmic radiation exposure on the brain and investigating the impact of cosmic rays on cognitive function of animals is required to determine whether travel to Mars will be possible for Astronauts. (unil.ch)
In this project, we specifically investigate the impact of brain exposure to Pion irradiation taking advantage of the ONLY pion beam available worldwide at the Paul Scherrer Institute (PSI) in Villigen (CH). (unil.ch)
Exposure to radioactive substances increases one's risk of developing cancer. (ibilabs.com)
Prolonged exposure to uranium compounds may cause kidney damage and elevated cancer risk. (ibilabs.com)
To spare normal tissues (such as skin or organs which radiation must pass through in order to treat the tumor), shaped radiation beams are aimed from several angles of exposure to intersect at the tumor, providing a much larger absorbed dose there than in the surrounding, healthy tissue. (medicalmarijuana.com)
Purpose: Current Monte Carlo simulations modeling space radiation exposure typically use simplistic human phantoms with low anatomical detail and minimal variability in physical characteristics. (duke.edu)
In comparison with conventional CT apparatuses, the radiation dose is reduced by up to 90% (radiation exposure is markedly lower than e.g. for a transatlantic flight). (primomedico.com)
Ionizing radiation injures tissues variably, depending on factors such as radiation dose, rate of exposure, type of radiation, and part of the body exposed. (msdmanuals.com)
Diagnosis is by history of exposure, symptoms and signs, and sometimes use of radiation detection equipment to localize and identify radionuclide contamination. (msdmanuals.com)

The incidence and functional consequences of RT-associated cardiac perfusion defects. (visionrt.com)

Objective: The MEDIRAD EARLY HEART study aims to identify and validate new cardiac imaging and circulating biomarkers of radiation-induced cardiovascular changes arising within first 2 years of breast cancer radiotherapy and to develop risk models integrating these biomarkers combined with precise dose metrics of cardiac structures based on three-dimensional dosimetry. (rug.nl)
9. Clinically significant (i.e., active) cardiovascular disease: cerebral vascular accident/stroke, myocardial infarction, unstable angina, congestive heart failure (grade III or IV as classified by the New York Heart Association), or serious cardiac arrhythmia requiring medication within the past 6 months. (who.int)

There has also been an increase in the donor pool with marginal donors including organs retrieved following cardiac death being used. (hindawi.com)
Aided by this, all the organs of the body can be investigated more gently in the most precise detail and with the lowest radiation dose to date. (primomedico.com)
The high-end computer tomograph is not just impressive because of its greater speed, low contrast medium requirement and low radiation dose, but rather because the organs of the body can also be depicted in four-dimensional space (4-D technique). (primomedico.com)
Acute radiation syndromes can be caused by a sufficient dose of some internally deposited radionuclides that are widely distributed in tissues and organs and have a high specific activity. (msdmanuals.com)

Neurocognitive and cardiac toxicity are severely impacting cancer survivors' quality of life. (unil.ch)
The identification of new combinatory strategies that could enhance the antitumor effect of the irradiation, without increasing the treatment-related toxicity is essential for radiotherapy. (labex-lermit.fr)

According to the Fukushima Prefectural government, 209 children have been diagnosed with child thyroid cancer. (uchicago.edu)

Results: The cumulative incidence of cardiac mortality was 12.4% in the control group and 13.0% in the RT group (P = .8). (lu.se)
Normally, without irradiation, the incidence is about one in a million per year. (uchicago.edu)

monitor with electrocardiograms (ECGs) if concomitant electrolyte abnormalities, cardiac failure or arrhythmias, or use of other QT prolonging drugs. (nih.gov)

In IORT a large single dose of radiation is given to the area where the risk of local failure is greatest. (cancerbiomed.org)
Especially for the left breast irradiation, a low dose of radiation may induce the late complication to the heart such as the morbidity and mortality, even though the complication may also arise from other factors, such as systemic treatment and patient's comorbidities [ 3 ]. (e-roj.org)
Oxygen is a potent radio-sensitizer, increasing the effectiveness of a given dose of radiation by forming DNA-damaging free radicals. (medicalmarijuana.com)

A sharp increase in cardiac infarctions, heart failures, sudden deaths, strokes, and Alzheimer diseases have been reported since the Fukushima nuclear disaster. (uchicago.edu)

Analysis of Sociodemographic, Clinical, and Genomic Factors Associated With Breast Cancer Mortality in the Linked Surveillance, Epidemiology, and End Results and Medicare Database. (cdc.gov)
The profile of the clinical variables presented by the children and adolescents of this study shows that the most prevalent diagnosis was ALL, the most frequent toxicities were gastrointestinal, cardiac, respiratory and hematological, the most common HSCT was allogeneic peripheral blood and the greatest cause of mortality was sepsis. (bvsalud.org)

Incidences of contralateral breast cancer and lung cancer were similar between groups. (lu.se)
Daily Step Counts: A New Prognostic Factor in Locally Advanced Non-Small Cell Lung Cancer? (roinstitute.org)
Cardiac Dosing Predicts Activity Decline During Concurrent Chemoradiation for Locally Advanced Lung Cancer was presented at the 2018 ASTRO Annual Meeting. (roinstitute.org)
Histologically or pathologically confirmed extensive stage small cell lung cancer (ES-SCLC). (swog.org)
Lung cancer remains the leading cause of cancer death in the United States. (appliedradiationoncology.com)
Lung cancer is the second most common solid cancer in Europe and Northern America ( 1 ). (iiarjournals.org)
Moreover, in the literature, the prevalence of symptomatic pneumonitis after irradiation of lung cancer varies considerably ( 4 - 7 ). (iiarjournals.org)
This is an evaluation of PCI in stage III Non-Small-Cell Lung Cancer. (libsyn.com)
Gene-Guided Treatment Decision-Making in Non-Small Cell Lung Cancer - A Systematic Review. (cdc.gov)

https://wiki.cancer.org.au/australiawiki/index.php?oldid=146699 , cited 2023 Sep 25]. (cancer.org.au)

No secondary cancers have been noted to date. (researchwithrutgers.com)

DIBH is one of the many ways we can reduce the radiation dose to your heart. (petermac.org)
One of the advanced treatment techniques which are more sophisticated to reduce the radiation dose to the heart is deep inspiration breath hold (DIBH) technique. (e-roj.org)

However, breast irradiation treatment usually consists of medial and tangential beams designed to reduce radiation dose to the underlying heart and healthy lung tissue [ 2 ]. (e-roj.org)

We developed an automated computational multiscale framework for precision dosimetry to track radiation effects at the cellular to whole-body scale. (aapm.org)

Röntgenologische Diagnostik der Erkrankung der Brusteingeweide (Radiological diagnostics of breast cancer), 1901 Röntgendiagnostik des Magenkrebses (1905). (wikipedia.org)
Any area in nuclear facilities or hospitals etc. where radiation levels can exceed 1.3 milli-sieverts(mSv) in 3 month period (5.2 mSv/year) or 40,000bq/m2 is designated as a 'radiological control area. (uchicago.edu)
As well as the diagnostic range consisting of magnetic resonance tomography, nuclear medicine and radiological diagnostics, together with its state of the art facilities, with premium high-tech devices, the Heidelberg Radiology Practice has been equipped with the world's latest low-radiation high-end computer tomograph, the Somatom Force by the Siemens company, since November 2014. (primomedico.com)

History of radiation pneumonitis in the radiation field (fibrosis) is permitted. (swog.org)

It is made with ionizing radiation and delivers an energy aimed at a specific tissue, in order to kill tumor cells. (asso.fr)
Ionizing radiation works by damaging the DNA of exposed tissue, furthermore, it is believed that cancerous cells may be more susceptible to death by this process as many have turned off their DNA repair machinery during the process of becoming cancerous. (medicalmarijuana.com)
We stained 183 invasive ductal carcinoma tissue samples (96 Black women, 87 white women) for TMEM doorways (Pan-Mena expressing tumor cell, CD68 macrophages, and CD31 endothelial cells) and SOX9 expressing cancer stem cells (CSCs). (hacettepe.edu.tr)
Gamma radiation and x-rays are electromagnetic radiation (ie, photons) of very short wavelength that can penetrate deeply into tissue (many centimeters). (msdmanuals.com)

Total number of 112 cases of left-sided breast cancer were analyzed. (e-roj.org)

miR-223-3p mimic significantly relieved, while miR-223-3p inhibitor aggravated apoptosis, oxidative damage, and cardiac dysfunction in RIHD mice. (sciencegate.app)

In Accelerated partial-breast irradiation (APBI): An emerging standard of care, Cleveland Clinic authors evaluate data supporting this underused, yet proven, technique for women with early stage breast cancer who have undergone breast-conserving surgery. (appliedradiationoncology.com)

Partner with us to treat your patient's cancer. (mskcc.org)

Radiation Measurements. (uib.no)

In the hope of generalizing the efficacy of radio-immunotherapy to all cancer paptients, we are developing preclinical strategies to better understand the modulation induced by irradiation on the microenvironment. (unil.ch)

Y. Tanaka, K. Matsuo and S. Yuzuriha, "Near-Infrared Irradiation Non-Thermally Induces Long-Lasting Vasodilation by Causing Apoptosis of Vascular Smooth Muscle Cells," ePlasty, Vol. 11, 2011, p. e22. (scirp.org)

This provides new opportunities, particularly in the area of the early recognition of cancer conditions and circulatory disorders of the heart, the lungs and the large vessels in various areas of the body, in particular, as well, in the region of the targeted investigation of the head and neck vessels in the diagnosis of a cerebrovascular accident. (primomedico.com)
Due to the increased susceptibility to the development of cancer in this specific population, it is important for the dentist to know the common oral manifestations and potentially cancerous lesions, in order to make an early diagnosis in individuals with Fanconi Anemia. (bvsalud.org)

The clinical results of IORT for gastric cancer were analyzed based on the histologic findings. (cancerbiomed.org)
Clinical trials with domestic animals (cats with spontaneous cancer), in col with Zurich Vet School, Pr C Rohrer. (unil.ch)

RNA-seq profile of African American men with a clinically localized prostate cancer. (cdc.gov)
NCCN Risk Reclassification in Black men with low and intermediate risk Prostate Cancer after genomic testing. (cdc.gov)

Inter-patient variations in relative biological effectiveness for cranio-spinal irradiation with protons. (uib.no)
They collide with the nuclei of stable atoms, resulting in the emission of energetic protons, alpha and beta particles, and gamma radiation. (msdmanuals.com)

Background: Breast cancer is the most common cancer among women, and radiotherapy plays a major role in its treatment. (rug.nl)
The French Classification [ 16 ] and the Japan Integrated Staging (JIS), which has recently been refined to include biomarkers (AFP, DCP, and AFP-L-3) [ 17 ], are also staging systems but do not assign treatment allocation to specific prognostic subclasses as opposed to the Barcelona Liver Cancer Staging system (BCLC). (hindawi.com)
Breast cancer is a common challenge in radiotherapy due to a variety of treatment conditions. (e-roj.org)
A Voluntary Breath-Hold Treatment Technique for the Left Breast With Unfavorable Cardiac Anatomy Using Surface Imaging. (visionrt.com)
Translational cancer research has been around for many years and has resultedin many advancements in cancer treatment. (duke.edu)
The active protein synthesis in pancreas emphasizes the need for a stringent central of protein homeostasis thus bortezomib might be a good candidate for pancreatic cancer treatment. (hacettepe.edu.tr)
11. Any previous treatment for rectal cancer. (who.int)
How Does Invasive Breast Cancer Oncotype Dx Recurrence Score on Core Needle Biopsies Influence Neoadjuvant Treatment Decision? (cdc.gov)

Y. Tanaka, K. Matsuo and S. Yuzuriha, "Long-Lasting Muscle Thinning Induced by Infrared Irradiation Specialized with Wavelength and Contact Cooling: A Preliminary Report," ePlasty, Vol. 10, 2010, p. e40. (scirp.org)

Cancer cells generally are undifferentiated and stem cell-like, they reproduce more, and have a diminished ability to repair sub-lethal damage compared to most healthy differentiated cells. (medicalmarijuana.com)
This single-strand DNA damage is then passed on through cell division, accumulating damage to the cancer cell's DNA, causing them to die or reproduce more slowly. (medicalmarijuana.com)
Tumor cells in a hypoxic environment may be as much as two to three times more resistant to radiation damage than those in a normal oxygen environment. (medicalmarijuana.com)
Direct damage to cancer cell DNA occurs through high-LET (linear energy transfer) charged particles such as proton, boron, carbon or neon ions which have an antitumor effect which is independent of tumor oxygen supply because these particles act mostly via direct energy transfer usually causing double-stranded DNA breaks. (medicalmarijuana.com)
KIN17, which is known as a DNA and RNA binding protein, is highly expressed in numerous types of human cancers and was discovered to participate in several vital cell behaviors, including DNA replication, damage repair, regulation of cell cycle and RNA processing. (spandidos-publications.com)

Risk of ischemic heart disease in women after radiotherapy for breast cancer. (visionrt.com)

Furthermore, the dose-response relationship will allow modeling the radiation-induced occurrence and evolution of subclinical cardiac lesions and biomarkers to develop prediction models. (rug.nl)

Our framework consists of a parallelizable automated pipeline that combines multicellular phenomenological models for tumor growth, extended cardiac-torso (XCAT) phantoms for organ-level precision, and GEANT4 to track radiation dose. (aapm.org)
[ 1 - 3 ] It is fortunate because basic oncologic and radiotherapeutic data leave no doubt that radiation thus applied should be able to control tumor growth. (cancerbiomed.org)

staining, score as abnormal Table 3-1 CANDIDATES FOR GERMLINE GENETIC TESTING a Breast cancer diagnosed at or before age 50 years Ovarian cancer Multiple primary breast cancers in one or both breasts Male breast cancer Triple-negative (estrogen receptor-negative, progesterone. (arppress.org)

I am a radiation oncologist who cares for people with breast cancer . (mskcc.org)

Besides the tumor itself, the radiation fields may also include the draining lymph nodes if they are clinically or radiologically involved with tumor, or if there is thought to be a risk of subclinical malignant spread. (medicalmarijuana.com)

Common associated signs and symptoms include low-grade intermittent fever, dyspnea/tachypnea (a frequent complaint and may be severe, with myocarditis, pericarditis, and cardiac tamponade), cough, and dysphagia. (medscape.com)

However, breast cancer radiotherapy can lead to incidental irradiation of the heart, resulting in an increased risk for a variety of heart diseases arising many years after radiotherapy. (rug.nl)

Anatomy13

Organisms7

Diseases53

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment81

Psychiatry and Psychology1

Phenomena and Processes55

Disciplines and Occupations5

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture1

Information Science10

Named Groups1

Health Care44

Geographicals2

Oncology12

Patients51

Complications9

Chemotherapy7

Thoracic irradiations1

Pelvic irradiation2

Adjuvant4

Therapy47

Cardiotoxicity2

Doses6

Coronary3

Exposure11

Perfusion1

Cardiovascular2

Organs4

Toxicity2

Thyroid1

Incidence2

Arrhythmias1

Dose of radiation3

Increase in cardiac1

Mortality2

Lung cancer9

20231

Secondary cancers1

DIBH2

Tangential1

Dosimetry1

Radiological3

Pneumonitis1

Tissue4

Left-sided1

DYSFUNCTION1

Partial-breast1

Patient's1

Measurements1

Microenvironment1

Apoptosis1

Diagnosis2

Clinical2

Prostate2

Protons2

Treatment8

Wavelength1

Damage5

Radiotherapy for Breast Cancer1

Lesions1

Tumor growth2

Ovarian Cancer1

Oncologist1

Lymph1

Myocarditis1

Breast cancer radiotherapy1